| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takashi Hashimoto, Satoko Baba, Hiroko Ikeda, Yasunori Oda, Kenji Hashimoto, Isao Shimiz. Lack of dopamine supersensitivity in rats after chronic administration of blonanserin: Comparison with haloperidol. European journal of pharmacology. vol 830. 2018-09-25. PMID:29684390. |
it is reported that repeated administration of haloperidol caused dopamine supersensitivity in rats. |
2018-09-25 |
2023-08-13 |
rat |
| O M Zherelova, A A Kataev, V M Grischenko, R S Shtanchae. HALOPERIDOL MODULATES IONIC TRANSPORT OF CHARA CORALLINA CELLS. Tsitologiia. vol 58. issue 8. 2018-09-14. PMID:30183213. |
the effect of the haloperidol (hp), a dopamine d2-receptor antagonist on the function of ionic channels ofthe electrically excitable plasma membrane and on the cytoskeleton of chara corallina cells was investigated.haloperidol was shown to block plasmalemmal ca2+ channels. |
2018-09-14 |
2023-08-13 |
Not clear |
| Nobue Kitanaka, Junichi Kitanaka, F Scott Hall, Yoshiro Kubota, Yumi Mimura, Sayaka Ogura, Yukiya Okada, George R Uhl, Motohiko Takemur. Psychotomimetic-like behavioral effects of memantine in the mouse. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 100. 2018-09-03. PMID:29427922. |
memantine-induced stereotyped sniffing was attenuated by pretreatment with haloperidol, a dopamine d |
2018-09-03 |
2023-08-13 |
mouse |
| Jana Kubickova, Lubomira Lencesova, Lucia Csaderova, Tibor Stracina, Sona Hudecova, Petr Babula, Eva Rozborilova, Marie Novakova, Olga Krizanov. Haloperidol Affects Plasticity of Differentiated NG-108 Cells Through σ1R/IP Cellular and molecular neurobiology. vol 38. issue 1. 2018-08-13. PMID:28786032. |
haloperidol affects plasticity of differentiated ng-108 cells through σ1r/ip haloperidol is an antipsychotic agent that primarily acts as an antagonist of d2 dopamine receptors. |
2018-08-13 |
2023-08-13 |
Not clear |
| Catherine Lévesque, Giovanni Hernandez, Souha Mahmoudi, Frédéric Calon, Fabrizio Gasparini, Baltazar Gomez-Mancilla, Pierre J Blanchet, Daniel Lévesqu. Deficient striatal adaptation in aminergic and glutamatergic neurotransmission is associated with tardive dyskinesia in non-human primates exposed to antipsychotic drugs. Neuroscience. vol 361. 2018-06-14. PMID:28790021. |
using autoradiography, western blot and in situ hybridization techniques, we compared neurochemical components of the dopamine, serotonin, and glutamate neurotransmitter systems modulating striatal activity in monkeys chronically exposed to haloperidol and clozapine. |
2018-06-14 |
2023-08-13 |
human |
| Alice Servonnet, Ellie-Anna Minogianis, Claude Bouchard, Anne-Marie Bédard, Daniel Lévesque, Pierre-Paul Rompré, Anne-Noël Samah. Neurotensin in the nucleus accumbens reverses dopamine supersensitivity evoked by antipsychotic treatment. Neuropharmacology. vol 123. 2018-05-09. PMID:28522313. |
long-term exposure to antipsychotics like haloperidol can increase sensitivity to dopamine agonist stimulation. |
2018-05-09 |
2023-08-13 |
rat |
| Olivia Engmann, Albert Giralt, Jean-Antoine Giraul. Acute drug-induced spine changes in the nucleus accumbens are dependent on β-adducin. Neuropharmacology. vol 110. issue Pt A. 2018-02-22. PMID:27480796. |
here, we show that spine density and length are increased in the nucleus accumbens 24 h after a single injection of caffeine or quinpirole, a dopamine d2/d3 dopamine receptors agonist, whereas the dopamine antagonist haloperidol has opposite effects. |
2018-02-22 |
2023-08-13 |
mouse |
| R A N Pértile, M E Corvino, R C N Marchette, E Pavesi, J Cavalli, A Ramos, G S Izídi. The Quinpirole Hypolocomotive Effects are Strain and Route of Administration Dependent in SHR and SLA16 Isogenic Rats. Behavior genetics. vol 47. issue 5. 2018-02-05. PMID:28822047. |
haloperidol vhip did not elicit behavioural changes and no differences in the levels of d2 receptors and of dopamine transporter in the hippocampus were found. |
2018-02-05 |
2023-08-13 |
rat |
| Kazunori Suzuki, Akina Harada, Hirobumi Suzuki, Maki Miyamoto, Haruhide Kimur. TAK-063, a PDE10A Inhibitor with Balanced Activation of Direct and Indirect Pathways, Provides Potent Antipsychotic-Like Effects in Multiple Paradigms. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 9. 2018-01-09. PMID:26849714. |
however, excess activation of the direct pathway by a dopamine d1 receptor agonist skf82958 canceled antipsychotic-like effects of a dopamine d2 receptor antagonist haloperidol in methamphetamine (meth)-induced hyperactivity in rats. |
2018-01-09 |
2023-08-13 |
rat |
| Joanna Golebiowska, Rafal Rygul. Effects of acute dopaminergic and serotonergic manipulations in the ACI paradigm depend on the basal valence of cognitive judgement bias in rats. Behavioural brain research. vol 327. 2017-12-19. PMID:28212943. |
to test whether dopamine might play a similar role in non-human animals, in the present study, we evaluated the effects of acute injections of l-dopa, the d2 receptor antagonist haloperidol, and the ssri escitalopram on cognitive judgement bias of rats in the ambiguous-cue interpretation (aci) paradigm. |
2017-12-19 |
2023-08-13 |
rat |
| Samantha E Yohn, Daniela Alberati, Merce Correa, John D Salamon. Assessment of a glycine uptake inhibitor in animal models of effort-related choice behavior: implications for motivational dysfunctions. Psychopharmacology. vol 234. issue 9-10. 2017-12-13. PMID:28083675. |
interference with dopamine (da) transmission by administration of the da d2 family antagonist haloperidol biases behavior towards the lower effort option that can be obtained with minimal work, and previous research has shown that da interacts with other transmitters, including adenosine and gaba, to regulate effort-based choice. |
2017-12-13 |
2023-08-13 |
Not clear |
| Regina V Guarnieri, Luciano G Buratto, Carlos F A Gomes, Rafaela L Ribeiro, Altay A Lino de Souza, Lilian M Stein, José C Galduróz, Orlando F A Buen. Haloperidol increases false recognition memory of thematically related pictures in healthy volunteers. Human psychopharmacology. vol 32. issue 1. 2017-11-29. PMID:27925283. |
in a randomized, double-blind, placebo-controlled experiment, 24 young healthy volunteers ingested a 4-mg oral dose of haloperidol, a dopamine d |
2017-11-29 |
2023-08-13 |
human |
| L Lencesova, I Szadvari, P Babula, J Kubickova, B Chovancova, K Lopusna, I Rezuchova, Z Novakova, O Krizanova, M Novakov. Disruption of dopamine D1/D2 receptor complex is involved in the function of haloperidol in cardiac H9c2 cells. Life sciences. vol 191. 2017-11-28. PMID:29054453. |
disruption of dopamine d1/d2 receptor complex is involved in the function of haloperidol in cardiac h9c2 cells. |
2017-11-28 |
2023-08-13 |
Not clear |
| L Lencesova, I Szadvari, P Babula, J Kubickova, B Chovancova, K Lopusna, I Rezuchova, Z Novakova, O Krizanova, M Novakov. Disruption of dopamine D1/D2 receptor complex is involved in the function of haloperidol in cardiac H9c2 cells. Life sciences. vol 191. 2017-11-28. PMID:29054453. |
haloperidol is an antipsychotic agent and acts as dopamine d2 receptor (d2r) antagonist, as a prototypical ligand of sigma1 receptors (sig1r) and it increases expression of type 1 ip |
2017-11-28 |
2023-08-13 |
Not clear |
| Eliyahu Dremencov, Lubica Lacinova, Gunnar Flik, Joost Ha Folgering, Thomas Ifh Cremers, Ben Hc Westerin. Purinergic regulation of brain catecholamine neurotransmission: In vivo electrophysiology and microdialysis study in rats. General physiology and biophysics. vol 36. issue 4. 2017-11-24. PMID:28857746. |
the ability of antagonists of a2a receptors to potentiate the effect of haloperidol on brain norepinephrine and dopamine levels may enhance its clinical efficacy as an antipsychotic drug. |
2017-11-24 |
2023-08-13 |
rat |
| Arthur S C França, Larissa Muratori, George Carlos Nascimento, Catia Mendes Pereira, Sidarta Ribeiro, Bruno Lobão-Soare. Object recognition impairment and rescue by a dopamine D2 antagonist in hyperdopaminergic mice. Behavioural brain research. vol 308. 2017-11-21. PMID:27059337. |
we used a classical dopamine d2 antagonist, haloperidol, to modulate the levels of dopaminergic transmission in a dose-dependent manner, before or after exploring novel objects. |
2017-11-21 |
2023-08-13 |
mouse |
| Tobias Schwalbe, Jonas Kaindl, Harald Hübner, Peter Gmeine. Potent haloperidol derivatives covalently binding to the dopamine D2 receptor. Bioorganic & medicinal chemistry. vol 25. issue 19. 2017-10-16. PMID:28666858. |
potent haloperidol derivatives covalently binding to the dopamine d2 receptor. |
2017-10-16 |
2023-08-13 |
Not clear |
| Vijayapandi Pandy, Megala Narasingam, Kamini Vijeepallam, Syam Mohan, Vasudevan Mani, Zahurin Mohame. The ethyl acetate fraction of a methanolic extract of unripe noni (Morinda citrifolia Linn.) fruit exhibits a biphasic effect on the dopaminergic system in mice. Experimental animals. vol 66. issue 3. 2017-09-28. PMID:28450692. |
), which was evident from alleviation of haloperidol (a dopamine d |
2017-09-28 |
2023-08-13 |
mouse |
| Yan Ke, Wentao Li, Zhiqun Tan, Zhikuan Yan. Induction of dopamine D1 and D5 receptors in R28 cells by light exposures. Biochemical and biophysical research communications. vol 486. issue 3. 2017-06-02. PMID:28336436. |
notably, treatments of r28 cells with nanomolar dosages of dopamine (0-500 nm) directly downregulated expression of both drd1 and drd5, whereas haloperidol (0-50 nm), a drd2 antagonist, significantly induced expression of drd1. |
2017-06-02 |
2023-08-13 |
rat |
| Yasuharu Shinoda, Hideaki Tagashira, Md Shenuarin Bhuiyan, Hideyuki Hasegawa, Hiroshi Kanai, Kohji Fukunag. Haloperidol aggravates transverse aortic constriction-induced heart failure via mitochondrial dysfunction. Journal of pharmacological sciences. vol 131. issue 3. 2017-04-17. PMID:27435383. |
haloperidol is an antipsychotic drug that inhibits the dopamine d2 receptor among others. |
2017-04-17 |
2023-08-13 |
mouse |