| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M P Castelli, I Mocci, A M Sanna, G L Gessa, L Pan. (-)S amisulpride binds with high affinity to cloned dopamine D(3) and D(2) receptors. European journal of pharmacology. vol 432. issue 2-3. 2002-01-16. PMID:11740949. |
both racemic and the (-)s enantiomer exhibited 2-4 ([3h]spiperone)- and 3-4 ([3h]nemonapride)-fold higher affinity than haloperidol for dopamine rd(3) receptor, respectively. |
2002-01-16 |
2023-08-12 |
human |
| M P Castelli, I Mocci, A M Sanna, G L Gessa, L Pan. (-)S amisulpride binds with high affinity to cloned dopamine D(3) and D(2) receptors. European journal of pharmacology. vol 432. issue 2-3. 2002-01-16. PMID:11740949. |
the (+)r enantiomer has weaker affinity with respect to haloperidol for both dopamine hd(2l) and dopamine rd(3) receptors. |
2002-01-16 |
2023-08-12 |
human |
| H Miwa, T Fuwa, K Nishi, T Kond. Subthalamo-pallido-striatal axis: a feedback system in the basal ganglia. Neuroreport. vol 12. issue 17. 2002-01-11. PMID:11726797. |
systemic administration of a dopamine d2 receptor blocker, haloperidol, but not vehicle, significantly increased the number of c-fos-immunoreactive neurons in the globus pallidus (gp) in rats. |
2002-01-11 |
2023-08-12 |
rat |
| M Markianos, L Lykouras, G Moussas, J Hatzimanoli. Changes in dopamine receptor responsivity during alcohol detoxification may predict relapse. Drug and alcohol dependence. vol 64. issue 3. 2002-01-03. PMID:11672950. |
the patients had been tested earlier during their usual alcohol consumption and immediately after detoxification for the responsivity of d2 dopamine receptors (as measured by the increases in prolactin plasma levels caused by intramuscular administration of 5 mg of the dopamine receptor blocker haloperidol). |
2002-01-03 |
2023-08-12 |
human |
| M Boules, B McMahon, L Warrington, J Stewart, J Jackson, A Fauq, D McCormick, E Richelso. Neurotensin analog selective for hypothermia over antinociception and exhibiting atypical neuroleptic-like properties. Brain research. vol 919. issue 1. 2002-01-03. PMID:11689157. |
in studies using in vivo microdialysis nt77l showed similar effects on dopamine turnover to those of clozapine, and significantly different from those of haloperidol in the striatum. |
2002-01-03 |
2023-08-12 |
rat |
| Y Adachi, H Wada, H Higuchi, K Watanabe, T Sato. [The effect of halothane anesthesia on dopamine release induced by apomorphine or haloperidol--an in vivo microdialysis study in rats striatum]. Masui. The Japanese journal of anesthesiology. vol 50. issue 10. 2001-12-28. PMID:11712340. |
[the effect of halothane anesthesia on dopamine release induced by apomorphine or haloperidol--an in vivo microdialysis study in rats striatum]. |
2001-12-28 |
2023-08-12 |
rat |
| A Berlin. Effects of haloperidol and phentolamine on the crustacean cardiac ganglion. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 130. issue 1. 2001-12-17. PMID:11544145. |
haloperidol (a dopamine d2 blocker in vertebrates) and phentolamine (an alpha-adrenergic blocker) alter the pattern of bursting by the isolated cardiac ganglion of the lobster when perfused at concentrations of 10(-6)-10(-5) mol/l. |
2001-12-17 |
2023-08-12 |
lobster |
| S Kähkönen, J Ahveninen, E Pekkonen, S Kaakkola, J Huttunen, T Peltonen, R J Ilmoniemi, I P Jääskeläine. No evidence for dependence of early cortical auditory processing on dopamine D(2)-receptor modulation: a whole-head magnetoencephalographic study. Psychiatry research. vol 107. issue 2. 2001-12-07. PMID:11530277. |
in a double-blind, randomized, placebo-controlled, cross-over design study, the dopamine d(2) receptor antagonist haloperidol (2 mg) was given orally to 12 healthy volunteers. |
2001-12-07 |
2023-08-12 |
human |
| P L Vera, I Nadelhaf. Effects of the atypical neuroleptic clozapine on micturition parameters in anesthetized rats. Neurourology and urodynamics. vol 20. issue 5. 2001-12-04. PMID:11574938. |
since both clozapine and haloperidol have interactions with other transmitter systems beside dopamine, we suggest that central antagonism of d2 receptors, coupled to central antagonism of another receptor system and peripheral muscarinic receptor blockade, may account for clozapine's potent effects on micturition. |
2001-12-04 |
2023-08-12 |
rat |
| K J Stanhope, N R Mirza, M J Bickerdike, J L Bright, N R Harrington, M B Hesselink, G A Kennett, S Lightowler, M J Sheardown, R Syed, R L Upton, G Wadsworth, S M Weiss, A Wyat. The muscarinic receptor agonist xanomeline has an antipsychotic-like profile in the rat. The Journal of pharmacology and experimental therapeutics. vol 299. issue 2. 2001-12-04. PMID:11602695. |
finally, haloperidol, clozapine, pilocarpine, and xanomeline, all induced an increase in dopamine turnover in medial prefrontal cortex. |
2001-12-04 |
2023-08-12 |
rat |
| T Hirayama, T Kita, Y Ogawa, H Ohsawa, M Yamashita, T Nakashima, T Kishimot. Effect of chronic treatment with haloperidol on vasopressin release and behavioral changes by osmotic stimulation of the supraoptic nucleus. Life sciences. vol 69. issue 18. 2001-12-04. PMID:11669458. |
to investigate the relationship between dopamine d2 blockers and these syndromes, we designed a behavioral and neurochemical study using hyperosmotic stimulation in the supraoptic nucleus (son) by microdialysis after chronic treatment with haloperidol in rats. |
2001-12-04 |
2023-08-12 |
rat |
| J Mukherjee, B T Christian, T K Narayanan, B Shi, J Manti. Evaluation of dopamine D-2 receptor occupancy by clozapine, risperidone, and haloperidol in vivo in the rodent and nonhuman primate brain using 18F-fallypride. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 4. 2001-11-01. PMID:11557161. |
evaluation of dopamine d-2 receptor occupancy by clozapine, risperidone, and haloperidol in vivo in the rodent and nonhuman primate brain using 18f-fallypride. |
2001-11-01 |
2023-08-12 |
monkey |
| J Mukherjee, B T Christian, T K Narayanan, B Shi, J Manti. Evaluation of dopamine D-2 receptor occupancy by clozapine, risperidone, and haloperidol in vivo in the rodent and nonhuman primate brain using 18F-fallypride. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 4. 2001-11-01. PMID:11557161. |
we have used the high-affinity dopamine d-2 receptor radioligand, 18f-fallypride for evaluating receptor occupancy by the antipsychotic drugs, clozapine, risperidone, and haloperidol in rodents and nonhuman primates. |
2001-11-01 |
2023-08-12 |
monkey |
| J Mukherjee, B T Christian, T K Narayanan, B Shi, J Manti. Evaluation of dopamine D-2 receptor occupancy by clozapine, risperidone, and haloperidol in vivo in the rodent and nonhuman primate brain using 18F-fallypride. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 4. 2001-11-01. PMID:11557161. |
at therapeutically relevant doses, clozapine, risperidone, and haloperidol were able to compete significantly with the binding of 18f-fallypride in all brain regions in rhesus monkeys, and our analyses indicate that these drugs (clozapine, risperidone, and haloperidol) do not discriminate between the striatal (caudate and putamen) and the extrastriatal (thalamus and cortical regions) dopamine receptors. |
2001-11-01 |
2023-08-12 |
monkey |
| S Kähkönen, J Ahveninen, I P Jääskeläinen, S Kaakkola, R Näätänen, J Huttunen, E Pekkone. Effects of haloperidol on selective attention: a combined whole-head MEG and high-resolution EEG study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 4. 2001-11-01. PMID:11557163. |
a single dose of dopamine d2 receptor antagonist haloperidol (2 mg) or placebo was given orally to 12 right-handed healthy volunteers 3 hours before measurement. |
2001-11-01 |
2023-08-12 |
human |
| S Kähkönen, J Ahveninen, I P Jääskeläinen, S Kaakkola, R Näätänen, J Huttunen, E Pekkone. Effects of haloperidol on selective attention: a combined whole-head MEG and high-resolution EEG study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 4. 2001-11-01. PMID:11557163. |
taken together, haloperidol seemed to induce functional changes in neural networks accounting for both selective and involuntary attention, suggesting modulation of these functions by dopamine d2 receptors. |
2001-11-01 |
2023-08-12 |
human |
| A Ouagazzal, A J Grottick, J Moreau, G A Higgin. Effect of LSD on prepulse inhibition and spontaneous behavior in the rat. A pharmacological analysis and comparison between two rat strains. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 4. 2001-11-01. PMID:11557170. |
the dopamine da(2like) receptor antagonist, haloperidol (0.1 and 0.2 mg/kg, s.c.), was without effect against an lsd-induced disruption of ppi. |
2001-11-01 |
2023-08-12 |
rat |
| B Weber, E Schlicker, P Sokoloff, H Star. Identification of the dopamine autoreceptor in the guinea-pig retina as D(2) receptor using novel subtype-selective antagonists. British journal of pharmacology. vol 133. issue 8. 2001-10-25. PMID:11498509. |
the aim of the present study was to determine the receptor subtype (d(2) vs d(3)) involved in the inhibition of dopamine release in guinea-pig retinal discs, using established (haloperidol, (s)-nafadotride) and novel dopamine receptor antagonists (st-148, st-198). |
2001-10-25 |
2023-08-12 |
human |
| M El Yacoubi, C Ledent, M Parmentier, R Bertorelli, E Ongini, J Costentin, J M Vaugeoi. Adenosine A2A receptor antagonists are potential antidepressants: evidence based on pharmacology and A2A receptor knockout mice. British journal of pharmacology. vol 134. issue 1. 2001-10-11. PMID:11522598. |
administration of the dopamine d2 receptor antagonist haloperidol (50 - 200 microg kg(-1) i.p.) |
2001-10-11 |
2023-08-12 |
mouse |
| P J Pauwels, S Tardif, T Wurch, F C Colpaer. Real-time analysis of dopamine: antagonist interactions at recombinant human D2long receptor upon modulation of its activation state. British journal of pharmacology. vol 134. issue 1. 2001-10-11. PMID:11522600. |
dopamine antagonists were unable to block the transient high-magnitude ca(2+) phase at the wild-type d2long receptor upon simultaneous exposure to antagonist and dopamine, while full blockade of the low-magnitude ca(2+) phase did occur at a later time (onset-time: haloperidol < bromerguride < (+)-butaclamol). |
2001-10-11 |
2023-08-12 |
human |