| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miriam Schneider, Michael Koc. Chronic pubertal, but not adult chronic cannabinoid treatment impairs sensorimotor gating, recognition memory, and the performance in a progressive ratio task in adult rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 10. 2003-12-05. PMID:12888772. |
this long-lasting ppi deficit was reversed by the acute administration of the dopamine antagonist haloperidol. |
2003-12-05 |
2023-08-12 |
rat |
| Krisztina Gál, István Gyertyá. Targeting the dopamine D3 receptor cannot influence continuous reinforcement cocaine self-administration in rats. Brain research bulletin. vol 61. issue 6. 2003-12-05. PMID:14519456. |
both the dopamine d1 selective sch-23390 (0.2, 0.1 mg/kg) and the dopamine d2 receptor preferring haloperidol (0.5, 0.2 mg/kg) increased the lever-pressing. |
2003-12-05 |
2023-08-12 |
rat |
| Lidia Devoino, Margarita Cheido, Elizaveta Alperina, Galina Idov. Evidence for a role of dopaminergic mechanisms in the immunostimulating effect of mu-opioid receptor agonist DAGO. The International journal of neuroscience. vol 113. issue 10. 2003-12-05. PMID:14534037. |
the present study demonstrates that: (1) activation of micro -opioid receptors by systemic administration of a highly selective agonist dago (100 microg/kg) results in a significant increase in the number of plaque- and rosette-forming cells in the spleen of cba mice as well as wistar rats on the 5th day following sheep red blood cells (5 x 10(8)) immunization, (2) the immunostimulatory effect of dago is mediated by central mechanisms including the hypothalamus-hypophysis complex; (3) the postsynaptic dopamine (da) receptors of d2 type are involved in the dago-induced immunostimulation since the combined treatment of animals with haloperidol (2 mg/kg), a blocker of da d2 receptors, and dago abolished this effect; (4) the nuclei caudatus and accumbens of the nigrostriatal and mesolimbic daergic systems, respectively, are implicated in the immune response stimulation caused by dago. |
2003-12-05 |
2023-08-12 |
mouse |
| M Gruss, J Bock, K Brau. Haloperidol impairs auditory filial imprinting and modulates monoaminergic neurotransmission in an imprinting-relevant forebrain area of the domestic chick. Journal of neurochemistry. vol 87. issue 3. 2003-11-24. PMID:14535951. |
the results revealed that: (i) the systemic application of the potent dopamine receptor antagonist haloperidol (7.5 mg/kg) strongly impairs auditory filial imprinting; (ii) systemic haloperidol induces a tetrodotoxin-sensitive increase of extracellular levels of the dopamine metabolite, homovanillic acid, in the mnh, whereas the levels of glutamate, taurine and the serotonin metabolite, 5-hydroxyindole-3-acetic acid, remain unchanged; (iii) haloperidol (0.01, 0.1, 1 mm) infused locally into the mnh increases glutamate, taurine and 5- hydroxyindole-3-acetic acid levels in a dose-dependent manner, whereas homovanillic acid levels remain unchanged; (iv) systemic haloperidol infusion reinforces the n-methyl-d-aspartate receptor-mediated inhibitory modulation of the dopaminergic neurotransmission within the mnh. |
2003-11-24 |
2023-08-12 |
chicken |
| Takahiro Nakazawa, Takaaki Yasuda, Joji Ueda, Keisuke Ohsaw. Antidepressant-like effects of apigenin and 2,4,5-trimethoxycinnamic acid from Perilla frutescens in the forced swimming test. Biological & pharmaceutical bulletin. vol 26. issue 4. 2003-11-21. PMID:12673028. |
furthermore, intraperitoneal administration of haloperidol (0.2 mg/kg), a dopamine d(2) antagonist, blocked the apigenin (25 mg/kg)-induced decrease in immobility in the forced swimming test. |
2003-11-21 |
2023-08-12 |
mouse |
| E Bujdosó, M Jászberényi, J Farkas, G Tóth, M Wollemann, G Telegd. Behavioral and neuroendocrine actions of the Met-enkephalin-related peptide MERF. Hormones and behavior. vol 43. issue 2. 2003-11-19. PMID:12694640. |
the dopamine antagonist haloperidol and a corticotropin-releasing hormone (crh) antagonist were also preadministered to shed light on the transmission of the actions of merf. |
2003-11-19 |
2023-08-12 |
mouse |
| Wendy H Fasulo, Scott E Hemb. Time-dependent changes in gene expression profiles of midbrain dopamine neurons following haloperidol administration. Journal of neurochemistry. vol 87. issue 1. 2003-11-12. PMID:12969267. |
time-dependent changes in gene expression profiles of midbrain dopamine neurons following haloperidol administration. |
2003-11-12 |
2023-08-12 |
Not clear |
| Richard I Dafters, Stephany M Biell. The effect of 3,4-methylenedioxymethamphetamine ('Ecstasy') on serotonergic regulation of the mammalian circadian clock mechanism in rats: the role of dopamine and hyperthermia. Neuroscience letters. vol 350. issue 2. 2003-11-06. PMID:12972167. |
since dopamine release has been implicated in the serotonergic neurotoxicity, we examined the effects of the dopamine synthesis inhibitor alpha-methyl-p-tyrosine (ampt) and the d2 receptor antagonist haloperidol (hal) on the long-term effect of mdma on serotonergic regulation of the scn neuronal firing rhythm. |
2003-11-06 |
2023-08-12 |
rat |
| Barbara K Lipska, Daniel N Lerman, Zin Z Khaing, Cynthia Shannon Weickert, Daniel R Weinberge. Gene expression in dopamine and GABA systems in an animal model of schizophrenia: effects of antipsychotic drugs. The European journal of neuroscience. vol 18. issue 2. 2003-09-24. PMID:12887421. |
we used in situ hybridization histochemistry to assess expression of dopamine receptors (d1r, d2r and d3r), neurotensin, proenkephalin and glutamate decarboxylase-67 (gad67) in the prefrontal cortex, striatum, and/or nucleus accumbens in adult rats with neonatal ventral hippocampal (vh) lesions and in control animals after acute and chronic treatment with antipsychotic drugs clozapine and haloperidol. |
2003-09-24 |
2023-08-12 |
rat |
| W S Cobb, E D Abercrombi. Relative involvement of globus pallidus and subthalamic nucleus in the regulation of somatodendritic dopamine release in substantia nigra is dopamine-dependent. Neuroscience. vol 119. issue 3. 2003-09-12. PMID:12809698. |
in contrast, acute blockade of dopamine receptors by systemic haloperidol administration produced an increase in somatodendritic dopamine release in substantia nigra that was found to be dependent exclusively upon activation of nigral glutamate receptors. |
2003-09-12 |
2023-08-12 |
Not clear |
| W S Cobb, E D Abercrombi. Relative involvement of globus pallidus and subthalamic nucleus in the regulation of somatodendritic dopamine release in substantia nigra is dopamine-dependent. Neuroscience. vol 119. issue 3. 2003-09-12. PMID:12809698. |
the effects of these manipulations on spontaneous efflux of somatodendritic dopamine and on increases in this measure produced by systemic haloperidol administration were determined in ipsilateral substantia nigra using in vivo microdialysis. |
2003-09-12 |
2023-08-12 |
Not clear |
| W S Cobb, E D Abercrombi. Relative involvement of globus pallidus and subthalamic nucleus in the regulation of somatodendritic dopamine release in substantia nigra is dopamine-dependent. Neuroscience. vol 119. issue 3. 2003-09-12. PMID:12809698. |
when haloperidol was administered systemically in conjunction with microinfusion of muscimol into globus pallidus, an increase in nigral dopamine efflux was observed that was significantly greater than that which was produced singly by muscimol microinfusion into globus pallidus or by systemic haloperidol administration. |
2003-09-12 |
2023-08-12 |
Not clear |
| W S Cobb, E D Abercrombi. Relative involvement of globus pallidus and subthalamic nucleus in the regulation of somatodendritic dopamine release in substantia nigra is dopamine-dependent. Neuroscience. vol 119. issue 3. 2003-09-12. PMID:12809698. |
muscimol application into subthalamic nucleus, however, completely abolished the stimulatory effect of systemic haloperidol on dendritic dopamine efflux in substantia nigra. |
2003-09-12 |
2023-08-12 |
Not clear |
| W S Cobb, E D Abercrombi. Relative involvement of globus pallidus and subthalamic nucleus in the regulation of somatodendritic dopamine release in substantia nigra is dopamine-dependent. Neuroscience. vol 119. issue 3. 2003-09-12. PMID:12809698. |
the present data extend our previous findings by demonstrating: 1) an important involvement of globus pallidus efferents in the gabaergic regulation of somatodendritic dopamine efflux in substantia nigra under normal conditions and, 2) an emergent predominant role of subthalamic nucleus efferents in the glutamate-dependent increase in somatodendritic dopamine efflux observed after systemic haloperidol administration. |
2003-09-12 |
2023-08-12 |
Not clear |
| Kiichi Ishiwata, Kazunori Kawamura, Tadayuki Kobayashi, Kiyoshi Matsun. Sigma1 and dopamine D2 receptor occupancy in the mouse brain after a single administration of haloperidol and two dopamine D2-like receptor ligands. Nuclear medicine and biology. vol 30. issue 4. 2003-09-09. PMID:12767400. |
sigma1 and dopamine d2 receptor occupancy in the mouse brain after a single administration of haloperidol and two dopamine d2-like receptor ligands. |
2003-09-09 |
2023-08-12 |
mouse |
| Kiichi Ishiwata, Kazunori Kawamura, Tadayuki Kobayashi, Kiyoshi Matsun. Sigma1 and dopamine D2 receptor occupancy in the mouse brain after a single administration of haloperidol and two dopamine D2-like receptor ligands. Nuclear medicine and biology. vol 30. issue 4. 2003-09-09. PMID:12767400. |
we investigated sigma(1) and dopamine d(2) receptor occupancy in mouse brain after a single injection of haloperidol, nemonapride, or spiperone using [(11)c]sa4503 and [(11)c]raclopride, respectively. |
2003-09-09 |
2023-08-12 |
mouse |
| Jadwiga Wardas, Małgorzata Pietraszek, Marta Dziedzicka-Wasylewsk. SCH 58261, a selective adenosine A2A receptor antagonist, decreases the haloperidol-enhanced proenkephalin mRNA expression in the rat striatum. Brain research. vol 977. issue 2. 2003-09-02. PMID:12834887. |
the present results suggest that similarly to other a(2a) receptor antagonists, sch 58261 normalizes activity of the striopallidal pathway, enhanced by blockade of dopamine d(2) receptors with haloperidol, which may result in recovery of motor functions. |
2003-09-02 |
2023-08-12 |
rat |
| Laura Pozzi, Kerstin Håkansson, Alessandro Usiello, Anders Borgkvist, Maria Lindskog, Paul Greengard, Gilberto Fison. Opposite regulation by typical and atypical anti-psychotics of ERK1/2, CREB and Elk-1 phosphorylation in mouse dorsal striatum. Journal of neurochemistry. vol 86. issue 2. 2003-08-21. PMID:12871586. |
here, we have examined the effect of haloperidol and clozapine, two anti-psychotic drugs, and eticlopride, a selective dopamine d2 receptor antagonist, on the state of phosphorylation of erk1/2, creb and elk-1, in the mouse dorsal striatum. |
2003-08-21 |
2023-08-12 |
mouse |
| Carlos M Villalón, Eduardo Ramírez-San Juan, Araceli Sánchez-López, Guadalupe Bravo, Edwin W Willems, Pramod R Saxena, David Centurió. Pharmacological profile of the vascular responses to dopamine in the canine external carotid circulation. Pharmacology & toxicology. vol 92. issue 4. 2003-08-12. PMID:12753419. |
the vasoconstrictor response to dopamine was abolished after intravenous administration of the antagonists, phentolamine (alpha1/2; 2000 microg kg-1) or rauwolscine (alpha2; 100 microg kg-1), but remained unaffected after prazosin (alpha1; 100 microg kg-1) or haloperidol (d2-like; 1000 microg kg-1). |
2003-08-12 |
2023-08-12 |
Not clear |
| Carlos M Villalón, Eduardo Ramírez-San Juan, Araceli Sánchez-López, Guadalupe Bravo, Edwin W Willems, Pramod R Saxena, David Centurió. Pharmacological profile of the vascular responses to dopamine in the canine external carotid circulation. Pharmacology & toxicology. vol 92. issue 4. 2003-08-12. PMID:12753419. |
these vasodilator responses to dopamine remained unchanged after intravenous haloperidol or propranolol (1000 microg kg-1 each). |
2003-08-12 |
2023-08-12 |
Not clear |