| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Churchill, C J Swanson, M Urbina, P W Kaliva. Repeated cocaine alters glutamate receptor subunit levels in the nucleus accumbens and ventral tegmental area of rats that develop behavioral sensitization. Journal of neurochemistry. vol 72. issue 6. 1999-06-14. PMID:10349849. |
repeated cocaine alters glutamate receptor subunit levels in the nucleus accumbens and ventral tegmental area of rats that develop behavioral sensitization. |
1999-06-14 |
2023-08-12 |
human |
| L Churchill, C J Swanson, M Urbina, P W Kaliva. Repeated cocaine alters glutamate receptor subunit levels in the nucleus accumbens and ventral tegmental area of rats that develop behavioral sensitization. Journal of neurochemistry. vol 72. issue 6. 1999-06-14. PMID:10349849. |
increased glutamate transmission in the nucleus accumbens and ventral tegmental area has been proposed as a mechanism underlying sensitized behavioral responses to repeated cocaine administration. |
1999-06-14 |
2023-08-12 |
human |
| L Churchill, C J Swanson, M Urbina, P W Kaliva. Repeated cocaine alters glutamate receptor subunit levels in the nucleus accumbens and ventral tegmental area of rats that develop behavioral sensitization. Journal of neurochemistry. vol 72. issue 6. 1999-06-14. PMID:10349849. |
glur1, glur2/3, and nmdar1 subunits of glutamate receptors were quantified from immunoblots in these brain nuclei in rats at 24 h and 3 weeks after discontinuing 1 week of daily cocaine injections. |
1999-06-14 |
2023-08-12 |
human |
| L Churchill, C J Swanson, M Urbina, P W Kaliva. Repeated cocaine alters glutamate receptor subunit levels in the nucleus accumbens and ventral tegmental area of rats that develop behavioral sensitization. Journal of neurochemistry. vol 72. issue 6. 1999-06-14. PMID:10349849. |
the functional importance of the increases in glutamate receptor subunit levels is suggested by the fact that the changes were present only in rats that developed behavioral sensitization to repeated cocaine administration. |
1999-06-14 |
2023-08-12 |
human |
| D H Penning, F Dexter, J L Henderson, D H Chestnut, J D Reynold. Bolus maternal cocaine administration does not produce a large increase in fetal sheep cerebral cortical glutamate concentration. Neurotoxicology and teratology. vol 21. issue 2. 1999-06-09. PMID:10192278. |
bolus maternal cocaine administration does not produce a large increase in fetal sheep cerebral cortical glutamate concentration. |
1999-06-09 |
2023-08-12 |
human |
| D H Penning, F Dexter, J L Henderson, D H Chestnut, J D Reynold. Bolus maternal cocaine administration does not produce a large increase in fetal sheep cerebral cortical glutamate concentration. Neurotoxicology and teratology. vol 21. issue 2. 1999-06-09. PMID:10192278. |
we tested whether acute cocaine exposure produces large increases in glutamate release in the intact cerebral cortex of the near-term fetal sheep. |
1999-06-09 |
2023-08-12 |
human |
| D H Penning, F Dexter, J L Henderson, D H Chestnut, J D Reynold. Bolus maternal cocaine administration does not produce a large increase in fetal sheep cerebral cortical glutamate concentration. Neurotoxicology and teratology. vol 21. issue 2. 1999-06-09. PMID:10192278. |
we conclude that if cocaine increases glutamate concentration in the developing cerebral cortex, the increase in magnitude is small relative to the changes produced by other interventions such as ethanol or umbilical cord occlusion. |
1999-06-09 |
2023-08-12 |
human |
| D H Penning, F Dexter, J L Henderson, D H Chestnut, J D Reynold. Bolus maternal cocaine administration does not produce a large increase in fetal sheep cerebral cortical glutamate concentration. Neurotoxicology and teratology. vol 21. issue 2. 1999-06-09. PMID:10192278. |
mechanisms other than increases in cerebral cortical glutamate concentration probably contribute to the neurologic injury associated with prenatal cocaine exposure. |
1999-06-09 |
2023-08-12 |
human |
| A S Keys, G P Mark, N Emre, C K Meshu. Reduced glutamate immunolabeling in the nucleus accumbens following extended withdrawal from self-administered cocaine. Synapse (New York, N.Y.). vol 30. issue 4. 1999-01-22. PMID:9826231. |
reduced glutamate immunolabeling in the nucleus accumbens following extended withdrawal from self-administered cocaine. |
1999-01-22 |
2023-08-12 |
rat |
| A S Keys, G P Mark, N Emre, C K Meshu. Reduced glutamate immunolabeling in the nucleus accumbens following extended withdrawal from self-administered cocaine. Synapse (New York, N.Y.). vol 30. issue 4. 1999-01-22. PMID:9826231. |
alterations in the density of gaba and glutamate immunolabeling within nerve terminals in the shell region of the nucleus accumbens were assessed in rats withdrawn from intravenous cocaine exposure. |
1999-01-22 |
2023-08-12 |
rat |
| A S Keys, G P Mark, N Emre, C K Meshu. Reduced glutamate immunolabeling in the nucleus accumbens following extended withdrawal from self-administered cocaine. Synapse (New York, N.Y.). vol 30. issue 4. 1999-01-22. PMID:9826231. |
a significant 27.7% decrease in vesicular glutamate density within asymmetrical nerve terminals was observed in animals that self-administered cocaine as compared to controls. |
1999-01-22 |
2023-08-12 |
rat |
| A S Keys, G P Mark, N Emre, C K Meshu. Reduced glutamate immunolabeling in the nucleus accumbens following extended withdrawal from self-administered cocaine. Synapse (New York, N.Y.). vol 30. issue 4. 1999-01-22. PMID:9826231. |
this group also showed an 18.6% decrease in vesicular nerve terminal glutamate immunolabeling as compared to animals that were administered a similar total dose of cocaine in a response-independent fashion. |
1999-01-22 |
2023-08-12 |
rat |
| A S Keys, G P Mark, N Emre, C K Meshu. Reduced glutamate immunolabeling in the nucleus accumbens following extended withdrawal from self-administered cocaine. Synapse (New York, N.Y.). vol 30. issue 4. 1999-01-22. PMID:9826231. |
these results demonstrate that glutamate density is suppressed in the shell region of the nucleus accumbens following withdrawal from 2 weeks of cocaine exposure. |
1999-01-22 |
2023-08-12 |
rat |
| M B Ghasemzadeh, L C Nelson, X Y Lu, P W Kaliva. Neuroadaptations in ionotropic and metabotropic glutamate receptor mRNA produced by cocaine treatment. Journal of neurochemistry. vol 72. issue 1. 1999-01-21. PMID:9886066. |
neuroadaptations in ionotropic and metabotropic glutamate receptor mrna produced by cocaine treatment. |
1999-01-21 |
2023-08-12 |
Not clear |
| M B Ghasemzadeh, L C Nelson, X Y Lu, P W Kaliva. Neuroadaptations in ionotropic and metabotropic glutamate receptor mRNA produced by cocaine treatment. Journal of neurochemistry. vol 72. issue 1. 1999-01-21. PMID:9886066. |
the expression of glutamate receptor/subunit mrnas was examined 3 weeks after discontinuing 1 week of daily injections of saline or cocaine. |
1999-01-21 |
2023-08-12 |
Not clear |
| C K Meshul, K Noguchi, N Emre, G Elliso. Cocaine-induced changes in glutamate and GABA immunolabeling within rat habenula and nucleus accumbens. Synapse (New York, N.Y.). vol 30. issue 2. 1998-11-16. PMID:9723791. |
we found that cocaine treatment resulted in a significant decrease in the density of nerve-terminal gaba immunolabeling located within the lhb in animals taken off the drug for either 1 or 14 days, while there was no change in the density of glutamate immunolabeling. |
1998-11-16 |
2023-08-12 |
rat |
| C K Meshul, K Noguchi, N Emre, G Elliso. Cocaine-induced changes in glutamate and GABA immunolabeling within rat habenula and nucleus accumbens. Synapse (New York, N.Y.). vol 30. issue 2. 1998-11-16. PMID:9723791. |
in the nacs, there was a decrease in the density of glutamate immunolabeling within nerve terminals 1 day but not 14 days after cocaine administration. |
1998-11-16 |
2023-08-12 |
rat |
| O Manzoni, D Pujalte, J Williams, J Bockaer. Decreased presynaptic sensitivity to adenosine after cocaine withdrawal. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 19. 1998-10-09. PMID:9742166. |
here, we report that long-term (1 week) withdrawal from chronic cocaine reduced the potency of adenosine to presynaptically inhibit glutamate (glu) release by activating adenosine a1 receptors. |
1998-10-09 |
2023-08-12 |
Not clear |
| R W Rockhol. Glutamatergic involvement in psychomotor stimulant action. Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques. vol 50. 1998-08-06. PMID:9670779. |
the sympathomimetic psychomotor stimulants, including cocaine, amphetamines, and the phenylethylamine amphetamine-like derivatives, exert actions in mammalian systems that implicate involvement of the excitatory neurotransmitter, glutamate and its receptors. |
1998-08-06 |
2023-08-12 |
Not clear |
| T R Koste. Pharmacotherapy of cerebral ischemia in cocaine dependence. Drug and alcohol dependence. vol 49. issue 2. 1998-07-14. PMID:9543650. |
the review covers five areas: (1) cerebral ischemia and neuropsychological impairment in cocaine abusers, (2) neuroimaging evidence for cerebral perfusion defects in cocaine abusers, (3) mechanisms for cocaine induced cerebral thrombosis, (4) neurotoxicity from cerebral ischemia and excitatory amino acids, (5) glutamate antagonists as potential treatment agents for cocaine induced neurotoxicity. |
1998-07-14 |
2023-08-12 |
Not clear |