Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Shobhit Kumar, Satish Kumar Gupta, Rakesh Pahw. Designing lisuride intranasal nanocarrier system for reduction of oxidative damage with enhanced dopamine level in brain for Parkinsonism. Journal of psychiatric research. vol 165. 2023-07-30. PMID:37517241. |
when lisuride ne was administered intranasally resulted in considerably higher dopamine concentrations (17.48 ± 0.05 ng/ml) in comparison to rats receiving haloperidol (7.28 ± 0.02 ng/ml). |
2023-07-30 |
2023-08-14 |
rat |
Sanja Strbe, Ivan Maria Smoday, Ivan Krezic, Luka Kalogjera, Vlasta Vukovic, Helena Zizek, Slaven Gojkovic, Hrvoje Vranes, Ivan Barisic, Suncana Sikiric, Marijan Tepes, Katarina Oroz, Filip Brkic, Martin Drinkovic, Lidija Beketic Oreskovic, Jelena Popic, Alenka Boban Blagaic, Anita Skrtic, Mario Staresinic, Sven Seiwerth, Predrag Sikiri. Innate Vascular Failure by Application of Neuroleptics, Amphetamine, and Domperidone Rapidly Induced Severe Occlusion/Occlusion-like Syndromes in Rats and Stable Gastric Pentadecapeptide BPC 157 as Therapy. Pharmaceuticals (Basel, Switzerland). vol 16. issue 6. 2023-06-28. PMID:37375736. |
in rats with complete calvariectomy, medication (bpc 157 10 µg/kg, 10 ng/kg ip or ig) was given 5 min after distinctive dopamine agents (mg/kg ip) (haloperidol (5), fluphenazine (5), clozapine (10), risperidone (5), olanzapine (10), quetiapine (10), or aripiprazole (10), domperidone (25), amphetamine (10), and combined amphetamine and haloperidol) and assessed at 15 min thereafter. |
2023-06-28 |
2023-08-14 |
rat |
Luis Felipe Sarmiento, Jorge Alexander Ríos-Flórez, Hector Andres Paez-Ardila, Pêssi Socorro Lima de Sousa, Antonio Olivera-La Rosa, Anderson Manoel Herculano Oliveira da Silva, Amauri Gouvei. Pharmacological Modulation of Temporal Discounting: A Systematic Review. Healthcare (Basel, Switzerland). vol 11. issue 7. 2023-04-13. PMID:37046974. |
the most important findings were the involvement of dopamine modulation in a u-shape for choosing the delayed outcome (metoclopradime, haloperidol, and amisulpride). |
2023-04-13 |
2023-08-14 |
Not clear |
Maciej M Jankowski, Bogna M Ignatowska-Jankowska, Wojciech Glac, Marek Wiergowski, Paulina Kazmierska-Grebowska, Artur H Swiergie. Intravenous haloperidol and cocaine alter the distribution of T CD3 Clinical and experimental pharmacology & physiology. 2023-02-21. PMID:36802086. |
intravenous haloperidol and cocaine alter the distribution of t cd3 the modulation of dopamine transmission evokes strong behavioral effects that can be achieved by commonly used psychoactive drugs such as haloperidol or cocaine. |
2023-02-21 |
2023-08-14 |
rat |
Maciej M Jankowski, Bogna M Ignatowska-Jankowska, Wojciech Glac, Marek Wiergowski, Paulina Kazmierska-Grebowska, Artur H Swiergie. Intravenous haloperidol and cocaine alter the distribution of T CD3 Clinical and experimental pharmacology & physiology. 2023-02-21. PMID:36802086. |
cocaine non-specifically increases dopamine transmission by blocking dopamine active transporter (dat) and evokes behavioral arousal, while haloperidol is a non-specific d2-like dopamine receptor antagonist with sedative effects. |
2023-02-21 |
2023-08-14 |
rat |
Hamna Rafiq, Muhammad Farhan, Hira Rafi, Sadia Rehman, Maria Arshad, Sarah Shakee. Inhibition of drug induced Parkinsonism by chronic supplementation of quercetin in haloperidol-treated wistars. Pakistan journal of pharmaceutical sciences. vol 35. issue 6. 2023-02-15. PMID:36789825. |
haloperidol causes drug-induced parkinsonism (dip) by blocking central dopamine receptors and causing extrapyramidal symptoms during long-term treatment. |
2023-02-15 |
2023-08-14 |
rat |
Jingheng Zhou, Jicheng Li, Amy B Papaneri, Guohong Cu. AJ76 and UH232 as potential agents for diagnosing early-stage Parkinson's disease. Neuropharmacology. 2023-01-09. PMID:36623805. |
the use of haloperidol in the original dnc test to challenge dopamine neurons was less than ideal, as it may cause extrapyramidal motor symptoms. |
2023-01-09 |
2023-08-14 |
mouse |
Jingheng Zhou, Jicheng Li, Amy B Papaneri, Guohong Cu. AJ76 and UH232 as potential agents for diagnosing early-stage Parkinson's disease. Neuropharmacology. 2023-01-09. PMID:36623805. |
here we report an improved dnc test, in which the original challenging agents, haloperidol and methylphenidate, are replaced by a single challenging agent, a dopamine autoreceptor preferring antagonist aj76 or uh232. |
2023-01-09 |
2023-08-14 |
mouse |
Kota Yamada, Koji Tod. Pupillary dynamics of mice performing a Pavlovian delay conditioning task reflect reward-predictive signals. Frontiers in systems neuroscience. vol 16. 2022-12-26. PMID:36567756. |
furthermore, we clarified that pupil size is still modulated by reward prediction even after the disruption of body movements by intraperitoneal injection of haloperidol, a dopamine d2 receptor antagonist. |
2022-12-26 |
2023-08-14 |
mouse |
Nicolette A Moya, Seongsik Yun, Stefan W Fleps, Madison M Martin, Jacob A Nadel, Lisa R Beutler, Larry S Zweifel, Jones G Parke. The effect of selective nigrostriatal dopamine excess on behaviors linked to the cognitive and negative symptoms of schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-11-15. PMID:36380221. |
we combined this manipulation with antipsychotic treatment (haloperidol) and compared it to brain-wide dopamine release via amphetamine treatment. |
2022-11-15 |
2023-08-14 |
mouse |
Stephanie T Hirschbichler, John C Rothwell, Sanjay G Manoha. Dopamine increases risky choice while D2 blockade shortens decision time. Experimental brain research. 2022-11-09. PMID:36350356. |
we here collected data on a standard gambling task in healthy volunteers given either placebo, 2.5 mg of the dopamine antagonist haloperidol or 100/25 mg of the dopamine precursor levodopa in a within-subject design. |
2022-11-09 |
2023-08-14 |
human |
Stephanie T Hirschbichler, John C Rothwell, Sanjay G Manoha. Dopamine increases risky choice while D2 blockade shortens decision time. Experimental brain research. 2022-11-09. PMID:36350356. |
shortened deliberation times on haloperidol occurred in low sensation-seekers only, suggesting a correlation between sensation-seeking personality trait and baseline dopamine levels. |
2022-11-09 |
2023-08-14 |
human |
Stephanie T Hirschbichler, John C Rothwell, Sanjay G Manoha. Dopamine increases risky choice while D2 blockade shortens decision time. Experimental brain research. 2022-11-09. PMID:36350356. |
we hypothesise that levodopa increases risk-taking behaviour via overstimulation at both d1 and d2 receptor level, while a single low dose of haloperidol, as previously reported (frank and o'reilly 2006), may block d2 receptors pre- and post-synaptically and may paradoxically lead to higher striatal dopamine acting on remaining striatal d1 receptors, causing speedier decision without influencing risk tolerance. |
2022-11-09 |
2023-08-14 |
human |
Roberto De Masi, Stefania Orlando, Maria Carmela Cost. Dementia-Associated Compulsive Singing (DACS): Presentation of Unpublished Clinical Cases Miniseries. International journal of environmental research and public health. vol 19. issue 17. 2022-09-09. PMID:36078557. |
previously described only as a "punding" aspect of the dopamine dysregulation syndrome (dds) in the parkinson's disease (pd), compulsive singing has now been described, for the first time, in four non-pd patients effectively treated with haloperidol or quetiapine. |
2022-09-09 |
2023-08-14 |
Not clear |
Nina Zech, Barbara Sinne. [Anaesthesia and Perioperative Management for Patients with Parkinson's Disease]. Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS. vol 57. issue 9. 2022-09-01. PMID:36049741. |
besides, all dopamine antagonists sometimes used for prophylaxis or therapy of delirium or ponv (haloperidol, metoclopramide) are contraindicated. |
2022-09-01 |
2023-08-14 |
Not clear |
Yoko Hirata, Kohei Oka, Shotaro Yamamoto, Hiroki Watanabe, Kentaro Oh-Hashi, Tasuku Hirayama, Hideko Nagasawa, Hiroshi Takemori, Kyoji Furut. Haloperidol Prevents Oxytosis/Ferroptosis by Targeting Lysosomal Ferrous Ions in a Manner Independent of Dopamine D2 and Sigma-1 Receptors. ACS chemical neuroscience. 2022-09-01. PMID:36050287. |
haloperidol prevents oxytosis/ferroptosis by targeting lysosomal ferrous ions in a manner independent of dopamine d2 and sigma-1 receptors. |
2022-09-01 |
2023-08-14 |
mouse |
Yoko Hirata, Kohei Oka, Shotaro Yamamoto, Hiroki Watanabe, Kentaro Oh-Hashi, Tasuku Hirayama, Hideko Nagasawa, Hiroshi Takemori, Kyoji Furut. Haloperidol Prevents Oxytosis/Ferroptosis by Targeting Lysosomal Ferrous Ions in a Manner Independent of Dopamine D2 and Sigma-1 Receptors. ACS chemical neuroscience. 2022-09-01. PMID:36050287. |
haloperidol is a widely used antipsychotic agent that exerts antipsychotic effects through a strong antagonism of dopamine d2 receptors. |
2022-09-01 |
2023-08-14 |
mouse |
Katarína Pichová, Ľubica Kubíková, Ľubor Košťá. The Acute Pharmacological Manipulation of Dopamine Receptors Modulates Judgment Bias in Japanese Quail. Frontiers in physiology. vol 13. 2022-05-31. PMID:35634149. |
in experiment 1, each bird received five treatments (0.1 and 1.0 mg/kg of dopamine d1 receptor antagonist sch 23390, 0.05 and 0.5 mg/kg of dopamine d2 receptor antagonist haloperidol, and saline control) in a different order, according to a latin square design. |
2022-05-31 |
2023-08-13 |
Not clear |
Murat Gursoy, Zulfiye Gul, R Levent Buyukuysa. Sigma receptor ligands haloperidol and ifenprodil attenuate hypoxia induced dopamine release in rat striatum. Neurological research. 2022-05-02. PMID:35499231. |
sigma receptor ligands haloperidol and ifenprodil attenuate hypoxia induced dopamine release in rat striatum. |
2022-05-02 |
2023-08-13 |
rat |
Murat Gursoy, Zulfiye Gul, R Levent Buyukuysa. Sigma receptor ligands haloperidol and ifenprodil attenuate hypoxia induced dopamine release in rat striatum. Neurological research. 2022-05-02. PMID:35499231. |
we aimed to investigate the hypothesis that sigma receptor ligands, haloperidol and ifenprodil, attenuate hypoxia-induced striatal dopamine release in vitro and determine the possible mechanisms. |
2022-05-02 |
2023-08-13 |
rat |