| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kwakye Peprah, Xue Y Zhu, Suresh V K Eyunni, Jagan R Etukala, Vincent Setola, Bryan L Roth, Seth Y Ablordeppe. Structure-activity relationship studies of SYA 013, a homopiperazine analog of haloperidol. Bioorganic & medicinal chemistry. vol 20. issue 5. 2013-01-09. PMID:22336245. |
structure-activity relationship studies on 4-(4-(4-chlorophenyl)-1,4-diazepan-1-yl)-1-(4-fluorophenyl)butan-1-one (sya 013), a homopiperazine analog of haloperidol has resulted in an understanding of the effect of structural modifications on binding affinity at dopamine and serotonin receptor subtypes. |
2013-01-09 |
2023-08-12 |
Not clear |
| b' V L Kozlovski\\xc4\\xa. [Effect of haloperidol on changes in development of spontaneous catalepsy during subchronic injections of dopamine agonists and antagonists]. Patologicheskaia fiziologiia i eksperimental\'naia terapiia. issue 3. 2013-01-03. PMID:23072116.' |
[effect of haloperidol on changes in development of spontaneous catalepsy during subchronic injections of dopamine agonists and antagonists]. |
2013-01-03 |
2023-08-12 |
mouse |
| Carla Elena Sartori Oliveira, Bibiana Mozzaquatro Gai, Benhur Godoi, Gilson Zeni, Cristina Wayne Nogueir. The antidepressant-like action of a simple selenium-containing molecule, methyl phenyl selenide, in mice. European journal of pharmacology. vol 690. issue 1-3. 2012-12-17. PMID:22713547. |
in the fst was prevented by pretreatment of mice with haloperidol (0.2 mg/kg, i.p., a dopamine d(2) receptor antagonist), sch 23390 (r-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepine-7-ol) (0.05 mg/kg, s.c., a dopamine d(1) receptor antagonist) and sulpiride (50 mg/kg, i.p., a dopamine d(2) and d(3) antagonist). |
2012-12-17 |
2023-08-12 |
mouse |
| Lyndsey E Collins-Praino, Samantha J Podurgiel, Rotem Kovner, Patrick A Randall, John D Salamon. Extracellular GABA in globus pallidus increases during the induction of oral tremor by haloperidol but not by muscarinic receptor stimulation. Behavioural brain research. vol 234. issue 1. 2012-12-07. PMID:22728308. |
the present studies were undertaken to determine if extracellular levels of gaba in globus pallidus are associated with the induction of tremulous jaw movements by either a dopamine d2 antagonist (haloperidol) or a cholinomimetic (the muscarinic agonist pilocarpine). |
2012-12-07 |
2023-08-12 |
rat |
| N Goldstein, R Goldstein, D Terterov, A A Kamensky, G I Kovalev, Yu A Zolotarev, G N Avakyan, S Tertero. Blood-brain barrier unlocked. Biochemistry. Biokhimiia. vol 77. issue 5. 2012-11-23. PMID:22813582. |
it was studied in two independent experiments: (i) penetration of (3)h-labeled dopamine from its mixture with 10(-5) m h2o2 into hypothalamus and striatum structures of intact rat brain, and (ii) effect of unlabeled dopamine from a mixture with h(2)o(2) on the rat motor activity in a haloperidol catalepsy model. |
2012-11-23 |
2023-08-12 |
rat |
| N Goldstein, R Goldstein, D Terterov, A A Kamensky, G I Kovalev, Yu A Zolotarev, G N Avakyan, S Tertero. Blood-brain barrier unlocked. Biochemistry. Biokhimiia. vol 77. issue 5. 2012-11-23. PMID:22813582. |
it was shown that (i) at the third minute after nasal application of the dopamine + h(2)o(2) mixture, the dopamine level increases 45-fold in the hypothalamus and almost 30-fold in the striatum and (ii) motility of animals in the catalepsy haloperidol model is recovered 90 sec after intranasal introduction of dopamine. |
2012-11-23 |
2023-08-12 |
rat |
| F Li, W Y Cao, M B Li, Y Xu, J W Zhang, J Y Zhang, X G Luo, R P Dai, X F Zhou, C Q L. A simple method for detection of food foraging behavior in the rat: involvement of NMDA and dopamine receptors in the behavior. Neuroscience. vol 205. 2012-11-20. PMID:22244978. |
a dramatic decrease of foraged food was found in the rats after administration of haloperidol (dopamine d2 receptor antagonist) in the competitive, non-competitive, and no-hurdle food foraging tests. |
2012-11-20 |
2023-08-12 |
rat |
| Haiyun Xu, Hong-Ju Yang, Gregory M Ros. Chronic haloperidol-induced spatial memory deficits accompany the upregulation of D(1) and D(2) receptors in the caudate putamen of C57BL/6 mouse. Life sciences. vol 91. issue 9-10. 2012-11-19. PMID:22884478. |
haloperidol (hal) is an antipsychotic drug that has high affinities to the dopamine d(2), but low affinities to d(1) receptors in the brain. |
2012-11-19 |
2023-08-12 |
mouse |
| B B Smith, W C Wagne. Effect of dopamine agonists or antagonists, TRH, stress and piglet removal on plasma prolactin concentrations in lactating gilts. Theriogenology. vol 23. issue 2. 2012-10-02. PMID:16725998. |
the effect of dopamine agonists (ergocryptine), antagonists (chlorpromazine, haloperidol, reserpine, pimozide), thyrotropin releasing hormone or stress (restraint, piglet removal) on prolactin release was studied in primiparous lactating gilts. |
2012-10-02 |
2023-08-12 |
Not clear |
| Francisco Cardos. Sydenham's Chorea. Current treatment options in neurology. vol 10. issue 3. 2012-10-02. PMID:18579027. |
other dopamine receptor-blocking drugs, such as haloperidol, may also be useful. |
2012-10-02 |
2023-08-12 |
Not clear |
| J M Stern, L A Taylo. Haloperidol inhibits maternal retrieval and licking, but enhances nursing behavior and litter weight gains in lactating rats. Journal of neuroendocrinology. vol 3. issue 6. 2012-10-02. PMID:19215528. |
abstract to determine whether the motorically-active and -inactive components of maternal behavior in rats are differentially affected by dopamine, we administered haloperidol, a dopamine receptor antagonist, to lactating rats on day 7 (+/-1) post-partum, 3 h after dam-litter separation and 1 h before their reunion. |
2012-10-02 |
2023-08-12 |
rat |
| J M Stern, L A Taylo. Haloperidol inhibits maternal retrieval and licking, but enhances nursing behavior and litter weight gains in lactating rats. Journal of neuroendocrinology. vol 3. issue 6. 2012-10-02. PMID:19215528. |
compared to treatment with saline or domperidone, a peripherally-active dopamine antagonist, haloperidol treatment inhibited retrieval and licking of pups in a dose-dependent manner and hastened the onset of nursing behavior, but impaired the high crouch posture at the highest doses (8 and 10 mg/kg). |
2012-10-02 |
2023-08-12 |
rat |
| Y Tong, G Pelletie. In vivo Regulation of Prolactin Gene Expression in the Male Rat: Role of Sex Steroids and Dopamine. Journal of neuroendocrinology. vol 3. issue 6. 2012-10-02. PMID:19215533. |
administration of the dopamine d(2) receptor antagonist haloperidol in both intact and orchiectomized rats induced a 4-fold increase in mrna levels. |
2012-10-02 |
2023-08-12 |
rat |
| M E Celis, A J Thody, C Fishe. Effect of Pro-Leu-Gly-NH(2) on plasma levels of ?-MSH in the rat. Neurochemistry international. vol 4. issue 1. 2012-10-02. PMID:20487847. |
since plg also blocked the release of msh induced by the injection of haloperidol, it is suggested that its effect is not mediated by dopamine. |
2012-10-02 |
2023-08-12 |
rat |
| R B Holma. The metabolism of dopamine in rat caudate nucleus can be increased by in vivo "dialysis" perfusion cannulae. Neurochemistry international. vol 7. issue 1. 2012-10-02. PMID:20492914. |
the present studies show that with hplc-ec analysis of the acid metabolites of dopamine (da) and 5-hydroxytryptamine (5-ht) in samples from dialysis cannulae implanted in the caudate nucleus of anaesthetized rats, it is possible to determine the time course of the response of dopamine- and 5-ht containing neurones to administration of monoamine oxidase inhibitors and haloperidol. |
2012-10-02 |
2023-08-12 |
rat |
| T Arima, J Makihata, T Makimura, Y Nomura, T Segaw. Effects of zotepine, chlorpromazine and haloperidol on D-1, D-2, D-3 and D-4 subtypes of dopamine receptors in rat striatal and bovine caudate nucleus membranes. Neurochemistry international. vol 8. issue 4. 2012-10-02. PMID:20493089. |
effects of zotepine, chlorpromazine and haloperidol on d-1, d-2, d-3 and d-4 subtypes of dopamine receptors in rat striatal and bovine caudate nucleus membranes. |
2012-10-02 |
2023-08-12 |
rat |
| T Arima, J Makihata, T Makimura, Y Nomura, T Segaw. Effects of zotepine, chlorpromazine and haloperidol on D-1, D-2, D-3 and D-4 subtypes of dopamine receptors in rat striatal and bovine caudate nucleus membranes. Neurochemistry international. vol 8. issue 4. 2012-10-02. PMID:20493089. |
inhibitory effects of zotepine (zot) on d-1, d-2, d-3 and d-4 subtypes of dopamine (da) receptors were investigated in crude synaptic membranes of rat striatum and bovine caudate nucleus and compared to those of chlorpromazine (cpz) and haloperidol (hal). |
2012-10-02 |
2023-08-12 |
rat |
| L F Agnati, K Fuxe, M Ruggeri, E Merlo Pich, F Benfenati, V Volterra, U Ungerstedt, I Zin. Effects of chronic treatment with uridine on striatal dopamine release and dopamine related behaviours in the absence or the presence of chronic treatment with haloperidol. Neurochemistry international. vol 15. issue 1. 2012-10-02. PMID:20504471. |
effects of chronic treatment with uridine on striatal dopamine release and dopamine related behaviours in the absence or the presence of chronic treatment with haloperidol. |
2012-10-02 |
2023-08-12 |
rat |
| L F Agnati, K Fuxe, M Ruggeri, E Merlo Pich, F Benfenati, V Volterra, U Ungerstedt, I Zin. Effects of chronic treatment with uridine on striatal dopamine release and dopamine related behaviours in the absence or the presence of chronic treatment with haloperidol. Neurochemistry international. vol 15. issue 1. 2012-10-02. PMID:20504471. |
following 1 week of wash-out, the effects of these treatments on basal striatal dopamine (da) release as well as on the da release induced by an acute haloperidol challenge (2mg/kg, i.p.) |
2012-10-02 |
2023-08-12 |
rat |
| M Thereza, R Perez, B Ehinge. Multiple neurotransmitter systems influence the release of adenosine derivatives from the rabbit retina. Neurochemistry international. vol 15. issue 4. 2012-10-02. PMID:20504514. |
dopamine elicited an increase in the release which was partially reduced in a ca(2+)-free medium and was blocked by haloperidol. |
2012-10-02 |
2023-08-12 |
rabbit |