| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Kozell, K Meshu. Alterations in nerve terminal glutamate immunoreactivity in the nucleus accumbens and ventral tegmental area following single and repeated doses of cocaine. Psychopharmacology. vol 165. issue 4. 2003-03-20. PMID:12459930. |
however, little is known about long-term changes in glutamate transmission following a single dose of cocaine. |
2003-03-20 |
2023-08-12 |
Not clear |
| B Kozell, K Meshu. Alterations in nerve terminal glutamate immunoreactivity in the nucleus accumbens and ventral tegmental area following single and repeated doses of cocaine. Psychopharmacology. vol 165. issue 4. 2003-03-20. PMID:12459930. |
our laboratory has previously reported that a single dose of cocaine, but not repeated cocaine, decreased the density of presynaptic nerve terminal glutamate immunolabeling in the nucleus accumbens when measured 3 days later. |
2003-03-20 |
2023-08-12 |
Not clear |
| B Kozell, K Meshu. Alterations in nerve terminal glutamate immunoreactivity in the nucleus accumbens and ventral tegmental area following single and repeated doses of cocaine. Psychopharmacology. vol 165. issue 4. 2003-03-20. PMID:12459930. |
this study extends the results of our previous work by examining nerve terminal glutamate immunoreactivity 17 days after the last dose of cocaine. |
2003-03-20 |
2023-08-12 |
Not clear |
| Glenda C Harris, Gary Aston-Jone. Critical role for ventral tegmental glutamate in preference for a cocaine-conditioned environment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 1. 2003-03-17. PMID:12496942. |
we sought to determine if glutamate receptor activation is also crucial to the development of a conditioned place preference (cpp) to cocaine's rewarding effects. |
2003-03-17 |
2023-08-12 |
rat |
| Glenda C Harris, Gary Aston-Jone. Critical role for ventral tegmental glutamate in preference for a cocaine-conditioned environment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 1. 2003-03-17. PMID:12496942. |
microinjections of the glutamate antagonists completely blocked the development of a cocaine cpp when given within, but not when given outside of, the vta. |
2003-03-17 |
2023-08-12 |
rat |
| Michael A Sutton, Eric F Schmidt, Kwang-Ho Choi, Christina A Schad, Kim Whisler, Diana Simmons, David A Karanian, Lisa M Monteggia, Rachael L Neve, David W Sel. Extinction-induced upregulation in AMPA receptors reduces cocaine-seeking behaviour. Nature. vol 421. issue 6918. 2003-01-30. PMID:12511956. |
here we show that extinction training during withdrawal from chronic cocaine self-administration induces experience-dependent increases in the glur1 and glur2/3 subunits of ampa (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate) glutamate receptors in the nucleus accumbens shell, a brain region that is critically involved in cocaine reward. |
2003-01-30 |
2023-08-12 |
Not clear |
| Jeffrey M Witkin, Maciej Gasior, Christina Schad, Agustin Zapata, Toni Shippenberg, Theresa Hartman, Barbara S Slushe. NAALADase (GCP II) inhibition prevents cocaine-kindled seizures. Neuropharmacology. vol 43. issue 3. 2002-12-17. PMID:12243764. |
the prediction that inhibition of naaladase, an enzyme catalyzing the cleavage of glutamate from n-acetyl-aspartyl-glutamate, would produce antiepileptogenic effects against cocaine was tested. |
2002-12-17 |
2023-08-12 |
mouse |
| Zheng-Xiong Xi, Sammanda Ramamoorthy, David A Baker, Hui Shen, Devadoss J Samuvel, Peter W Kaliva. Modulation of group II metabotropic glutamate receptor signaling by chronic cocaine. The Journal of pharmacology and experimental therapeutics. vol 303. issue 2. 2002-11-22. PMID:12388642. |
modulation of group ii metabotropic glutamate receptor signaling by chronic cocaine. |
2002-11-22 |
2023-08-12 |
human |
| Zheng-Xiong Xi, Sammanda Ramamoorthy, David A Baker, Hui Shen, Devadoss J Samuvel, Peter W Kaliva. Modulation of group II metabotropic glutamate receptor signaling by chronic cocaine. The Journal of pharmacology and experimental therapeutics. vol 303. issue 2. 2002-11-22. PMID:12388642. |
repeated cocaine produces enduring neuroadaptations in glutamate transmission in the nucleus accumbens that are thought to contribute to addiction. |
2002-11-22 |
2023-08-12 |
human |
| Zheng-Xiong Xi, Sammanda Ramamoorthy, David A Baker, Hui Shen, Devadoss J Samuvel, Peter W Kaliva. Modulation of group II metabotropic glutamate receptor signaling by chronic cocaine. The Journal of pharmacology and experimental therapeutics. vol 303. issue 2. 2002-11-22. PMID:12388642. |
group ii metabotropic glutamate autoreceptors (mglur2/3) regulate glutamate release, and this study investigates whether repeated cocaine injection produces long-lasting alterations in mglur2/3 content, phosphorylation, and physiology. |
2002-11-22 |
2023-08-12 |
human |
| S Scheggi, S Mangiavacchi, F Masi, C Gambarana, A Tagliamonte, M G De Monti. Dizocilpine infusion has a different effect in the development of morphine and cocaine sensitization: behavioral and neurochemical aspects. Neuroscience. vol 109. issue 2. 2002-04-12. PMID:11801363. |
we conclude that: (i) morphine sensitization is a neuroadaptive phenomenon which does not appear to require nmda receptor activity in order to develop; (ii) cocaine sensitization is clearly dependent on nmda receptor activity, as dizocilpine infusion prevented the occurrence of glutamate receptors modifications as well as the development of sensitization. |
2002-04-12 |
2023-08-12 |
rat |
| J L Cornish, P W Kaliva. Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 15. 2002-04-08. PMID:10899176. |
glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction. |
2002-04-08 |
2023-08-12 |
Not clear |
| J L Cornish, P W Kaliva. Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 15. 2002-04-08. PMID:10899176. |
however, repeated exposure to cocaine is associated with the recruitment of glutamate transmission. |
2002-04-08 |
2023-08-12 |
Not clear |
| J L Cornish, P W Kaliva. Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 15. 2002-04-08. PMID:10899176. |
reinstatement was produced by a systemic injection of cocaine or by the microinjection of the glutamate receptor agonist ampa or dopamine into the nucleus accumbens. |
2002-04-08 |
2023-08-12 |
Not clear |
| W-K Park, A A Bari, A R Jey, S M Anderson, R D Spealman, J K Rowlett, R C Pierc. Cocaine administered into the medial prefrontal cortex reinstates cocaine-seeking behavior by increasing AMPA receptor-mediated glutamate transmission in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 7. 2002-04-08. PMID:11923456. |
cocaine administered into the medial prefrontal cortex reinstates cocaine-seeking behavior by increasing ampa receptor-mediated glutamate transmission in the nucleus accumbens. |
2002-04-08 |
2023-08-12 |
human |
| G Hotsenpiller, M Giorgetti, M E Wol. Alterations in behaviour and glutamate transmission following presentation of stimuli previously associated with cocaine exposure. The European journal of neuroscience. vol 14. issue 11. 2002-04-05. PMID:11860480. |
alterations in behaviour and glutamate transmission following presentation of stimuli previously associated with cocaine exposure. |
2002-04-05 |
2023-08-12 |
human |
| G Hotsenpiller, M Giorgetti, M E Wol. Alterations in behaviour and glutamate transmission following presentation of stimuli previously associated with cocaine exposure. The European journal of neuroscience. vol 14. issue 11. 2002-04-05. PMID:11860480. |
to study the role of glutamate in cocaine-conditioned responses, we developed a rat model in which conditioned locomotion is produced by repeated pairing of cocaine with discrete stimuli (flashing light and metronome). |
2002-04-05 |
2023-08-12 |
human |
| J L Cornish, P W Kaliva. Cocaine sensitization and craving: differing roles for dopamine and glutamate in the nucleus accumbens. Journal of addictive diseases. vol 20. issue 3. 2002-02-01. PMID:11681592. |
cocaine sensitization and craving: differing roles for dopamine and glutamate in the nucleus accumbens. |
2002-02-01 |
2023-08-12 |
Not clear |
| J L Cornish, P W Kaliva. Cocaine sensitization and craving: differing roles for dopamine and glutamate in the nucleus accumbens. Journal of addictive diseases. vol 20. issue 3. 2002-02-01. PMID:11681592. |
this review describes the effect of chronic cocaine administration on dopamine and glutamate transmission in the nucleus accumbens, and discusses the relevance of these changes in the initiation of drug craving and relapse to drug abuse. |
2002-02-01 |
2023-08-12 |
Not clear |
| L B Kozell, C K Meshu. The effects of acute or repeated cocaine administration on nerve terminal glutamate within the rat mesolimbic system. Neuroscience. vol 106. issue 1. 2001-12-04. PMID:11564413. |
the effects of acute or repeated cocaine administration on nerve terminal glutamate within the rat mesolimbic system. |
2001-12-04 |
2023-08-12 |
rat |