| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alessandra Bonito-Oliva, Simone Pallottino, Jesus Bertran-Gonzalez, Jean-Antoine Girault, Emmanuel Valjent, Gilberto Fison. Haloperidol promotes mTORC1-dependent phosphorylation of ribosomal protein S6 via dopamine- and cAMP-regulated phosphoprotein of 32 kDa and inhibition of protein phosphatase-1. Neuropharmacology. vol 72. 2014-02-11. PMID:23643747. |
we found that administration of haloperidol increased ser240/244 phosphorylation in a subpopulation of gaba-ergic medium spiny neurons (msns), which preferentially express dopamine d2 receptors (d2rs). |
2014-02-11 |
2023-08-12 |
Not clear |
| Esther Leal, Begoña Fernández-Durán, Maria Josep Agulleiro, Marta Conde-Siera, Jesús Manuel Míguez, José Miguel Cerdá-Reverte. Effects of dopaminergic system activation on feeding behavior and growth performance of the sea bass (Dicentrarchus labrax): a self-feeding approach. Hormones and behavior. vol 64. issue 1. 2014-02-04. PMID:23747830. |
unexpectedly, dietary administration of haloperidol, a d2-receptor antagonist, cannot block dopamine effects but also induces a decline of the food intake. |
2014-02-04 |
2023-08-12 |
mouse |
| C H Rӧder, S Dieleman, F M van der Veen, D Linde. Systematic review of the influence of antipsychotics on the blood oxygenation level-dependent signal of functional magnetic resonance imaging. Current medicinal chemistry. vol 20. issue 3. 2014-01-17. PMID:23157637. |
however, based on the results for different antipsychotics (haloperidol, olanzapine, quetiapine and risperidone) we found evidence that the affinity to the dopamine (da) d(2)-receptor may influence bold-signal. |
2014-01-17 |
2023-08-12 |
Not clear |
| Chen Yang, Shun-Nan Ge, Jia-Rui Zhang, Lei Chen, Zhi-Qiang Yan, Li-Jun Heng, Tian-Zhi Zhao, Wei-Xin Li, Dong Jia, Jun-Ling Zhu, Guo-Dong Ga. Systemic blockade of dopamine D2-like receptors increases high-voltage spindles in the globus pallidus and motor cortex of freely moving rats. PloS one. vol 8. issue 6. 2014-01-14. PMID:23755132. |
the results showed that the dopamine d₂-like receptor antagonists, raclopride and haloperidol, significantly increased the number and duration of hvss, and the relative power associated with hvs activity in the gp and m1 cortex. |
2014-01-14 |
2023-08-12 |
rat |
| David M Cole, Christian F Beckmann, Nicole Y L Oei, Stephanie Both, Joop M A van Gerven, Serge A R B Rombout. Differential and distributed effects of dopamine neuromodulations on resting-state network connectivity. NeuroImage. vol 78. 2014-01-06. PMID:23603346. |
we compared rsn connectivity in 3 groups of healthy volunteers given dopamine antagonist (haloperidol; n=18) or agonistic (levodopa; n=16) drugs, or a placebo (n=15). |
2014-01-06 |
2023-08-12 |
human |
| Dorin Yael, Dagmar H Zeef, Daniel Sand, Anan Moran, Donald B Katz, Dana Cohen, Yasin Temel, Izhar Bar-Ga. Haloperidol-induced changes in neuronal activity in the striatum of the freely moving rat. Frontiers in systems neuroscience. vol 7. 2013-12-31. PMID:24379762. |
haloperidol, a dopamine d2 antagonist, is commonly used in multiple psychiatric conditions and motor abnormalities. |
2013-12-31 |
2023-08-12 |
rat |
| Ileana Marinescu, I Udriştoiu, D Marinesc. Choroid plexus calcification: clinical, neuroimaging and histopathological correlations in schizophrenia. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 54. issue 2. 2013-12-27. PMID:23771083. |
antipsychotics with high capacity to block d2 dopamine receptors (haloperidol model) can aggravate apoptotic mechanisms of the brain areas involved in cognition and disrupts the functional integrity of the bbb due to decreased of choroid plexus blood flow because of the narrowing of cerebral small vessels. |
2013-12-27 |
2023-08-12 |
Not clear |
| M Mizuno, H Sotoyama, H Namba, M Shibuya, T Eda, R Wang, T Okubo, K Nagata, Y Iwakura, H Naw. ErbB inhibitors ameliorate behavioral impairments of an animal model for schizophrenia: implication of their dopamine-modulatory actions. Translational psychiatry. vol 3. 2013-12-23. PMID:23632456. |
zd1839 infusion also decreased the busting activity of nigral dopamine (da) neurons and reduced pallidal da metabolism, a result that mimics the anti-dopaminergic profile of risperidone and haloperidol in this brain region. |
2013-12-23 |
2023-08-12 |
rat |
| Judith P Golden, Joseph A Demaro, Amanda Knoten, Masato Hoshi, Elizabeth Pehek, Eugene M Johnson, Robert W Gereau, Sanjay Jai. Dopamine-dependent compensation maintains motor behavior in mice with developmental ablation of dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 43. 2013-12-23. PMID:24155314. |
treatment of aged mutant mice with the dopamine receptor antagonist haloperidol precipitated motor behavior deficits in aged mutant mice, indicating that <5% of striatal dopamine is sufficient to maintain motor function in these mice. |
2013-12-23 |
2023-08-12 |
mouse |
| W J Schmidt, B Zadow, B D Kretschmer, W Haube. Anticataleptic potencies of glutamate-antagonists. Amino acids. vol 1. issue 2. 2013-11-06. PMID:24194107. |
the results show that the non-competitive nmda antagonists dizocilpine and memantine as well as the competitive antagonists cgp 39551, cgp 37849 and cppene antagonized dopamine d2 receptor mediated catalepsy induced by haloperidol. |
2013-11-06 |
2023-08-12 |
Not clear |
| Anne-Marie Bédard, Jérôme Maheux, Daniel Lévesque, Anne-Noël Samah. Prior haloperidol, but not olanzapine, exposure augments the pursuit of reward cues: implications for substance abuse in schizophrenia. Schizophrenia bulletin. vol 39. issue 3. 2013-10-28. PMID:22927669. |
we have shown previously that rats withdrawn from continuous haloperidol (hal) treatment (via subcutaneous minipump) develop dopamine supersensitivity and pursue reward cues more vigorously than hal-naive rats following an amphetamine (amph) challenge. |
2013-10-28 |
2023-08-12 |
rat |
| Sanders A McDougall, Alena Mohd-Yusof, Graham J Kaplan, Zuhair I Abdulla, Ryan J Lee, Cynthia A Crawfor. Postnatal manganese exposure does not alter dopamine autoreceptor sensitivity in adult and adolescent male rats. European journal of pharmacology. vol 706. issue 1-3. 2013-10-28. PMID:23458069. |
to this end, male rats were exposed to mn on pd 1-21 and autoreceptor functioning was tested 7 or 70 days later by measuring (a) dopamine synthesis (i.e., dopa accumulation) in the dorsal striatum after quinpirole or haloperidol treatment and (b) behavioral responsiveness after low-dose apomorphine treatment. |
2013-10-28 |
2023-08-12 |
rat |
| Sanders A McDougall, Alena Mohd-Yusof, Graham J Kaplan, Zuhair I Abdulla, Ryan J Lee, Cynthia A Crawfor. Postnatal manganese exposure does not alter dopamine autoreceptor sensitivity in adult and adolescent male rats. European journal of pharmacology. vol 706. issue 1-3. 2013-10-28. PMID:23458069. |
the dopamine synthesis experiment also produced classic autoreceptor effects, because quinpirole decreased dorsal striatal dopa accumulation; whereas, haloperidol increased dopa levels in control rats, but not in rats given the nerve impulse inhibitor γ-butyrolactone. |
2013-10-28 |
2023-08-12 |
rat |
| Auxiliadora Mena, Luis G De la Cas. Prepulse inhibition modulation by contextual conditioning of dopaminergic activity. Behavioural brain research. vol 252. 2013-10-28. PMID:23756135. |
to test this hypothesis, we conducted two experiments that revealed that contextual cues acquired the property to modulate pre-pulse inhibition by prior pairings of such context with the dopamine antagonist haloperidol (experiment 1), and with the dopamine agonist d-amphetamine (experiment 2). |
2013-10-28 |
2023-08-12 |
Not clear |
| Fabrizio Sanna, Maria Rosaria Melis, Laura Angioni, Antonio Argiola. Clavulanic acid induces penile erection and yawning in male rats: comparison with apomorphine. Pharmacology, biochemistry, and behavior. vol 103. issue 4. 2013-10-24. PMID:23234836. |
clavulanic acid responses were reduced by about 55% by haloperidol, a dopamine d2 receptor antagonist (0.1mg/kg ip), and by d(ch(2))(5)tyr(me)(2)-orn(8)-vasotocin, an oxytocin receptor antagonist (2 μg/rat icv), both given 15 min before clavulanic acid. |
2013-10-24 |
2023-08-12 |
rat |
| Roseline I Porchet, Linde Boekhoudt, Bettina Studer, Praveen K Gandamaneni, Nisha Rani, Somashekar Binnamangala, Ulrich Müller, Luke Clar. Opioidergic and dopaminergic manipulation of gambling tendencies: a preliminary study in male recreational gamblers. Frontiers in behavioral neuroscience. vol 7. 2013-10-10. PMID:24109443. |
the objective of the current study was to assess the effects of the opioid receptor antagonist naltrexone and the dopamine d2 receptor antagonist haloperidol on gambling behavior. |
2013-10-10 |
2023-08-12 |
human |
| James B Koprich, Philippe Huot, Susan H Fox, Keith Jarvie, Anthony E Lang, Philip Seeman, Jonathan M Brotchi. The effects of fast-off-D2 receptor antagonism on L-DOPA-induced dyskinesia and psychosis in parkinsonian macaques. Progress in neuro-psychopharmacology & biological psychiatry. vol 43. 2013-09-19. PMID:23306217. |
because of the marked reduction in brain dopamine in pd and the resultant dopamine d2 receptor supersensitivity, it is impossible to use standard potent dopamine d2 receptor antagonists such as haloperidol to alleviate side effects without compromising the anti-parkinsonian benefits of l-dopa. |
2013-09-19 |
2023-08-12 |
monkey |
| Pedro Porto Alegre Baptista, Priscylla Nunes de Senna, Mariana Fontoura Paim, Lisiani Saur, Martina Blank, Patricia do Nascimento, Jocemar Ilha, Mônica Ryff Moreira Vianna, Régis Gemerasca Mestriner, Matilde Achaval, Léder Leal Xavie. Physical exercise down-regulated locomotor side effects induced by haloperidol treatment in Wistar rats. Pharmacology, biochemistry, and behavior. vol 104. 2013-09-17. PMID:23290938. |
extra-pyramidal symptoms (eps) such as akinesia, dystonia, gait alteration and tremors are observed when dopamine d2-receptors are blocked by pharmacological agents such as haloperidol. |
2013-09-17 |
2023-08-12 |
rat |
| Deborah S Kreiss, Catherine F Coffman, Nicholas R Fiacco, Jason C Granger, Bernadette M Helton, Jennifer C Jackson, Leonid V Kim, Rishi S Mistry, Tammie M Mizer, Lolita V Palmer, Jay A Vacca, Stuart S Winkler, Benjamin A Zimme. Ritualistic chewing behavior induced by mCPP in the rat is an animal model of obsessive compulsive disorder. Pharmacology, biochemistry, and behavior. vol 104. 2013-09-17. PMID:23333679. |
the effects upon the rcbs induced by mcpp (1 mg/kg) were evaluated following treatments with either the serotonin antagonist mianserin (3 mg/kg), the dopamine antagonist haloperidol (1 mg/kg), the gaba modulator diazepam (10 mg/kg), or the serotonin uptake inhibitors clomipramine and fluvoxamine (15 mg/kg). |
2013-09-17 |
2023-08-12 |
rat |
| Pei Jiang, Wen-Yuan Zhang, Huan-De Li, Hua-Lin Cai, Ying Xu. Repeated haloperidol administration has no effect on vitamin D signaling but increase retinoid X receptors and Nur77 expression in rat prefrontal cortex. Cellular and molecular neurobiology. vol 33. issue 3. 2013-09-04. PMID:23324997. |
by blocking dopamine d2 receptor, haloperidol induces nur77 expression, suggesting a modulatory role of nur77 in brain dopamine system. |
2013-09-04 |
2023-08-12 |
rat |