| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Vriend, Lisa Drege. Effects of haloperidol and melatonin on the in situ activity of nigrostriatal tyrosine hydroxylase in male Syrian hamsters. Life sciences. vol 78. issue 15. 2006-03-31. PMID:16263138. |
after receiving daily ip injections (1.25 mg/kg ip) of haloperidol for 21 days, the animals were sacrificed and brain tissue collected for analysis of dopamine and metabolites by hplc with electrochemical detection. |
2006-03-31 |
2023-08-12 |
Not clear |
| J Vriend, Lisa Drege. Effects of haloperidol and melatonin on the in situ activity of nigrostriatal tyrosine hydroxylase in male Syrian hamsters. Life sciences. vol 78. issue 15. 2006-03-31. PMID:16263138. |
tissue content of dopamine and its metabolites, dopac and hva, was depressed in striatum of animals receiving haloperidol, and tyrosine hydroxylase (th) activity was significantly decreased 20-24 h after the last injection (from 1823 +/- 63 to 1139 +/- 85 pg l-dopa/mg tissue). |
2006-03-31 |
2023-08-12 |
Not clear |
| A Khan, F Batool, D J Halee. Behavioral effects of 8-OH-DPAT in single and repeated haloperidol injected rats. Pakistan journal of pharmaceutical sciences. vol 14. issue 2. 2006-03-01. PMID:16414856. |
the present study was designed to examine the modulatory effect of serotonergic activities on haloperidol induced up-regulation of dopamine d2 receptors. |
2006-03-01 |
2023-08-12 |
rat |
| Erum Shireen, Qurrat-ul-Ain, Farhat Batool, Z S Saify, Darakhshan J Halee. Neurochemical effects of 8-hydroxy-2-di-n-propylamino tetralin in rats treated with haloperidol. Pakistan journal of pharmaceutical sciences. vol 15. issue 1. 2006-03-01. PMID:16414870. |
haloperidol plus 8-oh-dpat injected animals exhibited a decrease in dopamine (da) and an increase in da metabolite homovanillic acid (hva) levels in the striatum and rest of the brain. |
2006-03-01 |
2023-08-12 |
rat |
| Sheila V Stager, Karim Calis, Dale Grothe, Meir Bloch, Nannette M Berensen, Paul J Smith, Allen Brau. Treatment with medications affecting dopaminergic and serotonergic mechanisms: effects on fluency and anxiety in persons who stutter. Journal of fluency disorders. vol 30. issue 4. 2006-02-28. PMID:16246409. |
medications with dopamine antagonist properties, such as haloperidol, and those with serotonin reuptake inhibitor properties, such as clomipramine, have been shown to improve fluency. |
2006-02-28 |
2023-08-12 |
human |
| Obaid Ali, Darakshan J Haleem, Roohi Obaid, Noor Kamil, Mohammed A Haleem, Syed Waseemuddin Ahme. Effect of co administration of haloperidol and large neutral amino acids (tryptophan and valine) on rats striatal dopamine, serotonin and their metabolism. Pakistan journal of pharmaceutical sciences. vol 16. issue 1. 2006-02-27. PMID:16414563. |
effect of co administration of haloperidol and large neutral amino acids (tryptophan and valine) on rats striatal dopamine, serotonin and their metabolism. |
2006-02-27 |
2023-08-12 |
rat |
| Kerstin Håkansson, Stacey Galdi, Joseph Hendrick, Gretchen Snyder, Paul Greengard, Gilberto Fison. Regulation of phosphorylation of the GluR1 AMPA receptor by dopamine D2 receptors. Journal of neurochemistry. vol 96. issue 2. 2006-02-17. PMID:16336634. |
administration of haloperidol, an antipsychotic drug with dopamine d2 receptor antagonistic properties, increases the phosphorylation of glur1 at ser845, without affecting phosphorylation at ser831. |
2006-02-17 |
2023-08-12 |
mouse |
| Tod E Kippin, Shitij Kapur, Derek van der Koo. Dopamine specifically inhibits forebrain neural stem cell proliferation, suggesting a novel effect of antipsychotic drugs. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 24. 2006-02-14. PMID:15958748. |
the increase in nscs by haloperidol is dependent on central dopamine d2 receptors, and these receptors are expressed by nscs. |
2006-02-14 |
2023-08-12 |
rat |
| Tod E Kippin, Shitij Kapur, Derek van der Koo. Dopamine specifically inhibits forebrain neural stem cell proliferation, suggesting a novel effect of antipsychotic drugs. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 24. 2006-02-14. PMID:15958748. |
thus, haloperidol increases adult mammalian brain proliferation by antagonizing dopamine at d2 receptors on nscs. |
2006-02-14 |
2023-08-12 |
rat |
| F Gottrup, C P Hovendal, D Anderse. Dopamine receptors do not influence beta2-sympathomimetic-mediated inhibition of gastric acid secretion in the dog. Scandinavian journal of gastroenterology. vol 16. issue 3. 2006-02-14. PMID:16435476. |
the effect of dopamine blockade by haloperidol and metoclopramide on beta2-adrenergic-induced changes of acid secretion and pulse rate was studied in conscious gastric fistula dogs. |
2006-02-14 |
2023-08-12 |
dog |
| E Obuchowicz, R Krysiak, J M Wieronska, M Smialowska, Z S Herma. Alterations in striatal neuropeptide Y system activity of rats with haloperidol-induced behavioral supersensitivity. Neuropeptides. vol 39. issue 5. 2006-02-03. PMID:16154634. |
the presented results suggest that the alterations in the activity of the striatal but not nucleus accumbens npy system contribute to adaptive changes induced by long-term haloperidol treatment and may be of significance to the motor hyperactivity induced by intermittent stimulation of postsynaptic dopamine d2 receptors. |
2006-02-03 |
2023-08-12 |
rat |
| Robert M Kessler, Mohammad Sib Ansari, Patrizia Riccardi, Rui Li, Karuna Jayathilake, Benoit Dawant, Herbert Y Meltze. Occupancy of striatal and extrastriatal dopamine D2/D3 receptors by olanzapine and haloperidol. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 12. 2006-01-24. PMID:16123775. |
occupancy of striatal and extrastriatal dopamine d2/d3 receptors by olanzapine and haloperidol. |
2006-01-24 |
2023-08-12 |
human |
| Robert M Kessler, Mohammad Sib Ansari, Patrizia Riccardi, Rui Li, Karuna Jayathilake, Benoit Dawant, Herbert Y Meltze. Occupancy of striatal and extrastriatal dopamine D2/D3 receptors by olanzapine and haloperidol. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 12. 2006-01-24. PMID:16123775. |
we performed [(18)f] fallypride pet studies in six schizophrenic subjects treated with olanzapine and six schizophrenic subjects treated with haloperidol to examine the occupancy of striatal and extrastriatal dopamine receptors by these antipsychotic drugs. |
2006-01-24 |
2023-08-12 |
human |
| Robert M Kessler, Mohammad Sib Ansari, Patrizia Riccardi, Rui Li, Karuna Jayathilake, Benoit Dawant, Herbert Y Meltze. Occupancy of striatal and extrastriatal dopamine D2/D3 receptors by olanzapine and haloperidol. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 12. 2006-01-24. PMID:16123775. |
occupancy of dopamine d(2)/d(3) receptors by olanzapine was not significantly different from that seen with haloperidol in the putamen, ventral striatum, medial thalamus, amygdala, or temporal cortex, that is, 67.5-78.2% occupancy; olanzapine produced no preferential occupancy of dopamine d(2)/d(3) receptors in the ventral striatum, medial thalamus, amygdala, or temporal cortex. |
2006-01-24 |
2023-08-12 |
human |
| S Roman, A Badia, P Camps, D Muñoz-Torrero, M V Clo. Nicotinic-receptor potentiator drugs, huprine X and galantamine, increase ACh release by blocking AChE activity but not acting on nicotinic receptors. Brain research. vol 1061. issue 2. 2006-01-17. PMID:16248990. |
after that, a wide range of concentrations of drugs, concomitantly with atr (0.1 microm), was studied in the presence of haloperidol (hal; 0.01 microm), a dopamine d2 antagonist. |
2006-01-17 |
2023-08-12 |
rat |
| Grzegorz Kuballa, Przemysław Nowak, Łukasz Labus, Aleksandra Bortel, Joanna Dabrowska, Marek Swoboda, Adam Kwieciński, Richard M Kostrzewa, Ryszard Bru. Central effects of nafadotride, a dopamine D3 receptor antagonist, in rats. Comparison with haloperidol and clozapine. Pharmacological reports : PR. vol 57. issue 2. 2006-01-12. PMID:15886414. |
the aim of this study was to examine behavioral and biochemical effects of nafadotride, the new dopamine d3 receptor antagonist, and to compare it with haloperidol (dopamine d2 receptor antagonist) and clozapine (predominate dopamine d4 receptor antagonist). |
2006-01-12 |
2023-08-12 |
rat |
| Grzegorz Kuballa, Przemysław Nowak, Łukasz Labus, Aleksandra Bortel, Joanna Dabrowska, Marek Swoboda, Adam Kwieciński, Richard M Kostrzewa, Ryszard Bru. Central effects of nafadotride, a dopamine D3 receptor antagonist, in rats. Comparison with haloperidol and clozapine. Pharmacological reports : PR. vol 57. issue 2. 2006-01-12. PMID:15886414. |
the results of the study indicate that nafadotride, the dopamine d3 receptor antagonist, has a behavioral and biochemical profile of action different from that of haloperidol but partially similar to that of clozapine. |
2006-01-12 |
2023-08-12 |
rat |
| Robert J Barrett, William F Caul, Randy Smit. Withdrawal, tolerance, and sensitization to dopamine mediated interoceptive cues in rats trained on a three-lever drug-discrimination task. Pharmacology, biochemistry, and behavior. vol 81. issue 1. 2005-12-30. PMID:15894057. |
in the present experiment rats were trained on a three-lever, drug-discrimination task to discriminate the cues associated with 0.30 mg/kg of the indirect dopamine (da) agonist, amphetamine (amph), saline (sal), and 0.03 mg/kg of the da, d2 receptor antagonist, haloperidol (hal). |
2005-12-30 |
2023-08-12 |
rat |
| Mark A Osinski, Marie E Uchic, Terese Seifert, Thomas K Shaughnessy, Loan N Miller, Masaki Nakane, Bryan F Cox, Jorge D Brioni, Robert B Morelan. Dopamine D2, but not D4, receptor agonists are emetogenic in ferrets. Pharmacology, biochemistry, and behavior. vol 81. issue 1. 2005-12-30. PMID:15894081. |
competitive antagonists of dopamine d2-like receptors (domperidone, haloperidol) dose-dependently blocked the emetic response to pnu95666e, a dopamine d2 receptor selective agonist. |
2005-12-30 |
2023-08-12 |
Not clear |
| Eyassu Chernet, Laura J Martin, Dominic Li, Anne B Need, Vanessa N Barth, Karen S Rash, Lee A Phebu. Use of LC/MS to assess brain tracer distribution in preclinical, in vivo receptor occupancy studies: dopamine D2, serotonin 2A and NK-1 receptors as examples. Life sciences. vol 78. issue 4. 2005-12-15. PMID:16139310. |
intravenous, subcutaneous and oral dose-occupancy curves were generated for haloperidol at the dopamine d2 receptor as were oral curves for the antipsychotic drugs olanzapine and clozapine. |
2005-12-15 |
2023-08-12 |
rat |