| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Liesbeth A Bruins Slot, Fabrice Lestienne, Catherine Grevoz-Barret, Adrian Newman-Tancredi, Didier Cussa. F15063, a potential antipsychotic with dopamine D(2)/D(3) receptor antagonist and 5-HT(1A) receptor agonist properties: influence on immediate-early gene expression in rat prefrontal cortex and striatum. European journal of pharmacology. vol 620. issue 1-3. 2009-12-31. PMID:19695244. |
we investigated the effects of the putative antipsychotic drug n-[(2,2-dimethyl-2,3-dihydro-benzofuran-7-yloxy)ethyl]-3-(cyclopent-1-enyl)-benzylamine (f15063), a compound that targets both dopamine d(2) and serotonin 5-ht(1a) receptors, in comparison with haloperidol and clozapine on rat mrna expression of ieg i.e. |
2009-12-31 |
2023-08-12 |
rat |
| Changjiu Zhao, Ming L. The receptor mechanisms underlying the disruptive effects of haloperidol and clozapine on rat maternal behavior: a double dissociation between dopamine D(2) and 5-HT(2A/2C) receptors. Pharmacology, biochemistry, and behavior. vol 93. issue 4. 2009-11-27. PMID:19539643. |
the receptor mechanisms underlying the disruptive effects of haloperidol and clozapine on rat maternal behavior: a double dissociation between dopamine d(2) and 5-ht(2a/2c) receptors. |
2009-11-27 |
2023-08-12 |
rat |
| Changjiu Zhao, Ming L. The receptor mechanisms underlying the disruptive effects of haloperidol and clozapine on rat maternal behavior: a double dissociation between dopamine D(2) and 5-HT(2A/2C) receptors. Pharmacology, biochemistry, and behavior. vol 93. issue 4. 2009-11-27. PMID:19539643. |
postpartum rats were administered with haloperidol (0.2 mg/kg, sc) or clozapine (10.0 mg/kg, sc) together with either vehicle (saline or water), quinpirole (a selective dopamine d(2)/d(3) agonist, 0.5 or 1.0 mg/kg, sc), or 2,5-dimethoxy-4-iodo-amphetamine (doi, a selective 5-ht(2a/2c) agonist, 1.0 or 2.5 mg/kg, sc), and their maternal behaviors were tested at different time points before and after drug administration. |
2009-11-27 |
2023-08-12 |
rat |
| Changjiu Zhao, Ming L. The receptor mechanisms underlying the disruptive effects of haloperidol and clozapine on rat maternal behavior: a double dissociation between dopamine D(2) and 5-HT(2A/2C) receptors. Pharmacology, biochemistry, and behavior. vol 93. issue 4. 2009-11-27. PMID:19539643. |
specifically, haloperidol disrupts maternal behavior primarily by blocking dopamine d(2) receptors, whereas clozapine exerts its disruptive effect primarily by blocking the 5-ht(2a/2c) receptors. |
2009-11-27 |
2023-08-12 |
rat |
| K Inada, J S Farrington, S S Moy, B H Koller, G E Dunca. Assessment of NMDA receptor activation in vivo by Fos induction after challenge with the direct NMDA agonist (tetrazol-5-yl)glycine: effects of clozapine and haloperidol. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 7. 2009-11-23. PMID:17318306. |
the relatively high dose (1 mg/kg) of haloperidol required to block effects of tzg suggests that this action may not be related to the d(2) dopamine receptor-blocking properties, since maximal d(2) receptor blockade was probably achieved by the 0.5 mg/kg dose of haloperidol. |
2009-11-23 |
2023-08-12 |
mouse |
| Burkhard Pleger, Christian C Ruff, Felix Blankenburg, Stefan Klöppel, Jon Driver, Raymond J Dola. Influence of dopaminergically mediated reward on somatosensory decision-making. PLoS biology. vol 7. issue 7. 2009-11-17. PMID:19636360. |
prior to the procedure, participants received either placebo (saline), a dopamine agonist (levodopa), or an antagonist (haloperidol). |
2009-11-17 |
2023-08-12 |
human |
| Hidehiro Oshibuchi, Ken Inada, Hiroko Sugawara, Jun Ishigook. Aripiprazole and haloperidol suppress excessive dopamine release in the amygdala in response to conditioned fear stress, but show contrasting effects on basal dopamine release in methamphetamine-sensitized rats. European journal of pharmacology. vol 615. issue 1-3. 2009-11-10. PMID:19477171. |
aripiprazole and haloperidol suppress excessive dopamine release in the amygdala in response to conditioned fear stress, but show contrasting effects on basal dopamine release in methamphetamine-sensitized rats. |
2009-11-10 |
2023-08-12 |
rat |
| Hidehiro Oshibuchi, Ken Inada, Hiroko Sugawara, Jun Ishigook. Aripiprazole and haloperidol suppress excessive dopamine release in the amygdala in response to conditioned fear stress, but show contrasting effects on basal dopamine release in methamphetamine-sensitized rats. European journal of pharmacology. vol 615. issue 1-3. 2009-11-10. PMID:19477171. |
aripiprazole is the first antipsychotic drug with an action involving partial dopamine d(2) receptor agonism, thus differing from haloperidol, a typical antipsychotic that shows selective dopamine d(2) receptor full antagonism. |
2009-11-10 |
2023-08-12 |
rat |
| Hidehiro Oshibuchi, Ken Inada, Hiroko Sugawara, Jun Ishigook. Aripiprazole and haloperidol suppress excessive dopamine release in the amygdala in response to conditioned fear stress, but show contrasting effects on basal dopamine release in methamphetamine-sensitized rats. European journal of pharmacology. vol 615. issue 1-3. 2009-11-10. PMID:19477171. |
in the present study, we found that aripiprazole and haloperidol equally suppressed the marked increase in extracellular dopamine levels in fear-conditioned rats, whereas haloperidol increased and aripiprazole decreased tonic dopamine levels. |
2009-11-10 |
2023-08-12 |
rat |
| Hidehiro Oshibuchi, Ken Inada, Hiroko Sugawara, Jun Ishigook. Aripiprazole and haloperidol suppress excessive dopamine release in the amygdala in response to conditioned fear stress, but show contrasting effects on basal dopamine release in methamphetamine-sensitized rats. European journal of pharmacology. vol 615. issue 1-3. 2009-11-10. PMID:19477171. |
in addition, the contrasting effects of haloperidol and aripiprazole on tonic dopamine levels in the amygdala are likely due to the difference in their actions (selective dopamine d(2) receptor full antagonist vs. partial agonist, respectively). |
2009-11-10 |
2023-08-12 |
rat |
| Callie A M Clark, Lori-Ann R Sacrey, Ian Q Whisha. Righting elicited by novel or familiar auditory or vestibular stimulation in the haloperidol-treated rat: rat posturography as a model to study anticipatory motor control. Journal of neuroscience methods. vol 182. issue 2. 2009-10-23. PMID:19559052. |
in the rat, akinetic catalepsy induced by a dopamine d2 receptor antagonist (haloperidol 5mg/kg) can model human catalepsy. |
2009-10-23 |
2023-08-12 |
human |
| Amira Taman, Paula Ribeir. Investigation of a dopamine receptor in Schistosoma mansoni: functional studies and immunolocalization. Molecular and biochemical parasitology. vol 168. issue 1. 2009-10-16. PMID:19545592. |
pharmacological studies showed that the s. mansoni dopamine receptor was inhibited by apomorphine, a classical dopamine agonist, as well as known dopaminergic antagonists, including chlorpromazine, spiperone and haloperidol. |
2009-10-16 |
2023-08-12 |
Not clear |
| Heli Tuppurainen, Jyrki T Kuikka, Heimo Viinamäki, Minna Husso, Jari Tiihone. Dopamine D2/3 receptor binding potential and occupancy in midbrain and temporal cortex by haloperidol, olanzapine and clozapine. Psychiatry and clinical neurosciences. vol 63. issue 4. 2009-10-13. PMID:19496999. |
dopamine d2/3 receptor binding potential and occupancy in midbrain and temporal cortex by haloperidol, olanzapine and clozapine. |
2009-10-13 |
2023-08-12 |
Not clear |
| Aurélien Pichon, Bai Zhenzhong, Fabrice Favret, Guoen Jin, Han Shufeng, Dominique Marchant, Jean-Paul Richalet, Ri-Li G. Long-term ventilatory adaptation and ventilatory response to hypoxia in plateau pika (Ochotona curzoniae): role of nNOS and dopamine. American journal of physiology. Regulatory, integrative and comparative physiology. vol 297. issue 4. 2009-10-13. PMID:19641133. |
we evaluated the role of neuronal nitric oxide synthase (nnos) and dopamine by using s-methyl-l-thiocitrulline (smtc) inhibitor and haloperidol antagonist, respectively. |
2009-10-13 |
2023-08-12 |
rat |
| Michael J Frank, Randall C O'Reill. A mechanistic account of striatal dopamine function in human cognition: psychopharmacological studies with cabergoline and haloperidol. Behavioral neuroscience. vol 120. issue 3. 2009-09-30. PMID:16768602. |
a mechanistic account of striatal dopamine function in human cognition: psychopharmacological studies with cabergoline and haloperidol. |
2009-09-30 |
2023-08-12 |
human |
| Michael J Frank, Randall C O'Reill. A mechanistic account of striatal dopamine function in human cognition: psychopharmacological studies with cabergoline and haloperidol. Behavioral neuroscience. vol 120. issue 3. 2009-09-30. PMID:16768602. |
the authors test a neurocomputational model of dopamine function in cognition by administering to healthy participants low doses of d2 agents cabergoline and haloperidol. |
2009-09-30 |
2023-08-12 |
human |
| Rita C Carvalho, Daniela F Fukushiro, Daniel C Helfer, Donato Callegaro-Filho, Thaís F Trombin, Lineane H F Zanlorenci, Leandro Sanday, Regina H Silva, Roberto Frussa-Filh. Long-term haloperidol treatment (but not risperidone) enhances addiction-related behaviors in mice: role of dopamine D2 receptors. Addiction biology. vol 14. issue 3. 2009-09-24. PMID:19298320. |
long-term haloperidol treatment (but not risperidone) enhances addiction-related behaviors in mice: role of dopamine d2 receptors. |
2009-09-24 |
2023-08-12 |
mouse |
| V Turijski, A Krustev, D Getova-Spassova, V Spasso. Influence of tacrine on dopamine-induced reactions of the gastric smooth muscle of rats. Methods and findings in experimental and clinical pharmacology. vol 26. issue 2. 2009-09-15. PMID:15071608. |
dopamine and d(2)-receptor antagonists haloperidol and r121 had no effect on tacrine-induced relaxation. |
2009-09-15 |
2023-08-12 |
rat |
| Susanne Nikolaus, Christina Antke, Konstantin Kley, Markus Beu, Andreas Wirrwar, Hans-Wilhelm Mülle. Pretreatment with haloperidol reduces (123)I-FP-CIT binding to the dopamine transporter in the rat striatum: an in vivo imaging study with a dedicated small-animal SPECT camera. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 50. issue 7. 2009-09-15. PMID:19525450. |
pretreatment with haloperidol reduces (123)i-fp-cit binding to the dopamine transporter in the rat striatum: an in vivo imaging study with a dedicated small-animal spect camera. |
2009-09-15 |
2023-08-12 |
rat |
| Susanne Nikolaus, Christina Antke, Konstantin Kley, Markus Beu, Andreas Wirrwar, Hans-Wilhelm Mülle. Pretreatment with haloperidol reduces (123)I-FP-CIT binding to the dopamine transporter in the rat striatum: an in vivo imaging study with a dedicated small-animal SPECT camera. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 50. issue 7. 2009-09-15. PMID:19525450. |
the effect of haloperidol, which increases synaptic dopamine concentrations, was therefore assessed in the rat striatum using (123)i-n-omega-fluoropropyl-2beta-carbomethoxy-3beta-(4-iodophenyl)-nortropane ((123)i-fp-cit) as a dat radioligand. |
2009-09-15 |
2023-08-12 |
rat |