| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M A Persinger, R P O'Connor, Y R Bureau, G H Parker, O Peredery, M Zegi. Synergistic induction of severe hypothermia (poikilothermia) by limbic seizures, acepromazine and physical restraint: role of noradrenergic alpha-1 receptors. Pharmacology, biochemistry, and behavior. vol 70. issue 2-3. 2002-02-05. PMID:11701206. |
administration of the specific and nonspecific dopamine antagonists haloperidol, chlorpromazine, sch23390, or clozapine did not simulate the effect at clinically effective dosages. |
2002-02-05 |
2023-08-12 |
rat |
| C A Heidbreder, R Foxton, J Cilia, Z A Hughes, A J Shah, A Atkins, A J Hunter, J J Hagan, D N Jone. Increased responsiveness of dopamine to atypical, but not typical antipsychotics in the medial prefrontal cortex of rats reared in isolation. Psychopharmacology. vol 156. issue 2-3. 2002-01-28. PMID:11549234. |
the present series of experiments sought to investigate the effect of clozapine (5-10 mg/kg s.c.), olanzapine (5 mg/kg s.c.), and haloperidol (0.5 mg/kg s.c.) on dopamine (da) and amino acids in the prelimbic/infralimbic subregion of the mpfc in group- and isolation-reared rats. |
2002-01-28 |
2023-08-12 |
rat |
| C Belzung, A M Le Guisquet, S Barreau, F Calatayu. An investigation of the mechanisms responsible for acute fluoxetine-induced anxiogenic-like effects in mice. Behavioural pharmacology. vol 12. issue 3. 2002-01-25. PMID:11485052. |
the drugs used included the benzodiazepine diazepam, the 5-ht1a receptor partial agonist buspirone, the 5-ht1a receptor antagonists pindolol and way-100635, the non-selective 5-ht2 receptor antagonists methiothepin, mianserin and ritanserin, the non-selective dopamine (da) receptor antagonist haloperidol, the d1 antagonist sch23390, the selective d2 antagonist raclopride, the d2/3 agonist quinelorane, the cholecystokininb (cck(b)) receptor antagonist ly 288513, and the corticotropin-releasing factor1 (crf1) receptor antagonist cp-154,526. |
2002-01-25 |
2023-08-12 |
mouse |
| M Levite, Y Chowers, Y Ganor, M Besser, R Hershkovits, L Cahalo. Dopamine interacts directly with its D3 and D2 receptors on normal human T cells, and activates beta1 integrin function. European journal of immunology. vol 31. issue 12. 2002-01-24. PMID:11745370. |
the dopamine receptor agonists bromocriptine and pergolide mimic the direct effect of dopamine on the beta1 integrin function, while the dopamine receptor antagonists butaclamol and haloperidol suppress it, suggesting additional signaling via the dopamine d2 receptor subtype. |
2002-01-24 |
2023-08-12 |
human |
| M P Castelli, I Mocci, A M Sanna, G L Gessa, L Pan. (-)S amisulpride binds with high affinity to cloned dopamine D(3) and D(2) receptors. European journal of pharmacology. vol 432. issue 2-3. 2002-01-16. PMID:11740949. |
the interaction of racemic (+/-)rs amisulpride and its two enantiomers (+)r and (-)s with dopamine d(2) and dopamine d(3) receptors subtypes were compared with that of haloperidol. |
2002-01-16 |
2023-08-12 |
human |
| M P Castelli, I Mocci, A M Sanna, G L Gessa, L Pan. (-)S amisulpride binds with high affinity to cloned dopamine D(3) and D(2) receptors. European journal of pharmacology. vol 432. issue 2-3. 2002-01-16. PMID:11740949. |
both racemic and the (-)s enantiomer exhibited 2-4 ([3h]spiperone)- and 3-4 ([3h]nemonapride)-fold higher affinity than haloperidol for dopamine rd(3) receptor, respectively. |
2002-01-16 |
2023-08-12 |
human |
| M P Castelli, I Mocci, A M Sanna, G L Gessa, L Pan. (-)S amisulpride binds with high affinity to cloned dopamine D(3) and D(2) receptors. European journal of pharmacology. vol 432. issue 2-3. 2002-01-16. PMID:11740949. |
the (+)r enantiomer has weaker affinity with respect to haloperidol for both dopamine hd(2l) and dopamine rd(3) receptors. |
2002-01-16 |
2023-08-12 |
human |
| H Miwa, T Fuwa, K Nishi, T Kond. Subthalamo-pallido-striatal axis: a feedback system in the basal ganglia. Neuroreport. vol 12. issue 17. 2002-01-11. PMID:11726797. |
systemic administration of a dopamine d2 receptor blocker, haloperidol, but not vehicle, significantly increased the number of c-fos-immunoreactive neurons in the globus pallidus (gp) in rats. |
2002-01-11 |
2023-08-12 |
rat |
| M Markianos, L Lykouras, G Moussas, J Hatzimanoli. Changes in dopamine receptor responsivity during alcohol detoxification may predict relapse. Drug and alcohol dependence. vol 64. issue 3. 2002-01-03. PMID:11672950. |
the patients had been tested earlier during their usual alcohol consumption and immediately after detoxification for the responsivity of d2 dopamine receptors (as measured by the increases in prolactin plasma levels caused by intramuscular administration of 5 mg of the dopamine receptor blocker haloperidol). |
2002-01-03 |
2023-08-12 |
human |
| M Boules, B McMahon, L Warrington, J Stewart, J Jackson, A Fauq, D McCormick, E Richelso. Neurotensin analog selective for hypothermia over antinociception and exhibiting atypical neuroleptic-like properties. Brain research. vol 919. issue 1. 2002-01-03. PMID:11689157. |
in studies using in vivo microdialysis nt77l showed similar effects on dopamine turnover to those of clozapine, and significantly different from those of haloperidol in the striatum. |
2002-01-03 |
2023-08-12 |
rat |
| Y Adachi, H Wada, H Higuchi, K Watanabe, T Sato. [The effect of halothane anesthesia on dopamine release induced by apomorphine or haloperidol--an in vivo microdialysis study in rats striatum]. Masui. The Japanese journal of anesthesiology. vol 50. issue 10. 2001-12-28. PMID:11712340. |
[the effect of halothane anesthesia on dopamine release induced by apomorphine or haloperidol--an in vivo microdialysis study in rats striatum]. |
2001-12-28 |
2023-08-12 |
rat |
| A Berlin. Effects of haloperidol and phentolamine on the crustacean cardiac ganglion. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 130. issue 1. 2001-12-17. PMID:11544145. |
haloperidol (a dopamine d2 blocker in vertebrates) and phentolamine (an alpha-adrenergic blocker) alter the pattern of bursting by the isolated cardiac ganglion of the lobster when perfused at concentrations of 10(-6)-10(-5) mol/l. |
2001-12-17 |
2023-08-12 |
lobster |
| S Kähkönen, J Ahveninen, E Pekkonen, S Kaakkola, J Huttunen, T Peltonen, R J Ilmoniemi, I P Jääskeläine. No evidence for dependence of early cortical auditory processing on dopamine D(2)-receptor modulation: a whole-head magnetoencephalographic study. Psychiatry research. vol 107. issue 2. 2001-12-07. PMID:11530277. |
in a double-blind, randomized, placebo-controlled, cross-over design study, the dopamine d(2) receptor antagonist haloperidol (2 mg) was given orally to 12 healthy volunteers. |
2001-12-07 |
2023-08-12 |
human |
| P L Vera, I Nadelhaf. Effects of the atypical neuroleptic clozapine on micturition parameters in anesthetized rats. Neurourology and urodynamics. vol 20. issue 5. 2001-12-04. PMID:11574938. |
since both clozapine and haloperidol have interactions with other transmitter systems beside dopamine, we suggest that central antagonism of d2 receptors, coupled to central antagonism of another receptor system and peripheral muscarinic receptor blockade, may account for clozapine's potent effects on micturition. |
2001-12-04 |
2023-08-12 |
rat |
| K J Stanhope, N R Mirza, M J Bickerdike, J L Bright, N R Harrington, M B Hesselink, G A Kennett, S Lightowler, M J Sheardown, R Syed, R L Upton, G Wadsworth, S M Weiss, A Wyat. The muscarinic receptor agonist xanomeline has an antipsychotic-like profile in the rat. The Journal of pharmacology and experimental therapeutics. vol 299. issue 2. 2001-12-04. PMID:11602695. |
finally, haloperidol, clozapine, pilocarpine, and xanomeline, all induced an increase in dopamine turnover in medial prefrontal cortex. |
2001-12-04 |
2023-08-12 |
rat |
| T Hirayama, T Kita, Y Ogawa, H Ohsawa, M Yamashita, T Nakashima, T Kishimot. Effect of chronic treatment with haloperidol on vasopressin release and behavioral changes by osmotic stimulation of the supraoptic nucleus. Life sciences. vol 69. issue 18. 2001-12-04. PMID:11669458. |
to investigate the relationship between dopamine d2 blockers and these syndromes, we designed a behavioral and neurochemical study using hyperosmotic stimulation in the supraoptic nucleus (son) by microdialysis after chronic treatment with haloperidol in rats. |
2001-12-04 |
2023-08-12 |
rat |
| J Mukherjee, B T Christian, T K Narayanan, B Shi, J Manti. Evaluation of dopamine D-2 receptor occupancy by clozapine, risperidone, and haloperidol in vivo in the rodent and nonhuman primate brain using 18F-fallypride. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 4. 2001-11-01. PMID:11557161. |
evaluation of dopamine d-2 receptor occupancy by clozapine, risperidone, and haloperidol in vivo in the rodent and nonhuman primate brain using 18f-fallypride. |
2001-11-01 |
2023-08-12 |
monkey |
| J Mukherjee, B T Christian, T K Narayanan, B Shi, J Manti. Evaluation of dopamine D-2 receptor occupancy by clozapine, risperidone, and haloperidol in vivo in the rodent and nonhuman primate brain using 18F-fallypride. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 4. 2001-11-01. PMID:11557161. |
we have used the high-affinity dopamine d-2 receptor radioligand, 18f-fallypride for evaluating receptor occupancy by the antipsychotic drugs, clozapine, risperidone, and haloperidol in rodents and nonhuman primates. |
2001-11-01 |
2023-08-12 |
monkey |
| J Mukherjee, B T Christian, T K Narayanan, B Shi, J Manti. Evaluation of dopamine D-2 receptor occupancy by clozapine, risperidone, and haloperidol in vivo in the rodent and nonhuman primate brain using 18F-fallypride. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 4. 2001-11-01. PMID:11557161. |
at therapeutically relevant doses, clozapine, risperidone, and haloperidol were able to compete significantly with the binding of 18f-fallypride in all brain regions in rhesus monkeys, and our analyses indicate that these drugs (clozapine, risperidone, and haloperidol) do not discriminate between the striatal (caudate and putamen) and the extrastriatal (thalamus and cortical regions) dopamine receptors. |
2001-11-01 |
2023-08-12 |
monkey |
| S Kähkönen, J Ahveninen, I P Jääskeläinen, S Kaakkola, R Näätänen, J Huttunen, E Pekkone. Effects of haloperidol on selective attention: a combined whole-head MEG and high-resolution EEG study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 4. 2001-11-01. PMID:11557163. |
a single dose of dopamine d2 receptor antagonist haloperidol (2 mg) or placebo was given orally to 12 right-handed healthy volunteers 3 hours before measurement. |
2001-11-01 |
2023-08-12 |
human |