Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
T Arima, J Makihata, T Makimura, Y Nomura, T Segaw. Effects of zotepine, chlorpromazine and haloperidol on D-1, D-2, D-3 and D-4 subtypes of dopamine receptors in rat striatal and bovine caudate nucleus membranes. Neurochemistry international. vol 8. issue 4. 2012-10-02. PMID:20493089. |
effects of zotepine, chlorpromazine and haloperidol on d-1, d-2, d-3 and d-4 subtypes of dopamine receptors in rat striatal and bovine caudate nucleus membranes. |
2012-10-02 |
2023-08-12 |
rat |
T Arima, J Makihata, T Makimura, Y Nomura, T Segaw. Effects of zotepine, chlorpromazine and haloperidol on D-1, D-2, D-3 and D-4 subtypes of dopamine receptors in rat striatal and bovine caudate nucleus membranes. Neurochemistry international. vol 8. issue 4. 2012-10-02. PMID:20493089. |
inhibitory effects of zotepine (zot) on d-1, d-2, d-3 and d-4 subtypes of dopamine (da) receptors were investigated in crude synaptic membranes of rat striatum and bovine caudate nucleus and compared to those of chlorpromazine (cpz) and haloperidol (hal). |
2012-10-02 |
2023-08-12 |
rat |
L F Agnati, K Fuxe, M Ruggeri, E Merlo Pich, F Benfenati, V Volterra, U Ungerstedt, I Zin. Effects of chronic treatment with uridine on striatal dopamine release and dopamine related behaviours in the absence or the presence of chronic treatment with haloperidol. Neurochemistry international. vol 15. issue 1. 2012-10-02. PMID:20504471. |
effects of chronic treatment with uridine on striatal dopamine release and dopamine related behaviours in the absence or the presence of chronic treatment with haloperidol. |
2012-10-02 |
2023-08-12 |
rat |
L F Agnati, K Fuxe, M Ruggeri, E Merlo Pich, F Benfenati, V Volterra, U Ungerstedt, I Zin. Effects of chronic treatment with uridine on striatal dopamine release and dopamine related behaviours in the absence or the presence of chronic treatment with haloperidol. Neurochemistry international. vol 15. issue 1. 2012-10-02. PMID:20504471. |
following 1 week of wash-out, the effects of these treatments on basal striatal dopamine (da) release as well as on the da release induced by an acute haloperidol challenge (2mg/kg, i.p.) |
2012-10-02 |
2023-08-12 |
rat |
M Thereza, R Perez, B Ehinge. Multiple neurotransmitter systems influence the release of adenosine derivatives from the rabbit retina. Neurochemistry international. vol 15. issue 4. 2012-10-02. PMID:20504514. |
dopamine elicited an increase in the release which was partially reduced in a ca(2+)-free medium and was blocked by haloperidol. |
2012-10-02 |
2023-08-12 |
rabbit |
Eric Promme. Role of haloperidol in palliative medicine: an update. The American journal of hospice & palliative care. vol 29. issue 4. 2012-10-02. PMID:21998445. |
haloperidol is a butyrophenone neuroleptic agent characterized as a high-affinity dopamine antagonist, originally used for the treatment of schizophrenia. |
2012-10-02 |
2023-08-12 |
Not clear |
Eric Promme. Role of haloperidol in palliative medicine: an update. The American journal of hospice & palliative care. vol 29. issue 4. 2012-10-02. PMID:21998445. |
awareness of the role dopamine plays in many symptoms in palliative care, such as nausea, vomiting, and delirium, has led to the use of dopamine antagonists such as haloperidol for the treatment of these symptoms in the palliative care setting. |
2012-10-02 |
2023-08-12 |
Not clear |
C Reavill, I P Stolerma. Interaction of nicotine with dopaminergic mechanisms assessed through drug discrimination and rotational behaviour in rats. Journal of psychopharmacology (Oxford, England). vol 1. issue 4. 2012-10-02. PMID:22159140. |
the dopamine antagonists haloperidol and sch 23390 attenuated the discriminative stimulus effect of nicotine and reduced overall rates of responding. |
2012-10-02 |
2023-08-12 |
rat |
Huiliang Dai, R J Care. Behavioural interaction between the NMDA antagonist MK-801 and the dopaminergic antagonist haloperidol: support for a balance model. Journal of psychopharmacology (Oxford, England). vol 9. issue 1. 2012-10-02. PMID:22298687. |
this cancellation effect could not be ascribed to direct drug interference effects on dopamine metabolism since the ex vivo biochemical data revealed that the combined mk-801/haloperidol (0.3/0.5 mg/kg) treatment increased dopamine metabolism to the same extent as haloperidol given alone. |
2012-10-02 |
2023-08-12 |
rat |
William Winlow, Louise Profit, Paul Chris. Aripiprazole: the evidence of its therapeutic impact in schizophrenia. Core evidence. vol 1. issue 4. 2012-10-02. PMID:22496680. |
the dopamine partial agonist aripiprazole is compared with this ideal and with conventional antipsychotics, such as haloperidol, and with atypical antipsychotics. |
2012-10-02 |
2023-08-12 |
Not clear |
Nicole Y L Oei, Serge Arb Rombouts, Roelof P Soeter, Joop M van Gerven, Stephanie Bot. Dopamine modulates reward system activity during subconscious processing of sexual stimuli. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 7. 2012-09-21. PMID:22395731. |
young healthy males (n=53) were randomly assigned to two experimental groups or a control group, and were administered a dopamine antagonist (haloperidol), a dopamine agonist (levodopa), or placebo. |
2012-09-21 |
2023-08-12 |
Not clear |
M A Cheĭdo, M M Gevorgia. [Role of dopamine D1- and D2-receptors in the delta1-opioidergic immunostimulation]. Vestnik Rossiiskoi akademii meditsinskikh nauk. issue 5. 2012-09-19. PMID:22856169. |
sch-23390 (1 mg/kg), a selective antagonist of the postsynaptic dopamine d1-receptors, and selective d2-blocker haloperidol (1 mg/kg) prevented immunostimulating effect of dpdpe. |
2012-09-19 |
2023-08-12 |
mouse |
K P Gudehithlu, A-M Duchemin, G A Tejwani, N H Neff, M Hadjiconstantino. Nicotine-induced changes of brain β-endorphin. Neuropeptides. vol 46. issue 3. 2012-09-12. PMID:22483037. |
the acute effect of nicotine on β-endorphin was reversed by the nicotinic antagonist mecamylamine and the dopamine antagonist haloperidol, indicating pharmacological specificity and involvement of dopamine d2-like receptors. |
2012-09-12 |
2023-08-12 |
Not clear |
Patricia Gassó, Sergi Mas, Oriol Molina, Miquel Bernardo, Amalia Lafuente, Eduard Parellad. Neurotoxic/neuroprotective activity of haloperidol, risperidone and paliperidone in neuroblastoma cells. Progress in neuro-psychopharmacology & biological psychiatry. vol 36. issue 1. 2012-08-20. PMID:21878360. |
haloperidol, risperidone and paliperidone (10, 50, 100 μm) were administered, either alone or in combination with dopamine (100 μm), to human neuroblastoma sk-n-sh. |
2012-08-20 |
2023-08-12 |
human |
Jason M Wiebelhaus, Sarah A Vunck, Herbert Y Meltzer, Joseph H Porte. Discriminative stimulus properties of N-desmethylclozapine, the major active metabolite of the atypical antipsychotic clozapine, in C57BL/6 mice. Behavioural pharmacology. vol 23. issue 3. 2012-08-20. PMID:22547022. |
it was found that the parent drug clozapine fully substituted for ndmc, whereas the typical antipsychotic drug haloperidol (dopamine d2 antagonist) and the atypical antipsychotic drug aripiprazole (d2 partial agonist) did not substitute for ndmc. |
2012-08-20 |
2023-08-12 |
mouse |
S Roux, A M Hay, R D Porsol. Models for assessing antipsychotics: antagonism of amphetamine-induced hyperactivity and stereotypies in mice. Current protocols in pharmacology. vol Chapter 5. 2012-08-03. PMID:21965071. |
all classical antipsychotics, such as chlorpromazine and haloperidol, have potent dopamine receptor-blocking properties. |
2012-08-03 |
2023-08-12 |
mouse |
Davide Amato, Sridhar Natesan, Leonid Yavich, Shitij Kapur, Christian P Mülle. Dynamic regulation of dopamine and serotonin responses to salient stimuli during chronic haloperidol treatment. The international journal of neuropsychopharmacology. vol 14. issue 10. 2012-07-30. PMID:21281560. |
dynamic regulation of dopamine and serotonin responses to salient stimuli during chronic haloperidol treatment. |
2012-07-30 |
2023-08-12 |
human |
Davide Amato, Sridhar Natesan, Leonid Yavich, Shitij Kapur, Christian P Mülle. Dynamic regulation of dopamine and serotonin responses to salient stimuli during chronic haloperidol treatment. The international journal of neuropsychopharmacology. vol 14. issue 10. 2012-07-30. PMID:21281560. |
haloperidol decreased dopamine, but not serotonin baseline levels in a time-dependent way. |
2012-07-30 |
2023-08-12 |
human |
Davide Amato, Sridhar Natesan, Leonid Yavich, Shitij Kapur, Christian P Mülle. Dynamic regulation of dopamine and serotonin responses to salient stimuli during chronic haloperidol treatment. The international journal of neuropsychopharmacology. vol 14. issue 10. 2012-07-30. PMID:21281560. |
short-term haloperidol treatment attenuated the mesolimbic dopamine responses to aversive stimulation, while the responses to appetitive stimulation were largely preserved. |
2012-07-30 |
2023-08-12 |
human |
Davide Amato, Sridhar Natesan, Leonid Yavich, Shitij Kapur, Christian P Mülle. Dynamic regulation of dopamine and serotonin responses to salient stimuli during chronic haloperidol treatment. The international journal of neuropsychopharmacology. vol 14. issue 10. 2012-07-30. PMID:21281560. |
chronic haloperidol treatment, which resembles human d2 receptor occupancy, modulates dopamine and behavioural responses to aversive and appetitive stimulation depending on the duration of treatment. |
2012-07-30 |
2023-08-12 |
human |