| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mahadevan Gajendira. Differential effects of spinal 5-HT1A receptor activation and 5-HT2A/2C receptor desensitization by chronic haloperidol. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 7. 2007-12-06. PMID:17688988. |
these results demonstrate that the effects of haloperidol on the activation and desensitization of 5-ht(1a) and 5-ht(2a/2c) receptors respectively, may be mediated via intracellular mechanisms shared by these receptors with dopamine d(2) receptors in the mammalian spinal cord. |
2007-12-06 |
2023-08-12 |
rat |
| M A Cheido, G V Idov. The differential contribution of dopamine D(1) and D (2) receptors to mu-opioidergic immunomodulation. Neuroscience and behavioral physiology. vol 37. issue 7. 2007-12-06. PMID:17763992. |
this effect of the mu agonist was prevented by prior blockade of dopamine d(2) receptors with haloperidol (2 mg/kg). |
2007-12-06 |
2023-08-12 |
mouse |
| Elise Morice, Jean-Marie Billard, Cécile Denis, Flavie Mathieu, Catalina Betancur, Jacques Epelbaum, Bruno Giros, Marika Nosten-Bertran. Parallel loss of hippocampal LTD and cognitive flexibility in a genetic model of hyperdopaminergia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 10. 2007-11-20. PMID:17342172. |
both the electrophysiological and behavioral phenotypes are reversed by the dopamine antagonist haloperidol, suggesting that hyperdopaminergia is involved in these deficits. |
2007-11-20 |
2023-08-12 |
mouse |
| Hsien-Sung Huang, Anouch Matevossian, Catheryne Whittle, Se Young Kim, Armin Schumacher, Stephen P Baker, Schahram Akbaria. Prefrontal dysfunction in schizophrenia involves mixed-lineage leukemia 1-regulated histone methylation at GABAergic gene promoters. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 42. 2007-11-08. PMID:17942719. |
these effects were not mimicked by haloperidol or genetic ablation of dopamine d2 and d3 receptors, suggesting that blockade of d2-like signaling is not sufficient for clozapine-induced histone methylation. |
2007-11-08 |
2023-08-12 |
mouse |
| Joseph Gabriele, Nancy Thomas, Sevil N-Marandi, Ram Mishr. Differential modulation of a 40 kDa catecholamine regulated protein in the core and shell subcompartments of the nucleus accumbens following chronic quinpirole and haloperidol administration in the rat. Synapse (New York, N.Y.). vol 61. issue 10. 2007-10-31. PMID:17603808. |
past reports have shown dopamine (da) d2/d3 receptor agonist quinpirole (qnp) and the da d2 receptor antagonist, haloperidol (hal) display a significant increase in expression of catecholamine regulated protein (crp40) in the nucleus accumbens (nacc) and the striatum, respectively. |
2007-10-31 |
2023-08-12 |
rat |
| Mahesh Menon, Jimmy Jensen, Irina Vitcu, Ariel Graff-Guerrero, Adrian Crawley, Mark A Smith, Shitij Kapu. Temporal difference modeling of the blood-oxygen level dependent response during aversive conditioning in humans: effects of dopaminergic modulation. Biological psychiatry. vol 62. issue 7. 2007-10-29. PMID:17224134. |
we hypothesized that dopamine would modulate the pe related signal in aversive conditioning and that haloperidol would reduce pe related activity, while an acute dose of amphetamine would increase pe related activity in the ventral striatum. |
2007-10-29 |
2023-08-12 |
Not clear |
| Michelle R Ciucci, Sean T Ma, Cynthia Fox, Jacqueline R Kane, Lorraine O Ramig, Timothy Schaller. Qualitative changes in ultrasonic vocalization in rats after unilateral dopamine depletion or haloperidol: a preliminary study. Behavioural brain research. vol 182. issue 2. 2007-10-26. PMID:17397940. |
qualitative changes in ultrasonic vocalization in rats after unilateral dopamine depletion or haloperidol: a preliminary study. |
2007-10-26 |
2023-08-12 |
rat |
| Michelle R Ciucci, Sean T Ma, Cynthia Fox, Jacqueline R Kane, Lorraine O Ramig, Timothy Schaller. Qualitative changes in ultrasonic vocalization in rats after unilateral dopamine depletion or haloperidol: a preliminary study. Behavioural brain research. vol 182. issue 2. 2007-10-26. PMID:17397940. |
the data suggest that mild transient dopamine depletion with haloperidol or even unilateral degeneration of dopamine neurons is associated with changes in the usv acoustic signal. |
2007-10-26 |
2023-08-12 |
rat |
| Shaun Jordan, Karen Regardie, Janelle L Johnson, Ruoyan Chen, Junichi Kambayashi, Robert McQuade, Hisashi Kitagawa, Yoshihiro Tadori, Tetsuro Kikuch. In vitro functional characteristics of dopamine D2 receptor partial agonists in second and third messenger-based assays of cloned human dopamine D2Long receptor signalling. Journal of psychopharmacology (Oxford, England). vol 21. issue 6. 2007-10-18. PMID:17092971. |
these drug effects on ca(2+) mobilization and erk2 phosphoprotein expression were mediated through dopamine hd(2l) receptors, as they all were blocked by (-)raclopride, whereas (-)raclopride and other dopamine d(2) receptor antagonists (haloperidol, risperidone, ziprasidone, olanzapine, clozapine and quetiapine) were inactive on their own in both assays. |
2007-10-18 |
2023-08-12 |
human |
| Yechiel Levkovitz, Uri Levi, Yoram Braw, Hagit Cohe. Minocycline, a second-generation tetracycline, as a neuroprotective agent in an animal model of schizophrenia. Brain research. vol 1154. 2007-10-12. PMID:17488642. |
the effects of minocycline were compared to those of haloperidol, a dopamine antagonist used for the treatment of schizophrenia. |
2007-10-12 |
2023-08-12 |
rat |
| F M Theisen, M Haberhausen, M A Firnges, P Gregory, J H Reinders, H Remschmidt, J Hebebrand, J Ante. No evidence for binding of clozapine, olanzapine and/or haloperidol to selected receptors involved in body weight regulation. The pharmacogenomics journal. vol 7. issue 4. 2007-09-27. PMID:16983399. |
in contrast, the binding profile of haloperidol was substantially different (high affinity only for the dopamine d1 receptor). |
2007-09-27 |
2023-08-12 |
Not clear |
| Martin Zack, Constantine X Poulo. A D2 antagonist enhances the rewarding and priming effects of a gambling episode in pathological gamblers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 8. 2007-09-26. PMID:17203013. |
to investigate this issue, the present study assessed the effects of the relatively selective dopamine d2 antagonist, haloperidol (3 mg, oral) on responses to actual gambling (15 min on a slot machine) in 20 non-comorbid pathological gamblers and 18 non-gambler controls in a placebo-controlled, double-blind, counterbalanced design. |
2007-09-26 |
2023-08-12 |
Not clear |
| Myoung-Sun Roh, Myoung Suk Seo, Yeni Kim, Se Hyun Kim, Won Je Jeon, Yong Min Ahn, Ung Gu Kang, Yong Sung Juhnn, Yong Sik Ki. Haloperidol and clozapine differentially regulate signals upstream of glycogen synthase kinase 3 in the rat frontal cortex. Experimental & molecular medicine. vol 39. issue 3. 2007-09-24. PMID:17603289. |
haloperidol is a typical antipsychotic with potent dopamine d(2) receptor antagonism. |
2007-09-24 |
2023-08-12 |
rat |
| M Bishnoi, K Chopra, S K Kulkarn. Neurochemical changes associated with chronic administration of typical antipsychotics and its relationship with tardive dyskinesia. Methods and findings in experimental and clinical pharmacology. vol 29. issue 3. 2007-08-30. PMID:17520104. |
in the present study we planned to study time-dependent changes in extracellular levels of norepinephrine, dopamine and serotonin in cortical and subcortical (including striatum) regions of brain and tried to correlate them with hyperkinetic motor activities (vacuous chewing movements [vcms], tongue protrusions and facial jerking) in rats treated chronically with typical neuroleptics (haloperidol and chlorpromazine). |
2007-08-30 |
2023-08-12 |
rat |
| Mahendra Bishnoi, Kanwaljit Chopra, Shrinivas K Kulkarn. Possible anti-oxidant and neuroprotective mechanisms of zolpidem in attenuating typical anti-psychotic-induced orofacial dyskinesia: a biochemical and neurochemical study. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 5. 2007-08-28. PMID:17513028. |
neurochemical analysis (neurotransmitter and their metabolite level estimation) revealed that haloperidol and chlorpromazine significantly decreased the dopamine, norepinephrine and serotonin levels in brain homogenates where as it caused a significant increase in the metabolite (vma and hva) levels in urine, which were significantly reversed by zolpidem at higher doses. |
2007-08-28 |
2023-08-12 |
rat |
| K K Anstrom, H C Cromwell, D J Woodwar. Effects of restraint and haloperidol on sensory gating in the midbrain of awake rats. Neuroscience. vol 146. issue 2. 2007-08-15. PMID:17360124. |
a further goal of this study was to determine if restraint, a classic model of stress known to increase extracellular dopamine levels, and systemic haloperidol injections affected inhibitory mechanisms involved in sensory gating. |
2007-08-15 |
2023-08-12 |
rat |
| Mahendra Bishnoi, Kanwaljit Chopra, Shrinivas K Kulkarn. Protective effect of adenosine reuptake inhibitors in haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes. Pharmacology. vol 79. issue 3. 2007-07-30. PMID:17377417. |
chronic administration of haloperidol also resulted in the development of dopamine sensitivity as suggested by increased locomotor activity and stereotypy and decreased % retention time on elevated plus maze paradigm. |
2007-07-30 |
2023-08-12 |
rat |
| Mahendra Bishnoi, Kanwaljit Chopra, Shrinivas K Kulkarn. Protective effect of adenosine reuptake inhibitors in haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes. Pharmacology. vol 79. issue 3. 2007-07-30. PMID:17377417. |
chronic administration of haloperidol resulted in decreased turnover of dopamine and norepinephrine in both cortex and subcortical regions which was dose-dependently prevented by adenosine reuptake/transport inhibitors. |
2007-07-30 |
2023-08-12 |
rat |
| Marko Schirmer, Alina Lessenich, Sven Lindemann, Wolfgang Lösche. Marked differences in response to dopamine receptor antagonism in two rat mutants, ci2 and ci3, with lateralized rotational behavior. Behavioural brain research. vol 180. issue 2. 2007-07-24. PMID:17442411. |
when animals were observed during the light phase, the abnormal rotational behavior of the mutants was not significantly affected by haloperidol, whereas the dopamine d2 receptor-preferring antagonist raclopride significantly reduced rotations in ci2 rats. |
2007-07-24 |
2023-08-12 |
rat |
| Carlos F Aparici. Haloperidol, dynamics of choice, and the parameters of the matching law. Behavioural processes. vol 75. issue 2. 2007-07-06. PMID:17398038. |
the present study shows that haloperidol, a dopamine antagonist, does not eliminate the reinforcing value of food reinforcers. |
2007-07-06 |
2023-08-12 |
rat |