| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| José Britto-Júnior, Luiz Ximenes, André Ribeiro, Adriano Fregonesi, Rafael Campos, Luiz Ricardo de Almeida Kiguti, Fabíola Z Mónica, Edson Antunes, Gilberto De Nucc. 6-Nitrodopamine is an endogenous mediator of rat isolated epididymal vas deferens contractions induced by electric-field stimulation. European journal of pharmacology. vol 911. 2021-11-01. PMID:34606837. |
dopamine, noradrenaline, adrenaline and 6-nd levels were quantified in rat isolated vas deferens by lc-ms-ms. electric-field stimulation (efs) and concentration-response curves to 6-nd, noradrenaline, dopamine and adrenaline were performed in the absence and in the presence (30 min) of l-name, sch-23390, haloperidol, pg-01037, sonepiprazole, desipramine, clomipramine, amitriptyline, cyclobenzaprine, carbamazepine, maprotiline, paroxetine, oxcarbazepine and ketanserin in the rat isolated epididymal vas deferens (rievd). |
2021-11-01 |
2023-08-13 |
human |
| José Britto-Júnior, Luiz Ximenes, André Ribeiro, Adriano Fregonesi, Rafael Campos, Luiz Ricardo de Almeida Kiguti, Fabíola Z Mónica, Edson Antunes, Gilberto De Nucc. 6-Nitrodopamine is an endogenous mediator of rat isolated epididymal vas deferens contractions induced by electric-field stimulation. European journal of pharmacology. vol 911. 2021-11-01. PMID:34606837. |
haloperidol, pg-01037 and sonepiprazole caused significant rightward shifts on concentration-response curves to dopamine but had no effect on either the 6-nd or efs-induced rievd contractions. |
2021-11-01 |
2023-08-13 |
human |
| Trisha L Vickrey, B Jill Vento. Drosophila Dopamine2-like receptors function as autoreceptors. ACS chemical neuroscience. vol 2. issue 12. 2021-10-21. PMID:22308204. |
d2 antagonists were expected to increase dopamine release and the d2 antagonists flupenthixol, butaclamol, and haloperidol did increase stimulated release. |
2021-10-21 |
2023-08-12 |
drosophila_melanogaster |
| Alice Servonnet, Florence Allain, Alice Gravel-Chouinard, Giovanni Hernandez, Casey Bourdeau Caporuscio, Mathilde Legrix, Daniel Lévesque, Pierre-Paul Rompré, Anne-Noël Samah. Dopaminergic mechanisms underlying the expression of antipsychotic-induced dopamine supersensitivity in rats. Neuropharmacology. vol 197. 2021-10-14. PMID:34364897. |
finally, after discontinuing haloperidol treatment, neither increasing ventral midbrain dopamine impulse flow nor infusing d-amphetamine into the cerebral ventricles triggered the expression of already established dopamine supersensitivity, suggesting that peripheral effects are required. |
2021-10-14 |
2023-08-13 |
rat |
| Raly James Perez Custodio, Leandro Val Sayson, Chrislean Jun Botanas, Arvie Abiero, Kyung Yi You, Mikyung Kim, Hyun Jun Lee, Sung Yeun Yoo, Kun Won Lee, Yong Sup Lee, Joung-Wook Seo, In Soo Ryu, Hee Jin Kim, Jae Hoon Cheon. 25B-NBOMe, a novel N-2-methoxybenzyl-phenethylamine (NBOMe) derivative, may induce rewarding and reinforcing effects via a dopaminergic mechanism: Evidence of abuse potential. Addiction biology. vol 25. issue 6. 2021-09-28. PMID:31749223. |
pretreatment with sch23390 (sch), haloperidol (hal), and ketanserin (ks), antagonists of dopamine d1 (drd |
2021-09-28 |
2023-08-13 |
Not clear |
| Alexander H Burton, Qing Bai, Edward A Burto. Sinusoidal analysis reveals a non-linear and dopamine-dependent relationship between ambient illumination and motor activity in larval zebrafish. Neuroscience letters. vol 761. 2021-08-27. PMID:34293416. |
at concentrations ≤5 μm, the dopamine d2 receptor inverse agonist haloperidol selectively abrogated the motor response to decreasing illuminance without altering baseline activity in bright light, suggesting that dopamine is essential for illuminance-dependent motor function. |
2021-08-27 |
2023-08-13 |
zebrafish |
| Tuane Bazanella Sampaio, Filipe Neimaier Bilheri, Gilson Rogério Zeni, Cristina Wayne Nogueir. Dopaminergic system contribution to the antidepressant-like effect of 3-phenyl-4-(phenylseleno) isoquinoline in mice. Behavioural brain research. vol 386. 2021-08-24. PMID:32184159. |
lastly, the contribution of dopaminergic system in the psi antidepressant-like effect was demonstrated by using dopamine receptors antagonists, sch23390, haloperidol and sulpiride. |
2021-08-24 |
2023-08-13 |
mouse |
| Avila G, Picazo O, Chuc-Meza E, García-Ramirez . Reduction of dopaminergic transmission in the globus pallidus increases anxiety-like behavior without altering motor activity. Behavioural brain research. vol 386. 2021-08-24. PMID:32194191. |
additionally, the effect on da receptors in the gp was tested by local administration of the dopamine agonist pd168,077, antagonist haloperidol and psychostimulant amphetamine. |
2021-08-24 |
2023-08-13 |
rat |
| Darlene Mae Ortiz, Raly James Perez Custodio, Arvie Abiero, Chrislean Jun Botanas, Leandro Val Sayson, Mikyung Kim, Hyun Jun Lee, Hee Jin Kim, Youngdo Jeong, Sulmin Yoon, Yong Sup Lee, Jae Hoon Cheon. The dopaminergic alterations induced by 4-F-PCP and 4-Keto-PCP may enhance their drug-induced rewarding and reinforcing effects: Implications for abuse. Addiction biology. vol 26. issue 4. 2021-08-16. PMID:33135332. |
dopamine (da) receptor antagonists (sch23390 and haloperidol) were administered during cpp to evaluate the involvement of the mesolimbic dopaminergic system. |
2021-08-16 |
2023-08-13 |
Not clear |
| Makoto Kimura, Yasunori Oda, Hiroshi Kimura, Masahito Nangaku, Yuki Hirose, Tomihisa Niitsu, Nobuhisa Kanahara, Yukihiko Shirayama, Kenji Hashimoto, Masaomi Iy. Reduction of dopamine and glycogen synthase kinase-3 signaling in rat striatum after continuous administration of haloperidol. Pharmacology, biochemistry, and behavior. vol 202. 2021-08-10. PMID:33485878. |
reduction of dopamine and glycogen synthase kinase-3 signaling in rat striatum after continuous administration of haloperidol. |
2021-08-10 |
2023-08-13 |
rat |
| Bárbara Nunes Krum, Airton C Martins, Libânia Queirós, Beatriz Ferrer, Ginger L Milne, Félix Alexandre Antunes Soares, Roselei Fachinetto, Michael Aschne. Haloperidol Interactions with the dop-3 Receptor in Caenorhabditis elegans. Molecular neurobiology. vol 58. issue 1. 2021-08-04. PMID:32935232. |
haloperidol is a typical antipsychotic drug commonly used to treat a broad range of psychiatric disorders related to dysregulations in the neurotransmitter dopamine (da). |
2021-08-04 |
2023-08-13 |
caenorhabditis_elegans |
| Nicole S Lee, Annaliese K Beer. The role of dopamine signaling in prairie vole peer relationships. Hormones and behavior. vol 127. 2021-06-25. PMID:33152338. |
haloperidol blockade of dopamine receptors at multiple doses did not alter selective preferences for familiar same-sex partners, suggesting that dopamine neurotransmission is not necessary for the formation of prairie vole peer relationships, unlike mate relationships. |
2021-06-25 |
2023-08-13 |
Not clear |
| Jochen Michely, Shivakumar Viswanathan, Tobias U Hauser, Laura Delker, Raymond J Dolan, Christian Grefke. The role of dopamine in dynamic effort-reward integration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 9. 2021-06-23. PMID:32268344. |
in a placebo-controlled, within-subject, study, we probed the impact of increasing brain dopamine levels (150 mg of levodopa) and blocking dopamine receptors (1.5 mg of haloperidol) in the context of a novel dynamic effort task in healthy human subjects. |
2021-06-23 |
2023-08-13 |
human |
| Maria De Risi, Michele Tufano, Filomena Grazia Alvino, Maria Grazia Ferraro, Giulia Torromino, Ylenia Gigante, Jlenia Monfregola, Elena Marrocco, Salvatore Pulcrano, Lea Tunisi, Claudia Lubrano, Dulce Papy-Garcia, Yaakov Tuchman, Alberto Salleo, Francesca Santoro, Gian Carlo Bellenchi, Luigia Cristino, Andrea Ballabio, Alessandro Fraldi, Elvira De Leonibu. Altered heparan sulfate metabolism during development triggers dopamine-dependent autistic-behaviours in models of lysosomal storage disorders. Nature communications. vol 12. issue 1. 2021-06-22. PMID:34108486. |
hyperdopaminergia and autistic-like behaviours are corrected by the dopamine d1-like receptor antagonist sch-23390, providing a potential alternative strategy to the d2-like antagonist haloperidol that has only minimal therapeutic effects in mps-iiia. |
2021-06-22 |
2023-08-13 |
mouse |
| Uri Nimrod Ramírez-Jarquín, Neelam Shahani, William Pryor, Alessandro Usiello, Srinivasa Subramania. The mammalian target of rapamycin (mTOR) kinase mediates haloperidol-induced cataleptic behavior. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:33009372. |
here, we have identified that the depletion of the mtor gene in the mice striatum completely prevented the extrapyramidal motor side effects (catalepsy) induced by the dopamine 2 receptor (d2r) antagonist haloperidol, which is the most widely used typical antipsychotic drug. |
2021-06-18 |
2023-08-13 |
mouse |
| Makoto Kimura, Yasunori Oda, Kengo Oishi, Kouhei Yoshino, Hiroshi Kimura, Tomihisa Niitsu, Nobuhisa Kanahara, Yukihiko Shirayama, Kenji Hashimoto, Masaomi Iy. Effects of repeated electroconvulsive shocks on dopamine supersensitivity psychosis model rats. Schizophrenia research. vol 228. 2021-06-18. PMID:33429150. |
the objective of this study was to examine whether repeated es can release rats from dopamine supersensitivity states such as striatal dopamine d2 receptor (drd2) up-regulation and voluntary hyperlocomotion following chronic administration of haloperidol (hal). |
2021-06-18 |
2023-08-13 |
rat |
| José Britto-Júnior, David H A Pinheiro, Alberto F O Justo, Guilherme M Figueiredo Murari, Rafael Campos, Fernanda V Mariano, Valéria B de Souza, André A Schenka, Fabiola Z Mónica, Edson Antunes, Gilberto De Nucc. Endothelium-derived dopamine modulates EFS-induced contractions of human umbilical vessels. Pharmacology research & perspectives. vol 8. issue 4. 2021-06-03. PMID:32567793. |
efs studies were performed in the presence and absence of l-name, the α-adrenergic blockers prazosin and idazoxan, and the dopamine antagonists sch-23390 and haloperidol. |
2021-06-03 |
2023-08-13 |
human |
| K Schmack, M Bosc, T Ott, J F Sturgill, A Kepec. Striatal dopamine mediates hallucination-like perception in mice. Science (New York, N.Y.). vol 372. issue 6537. 2021-04-09. PMID:33795430. |
hallucination-like percepts were preceded by elevated striatal dopamine levels, could be induced by optogenetic stimulation of mesostriatal dopamine neurons, and could be reversed by the antipsychotic drug haloperidol. |
2021-04-09 |
2023-08-13 |
mouse |
| Graziela Vieira, Juliana Cavalli, Elaine C D Gonçalves, Saulo F P Braga, Rafaela S Ferreira, Adair R S Santos, Maíra Cola, Nádia R B Raposo, Raffaele Capasso, Rafael C Dutr. Antidepressant-Like Effect of Terpineol in an Inflammatory Model of Depression: Involvement of the Cannabinoid System and D2 Dopamine Receptor. Biomolecules. vol 10. issue 5. 2021-04-02. PMID:32443870. |
moreover, terpineol showed an antidepressant-like effect in the preventive treatment that was blocked by a nonselective dopaminergic receptor antagonist (haloperidol), a selective dopamine d2 receptor antagonist (sulpiride), a selective cb1 cannabinoid receptor antagonist/inverse agonist (am281), and a potent and selective cb2 cannabinoid receptor inverse agonist (am630), but it was not blocked by a nonselective adenosine receptor antagonist (caffeine) or a β-adrenoceptor antagonist (propranolol). |
2021-04-02 |
2023-08-13 |
Not clear |
| Karima Chakroun, David Mathar, Antonius Wiehler, Florian Ganzer, Jan Peter. Dopaminergic modulation of the exploration/exploitation trade-off in human decision-making. eLife. vol 9. 2021-02-22. PMID:32484779. |
thirty-one healthy male participants performed a restless four-armed bandit task in a within-subjects design under three drug conditions: 150 mg of the dopamine precursor l-dopa, 2 mg of the d2 receptor antagonist haloperidol, and placebo. |
2021-02-22 |
2023-08-13 |
human |