| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alice Servonnet, Ellie-Anna Minogianis, Claude Bouchard, Anne-Marie Bédard, Daniel Lévesque, Pierre-Paul Rompré, Anne-Noël Samah. Neurotensin in the nucleus accumbens reverses dopamine supersensitivity evoked by antipsychotic treatment. Neuropharmacology. vol 123. 2018-05-09. PMID:28522313. |
long-term exposure to antipsychotics like haloperidol can increase sensitivity to dopamine agonist stimulation. |
2018-05-09 |
2023-08-13 |
rat |
| Olivia Engmann, Albert Giralt, Jean-Antoine Giraul. Acute drug-induced spine changes in the nucleus accumbens are dependent on β-adducin. Neuropharmacology. vol 110. issue Pt A. 2018-02-22. PMID:27480796. |
here, we show that spine density and length are increased in the nucleus accumbens 24 h after a single injection of caffeine or quinpirole, a dopamine d2/d3 dopamine receptors agonist, whereas the dopamine antagonist haloperidol has opposite effects. |
2018-02-22 |
2023-08-13 |
mouse |
| R A N Pértile, M E Corvino, R C N Marchette, E Pavesi, J Cavalli, A Ramos, G S Izídi. The Quinpirole Hypolocomotive Effects are Strain and Route of Administration Dependent in SHR and SLA16 Isogenic Rats. Behavior genetics. vol 47. issue 5. 2018-02-05. PMID:28822047. |
haloperidol vhip did not elicit behavioural changes and no differences in the levels of d2 receptors and of dopamine transporter in the hippocampus were found. |
2018-02-05 |
2023-08-13 |
rat |
| Kazunori Suzuki, Akina Harada, Hirobumi Suzuki, Maki Miyamoto, Haruhide Kimur. TAK-063, a PDE10A Inhibitor with Balanced Activation of Direct and Indirect Pathways, Provides Potent Antipsychotic-Like Effects in Multiple Paradigms. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 9. 2018-01-09. PMID:26849714. |
however, excess activation of the direct pathway by a dopamine d1 receptor agonist skf82958 canceled antipsychotic-like effects of a dopamine d2 receptor antagonist haloperidol in methamphetamine (meth)-induced hyperactivity in rats. |
2018-01-09 |
2023-08-13 |
rat |
| Joanna Golebiowska, Rafal Rygul. Effects of acute dopaminergic and serotonergic manipulations in the ACI paradigm depend on the basal valence of cognitive judgement bias in rats. Behavioural brain research. vol 327. 2017-12-19. PMID:28212943. |
to test whether dopamine might play a similar role in non-human animals, in the present study, we evaluated the effects of acute injections of l-dopa, the d2 receptor antagonist haloperidol, and the ssri escitalopram on cognitive judgement bias of rats in the ambiguous-cue interpretation (aci) paradigm. |
2017-12-19 |
2023-08-13 |
rat |
| Samantha E Yohn, Daniela Alberati, Merce Correa, John D Salamon. Assessment of a glycine uptake inhibitor in animal models of effort-related choice behavior: implications for motivational dysfunctions. Psychopharmacology. vol 234. issue 9-10. 2017-12-13. PMID:28083675. |
interference with dopamine (da) transmission by administration of the da d2 family antagonist haloperidol biases behavior towards the lower effort option that can be obtained with minimal work, and previous research has shown that da interacts with other transmitters, including adenosine and gaba, to regulate effort-based choice. |
2017-12-13 |
2023-08-13 |
Not clear |
| Regina V Guarnieri, Luciano G Buratto, Carlos F A Gomes, Rafaela L Ribeiro, Altay A Lino de Souza, Lilian M Stein, José C Galduróz, Orlando F A Buen. Haloperidol increases false recognition memory of thematically related pictures in healthy volunteers. Human psychopharmacology. vol 32. issue 1. 2017-11-29. PMID:27925283. |
in a randomized, double-blind, placebo-controlled experiment, 24 young healthy volunteers ingested a 4-mg oral dose of haloperidol, a dopamine d |
2017-11-29 |
2023-08-13 |
human |
| L Lencesova, I Szadvari, P Babula, J Kubickova, B Chovancova, K Lopusna, I Rezuchova, Z Novakova, O Krizanova, M Novakov. Disruption of dopamine D1/D2 receptor complex is involved in the function of haloperidol in cardiac H9c2 cells. Life sciences. vol 191. 2017-11-28. PMID:29054453. |
disruption of dopamine d1/d2 receptor complex is involved in the function of haloperidol in cardiac h9c2 cells. |
2017-11-28 |
2023-08-13 |
Not clear |
| L Lencesova, I Szadvari, P Babula, J Kubickova, B Chovancova, K Lopusna, I Rezuchova, Z Novakova, O Krizanova, M Novakov. Disruption of dopamine D1/D2 receptor complex is involved in the function of haloperidol in cardiac H9c2 cells. Life sciences. vol 191. 2017-11-28. PMID:29054453. |
haloperidol is an antipsychotic agent and acts as dopamine d2 receptor (d2r) antagonist, as a prototypical ligand of sigma1 receptors (sig1r) and it increases expression of type 1 ip |
2017-11-28 |
2023-08-13 |
Not clear |
| Eliyahu Dremencov, Lubica Lacinova, Gunnar Flik, Joost Ha Folgering, Thomas Ifh Cremers, Ben Hc Westerin. Purinergic regulation of brain catecholamine neurotransmission: In vivo electrophysiology and microdialysis study in rats. General physiology and biophysics. vol 36. issue 4. 2017-11-24. PMID:28857746. |
the ability of antagonists of a2a receptors to potentiate the effect of haloperidol on brain norepinephrine and dopamine levels may enhance its clinical efficacy as an antipsychotic drug. |
2017-11-24 |
2023-08-13 |
rat |
| Arthur S C França, Larissa Muratori, George Carlos Nascimento, Catia Mendes Pereira, Sidarta Ribeiro, Bruno Lobão-Soare. Object recognition impairment and rescue by a dopamine D2 antagonist in hyperdopaminergic mice. Behavioural brain research. vol 308. 2017-11-21. PMID:27059337. |
we used a classical dopamine d2 antagonist, haloperidol, to modulate the levels of dopaminergic transmission in a dose-dependent manner, before or after exploring novel objects. |
2017-11-21 |
2023-08-13 |
mouse |
| Tobias Schwalbe, Jonas Kaindl, Harald Hübner, Peter Gmeine. Potent haloperidol derivatives covalently binding to the dopamine D2 receptor. Bioorganic & medicinal chemistry. vol 25. issue 19. 2017-10-16. PMID:28666858. |
potent haloperidol derivatives covalently binding to the dopamine d2 receptor. |
2017-10-16 |
2023-08-13 |
Not clear |
| Vijayapandi Pandy, Megala Narasingam, Kamini Vijeepallam, Syam Mohan, Vasudevan Mani, Zahurin Mohame. The ethyl acetate fraction of a methanolic extract of unripe noni (Morinda citrifolia Linn.) fruit exhibits a biphasic effect on the dopaminergic system in mice. Experimental animals. vol 66. issue 3. 2017-09-28. PMID:28450692. |
), which was evident from alleviation of haloperidol (a dopamine d |
2017-09-28 |
2023-08-13 |
mouse |
| Yan Ke, Wentao Li, Zhiqun Tan, Zhikuan Yan. Induction of dopamine D1 and D5 receptors in R28 cells by light exposures. Biochemical and biophysical research communications. vol 486. issue 3. 2017-06-02. PMID:28336436. |
notably, treatments of r28 cells with nanomolar dosages of dopamine (0-500 nm) directly downregulated expression of both drd1 and drd5, whereas haloperidol (0-50 nm), a drd2 antagonist, significantly induced expression of drd1. |
2017-06-02 |
2023-08-13 |
rat |
| Yasuharu Shinoda, Hideaki Tagashira, Md Shenuarin Bhuiyan, Hideyuki Hasegawa, Hiroshi Kanai, Kohji Fukunag. Haloperidol aggravates transverse aortic constriction-induced heart failure via mitochondrial dysfunction. Journal of pharmacological sciences. vol 131. issue 3. 2017-04-17. PMID:27435383. |
haloperidol is an antipsychotic drug that inhibits the dopamine d2 receptor among others. |
2017-04-17 |
2023-08-13 |
mouse |
| Masahiko Kawano, Hidehiro Oshibuchi, Takaaki Kawano, Hiroyuki Muraoka, Takahiro Tsutsumi, Makiko Yamada, Ken Inada, Jun Ishigook. Dopamine dynamics during emotional cognitive processing: Implications of the specific actions of clozapine compared with haloperidol. European journal of pharmacology. vol 781. 2017-03-08. PMID:27085900. |
dopamine dynamics during emotional cognitive processing: implications of the specific actions of clozapine compared with haloperidol. |
2017-03-08 |
2023-08-13 |
rat |
| Masahiko Kawano, Hidehiro Oshibuchi, Takaaki Kawano, Hiroyuki Muraoka, Takahiro Tsutsumi, Makiko Yamada, Ken Inada, Jun Ishigook. Dopamine dynamics during emotional cognitive processing: Implications of the specific actions of clozapine compared with haloperidol. European journal of pharmacology. vol 781. 2017-03-08. PMID:27085900. |
we also compared how clozapine and haloperidol affected basal dopamine levels and phasic dopamine release in response to the fear-conditioned cue. |
2017-03-08 |
2023-08-13 |
rat |
| Masahiko Kawano, Hidehiro Oshibuchi, Takaaki Kawano, Hiroyuki Muraoka, Takahiro Tsutsumi, Makiko Yamada, Ken Inada, Jun Ishigook. Dopamine dynamics during emotional cognitive processing: Implications of the specific actions of clozapine compared with haloperidol. European journal of pharmacology. vol 781. 2017-03-08. PMID:27085900. |
haloperidol treatment increased the baseline dopamine levels in both non-sensitised and sensitised rats. |
2017-03-08 |
2023-08-13 |
rat |
| Masahiko Kawano, Hidehiro Oshibuchi, Takaaki Kawano, Hiroyuki Muraoka, Takahiro Tsutsumi, Makiko Yamada, Ken Inada, Jun Ishigook. Dopamine dynamics during emotional cognitive processing: Implications of the specific actions of clozapine compared with haloperidol. European journal of pharmacology. vol 781. 2017-03-08. PMID:27085900. |
although both antipsychotics attenuated phasic dopamine release in both the non-sensitised and sensitised rats, the attenuation extent was greater for clozapine than for haloperidol under both dopaminergic conditions. |
2017-03-08 |
2023-08-13 |
rat |
| Joanne C Witsil, Mark B Mycy. Haloperidol, a Novel Treatment for Cannabinoid Hyperemesis Syndrome. American journal of therapeutics. vol 24. issue 1. 2017-02-14. PMID:25393073. |
recent animal data demonstrate complex interactions between dopamine and cannabinoid type 1 signaling, a potential mechanism for haloperidol success in patients with chs. |
2017-02-14 |
2023-08-13 |
Not clear |