| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K K Anstrom, H C Cromwell, D J Woodwar. Effects of restraint and haloperidol on sensory gating in the midbrain of awake rats. Neuroscience. vol 146. issue 2. 2007-08-15. PMID:17360124. |
a further goal of this study was to determine if restraint, a classic model of stress known to increase extracellular dopamine levels, and systemic haloperidol injections affected inhibitory mechanisms involved in sensory gating. |
2007-08-15 |
2023-08-12 |
rat |
| Mahendra Bishnoi, Kanwaljit Chopra, Shrinivas K Kulkarn. Protective effect of adenosine reuptake inhibitors in haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes. Pharmacology. vol 79. issue 3. 2007-07-30. PMID:17377417. |
chronic administration of haloperidol also resulted in the development of dopamine sensitivity as suggested by increased locomotor activity and stereotypy and decreased % retention time on elevated plus maze paradigm. |
2007-07-30 |
2023-08-12 |
rat |
| Mahendra Bishnoi, Kanwaljit Chopra, Shrinivas K Kulkarn. Protective effect of adenosine reuptake inhibitors in haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes. Pharmacology. vol 79. issue 3. 2007-07-30. PMID:17377417. |
chronic administration of haloperidol resulted in decreased turnover of dopamine and norepinephrine in both cortex and subcortical regions which was dose-dependently prevented by adenosine reuptake/transport inhibitors. |
2007-07-30 |
2023-08-12 |
rat |
| Marko Schirmer, Alina Lessenich, Sven Lindemann, Wolfgang Lösche. Marked differences in response to dopamine receptor antagonism in two rat mutants, ci2 and ci3, with lateralized rotational behavior. Behavioural brain research. vol 180. issue 2. 2007-07-24. PMID:17442411. |
when animals were observed during the light phase, the abnormal rotational behavior of the mutants was not significantly affected by haloperidol, whereas the dopamine d2 receptor-preferring antagonist raclopride significantly reduced rotations in ci2 rats. |
2007-07-24 |
2023-08-12 |
rat |
| Carlos F Aparici. Haloperidol, dynamics of choice, and the parameters of the matching law. Behavioural processes. vol 75. issue 2. 2007-07-06. PMID:17398038. |
the present study shows that haloperidol, a dopamine antagonist, does not eliminate the reinforcing value of food reinforcers. |
2007-07-06 |
2023-08-12 |
rat |
| Theo Hatzipetros, Jamie G Raudensky, Jean-Jacques Soghomonian, Bryan K Yamamot. Haloperidol treatment after high-dose methamphetamine administration is excitotoxic to GABA cells in the substantia nigra pars reticulata. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 22. 2007-06-13. PMID:17537960. |
the therapeutic management of methamphetamine (meth)-induced psychoses often involves treatment with the typical antipsychotic drug and dopamine d2 receptor antagonist haloperidol. |
2007-06-13 |
2023-08-12 |
rat |
| Alberto Ambesi-Impiombato, Fabio Panariello, Carmela Dell'aversano, Carmine Tomasetti, Giovanni Muscettola, Andrea de Bartolomei. Differential expression of Homer 1 gene by acute and chronic administration of antipsychotics and dopamine transporter inhibitors in the rat forebrain. Synapse (New York, N.Y.). vol 61. issue 6. 2007-06-01. PMID:17372981. |
rats were treated with the "typical" antipsychotic haloperidol, the "atypical" quetiapine, or the selective dopamine transporter (dat) inhibitor gbr 12909 in acute and chronic paradigms. |
2007-06-01 |
2023-08-12 |
rat |
| Alberto Ambesi-Impiombato, Fabio Panariello, Carmela Dell'aversano, Carmine Tomasetti, Giovanni Muscettola, Andrea de Bartolomei. Differential expression of Homer 1 gene by acute and chronic administration of antipsychotics and dopamine transporter inhibitors in the rat forebrain. Synapse (New York, N.Y.). vol 61. issue 6. 2007-06-01. PMID:17372981. |
our results show that the high affinity dopamine d(2) receptor antagonist haloperidol strongly induces homer 1 gene expression in the caudate-putamen, whereas quetiapine, a fast d2r dissociating antagonist, does not. |
2007-06-01 |
2023-08-12 |
rat |
| Xueliang Fan, Ellen J Hes. D2-like dopamine receptors mediate the response to amphetamine in a mouse model of ADHD. Neurobiology of disease. vol 26. issue 1. 2007-05-08. PMID:17291774. |
however, the d2-like dopamine receptor antagonists haloperidol and raclopride, but not the d1-like dopamine receptor antagonist sch23390, blocked the amphetamine-induced reduction in locomotor activity in coloboma mice, providing direct evidence that d2-like dopamine receptors mediate the effect of amphetamine in these mice. |
2007-05-08 |
2023-08-12 |
mouse |
| N V Zvezdochkina, L N Muranova, V V Andrianov, S S Arkhipova, Kh L Gainutdinov, A I Golubev, I N Pleshchinski. Locomotor responses and neuron excitability in conditions of haloperidol blockade of dopamine in invertebrates and vertebrates. Neuroscience and behavioral physiology. vol 36. issue 1. 2007-05-01. PMID:16328166. |
locomotor responses and neuron excitability in conditions of haloperidol blockade of dopamine in invertebrates and vertebrates. |
2007-05-01 |
2023-08-12 |
rat |
| N V Zvezdochkina, L N Muranova, V V Andrianov, S S Arkhipova, Kh L Gainutdinov, A I Golubev, I N Pleshchinski. Locomotor responses and neuron excitability in conditions of haloperidol blockade of dopamine in invertebrates and vertebrates. Neuroscience and behavioral physiology. vol 36. issue 1. 2007-05-01. PMID:16328166. |
blockade of dopamine receptors with haloperidol led to suppression of locomotor activity in both groups of rats; in common snails, haloperidol decreased the rate of locomotion. |
2007-05-01 |
2023-08-12 |
rat |
| Kurt Rasmussen, Mei-Ann Hsu, Yili Yan. The orexin-1 receptor antagonist SB-334867 blocks the effects of antipsychotics on the activity of A9 and A10 dopamine neurons: implications for antipsychotic therapy. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 4. 2007-05-01. PMID:17063151. |
recordings from midbrain dopamine neurons showed that acute administration of sb-334867 alone did not alter the number of spontaneously active a9 or a10 cells, but did reverse: (1) the increase in the number of spontaneously active a9 and/or a10 dopamine cells caused by the acute administration of haloperidol (1 mg/kg, subcutaneous) or olanzapine (10 mg/kg, s.c.) and (2) the decrease in the number of spontaneously active a9 and/or a10 dopamine cells caused by the chronic administration of haloperidol (1 mg/kg/day x 21 days, s.c.) or olanzapine (10 mg/kg/day x 21 days, s.c.). |
2007-05-01 |
2023-08-12 |
rat |
| Catalin V Buhusi, Warren H Mec. Effect of clozapine on interval timing and working memory for time in the peak-interval procedure with gaps. Behavioural processes. vol 74. issue 2. 2007-05-01. PMID:17141425. |
for example, dopamine agonist methamphetamine increases the speed of an internal clock and resets timing after a gap, while dopamine antagonist haloperidol decreases the speed of an internal clock and stops timing during a gap [buhusi, c.v., meck, w.h., 2002. |
2007-05-01 |
2023-08-12 |
rat |
| Shinya Uchida, Yasuhiro Kato, Kazufumi Hirano, Yoshiyuki Kagawa, Shizuo Yamad. Brain neurotransmitter receptor-binding characteristics in rats after oral administration of haloperidol, risperidone and olanzapine. Life sciences. vol 80. issue 17. 2007-05-01. PMID:17316700. |
the present study was conducted to characterize the binding of neurotransmitter receptors (dopamine d(2), serotonin 5-ht(2), histamine h(1), adrenaline alpha(1) and muscarine m(l) receptors) in the rat's brain after the oral administration of haloperidol, risperidone, and olanzapine. |
2007-05-01 |
2023-08-12 |
rat |
| Shaun Jordan, Janelle L Johnson, Karen Regardie, Ruoyan Chen, Vuk Koprivica, Yoshihiro Tadori, Junichi Kambayashi, Hisashi Kitagawa, Tetsuro Kikuch. Dopamine D2 receptor partial agonists display differential or contrasting characteristics in membrane and cell-based assays of dopamine D2 receptor signaling. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 2. 2007-04-24. PMID:17070976. |
dopamine activity was blocked in each case by (-)raclopride, which was inactive on its own in every assay, as were the antipsychotics haloperidol, olanzapine, ziprasidone and clozapine. |
2007-04-24 |
2023-08-12 |
human |
| Mahendra Bishnoi, Anil Kumar, Kanwaljit Chopra, Shrinivas K Kulkarn. Comparative neurochemical changes associated with chronic administration of typical and atypical neuroleptics: implications in tardive dyskinesia. Indian journal of experimental biology. vol 45. issue 2. 2007-04-10. PMID:17375557. |
there were also significant decrease in the extracellular levels of neurotransmitters dopamine, norepinephrine and serotonin in fore-brain as measured by hplc/ed after chronic administration of haloperidol and chlorpromazine. |
2007-04-10 |
2023-08-12 |
rat |
| Maarten van den Buuse, Andrea Gogo. Differential effects of antipsychotic drugs on serotonin-1A receptor-mediated disruption of prepulse inhibition. The Journal of pharmacology and experimental therapeutics. vol 320. issue 3. 2007-04-09. PMID:17194799. |
the action of haloperidol and raclopride suggests a major involvement of dopamine d(2) receptors in this effect, possibly downstream from the initial serotonergic stimulation. |
2007-04-09 |
2023-08-12 |
rat |
| Martin Hadamitzky, Silke Harich, Michael Koch, Kerstin Schwab. Deficient prepulse inhibition induced by selective breeding of rats can be restored by the dopamine D2 antagonist haloperidol. Behavioural brain research. vol 177. issue 2. 2007-04-05. PMID:17182114. |
deficient prepulse inhibition induced by selective breeding of rats can be restored by the dopamine d2 antagonist haloperidol. |
2007-04-05 |
2023-08-12 |
rat |
| Zhu Li, Mei Huang, Adam J Prus, Jin Dai, Herbert Y Meltze. 5-HT6 receptor antagonist SB-399885 potentiates haloperidol and risperidone-induced dopamine efflux in the medial prefrontal cortex or hippocampus. Brain research. vol 1134. issue 1. 2007-04-05. PMID:17207474. |
5-ht6 receptor antagonist sb-399885 potentiates haloperidol and risperidone-induced dopamine efflux in the medial prefrontal cortex or hippocampus. |
2007-04-05 |
2023-08-12 |
rat |
| Anne-Noël Samaha, Philip Seeman, Jane Stewart, Heshmat Rajabi, Shitij Kapu. "Breakthrough" dopamine supersensitivity during ongoing antipsychotic treatment leads to treatment failure over time. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 11. 2007-04-05. PMID:17360921. |
to explore potential mechanisms, we studied presynaptic and postsynaptic elements of the dopamine system and observed that antipsychotic failure was accompanied by opposing changes across the synapse: tolerance to the ability of haloperidol to increase basal dopamine and dopamine turnover on one side, and 20-40% increases in d2 receptor number and 100-160% increases in the proportion of d2 receptors in the high-affinity state for dopamine (d2(high)) on the other. |
2007-04-05 |
2023-08-12 |
rat |