| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ingo Vernaleken, Yoshitaka Kumakura, Hans-Georg Buchholz, Thomas Siessmeier, Ralf-Dieter Hilgers, Peter Bartenstein, Paul Cumming, Gerhard Gründe. Baseline [18F]-FDOPA kinetics are predictive of haloperidol-induced changes in dopamine turnover and cognitive performance: A positron emission tomography study in healthy subjects. NeuroImage. vol 40. issue 3. 2008-06-17. PMID:18262797. |
we conclude that the initial increase of [(18)f]fluorodopamine turnover after acute haloperidol challenge is associated with an over-stimulation in individuals with initially more pharmacologically responsive dopamine systems, but optimizes cognitive performance in those with lower normal fdopa utilization at baseline. |
2008-06-17 |
2023-08-12 |
human |
| Shinobu Ito, Tomohisa Mori, Toshiko Sawaguch. Dopamine-independent psychostimulant activity of a delta-agonist. Behavioural pharmacology. vol 19. issue 2. 2008-06-17. PMID:18332675. |
although haloperidol (dopamine d2-receptor antagonist) did not affect snc80-induced hyperactivity, it inhibited morphine-induced hyperlocomotion. |
2008-06-17 |
2023-08-12 |
mouse |
| Philip Seema. Dopamine D2(High) receptors moderately elevated by sertindole. Synapse (New York, N.Y.). vol 62. issue 5. 2008-06-03. PMID:18293356. |
although the findings suggest that rats or patients treated with sertindole might exhibit behavioral dopamine supersensitivity, the drug-induced increase in d2(high) receptors was less than that previously found with haloperidol. |
2008-06-03 |
2023-08-12 |
rat |
| L N Markova, T V Ostroumova, M G Akimov, V V Bezuglo. [N-arachidonoyl dopamine is a possible factor of the rate of tentacle formation in freshwater hydra]. Ontogenez. vol 39. issue 1. 2008-06-03. PMID:18409382. |
the effect of n-arachidonoyl dopamine, haloperidol, and their mixture on the rate of tentacle formation was studied during regeneration of the gastral and basal fragments of freshwater hydra. |
2008-06-03 |
2023-08-12 |
Not clear |
| Mahendra Bishnoi, Kanwaljit Chopra, Shrinivas K Kulkarn. Progesterone attenuates neuroleptic-induced orofacial dyskinesia via the activity of its metabolite, allopregnanolone, a positive GABA(A) modulating neurosteroid. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 2. 2008-05-30. PMID:17988775. |
further, chronic administration of haloperidol resulted in significant decrease in dopamine levels in rat striatum homogenates and increase in catecholamine metabolite levels. |
2008-05-30 |
2023-08-12 |
rat |
| Mahendra Bishnoi, Kanwaljit Chopra, Shrinivas K Kulkarn. Progesterone attenuates neuroleptic-induced orofacial dyskinesia via the activity of its metabolite, allopregnanolone, a positive GABA(A) modulating neurosteroid. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 2. 2008-05-30. PMID:17988775. |
coadministration of progesterone also reversed the decrease in dopamine levels induced by chronic haloperidol treatment, an effect which was again reversed by pre treatment with finasteride. |
2008-05-30 |
2023-08-12 |
rat |
| Mahendra Bishnoi, Kanwaljit Chopra, Shrinivas K Kulkarn. Protective effect of Curcumin, the active principle of turmeric (Curcuma longa) in haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes in rat brain. Pharmacology, biochemistry, and behavior. vol 88. issue 4. 2008-05-08. PMID:18022680. |
on chronic administration of haloperidol, there was a decrease in turnover of dopamine, serotonin and norepinephrine in both cortical and subcortical regions which was again dose-dependently reversed by treatment with curcumin. |
2008-05-08 |
2023-08-12 |
rat |
| Susanne Nikolaus, Rolf Larisch, Markus Beu, Christina Antke, Konstantin Kley, Farhad Forutan, Andreas Wirrwar, Hans-Wilhelm Mülle. Investigating the dopaminergic synapse in vivo. II. Molecular imaging studies in small laboratory animals. Reviews in the neurosciences. vol 18. issue 6. 2008-05-02. PMID:18330213. |
finally, preliminary results yielded the first evidence that acute pplication of haloperidol might induce a reduction of dopamine transporter binding, indicating an enhancement of dopamine release into the synaptic cleft. |
2008-05-02 |
2023-08-12 |
mouse |
| C Tomasetti, C Dell'Aversano, F Iasevoli, A de Bartolomei. Homer splice variants modulation within cortico-subcortical regions by dopamine D2 antagonists, a partial agonist, and an indirect agonist: implication for glutamatergic postsynaptic density in antipsychotics action. Neuroscience. vol 150. issue 1. 2008-03-28. PMID:17916411. |
animals were treated with the typical antipsychotic haloperidol 0.8 mg/kg, the atypical antipsychotic clozapine 15 mg/kg, the dopamine partial agonist aripiprazole 12 mg/kg and 30 mg/kg and the dopamine transporter inhibitor gbr12909 30 mg/kg in acute and chronic paradigms. |
2008-03-28 |
2023-08-12 |
rat |
| Y Chertkow, O Weinreb, M B H Youdim, H Silve. Dopamine and serotonin metabolism in response to chronic administration of fluvoxamine and haloperidol combined treatment. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 11. 2008-03-11. PMID:17576515. |
dopamine and serotonin metabolism in response to chronic administration of fluvoxamine and haloperidol combined treatment. |
2008-03-11 |
2023-08-12 |
rat |
| Y Chertkow, O Weinreb, M B H Youdim, H Silve. Dopamine and serotonin metabolism in response to chronic administration of fluvoxamine and haloperidol combined treatment. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 11. 2008-03-11. PMID:17576515. |
we studied dopamine and serotonin metabolism in different rat brain areas at 1.5 and 24 h after the last dosage of chronic treatment (30 days), with haloperidol plus fluvoxamine, each drug alone, and clozapine. |
2008-03-11 |
2023-08-12 |
rat |
| Y Chertkow, O Weinreb, M B H Youdim, H Silve. Dopamine and serotonin metabolism in response to chronic administration of fluvoxamine and haloperidol combined treatment. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 11. 2008-03-11. PMID:17576515. |
haloperidol-fluvoxamine combination, haloperidol, and clozapine treatments increased striatal and frontal cortex dopamine turnover and reduced striatal tyrosine hydroxylase activity at 1.5 h. at 24 h both dopamine turnover and tyrosine hydroxylase activity were reduced. |
2008-03-11 |
2023-08-12 |
rat |
| Y Chertkow, O Weinreb, M B H Youdim, H Silve. Dopamine and serotonin metabolism in response to chronic administration of fluvoxamine and haloperidol combined treatment. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 11. 2008-03-11. PMID:17576515. |
thus, in chronically treated animals, release of striatal dopamine increases following a drug pulse and returns to baseline by 24 h. serotonin and 5-hydroxyindoleacetic acid concentrations were decreased at 1.5 h in haloperidol-fluvoxamine and clozapine groups and returned to normal levels by 24 h. a limited behavioral assessment showed that treatment with haloperidol plus fluvoxamine reduced motor activity compared to haloperidol, and increased sniffing compared to haloperidol, fluvoxamine and clozapine. |
2008-03-11 |
2023-08-12 |
rat |
| Kurt Rasmussen, Mei-Ann Hsu, Stephen Noone, Bryan G Johnson, Linda K Thompson, Susan K Hemrick-Lueck. The orexin-1 antagonist SB-334867 blocks antipsychotic treatment emergent catalepsy: implications for the treatment of extrapyramidal symptoms. Schizophrenia bulletin. vol 33. issue 6. 2008-02-27. PMID:17660489. |
we have previously shown that the orexin-1 antagonist sb-334867 blocks the electrophysiological effects of haloperidol and olanzapine on the activity of a9 and a10 dopamine neurons. |
2008-02-27 |
2023-08-12 |
Not clear |
| Vera Bubenikova-Valesova, Ales Stuchlik, Jan Svoboda, Jan Bures, Karel Vale. Risperidone and ritanserin but not haloperidol block effect of dizocilpine on the active allothetic place avoidance task. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 3. 2008-02-12. PMID:18195350. |
the aim of the present work was to establish the effect of the 5-ht2a/2c receptor antagonist ritanserin (2.5 or 5 mg/kg), the dopamine d2 antagonist haloperidol (0.1 or 1 mg/kg), and the atypical antipsychotic risperidone (0.1 mg/kg or 1 mg/kg), which is an antagonist of both 5-ht2a/2c and d2 receptors, on cognitive deficit induced by subchronic administration of dizocilpine (mk-801, 0.1 mg/kg). |
2008-02-12 |
2023-08-12 |
rat |
| Julia Flores-Tochihuitl, Guillermo Vargas, Julio Cesar Morales-Medina, Gustavo Rivera, Fidel De La Cruz, Sergio Zamudio, Gonzalo Flore. Enhanced apomorphine sensitivity and increased binding of dopamine D2 receptors in nucleus accumbens in prepubertal rats after neonatal blockade of the dopamine D3 receptors by (+)-S14297. Synapse (New York, N.Y.). vol 62. issue 1. 2008-01-22. PMID:17957737. |
past studies have only tested behavioral changes induced by neonatal administration of nonselective dopamine antagonist such as haloperidol or sulpiride in adult rats. |
2008-01-22 |
2023-08-12 |
rat |
| Mahendra Bishnoi, Kanwaljit Chopra, Shrinivas K Kulkarn. Theophylline, adenosine receptor antagonist prevents behavioral, biochemical and neurochemical changes associated with an animal model of tardive dyskinesia. Pharmacological reports : PR. vol 59. issue 2. 2008-01-17. PMID:17556796. |
chronic administration of haloperidol resulted in a decrease in dopamine levels which was reversed by treatment with theophylline (at higher doses). |
2008-01-17 |
2023-08-12 |
rat |
| J Lee, W J Rushlow, N Rajakuma. L-type calcium channel blockade on haloperidol-induced c-Fos expression in the striatum. Neuroscience. vol 149. issue 3. 2008-01-16. PMID:17913375. |
induction of c-fos in the striatum by haloperidol involves dopamine d(2) (da d(2)) receptor antagonism and is dependent on activation of n-methyl-d-aspartate (nmda) receptors and l-type ca(2+) channels. |
2008-01-16 |
2023-08-12 |
rat |
| Mahendra Bishnoi, Kanwaljit Chopra, Shrinivas K Kulkarn. Protective effect of rutin, a polyphenolic flavonoid against haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes. Fundamental & clinical pharmacology. vol 21. issue 5. 2008-01-03. PMID:17868205. |
although turnover of dopamine and noradrenaline decreased in both cortical and subcortical regions after chronic administration of haloperidol, it was significantly reversed by high-dose rutin treatment. |
2008-01-03 |
2023-08-12 |
rat |
| Roselei Fachinetto, Jardel G Villarinho, Caroline Wagner, Romaiana P Pereira, Daiana Silva Avila, Marilise E Burger, João Batista Calixto, João B T Rocha, Juliano Ferreir. Valeriana officinalis does not alter the orofacial dyskinesia induced by haloperidol in rats: role of dopamine transporter. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 7. 2007-12-06. PMID:17669571. |
valeriana officinalis does not alter the orofacial dyskinesia induced by haloperidol in rats: role of dopamine transporter. |
2007-12-06 |
2023-08-12 |
rat |