| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takaaki Matsuo, Yasuhiko Izumi, Seiko Wakita, Toshiaki Kume, Yuki Takada-Takatori, Hideyuki Sawada, Akinori Akaik. Haloperidol, spiperone, pimozide and aripiprazole reduce intracellular dopamine content in PC12 cells and rat mesencephalic cultures: Implication of inhibition of vesicular transport. European journal of pharmacology. vol 640. issue 1-3. 2010-10-04. PMID:20460122. |
in addition, haloperidol, spiperone, pimozide, aripiprazole and risperidone reduced intracellular dopamine content in a concentration-dependent manner. |
2010-10-04 |
2023-08-12 |
rat |
| Takaaki Matsuo, Yasuhiko Izumi, Seiko Wakita, Toshiaki Kume, Yuki Takada-Takatori, Hideyuki Sawada, Akinori Akaik. Haloperidol, spiperone, pimozide and aripiprazole reduce intracellular dopamine content in PC12 cells and rat mesencephalic cultures: Implication of inhibition of vesicular transport. European journal of pharmacology. vol 640. issue 1-3. 2010-10-04. PMID:20460122. |
instead, haloperidol, spiperone, pimozide and aripiprazole as well as reserpine transiently increased extracellular levels of dopamine metabolites. |
2010-10-04 |
2023-08-12 |
rat |
| Takaaki Matsuo, Yasuhiko Izumi, Seiko Wakita, Toshiaki Kume, Yuki Takada-Takatori, Hideyuki Sawada, Akinori Akaik. Haloperidol, spiperone, pimozide and aripiprazole reduce intracellular dopamine content in PC12 cells and rat mesencephalic cultures: Implication of inhibition of vesicular transport. European journal of pharmacology. vol 640. issue 1-3. 2010-10-04. PMID:20460122. |
in addition, haloperidol, spiperone, pimozide, aripiprazole and risperidone reduced vesicular [3h]dopamine transport. |
2010-10-04 |
2023-08-12 |
rat |
| Takaaki Matsuo, Yasuhiko Izumi, Seiko Wakita, Toshiaki Kume, Yuki Takada-Takatori, Hideyuki Sawada, Akinori Akaik. Haloperidol, spiperone, pimozide and aripiprazole reduce intracellular dopamine content in PC12 cells and rat mesencephalic cultures: Implication of inhibition of vesicular transport. European journal of pharmacology. vol 640. issue 1-3. 2010-10-04. PMID:20460122. |
these results suggest that the inhibition of vesicular dopamine transport by haloperidol, spiperone, pimozide and aripiprazole results in a reduction in vesicular dopamine content. |
2010-10-04 |
2023-08-12 |
rat |
| Ricardo W Binfaré, Michela Mantovani, Josiane Budni, Adair Roberto S Santos, Ana Lúcia S Rodrigue. Involvement of dopamine receptors in the antidepressant-like effect of melatonin in the tail suspension test. European journal of pharmacology. vol 638. issue 1-3. 2010-09-27. PMID:20406627. |
was prevented by the pretreatment of mice with haloperidol (0.2mg/kg, i.p., a nonselective dopaminergic receptor antagonist), sch23390 (0.05 mg/kg, s.c., a selective dopamine d1 receptor antagonist), and sulpiride (50mg/kg, i.p., a selective dopamine d2 receptor antagonist). |
2010-09-27 |
2023-08-12 |
mouse |
| Johnique Billups, Cynthia Jones, Tanise L Jackson, Seth Y Ablordeppey, Shawn D Spence. Simultaneous RP-HPLC-DAD quantification of bromocriptine, haloperidol and its diazepane structural analog in rat plasma with droperidol as internal standard for application to drug-interaction pharmacokinetics. Biomedical chromatography : BMC. vol 24. issue 7. 2010-09-17. PMID:19908205. |
a simple and rapid rp-hplc-dad method was developed and validated for simultaneous determination of the dopamine antagonists haloperidol, its diazepane analog, and the dopamine agonist bromocriptine in rat plasma, to perform pharmacokinetic drug-interaction studies. |
2010-09-17 |
2023-08-12 |
rat |
| Francesco Napolitano, Alessandra Bonito-Oliva, Mauro Federici, Manolo Carta, Francesco Errico, Salvatore Magara, Giuseppina Martella, Robert Nisticò, Diego Centonze, Antonio Pisani, Howard H Gu, Nicola B Mercuri, Alessandro Usiell. Role of aberrant striatal dopamine D1 receptor/cAMP/protein kinase A/DARPP32 signaling in the paradoxical calming effect of amphetamine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 33. 2010-09-03. PMID:20720111. |
such biochemical alteration selectively affected dopamine d(1)rs since haloperidol, by blocking the tonic inhibition of d(2)r, unmasked a normal activation of striatal adenosine a(2a) receptor-mediated camp/pka/darpp32 cascade in mutants. |
2010-09-03 |
2023-08-12 |
mouse |
| Philip Seema. Dopamine D2 receptors as treatment targets in schizophrenia. Clinical schizophrenia & related psychoses. vol 4. issue 1. 2010-09-02. PMID:20643630. |
although antipsychotics such as haloperidol alleviate psychosis and reverse the elevation of d2high receptors, long-term use of traditional antipsychotics can further enhance dopamine supersensitivity in patients. |
2010-09-02 |
2023-08-12 |
Not clear |
| Shuichi Hiraoka, Yasushi Kajii, Yasukazu Kuroda, Asami Umino, Toru Nishikaw. The development- and phencyclidine-regulated induction of synapse-associated protein-97 gene in the rat neocortex. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 20. issue 3. 2010-08-31. PMID:19836928. |
the upregulation of the sap97 transcripts in the adult neocortex after the acute pcp injection was mimicked by another nmda antagonist, dizocilpine, but not by the indirect dopamine agonists, methamphetamine and cocaine, a selective d1 receptor antagonist sch23390, a d2 receptor-preferring antagonist haloperidol and a gabaergic anesthetic pentobarbital. |
2010-08-31 |
2023-08-12 |
rat |
| Hidehiro Oshibuchi, Ken Inada, Jun Ishigook. [Action of amygdala dopamine and effect of antipsychotics]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 30. issue 2. 2010-08-03. PMID:20491283. |
aripiprazole and haloperidol equally suppressed the marked increase in extracellular dopamine levels in fear-conditioned rats, whereas haloperidol increased and aripiprazole decreased basal dopamine levels. |
2010-08-03 |
2023-08-12 |
rat |
| Johan Spoov, Per-Erik Bredbacka, Ulf-Håkan Stenma. An abnormal relation between basal prolactin levels and prolactin response to 12.5 microg TRH i.v. in drug-naïve patients with first-episode schizophrenia. Schizophrenia research. vol 119. issue 1-3. 2010-07-30. PMID:20347273. |
haloperidol and negatively with 24-h urinary excretion of hva in normal subjects, suggesting that the response reflects dopamine activity. |
2010-07-30 |
2023-08-12 |
human |
| Taleen Der-Ghazarian, Sergios Charntikov, Fausto A Varela, Cynthia A Crawford, Sanders A McDougal. Effects of repeated and acute aripiprazole or haloperidol treatment on dopamine synthesis in the dorsal striatum of young rats: comparison to adult rats. Journal of neural transmission (Vienna, Austria : 1996). vol 117. issue 5. 2010-07-29. PMID:20372943. |
effects of repeated and acute aripiprazole or haloperidol treatment on dopamine synthesis in the dorsal striatum of young rats: comparison to adult rats. |
2010-07-29 |
2023-08-12 |
rat |
| Taleen Der-Ghazarian, Sergios Charntikov, Fausto A Varela, Cynthia A Crawford, Sanders A McDougal. Effects of repeated and acute aripiprazole or haloperidol treatment on dopamine synthesis in the dorsal striatum of young rats: comparison to adult rats. Journal of neural transmission (Vienna, Austria : 1996). vol 117. issue 5. 2010-07-29. PMID:20372943. |
the purpose of the present study was to determine whether repeated treatment with the d2 partial agonist aripiprazole or the d2 antagonist haloperidol alters dopamine (da) synthesis characteristics in the dorsal striatum of young rats. |
2010-07-29 |
2023-08-12 |
rat |
| Esther Castillo-Gómez, María Angeles Gómez-Climent, Emilio Varea, Ramón Guirado, José Miguel Blasco-Ibáñez, Carlos Crespo, Francisco José Martínez-Guijarro, Juan Náche. Dopamine acting through D2 receptors modulates the expression of PSA-NCAM, a molecule related to neuronal structural plasticity, in the medial prefrontal cortex of adult rats. Experimental neurology. vol 214. issue 1. 2010-07-21. PMID:18718470. |
in order to evaluate the effects of dopamine in neuronal structural plasticity and on inhibitory neurotransmission, we have analyzed the expression of synaptophysin, psa-ncam and gad67 in the mpfc after cortical dopamine depletion with 6-ohda and after chronic treatments with the d2 receptor antagonist haloperidol or the d2 receptor agonist ppht. |
2010-07-21 |
2023-08-12 |
rat |
| Daniel L Villeneuve, Natàlia Garcia-Reyero, Dalma Martinović, Nathaniel D Mueller, Jenna E Cavallin, Elizabeth J Durhan, Elizabeth A Makynen, Kathleen M Jensen, Michael D Kahl, Lindsey S Blake, Edward J Perkins, Gerald T Ankle. I. Effects of a dopamine receptor antagonist on fathead minnow, Pimephales promelas, reproduction. Ecotoxicology and environmental safety. vol 73. issue 4. 2010-07-16. PMID:19783049. |
this study is the first to apply the fathead minnow 21 d reproduction assay developed for the us endocrine disruptor screening program to evaluate the reproductive toxicity of a model neuroendocrine active chemical, the dopamine 2 receptor antagonist, haloperidol. |
2010-07-16 |
2023-08-12 |
Not clear |
| Daniel L Villeneuve, Natàlia Garcia-Reyero, Dalma Martinović, Nathaniel D Mueller, Jenna E Cavallin, Elizabeth J Durhan, Elizabeth A Makynen, Kathleen M Jensen, Michael D Kahl, Lindsey S Blake, Edward J Perkins, Gerald T Ankle. II: Effects of a dopamine receptor antagonist on fathead minnow dominance behavior and ovarian gene expression in the fathead minnow and zebrafish. Ecotoxicology and environmental safety. vol 73. issue 4. 2010-07-16. PMID:19896709. |
a companion study with the dopamine 2 receptor antagonist, haloperidol, found no evidence of a direct effect of the chemical on fish reproduction. |
2010-07-16 |
2023-08-12 |
zebrafish |
| L N Muranova, V V Andrianov, Kh L Gainutdino. Effect of neuroleptic haloperidol, L-DOPA precursor dopamine, and neurotoxic dopamine analog 6-OHDA on acquisition of conditioned defensive reflex in edible snail. Bulletin of experimental biology and medicine. vol 148. issue 5. 2010-07-09. PMID:20396784. |
effect of neuroleptic haloperidol, l-dopa precursor dopamine, and neurotoxic dopamine analog 6-ohda on acquisition of conditioned defensive reflex in edible snail. |
2010-07-09 |
2023-08-12 |
Not clear |
| L N Muranova, V V Andrianov, Kh L Gainutdino. Effect of neuroleptic haloperidol, L-DOPA precursor dopamine, and neurotoxic dopamine analog 6-OHDA on acquisition of conditioned defensive reflex in edible snail. Bulletin of experimental biology and medicine. vol 148. issue 5. 2010-07-09. PMID:20396784. |
the effect of neuroleptic haloperidol, a dopamine precursor l-dopa, and dopamine analog 6-ohda on the development of conditioned defensive reflex was studied in edible snails. |
2010-07-09 |
2023-08-12 |
Not clear |
| Xavier López-Gil, Francesc Artigas, Albert Adel. Unraveling monoamine receptors involved in the action of typical and atypical antipsychotics on glutamatergic and serotonergic transmission in prefrontal cortex. Current pharmaceutical design. vol 16. issue 5. 2010-06-25. PMID:19909228. |
in the present work, we used in vivo microdialysis to examine: first, the effects of mk-801, on the efflux of glutamate and serotonin (5-ht) in the medial prefrontal cortex (mpfc) of the rat; second, whether the mk-801-induced changes in the cortical efflux of both transmitters could be blocked by atypical (clozapine and olanzapine) and classical (haloperidol and chlorpromazine) antipsychotic drugs given intra-mpfc; and third, the role of local blockade of dopamine d(2)/d(3)/d(4), serotonin 5-ht(2a) and alpha(1)-adrenergic receptors as well as agonism at dopamine d(1)/d(5) and 5-ht(1a) receptors in the mpfc on the increased efflux of glutamate and 5-ht elicited by mk-801. |
2010-06-25 |
2023-08-12 |
rat |
| Nafissa Ismail, Clemence Laroche, Fabienne Girard-Bériault, Shann Ménard, Jonathan A Greggain-Mohr, James G Pfau. Conditioned ejaculatory preference in male rats paired with haloperidol-treated females. Physiology & behavior. vol 100. issue 2. 2010-06-24. PMID:20159027. |
experiment 1 investigated the effect of administering a range of doses of haloperidol, a dopamine d2-receptor antagonist, to females, on female and male sexual behavior. |
2010-06-24 |
2023-08-12 |
rat |