| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Makoto Kimura, Yasunori Oda, Kengo Oishi, Kouhei Yoshino, Hiroshi Kimura, Tomihisa Niitsu, Nobuhisa Kanahara, Yukihiko Shirayama, Kenji Hashimoto, Masaomi Iy. Effects of repeated electroconvulsive shocks on dopamine supersensitivity psychosis model rats. Schizophrenia research. vol 228. 2021-06-18. PMID:33429150. |
the objective of this study was to examine whether repeated es can release rats from dopamine supersensitivity states such as striatal dopamine d2 receptor (drd2) up-regulation and voluntary hyperlocomotion following chronic administration of haloperidol (hal). |
2021-06-18 |
2023-08-13 |
rat |
| José Britto-Júnior, David H A Pinheiro, Alberto F O Justo, Guilherme M Figueiredo Murari, Rafael Campos, Fernanda V Mariano, Valéria B de Souza, André A Schenka, Fabiola Z Mónica, Edson Antunes, Gilberto De Nucc. Endothelium-derived dopamine modulates EFS-induced contractions of human umbilical vessels. Pharmacology research & perspectives. vol 8. issue 4. 2021-06-03. PMID:32567793. |
efs studies were performed in the presence and absence of l-name, the α-adrenergic blockers prazosin and idazoxan, and the dopamine antagonists sch-23390 and haloperidol. |
2021-06-03 |
2023-08-13 |
human |
| K Schmack, M Bosc, T Ott, J F Sturgill, A Kepec. Striatal dopamine mediates hallucination-like perception in mice. Science (New York, N.Y.). vol 372. issue 6537. 2021-04-09. PMID:33795430. |
hallucination-like percepts were preceded by elevated striatal dopamine levels, could be induced by optogenetic stimulation of mesostriatal dopamine neurons, and could be reversed by the antipsychotic drug haloperidol. |
2021-04-09 |
2023-08-13 |
mouse |
| Graziela Vieira, Juliana Cavalli, Elaine C D Gonçalves, Saulo F P Braga, Rafaela S Ferreira, Adair R S Santos, Maíra Cola, Nádia R B Raposo, Raffaele Capasso, Rafael C Dutr. Antidepressant-Like Effect of Terpineol in an Inflammatory Model of Depression: Involvement of the Cannabinoid System and D2 Dopamine Receptor. Biomolecules. vol 10. issue 5. 2021-04-02. PMID:32443870. |
moreover, terpineol showed an antidepressant-like effect in the preventive treatment that was blocked by a nonselective dopaminergic receptor antagonist (haloperidol), a selective dopamine d2 receptor antagonist (sulpiride), a selective cb1 cannabinoid receptor antagonist/inverse agonist (am281), and a potent and selective cb2 cannabinoid receptor inverse agonist (am630), but it was not blocked by a nonselective adenosine receptor antagonist (caffeine) or a β-adrenoceptor antagonist (propranolol). |
2021-04-02 |
2023-08-13 |
Not clear |
| Karima Chakroun, David Mathar, Antonius Wiehler, Florian Ganzer, Jan Peter. Dopaminergic modulation of the exploration/exploitation trade-off in human decision-making. eLife. vol 9. 2021-02-22. PMID:32484779. |
thirty-one healthy male participants performed a restless four-armed bandit task in a within-subjects design under three drug conditions: 150 mg of the dopamine precursor l-dopa, 2 mg of the d2 receptor antagonist haloperidol, and placebo. |
2021-02-22 |
2023-08-13 |
human |
| Ben Wagner, Mareike Clos, Tobias Sommer, Jan Peter. Dopaminergic Modulation of Human Intertemporal Choice: A Diffusion Model Analysis Using the D2-Receptor Antagonist Haloperidol. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 41. 2021-01-19. PMID:32948675. |
we previously reported elevated caudate activation under haloperidol in this sample of participants, supporting the idea that haloperidol elevated dopamine neurotransmission (e.g., by blocking inhibitory feedback via presynaptic d2 auto-receptors). |
2021-01-19 |
2023-08-13 |
human |
| Michael Silkstone, Stefan M Brudzynsk. Dissimilar interaction between dopaminergic and cholinergic systems in the initiation of emission of 50-kHz and 22-kHz vocalizations. Pharmacology, biochemistry, and behavior. vol 188. 2020-12-31. PMID:31655084. |
the current study tests the hypothesis that initial antagonism of dopamine receptors by systemic haloperidol or intraacumbens raclopride should increase the subsequent emission of 22 khz usvs induced by carbachol from the lateral septum. |
2020-12-31 |
2023-08-13 |
rat |
| Tibor Stark, Martina Di Bartolomeo, Roberta Di Marco, Eva Drazanova, Chiara Bianca Maria Platania, Fabio Arturo Iannotti, Jana Ruda-Kucerova, Claudio D'Addario, Lucie Kratka, Vladimir Pekarik, Fabiana Piscitelli, Zuzana Babinska, Julia Fedotova, Giovanni Giurdanella, Salvatore Salomone, Alexandra Sulcova, Claudio Bucolo, Carsten T Wotjak, Zenon Starcuk, Filippo Drago, Raphael Mechoulam, Vincenzo Di Marzo, Vincenzo Mical. Altered dopamine D3 receptor gene expression in MAM model of schizophrenia is reversed by peripubertal cannabidiol treatment. Biochemical pharmacology. vol 177. 2020-12-07. PMID:32360362. |
peripubertal treatment with the non-euphoric phytocannabinoid cannabidiol (30 mg/kg) from postnatal day (pnd) 19 to pnd 39 was able to reverse in mam exposed rats: i) the up-regulation of the dopamine d3 receptor mrna (only partially prevented by haloperidol 0.6 mg/kg/day); and ii) the regional blood flow changes in mam exposed rats. |
2020-12-07 |
2023-08-13 |
rat |
| Matthew R Bailey, Eileen Chun, Elke Schipani, Peter D Balsam, Eleanor H Simpso. Dissociating the effects of dopamine D2 receptors on effort-based versus value-based decision making using a novel behavioral approach. Behavioral neuroscience. vol 134. issue 2. 2020-10-30. PMID:32175760. |
we tested the effect of the dopamine d2 receptor antagonist, haloperidol, on performance in the cec and cvc assays and found that d2r signaling is important for effort-based, but not value-based decision making. |
2020-10-30 |
2023-08-13 |
mouse |
| Elisa Guma, Jill Rocchetti, Gabriel A Devenyi, Arnaud Tanti, Axel P Mathieu, Jason P Lerch, Guillaume Elgbeili, Blandine Courcot, Naguib Mechawar, M Mallar Chakravarty, Bruno Giro. Role of D3 dopamine receptors in modulating neuroanatomical changes in response to antipsychotic administration. Scientific reports. vol 9. issue 1. 2020-10-20. PMID:31127135. |
following our previous work, we undertook a longitudinal study to examine the effects of chronic (9-week) typical (haloperidol (hal)) and atypical (clozapine (clz)) apds on the neuroanatomy of wild-type (wt) and dopamine d3-knockout (d3ko) mice using magnetic resonance imaging (mri) and histological assessments in a sub-region of the anterior cingulate cortex (the prelimbic [pl] area) and striatum. |
2020-10-20 |
2023-08-13 |
mouse |
| Rafaela R Silva, Lucas T Parreiras-E-Silva, Thais E T Pompeu, Diego A Duarte, Carlos A M Fraga, Eliezer J Barreiro, Ricardo Menegatti, Claudio M Costa-Neto, François Noë. Evaluation of Functional Selectivity of Haloperidol, Clozapine, and LASSBio-579, an Experimental Compound With Antipsychotic-Like Actions in Rodents, at G Protein and Arrestin Signaling Downstream of the Dopamine D Frontiers in pharmacology. vol 10. 2020-09-29. PMID:31214037. |
evaluation of functional selectivity of haloperidol, clozapine, and lassbio-579, an experimental compound with antipsychotic-like actions in rodents, at g protein and arrestin signaling downstream of the dopamine d lassbio-579, an |
2020-09-29 |
2023-08-13 |
Not clear |
| Jaime Lee, Shane Thwaites, Andrea Gogos, Maarten van den Buus. Pharmacological Mechanisms Involved in Sensory Gating Disruption Induced by (±)-3,4-Methylene- Dioxymethamphetamine (MDMA): Relevance to Schizophrenia. Brain sciences. vol 10. issue 1. 2020-09-28. PMID:31941052. |
pretreatment of the animals with the dopamine d1 receptor antagonist, sch23390, the dopamine d2 receptor antagonist, haloperidol, the serotonin (5-ht)1a receptor antagonist, way100635, or the 5-ht2a receptor antagonist, ketanserin, all blocked the effect of mdma, although the drugs differentially affected the individual s1 and s2 amplitudes. |
2020-09-28 |
2023-08-13 |
rat |
| Abdu Adem, Nather Madjid, Oliver Stiedl, Alessandra Bonito-Oliva, Åsa Konradsson-Geuken, Sarah Holst, Gilberto Fisone, Sven Ove Ögre. Atypical but not typical antipsychotic drugs ameliorate phencyclidine-induced emotional memory impairments in mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 5. 2020-08-07. PMID:30910381. |
the typical apd haloperidol and the dopamine d |
2020-08-07 |
2023-08-13 |
mouse |
| Mareike Clos, Nico Bunzeck, Tobias Somme. Dopamine Enhances Item Novelty Detection via Hippocampal and Associative Recall via Left Lateral Prefrontal Cortex Mechanisms. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 40. 2020-07-02. PMID:31405927. |
better association memory under haloperidol was linked with higher activity in the left lateral prefrontal cortex and right parietal cortex, suggesting that dopamine facilitates associative retrieval through increased recruitment of frontoparietal monitoring processes. |
2020-07-02 |
2023-08-13 |
Not clear |
| Tim J Fyfe, Barrie Kellam, David A Sykes, Ben Capuano, Peter J Scammells, J Robert Lane, Steven J Charlton, Shailesh N Mistr. Structure-Kinetic Profiling of Haloperidol Analogues at the Human Dopamine D Journal of medicinal chemistry. vol 62. issue 21. 2020-06-15. PMID:31580666. |
structure-kinetic profiling of haloperidol analogues at the human dopamine d haloperidol is a typical antipsychotic drug (apd) associated with an increased risk of extrapyramidal side effects (epss) and hyperprolactinemia relative to atypical apds such as clozapine. |
2020-06-15 |
2023-08-13 |
human |
| Sean James Fallon, Kinan Muhammed, Daniel S Drew, Yuen-Siang Ang, Sanjay G Manohar, Masud Husai. Dopamine guides competition for cognitive control: Common effects of haloperidol on working memory and response conflict. Cortex; a journal devoted to the study of the nervous system and behavior. vol 113. 2020-06-08. PMID:30660954. |
dopamine guides competition for cognitive control: common effects of haloperidol on working memory and response conflict. |
2020-06-08 |
2023-08-13 |
Not clear |
| Sean James Fallon, Kinan Muhammed, Daniel S Drew, Yuen-Siang Ang, Sanjay G Manohar, Masud Husai. Dopamine guides competition for cognitive control: Common effects of haloperidol on working memory and response conflict. Cortex; a journal devoted to the study of the nervous system and behavior. vol 113. 2020-06-08. PMID:30660954. |
here, we examine the effect of haloperidol, principally a dopamine d |
2020-06-08 |
2023-08-13 |
Not clear |
| Steven J Shoptaw, Uyen Kao, Walter W Lin. Treatment for amphetamine psychosis. The Cochrane database of systematic reviews. issue 4. 2020-05-11. PMID:18843639. |
it has long been believed that dopamine antagonists, such as chlorpromazine, haloperidol, and thioridazine, are effective for the treatment of amphetamine psychosis. |
2020-05-11 |
2023-08-12 |
Not clear |
| Laura Clara Grandi, Giuseppe Di Giovanni, Salvatore Galat. Reprint of "Animal models of early-stage Parkinson's disease and acute dopamine deficiency to study compensatory neurodegenerative mechanisms". Journal of neuroscience methods. vol 310. 2020-03-30. PMID:30396695. |
here, we reviewed the literature related to animal models of early-stage pd and pharmacological treatments capable of inducing acute dopamine impairments and/or depletion, such as reserpine, haloperidol and tetrodotoxin. |
2020-03-30 |
2023-08-13 |
Not clear |
| Mohammad Moshahid Khan, Jianfeng Xiao, T J Hollingsworth, Damini Patel, Dana E Selley, Trevor L Ring, Mark S LeDou. Gnal haploinsufficiency causes genomic instability and increased sensitivity to haloperidol. Experimental neurology. vol 318. 2020-03-02. PMID:31034808. |
dopamine d2 receptor (d2r) blockers such as haloperidol are mainstays in the treatment of psychosis but may contribute to the development of secondary acute and tardive dystonia. |
2020-03-02 |
2023-08-13 |
Not clear |