Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Masahiko Kawano, Hidehiro Oshibuchi, Takaaki Kawano, Hiroyuki Muraoka, Takahiro Tsutsumi, Makiko Yamada, Ken Inada, Jun Ishigook. Dopamine dynamics during emotional cognitive processing: Implications of the specific actions of clozapine compared with haloperidol. European journal of pharmacology. vol 781. 2017-03-08. PMID:27085900. |
dopamine dynamics during emotional cognitive processing: implications of the specific actions of clozapine compared with haloperidol. |
2017-03-08 |
2023-08-13 |
rat |
Masahiko Kawano, Hidehiro Oshibuchi, Takaaki Kawano, Hiroyuki Muraoka, Takahiro Tsutsumi, Makiko Yamada, Ken Inada, Jun Ishigook. Dopamine dynamics during emotional cognitive processing: Implications of the specific actions of clozapine compared with haloperidol. European journal of pharmacology. vol 781. 2017-03-08. PMID:27085900. |
we also compared how clozapine and haloperidol affected basal dopamine levels and phasic dopamine release in response to the fear-conditioned cue. |
2017-03-08 |
2023-08-13 |
rat |
Masahiko Kawano, Hidehiro Oshibuchi, Takaaki Kawano, Hiroyuki Muraoka, Takahiro Tsutsumi, Makiko Yamada, Ken Inada, Jun Ishigook. Dopamine dynamics during emotional cognitive processing: Implications of the specific actions of clozapine compared with haloperidol. European journal of pharmacology. vol 781. 2017-03-08. PMID:27085900. |
haloperidol treatment increased the baseline dopamine levels in both non-sensitised and sensitised rats. |
2017-03-08 |
2023-08-13 |
rat |
Masahiko Kawano, Hidehiro Oshibuchi, Takaaki Kawano, Hiroyuki Muraoka, Takahiro Tsutsumi, Makiko Yamada, Ken Inada, Jun Ishigook. Dopamine dynamics during emotional cognitive processing: Implications of the specific actions of clozapine compared with haloperidol. European journal of pharmacology. vol 781. 2017-03-08. PMID:27085900. |
although both antipsychotics attenuated phasic dopamine release in both the non-sensitised and sensitised rats, the attenuation extent was greater for clozapine than for haloperidol under both dopaminergic conditions. |
2017-03-08 |
2023-08-13 |
rat |
Joanne C Witsil, Mark B Mycy. Haloperidol, a Novel Treatment for Cannabinoid Hyperemesis Syndrome. American journal of therapeutics. vol 24. issue 1. 2017-02-14. PMID:25393073. |
recent animal data demonstrate complex interactions between dopamine and cannabinoid type 1 signaling, a potential mechanism for haloperidol success in patients with chs. |
2017-02-14 |
2023-08-13 |
Not clear |
Harshal A Fegade, Sudhir N Umath. Immunohistochemical evidence for the involvement of gonadotropin releasing hormone in neuroleptic and cataleptic effects of haloperidol in mice. Neuropeptides. vol 56. 2016-12-21. PMID:26706182. |
blockade of dopamine d2 receptor by haloperidol is attributed for neuroleptic and cataleptic effects; and also for the release of gonadotropin releasing hormone (gnrh) from the hypothalamus. |
2016-12-21 |
2023-08-13 |
mouse |
Shunsuke Yamamoto, Noriyuki Ohta, Atsuhiro Matsumoto, Yu Horiguchi, Moe Koide, Yuji Fujin. Haloperidol Suppresses NF-kappaB to Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Response in RAW 264 Cells. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2016-12-13. PMID:26842661. |
conclusions the data strongly suggest that haloperidol inhibits the immune response by suppressing nf-kb signaling via the dopamine d2 receptor. |
2016-12-13 |
2023-08-13 |
Not clear |
Trayder Thomas, Yu Fang, Elizabeth Yuriev, David K Chalmer. Ligand Binding Pathways of Clozapine and Haloperidol in the Dopamine D2 and D3 Receptors. Journal of chemical information and modeling. vol 56. issue 2. 2016-10-31. PMID:26690887. |
ligand binding pathways of clozapine and haloperidol in the dopamine d2 and d3 receptors. |
2016-10-31 |
2023-08-13 |
Not clear |
Trayder Thomas, Yu Fang, Elizabeth Yuriev, David K Chalmer. Ligand Binding Pathways of Clozapine and Haloperidol in the Dopamine D2 and D3 Receptors. Journal of chemical information and modeling. vol 56. issue 2. 2016-10-31. PMID:26690887. |
we have performed a set of 29 unbiased molecular dynamics simulations to model the binding pathways of the dopamine receptor antagonists clozapine and haloperidol binding to the d2 and d3 dopamine receptors. |
2016-10-31 |
2023-08-13 |
Not clear |
Trayder Thomas, Yu Fang, Elizabeth Yuriev, David K Chalmer. Ligand Binding Pathways of Clozapine and Haloperidol in the Dopamine D2 and D3 Receptors. Journal of chemical information and modeling. vol 56. issue 2. 2016-10-31. PMID:26690887. |
these are the first long time scale simulations of haloperidol or clozapine binding to dopamine receptors. |
2016-10-31 |
2023-08-13 |
Not clear |
Barbara Kosmowska, Jadwiga Wardas, Urszula Głowacka, Subramaniam Ananthan, Krystyna Ossowsk. Pramipexole at a Low Dose Induces Beneficial Effect in the Harmaline-induced Model of Essential Tremor in Rats. CNS neuroscience & therapeutics. vol 22. issue 1. 2016-10-17. PMID:26459182. |
to study receptor mechanisms of these drugs, rats were pretreated with dopamine d3 receptor antagonists--sb-277011-a and sr-21502, an antagonist of presynaptic d2/d3 receptors--amisulpride, or a nonselective antagonist of d2-like receptors, haloperidol, at a postsynaptic dose. |
2016-10-17 |
2023-08-13 |
rat |
Shining Deng, Lingli Zhang, Tailin Zhu, Yan-Mei Liu, Hailong Zhang, Yiping Shen, Wei-Guang Li, Fei L. A behavioral defect of temporal association memory in mice that partly lack dopamine reuptake transporter. Scientific reports. vol 5. 2016-10-13. PMID:26658842. |
interestingly, these temporal association and working memory deficits could be mimicked by a low dose of the dopamine d2 receptor antagonist haloperidol. |
2016-10-13 |
2023-08-13 |
mouse |
Huilin Yang, Yaozeng Xu, Mo Zhu, Ye Gu, Wen Zhang, Hongguo Shao, Yijun Wang, Zichuan Ping, Xuanyang Hu, Liangliang Wang, Dechun Gen. Inhibition of titanium-particle-induced inflammatory osteolysis after local administration of dopamine and suppression of osteoclastogenesis via D2-like receptor signaling pathway. Biomaterials. vol 80. 2016-10-13. PMID:26695376. |
furthermore, the inhibitory effect of dopamine was reversed by the d2-like-receptor antagonist haloperidol but not by the d1-like-receptor antagonist sch23390. |
2016-10-13 |
2023-08-13 |
mouse |
Berenice Venegas-Meneses, José Francisco Padilla, Claudia Elvira Juárez, José Luis Morán, Carolina Morán, Nora Hilda Rosas-Murrieta, Anabella Handal, Roberto Domíngue. Effects of ovarian dopaminergic receptors on ovulation. Endocrine. vol 50. issue 3. 2016-09-26. PMID:26024972. |
the following treatments blocked ovulation: injecting haloperidol to rats on estrus or diestrus-1 at 8:00, 13:00, or 20:00 h and to rats on diestrus-2 at 08:00, or 20:00 h; injecting sch-23390 to rats on diestrus-1 at 8:00, 13:00, or 20:00 h; injecting sulpiride to rats on estrus at 20:00 h, diestrus-1 at 08:00, 13:00, or 20:00 h and to rats on diestrus-2 at 08:00 h. in rats treated with any of the dopamine antagonists that blocked ovulation, injecting gnrh at 14.00 h on the next predicted proestrus day restored ovulation. |
2016-09-26 |
2023-08-13 |
rat |
Nishant S Jain, Lakshyapati Tandi, Lokesh Verm. Contribution of the central histaminergic transmission in the cataleptic and neuroleptic effects of haloperidol. Pharmacology, biochemistry, and behavior. vol 139. issue Pt A. 2016-09-22. PMID:26455279. |
the antipsychotic properties of haloperidol are primarily attributed to its ability to block dopamine d2 receptors. |
2016-09-22 |
2023-08-13 |
rat |
In-Seon Lee, Bombi Lee, Hi-Joon Park, Håkan Olausson, Paul Enck, Younbyoung Cha. A new animal model of placebo analgesia: involvement of the dopaminergic system in reward learning. Scientific reports. vol 5. 2016-09-21. PMID:26602173. |
haloperidol, a dopamine antagonist, blocked these effects in the placebo + haloperidol group. |
2016-09-21 |
2023-08-13 |
Not clear |
J Kregiel, J Golebiowska, P Popik, R Rygul. Dopamine induces an optimism bias in rats-Pharmacological proof for the translational validity of the ambiguous-cue interpretation test. Behavioural brain research. vol 297. 2016-09-15. PMID:26462571. |
to test whether an 'optimistic' bias is also mediated by dopamine in animals, first, two groups of rats received either a dopaminergic precursor, l-dopa, or a d2 receptor antagonist, haloperidol, and were subsequently tested using the ambiguous-cue interpretation (aci) paradigm. |
2016-09-15 |
2023-08-13 |
human |
Yasunori Oda, Shigenori Tadokoro, Masayuki Takase, Nobuhisa Kanahara, Hiroyuki Watanabe, Yukihiko Shirayama, Kenji Hashimoto, Masaomi Iy. G protein-coupled receptor kinase 6/β-arrestin 2 system in a rat model of dopamine supersensitivity psychosis. Journal of psychopharmacology (Oxford, England). vol 29. issue 12. 2016-09-07. PMID:26174132. |
we investigated the effects of chronic continuous treatment with mini-pump-administered haloperidol (hal) on the sensitivity of wistar rats to dopamine, as measured by the locomotor response to methamphetamine (map) and the density of striatal drd2. |
2016-09-07 |
2023-08-13 |
rat |
Renee C Gentzel, Dawn Toolan, Rhonda Roberts, Amy Jo Koser, Monika Kandebo, James Hershey, John J Renger, Jason Uslaner, Sean M Smit. The PDE10A inhibitor MP-10 and haloperidol produce distinct gene expression profiles in the striatum and influence cataleptic behavior in rodents. Neuropharmacology. vol 99. 2016-08-30. PMID:26044638. |
the present study used the selective pde10a inhibitor mp-10 and the dopamine d2 antagonist haloperidol to compare effects of pde10a inhibition and dopamine d2 blockade on striatopallidal (d2) and striatonigral (d1) pathway activation. |
2016-08-30 |
2023-08-13 |
rat |
Mercè Correa, Marta Pardo, Pilar Bayarri, Laura López-Cruz, Noemí San Miguel, Olga Valverde, Catherine Ledent, John D Salamon. Choosing voluntary exercise over sucrose consumption depends upon dopamine transmission: effects of haloperidol in wild type and adenosine A₂AKO mice. Psychopharmacology. vol 233. issue 3. 2016-08-29. PMID:26554387. |
choosing voluntary exercise over sucrose consumption depends upon dopamine transmission: effects of haloperidol in wild type and adenosine a₂ako mice. |
2016-08-29 |
2023-08-13 |
mouse |