| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kerstin Håkansson, Laura Pozzi, Alessandro Usiello, John Haycock, Emiliana Borrelli, Gilberto Fison. Regulation of striatal tyrosine hydroxylase phosphorylation by acute and chronic haloperidol. The European journal of neuroscience. vol 20. issue 4. 2004-10-14. PMID:15305880. |
here we show that the increases in th phosphorylation produced by haloperidol at ser31 and ser40, two sites critically involved in the regulation of enzymatic activity, are abolished in dopamine d2 receptor-null mice and mimicked by the selective dopamine d2 receptor antagonist, eticlopride. |
2004-10-14 |
2023-08-12 |
mouse |
| Kerstin Håkansson, Laura Pozzi, Alessandro Usiello, John Haycock, Emiliana Borrelli, Gilberto Fison. Regulation of striatal tyrosine hydroxylase phosphorylation by acute and chronic haloperidol. The European journal of neuroscience. vol 20. issue 4. 2004-10-14. PMID:15305880. |
these results provide a model accounting for the stimulation exerted by haloperidol on dopamine synthesis. |
2004-10-14 |
2023-08-12 |
mouse |
| Kerstin Håkansson, Laura Pozzi, Alessandro Usiello, John Haycock, Emiliana Borrelli, Gilberto Fison. Regulation of striatal tyrosine hydroxylase phosphorylation by acute and chronic haloperidol. The European journal of neuroscience. vol 20. issue 4. 2004-10-14. PMID:15305880. |
according to this model, haloperidol increases th activity via blockade of dopamine d2 receptors, disinhibition of dopaminergic projection neurons and erk1/2-dependent phosphorylation of th at ser31 and ser40. |
2004-10-14 |
2023-08-12 |
mouse |
| C Cavallotti, A Frati, D Cavallotti, F M Tranquilli Leal. Dopaminergic receptors in rat dura mater: pharmacological characteristics. Clinical and experimental pharmacology & physiology. vol 31. issue 3. 2004-10-07. PMID:15008964. |
the greater sensitivity to displacement by amisulpride, bromocryptine, domperidone, haloperidol, raclopride and l-sulpiride than to displacement by n-propyl-nor-apomorphine, quinpirole and clozapine suggests that the immunofluorescent sites observed in these experiments are likely to belong to the dopamine d2 receptor subtype. |
2004-10-07 |
2023-08-12 |
rat |
| Didier Cussac, Valérie Pasteau, Mark J Milla. Characterisation of Gs activation by dopamine D1 receptors using an antibody capture assay: antagonist properties of clozapine. European journal of pharmacology. vol 485. issue 1-3. 2004-10-05. PMID:14757130. |
employing this novel technique, the typical and atypical antipsychotics, clozapine and haloperidol, respectively, both exhibited antagonist properties at dopamine d1 receptors. |
2004-10-05 |
2023-08-12 |
human |
| V F Kichigin. [Dopaminergic regulation of theta activity of septohippocampal neuron in the awake rabbit]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 54. issue 2. 2004-10-05. PMID:15174266. |
the effects of dopamine reuptake blocker nomifensine and nonselective antagonist of dopamine receptors haloperidol on the theta rhythmicity of the medial septal neurons and hippocampal eeg were investigated in the rabbit. |
2004-10-05 |
2023-08-12 |
rabbit |
| Patrick J Zirnheld, Christine A Carroll, Paul D Kieffaber, Brian F O'Donnell, Anantha Shekhar, William P Hetric. Haloperidol impairs learning and error-related negativity in humans. Journal of cognitive neuroscience. vol 16. issue 6. 2004-09-27. PMID:15298795. |
we examined the role of dopamine in ern and behavioral indices of learning by administering either 3 mg of the dopamine antagonist (da) haloperidol (n = 17); 25 mg of diphenhydramine (n = 16), which has a similar cns profile but without da properties; or placebo (n = 18) in a randomized, double-blind manner to healthy volunteers. |
2004-09-27 |
2023-08-12 |
human |
| Robert B Moreland, Masaki Nakane, Diana L Donnelly-Roberts, Loan N Miller, Renjie Chang, Marie E Uchic, Marc A Terranova, Earl J Gubbins, Rosalind J Helfrich, Marian T Namovic, Odile F El-Kouhen, Jeffrey N Masters, Jorge D Brion. Comparative pharmacology of human dopamine D(2)-like receptor stable cell lines coupled to calcium flux through Galpha(qo5). Biochemical pharmacology. vol 68. issue 4. 2004-09-08. PMID:15276084. |
other d(2)-like antagonists, haloperidol, clozapine, and domperidone showed concentration-dependent inhibition of dopamine responses at all three receptors with k(i) ranging from 0.05 to 48.3 nm. |
2004-09-08 |
2023-08-12 |
human |
| Satoshi Yanahashi, Kenji Hashimoto, Kotaro Hattori, Shigeki Yuasa, Masaomi Iy. Role of NMDA receptor subtypes in the induction of catalepsy and increase in Fos protein expression after administration of haloperidol. Brain research. vol 1011. issue 1. 2004-08-23. PMID:15140647. |
the increase of fos expression in the striatum induced by haloperidol, an antagonist of the dopamine d2 receptor, might be related to the activation of glutamatergic neurotransmission, especially that of n-methyl-d-aspartate (nmda) receptors. |
2004-08-23 |
2023-08-12 |
mouse |
| Robert E McCullumsmith, Todd L Stincic, Smriti M Agrawal, James H Meador-Woodruf. Differential effects of antipsychotics on haloperidol-induced vacuous chewing movements and subcortical gene expression in the rat. European journal of pharmacology. vol 477. issue 2. 2004-08-11. PMID:14519413. |
thus, we treated rats with haloperidol-decanoate for 12 weeks, and assessed the effects of additional treatment with olanzapine, haloperidol, clozapine, or vehicle on vacuous chewing movements and expression of transcripts for dopamine receptors, tyrosine hydroxylase, delta-opioid receptor, prodynorphin, preproenkephalin, glutamic acid decarboxylase-65 (glutamic acid decarboxylase (gad)-65) and gad-67 and n-methyl-d-aspartate (nmda) receptor subunits in the striatum and its efferent pathways. |
2004-08-11 |
2023-08-12 |
rat |
| J Carretero, E Weruaga, E Hernández, D Burks, J M Riesco, M Rubio, J G Briñón, J Aijón, R Vázquez, J R Alons. Dopaminergic modulation of nNOS expression in the pituitary gland of male rat. Anatomy and embryology. vol 207. issue 4-5. 2004-08-10. PMID:14618399. |
therefore, we examined the effects of intraventricular administration of the dopamine antagonist haloperidol (40 microg) on the pituitary expression of neuronal nitric oxide synthase (nnos) in male adult rats. |
2004-08-10 |
2023-08-12 |
rat |
| Akihiro Takano, Tetsuya Suhara, Jun Maeda, Kiyoshi Ando, Takashi Okauchi, Shigeru Obayashi, Takashi Nakayama, Shitij Kapu. Relation between cortical dopamine D(2) receptor occupancy and suppression of conditioned avoidance response in non-human primate. Psychiatry and clinical neurosciences. vol 58. issue 3. 2004-07-27. PMID:15149302. |
the purpose of the present paper was to investigate the relationship between cortical dopamine d(2) receptor occupancy and the suppression of car by haloperidol in non-human primate. |
2004-07-27 |
2023-08-12 |
monkey |
| Margaret E Hamilton, Arthur S Freema. Diet and chronic haloperidol effects on rat midbrain dopamine neurons. Synapse (New York, N.Y.). vol 53. issue 1. 2004-07-16. PMID:15150734. |
diet and chronic haloperidol effects on rat midbrain dopamine neurons. |
2004-07-16 |
2023-08-12 |
rat |
| Mark J Millan, Didier Cussac, Alain Gobert, Françoise Lejeune, Jean-Michel Rivet, Clotilde Mannoury La Cour, Adrian Newman-Tancredi, Jean-Louis Peglio. S32504, a novel naphtoxazine agonist at dopamine D3/D2 receptors: I. Cellular, electrophysiological, and neurochemical profile in comparison with ropinirole. The Journal of pharmacology and experimental therapeutics. vol 309. issue 3. 2004-07-01. PMID:14978194. |
correspondingly, s32504 (0.0025-0.63 mg/kg, s.c.) potently reduced dialysis levels (and synthesis) of dopamine in striatum, nucleus accumbens, and frontal cortex of freely moving rats, actions blocked by haloperidol and l741,626 but not by s33084. |
2004-07-01 |
2023-08-12 |
human |
| Yurie Akimoto, Takahiro Horinouchi, Yoshio Tanaka, Katsuo Koik. The beta3-adrenoceptor-mediated relaxation induced by dopamine in guinea pig taenia caecum. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi. vol 39. issue 3. 2004-06-02. PMID:14572171. |
atenolol (3 x 10(-7)-3 x 10(-4) m), butoxamine (10(-7)-10(-4) m), prazosin (10(-8)-10(-5) m), yohimbine (10(-8)-10(-5) m), sch 23390 (10(-8)-10(-5) m) and haloperidol (10(-8)-10(-5) m) had no effect on the potency of dopamine. |
2004-06-02 |
2023-08-12 |
Not clear |
| Maria A Aguilar, Jose Miñarro, Vicente M Simó. Morphine potentiates the impairing effects of neuroleptics on two-way active conditioned avoidance response in male mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 28. issue 2. 2004-05-28. PMID:14751417. |
the effects of morphine (12.6 mg/kg), haloperidol (0.075 mg/kg), sulpiride (20 mg/kg) and risperidone (0.1 mg/kg) alone as well as morphine combined with these dopamine (da) antagonists on the acquisition and performance of the car were explored in mice. |
2004-05-28 |
2023-08-12 |
mouse |
| Laura Dazzi, Emanuele Seu, Giulia Cherchi, Giovanni Biggi. Inhibition of stress-induced dopamine output in the rat prefrontal cortex by chronic treatment with olanzapine. Biological psychiatry. vol 55. issue 5. 2004-05-27. PMID:15023575. |
the effects of olanzapine and clozapine on the stress-induced increase in dopamine output in the rat cerebral cortex have now been compared with that of haloperidol. |
2004-05-27 |
2023-08-12 |
rat |
| N B Gamaleia, T I Kuz'mina, O A Shostak, A A Gamaleia, I G Dmitriev. [Method for determining dopamine and morphine binding sites in lymphocytes from human peripheral blood]. Klinicheskaia laboratornaia diagnostika. issue 12. 2004-05-24. PMID:14971325. |
the binding of peroxidase-marked ligands of dopamine and mu-opioid receptors with lymphocytes was oppressed by the dose-dependant preliminary incubation with antagonists (haloperidol, naloxone), on the basis of which the presence of the ligand-receptor interaction can be suggested. |
2004-05-24 |
2023-08-12 |
human |
| Juan Ji An, Sang-Rae Cho, Dae Won Jeong, Kye Won Park, Young Soo Ahn, Ja-Hyun Bai. Anti-proliferative effects and cell death mediated by two isoforms of dopamine D2 receptors in pituitary tumor cells. Molecular and cellular endocrinology. vol 206. issue 1-2. 2004-05-21. PMID:12943989. |
dopamine-induced cell death was observed in the gh3d2l and gh3d2s cells, and was accompanied by dna laddering and caspase-3 activation, which were blunted by haloperidol, indicating that dopamine-induced cell death in these cells is mediated by the dopamine d2 receptors. |
2004-05-21 |
2023-08-12 |
rat |
| Juan Ji An, Sang-Rae Cho, Dae Won Jeong, Kye Won Park, Young Soo Ahn, Ja-Hyun Bai. Anti-proliferative effects and cell death mediated by two isoforms of dopamine D2 receptors in pituitary tumor cells. Molecular and cellular endocrinology. vol 206. issue 1-2. 2004-05-21. PMID:12943989. |
it was further shown that p38 mapk and erk activation was inhibited by the antioxidant, n-acetylcysteine (nac), and that a treatment with haloperidol completely blocked the p38 and erk activation induced by dopamine. |
2004-05-21 |
2023-08-12 |
rat |