| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ken Inada, Hidehiro Oshibuchi, Jun Shigook. [Significance of the pharmacotherapy of schizophrenia in the emotional context processing of cognition]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 33. issue 3. 2014-09-25. PMID:25069242. |
antipsychotic drugs, such as haloperidol, aripiprazole, and clozapine, suppress this increased release of dopamine in the amygdala in response to conditioned stimuli. |
2014-09-25 |
2023-08-13 |
rat |
| Philip Seema. Clozapine, a fast-off-D2 antipsychotic. ACS chemical neuroscience. vol 5. issue 1. 2014-09-09. PMID:24219174. |
the antipsychotic basis of clozapine is to transiently occupy dopamine d2 receptors in the human striatum, in contrast to haloperidol and chlorpromazine, which have a prolonged occupation of d2 receptors. |
2014-09-09 |
2023-08-12 |
human |
| Dan Madularu, Waqqas M Shams, Wayne G Brak. Estrogen potentiates the behavioral and nucleus accumbens dopamine response to continuous haloperidol treatment in female rats. The European journal of neuroscience. vol 39. issue 2. 2014-09-03. PMID:24164675. |
estrogen potentiates the behavioral and nucleus accumbens dopamine response to continuous haloperidol treatment in female rats. |
2014-09-03 |
2023-08-12 |
rat |
| Dan Madularu, Waqqas M Shams, Wayne G Brak. Estrogen potentiates the behavioral and nucleus accumbens dopamine response to continuous haloperidol treatment in female rats. The European journal of neuroscience. vol 39. issue 2. 2014-09-03. PMID:24164675. |
motor activity was assessed at day 2 and day 12 during haloperidol treatment, while nucleus accumbens dopamine availability was assessed via microdialysis 10 days into antipsychotic treatment. |
2014-09-03 |
2023-08-12 |
rat |
| Flávia Regina Cruz Dias, João Marcos de Mello Bastos, Maria de Fátima Dos Santos Sampaio, Robert J Carey, Marinete Pinheiro Carrer. Opposite effects of typical and atypical anti-psychotic drugs on sensitized dopamine receptors: sub-chronic low dose Olanzapine exposure reverses sensitization but a similar regimen of low dose haloperidol potentiates sensitization effects. Psychopharmacology. vol 230. issue 4. 2014-09-01. PMID:23846543. |
opposite effects of typical and atypical anti-psychotic drugs on sensitized dopamine receptors: sub-chronic low dose olanzapine exposure reverses sensitization but a similar regimen of low dose haloperidol potentiates sensitization effects. |
2014-09-01 |
2023-08-12 |
Not clear |
| Stephen J Winters, Dushan T Ghooray, Rong Q Yang, Joshua B Holmes, Andrew Rw O'Brien, Jay Morgan, Joseph P Moor. Dopamine-2 receptor activation suppresses PACAP expression in gonadotrophs. Endocrinology. vol 155. issue 7. 2014-08-25. PMID:24823390. |
furthermore, blockade of dopamine receptors by injecting haloperidol into newborn rat pups partially reversed the developmental decline in pituitary pacap mrna that occurs between pn1 and pn4. |
2014-08-25 |
2023-08-13 |
rat |
| Patrick Oeckl, Bastian Hengerer, Boris Ferge. G-protein coupled receptor 6 deficiency alters striatal dopamine and cAMP concentrations and reduces dyskinesia in a mouse model of Parkinson's disease. Experimental neurology. vol 257. 2014-08-13. PMID:24747358. |
gpr6(-/-) mice showed higher locomotor activity in the open field, which persisted after treatment with the dopamine d2 receptor antagonist haloperidol. |
2014-08-13 |
2023-08-13 |
mouse |
| Cristiano Termine, Claudia Selvini, Giorgio Rossi, Umberto Balotti. Emerging treatment strategies in Tourette syndrome: what's in the pipeline? International review of neurobiology. vol 112. 2014-07-14. PMID:24295630. |
the most commonly prescribed drugs are dopamine antagonists, such as typical (e.g., haloperidol, pimozide) and atypical neuroleptics (e.g., risperidone, aripiprazole), and α-2-adrenoreceptor agonists (e.g., clonidine). |
2014-07-14 |
2023-08-12 |
Not clear |
| Gregory B Crawford, Meera Agar M, Stephen J Quinn, Jane Phillips, Caroline Litster, Natasha Michael, Matthew Doogue, Debra Rowett, David C Curro. Pharmacovigilance in hospice/palliative care: net effect of haloperidol for delirium. Journal of palliative medicine. vol 16. issue 11. 2014-07-09. PMID:24138282. |
haloperidol, a butyrophenone derivative and dopamine antagonist, is commonly prescribed for nausea, vomiting, and delirium in hospice/palliative care. |
2014-07-09 |
2023-08-12 |
human |
| Ana Caroline Colombo, Amanda Ribeiro de Oliveira, Adriano Edgar Reimer, Marcus Lira Brandã. Dopaminergic mechanisms underlying catalepsy, fear and anxiety: do they interact? Behavioural brain research. vol 257. 2014-06-25. PMID:24120401. |
haloperidol is a dopamine d2 receptor antagonist that induces catalepsy when systemically administered to rodents. |
2014-06-25 |
2023-08-12 |
rat |
| Gil M Lewitus, Horia Pribiag, Rachna Duseja, Michel St-Hilaire, David Stellwage. An adaptive role of TNFα in the regulation of striatal synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 18. 2014-06-23. PMID:24790185. |
striatal tnfα signaling appears to be adaptive in nature, as tnfα is upregulated in response to the prolonged blockade of d2 dopamine receptors and is necessary to reduce the expression of extrapyramidal symptoms induced by chronic haloperidol treatment. |
2014-06-23 |
2023-08-13 |
mouse |
| V G Kolpakov, M A Gilinsky, T A Alekhina, N N Barykina, E M Nikulina, N N Voitenko, A V Kulikov, N I Shtilma. Experimental studies on genetically determined predisposition to catatonia in rats as a model of schizophrenia. Behavioural processes. vol 14. issue 3. 2014-06-14. PMID:24925295. |
the effects of haloperidol and apomorphine on motor activity of cataleptic and normal animals point to a higher sensitivity of postsynaptic dopamine receptors in the former. |
2014-06-14 |
2023-08-13 |
rat |
| D Bury, W J Schmid. Effects of systemically and intrastriatally injected haloperidol and apomorphine on grooming, feeding and locomotion in the rat. Behavioural processes. vol 15. issue 2-3. 2014-06-14. PMID:24925658. |
thus, the sedative effects of peripherally administered haloperidol on locomotion and feeding are not mediated by dopamine in the antero-dorsal striatum. |
2014-06-14 |
2023-08-13 |
rat |
| D Bury, W J Schmid. Effects of systemically and intrastriatally injected haloperidol and apomorphine on grooming, feeding and locomotion in the rat. Behavioural processes. vol 15. issue 2-3. 2014-06-14. PMID:24925658. |
the inhibition of grooming is opposite to the effect of haloperidol and may indicate that dopamine in the antero-dorsal striatum is at least partly involved in a direct control of grooming. |
2014-06-14 |
2023-08-13 |
rat |
| Ulrike Stadlbauer, Wolfgang Langhans, Urs Meye. Administration of the Y2 receptor agonist PYY3-36 in mice induces multiple behavioral changes relevant to schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 12. 2014-06-03. PMID:23748226. |
this effect was fully antagonized by acute treatment with the preferential dopamine d2 receptor antagonist haloperidol, but not with clozapine. |
2014-06-03 |
2023-08-12 |
mouse |
| Jan Booij, Guus van Loon, Kora de Bruin, Pieter Voor. Acute administration of haloperidol does not influence 123I-FP-CIT binding to the dopamine transporter. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 55. issue 4. 2014-06-02. PMID:24604911. |
acute administration of haloperidol does not influence 123i-fp-cit binding to the dopamine transporter. |
2014-06-02 |
2023-08-12 |
rat |
| Jan Booij, Guus van Loon, Kora de Bruin, Pieter Voor. Acute administration of haloperidol does not influence 123I-FP-CIT binding to the dopamine transporter. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 55. issue 4. 2014-06-02. PMID:24604911. |
a recent (123)i-fp-cit ((123)-i-n-ω-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl)nortropane) spect study on rats suggested that a single 1 mg/kg dose of the antipsychotic haloperidol induces enough dopamine release to compete with (123)i-fp-cit for binding to the dopamine transporter. |
2014-06-02 |
2023-08-12 |
rat |
| Kazuhiro Takamats. [Diabetic chorea]. Brain and nerve = Shinkei kenkyu no shinpo. vol 66. issue 2. 2014-05-20. PMID:24523310. |
if the chorea is uncomfortable, disabling, or persistent, symptomatic therapy (e.g., administration of haloperidol, a dopamine antagonist) should be initiated. |
2014-05-20 |
2023-08-12 |
Not clear |
| Natalia Gass, Adam James Schwarz, Alexander Sartorius, Dirk Cleppien, Lei Zheng, Esther Schenker, Celine Risterucci, Andreas Meyer-Lindenberg, Wolfgang Weber-Fah. Haloperidol modulates midbrain-prefrontal functional connectivity in the rat brain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 10. 2014-04-24. PMID:23165219. |
haloperidol induced focal changes in functional connectivity were found to be the most strongly associated with ascending dopamine projections. |
2014-04-24 |
2023-08-12 |
rat |
| Maartje Luijten, Dick J Veltman, Robert Hester, Marion Smits, Ilse M T Nijs, Lolke Pepplinkhuizen, Ingmar H A Franke. The role of dopamine in inhibitory control in smokers and non-smokers: a pharmacological fMRI study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 10. 2014-04-24. PMID:23194834. |
haloperidol (2 mg), a dopamine d2/d3 receptor antagonist, and placebo were administered to 25 smokers and 25 non-smoking controls in a double-blind randomized cross-over design while performing a go/nogo task during fmri scanning. |
2014-04-24 |
2023-08-12 |
Not clear |