| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sierra M Webb, Bailey W Miller, Melissa G Wroten, Arianne Sacramento, Katherine O Travis, Tod E Kippin, Osnat Ben-Shahar, Karen K Szumlinsk. Replication and extension of the subregion selectivity of glutamate-related changes within the nucleus accumbens associated with the incubation of cocaine-craving. Pharmacology, biochemistry, and behavior. 2024-10-10. PMID:39389205. |
here, we employed a combination of in vivo microdialysis and immunoblotting approaches to further examine changes in biochemical indices of glutamate transmission within na subregions that accompany the incubation of cocaine-craving exhibited by male rats with a 10-day history of 6-h access to intravenous cocaine (0.25 mg/infusion). |
2024-10-10 |
2024-10-13 |
rat |
| Katelyn L Reeb, Sonita Wiah, Bhumiben P Patel, Stacia I Lewandowski, Ole V Mortensen, Joseph M Salvino, Scott M Rawls, Andréia C K Fontan. Positive allosteric modulation of glutamate transporter reduces cocaine-induced locomotion and expression of cocaine conditioned place preference in rats. European journal of pharmacology. 2024-09-30. PMID:39349114. |
positive allosteric modulation of glutamate transporter reduces cocaine-induced locomotion and expression of cocaine conditioned place preference in rats. |
2024-09-30 |
2024-10-03 |
rat |
| Joya Maser, Mary F Morrison, Helene Philogene Khalid, Ronan Cunningham, Daohai Yu, M Ingre Walters, Xiaoning Lu, Nicolas R Bol. Clavulanic Acid-Mediated Increases in Anterior Cingulate Glutamate Levels are Associated With Decreased Cocaine Craving and Brain Network Functional Connectivity Changes. Current therapeutic research, clinical and experimental. vol 101. 2024-07-24. PMID:39045086. |
clavulanic acid-mediated increases in anterior cingulate glutamate levels are associated with decreased cocaine craving and brain network functional connectivity changes. |
2024-07-24 |
2024-07-26 |
Not clear |
| Anna Maria Borruto, Claudia Calpe-López, Rainer Spanagel, Rick E Bernard. Conditional Deletion of the AMPA-GluA1 and NMDA-GluN1 Receptor Subunit Genes in Midbrain D1 Neurons does not Alter Cocaine Reward in Mice. Neuropharmacology. 2024-07-13. PMID:39002853. |
here, we investigated how midbrain ampar and nmdar function modulate cocaine reward-related behavior using mutant mouse lines lacking the glutamate receptor genes gria1 or grin1 in d1r-expressing neurons (glua1 |
2024-07-13 |
2024-07-16 |
mouse |
| Mark D Namba, Qiaowei Xie, Kyewon Park, Joshua G Jackson, Jacqueline M Barke. EcoHIV Infection Modulates the Effects of Cocaine Exposure Pattern and Abstinence on Cocaine Seeking and Neuroimmune Protein Expression in Male Mice. bioRxiv : the preprint server for biology. 2024-04-25. PMID:38659915. |
analysis of corticolimbic cx3cl1-cx3cr1 and glutamate receptor expression revealed alterations in medial prefrontal cortex (mpfc) cx3cl1 and nucleus accumbens (nac) glun2a receptors that correlated with cocaine seeking following daily cocaine exposure. |
2024-04-25 |
2024-04-28 |
mouse |
| Anna Luiza Diniz Lima, Emanuele Guimarães Silva, Pablo Leal Cardozo, Maria Carolina Machado da Silva, Suélyn Koerich, Fabíola Mara Ribeiro, Fabrício A Moreira, Luciene Bruno Vieir. Isradipine, an L-type calcium channel blocker, attenuates cocaine effects in mice by reducing central glutamate release. European journal of pharmacology. 2024-03-16. PMID:38492875. |
isradipine, an l-type calcium channel blocker, attenuates cocaine effects in mice by reducing central glutamate release. |
2024-03-16 |
2024-03-19 |
mouse |
| Yi He, Hui Shen, Guo-Hua Bi, Hai-Ying Zhang, Omar Soler-Cedeño, Hannah Alton, Yihong Yang, Zheng-Xiong X. GPR55 is expressed in glutamate neurons and functionally modulates drug taking and seeking in rats and mice. Translational psychiatry. vol 14. issue 1. 2024-02-19. PMID:38374108. |
here we report that gpr55 is predominantly found in glutamate neurons in the brain, and its activation reduces self-administration of cocaine and nicotine in rats and mice. |
2024-02-19 |
2024-02-22 |
mouse |
| Shailesh N Khatri, Hanaa Ulangkaya, Erin E Maher, Safiyah Sadek, Mei Hong, Andrea M Woodcox, William W Stoops, Cassandra D Gipso. Oxycodone withdrawal is associated with increased cocaine self-administration and aberrant accumbens glutamate plasticity in rats. Neuropharmacology. 2023-10-21. PMID:37865136. |
oxycodone withdrawal is associated with increased cocaine self-administration and aberrant accumbens glutamate plasticity in rats. |
2023-10-21 |
2023-11-08 |
rat |
| Shailesh N Khatri, Hanaa Ulangkaya, Erin E Maher, Safiyah Sadek, Mei Hong, Andrea M Woodcox, William W Stoops, Cassandra D Gipso. Oxycodone withdrawal is associated with increased cocaine self-administration and aberrant accumbens glutamate plasticity in rats. Neuropharmacology. 2023-10-21. PMID:37865136. |
preclinically, aberrant glutamate signaling within the nucleus accumbens core (nacore) occurs following use of cocaine or opioids, whereby medium spiny neurons (msns) rest in a potentiated or depotentiated state, respectively. |
2023-10-21 |
2023-11-08 |
rat |
| Shailesh N Khatri, Hanaa Ulangkaya, Erin E Maher, Safiyah Sadek, Mei Hong, Andrea M Woodcox, William W Stoops, Cassandra D Gipso. Oxycodone withdrawal is associated with increased cocaine self-administration and aberrant accumbens glutamate plasticity in rats. Neuropharmacology. 2023-10-21. PMID:37865136. |
however, it is not clear if cocaine can exacerbate opioid-induced changes in glutamate signaling. |
2023-10-21 |
2023-11-08 |
rat |
| Shailesh N Khatri, Hanaa Ulangkaya, Erin E Maher, Safiyah Sadek, Mei Hong, Andrea M Woodcox, William W Stoops, Cassandra D Gipso. Oxycodone withdrawal is associated with increased cocaine self-administration and aberrant accumbens glutamate plasticity in rats. Neuropharmacology. 2023-10-21. PMID:37865136. |
together, behavioral signs of oxycodone withdrawal may drive cocaine use and further dysregulate nacore glutamate signaling. |
2023-10-21 |
2023-11-08 |
rat |
| Sara L Kroll, Lea M Hulka, Ann-Kathrin Kexel, Matthias Vonmoos, Katrin H Preller, Valerie Treyer, Simon M Ametamey, Markus R Baumgartner, Carola Boost, Franziska Pahlisch, Cathrin Rohleder, F Markus Leweke, Boris B Quedno. Plasma endocannabinoids in cocaine dependence and their relation to cerebral metabotropic glutamate receptor 5 density. Translational psychiatry. vol 13. issue 1. 2023-10-19. PMID:37857616. |
plasma endocannabinoids in cocaine dependence and their relation to cerebral metabotropic glutamate receptor 5 density. |
2023-10-19 |
2023-11-08 |
human |
| Etna J E Engeli, Andrea G Russo, Sara Ponticorvo, Niklaus Zoelch, Andreas Hock, Lea M Hulka, Matthias Kirschner, Katrin H Preller, Erich Seifritz, Boris B Quednow, Fabrizio Esposito, Marcus Herdene. Accumbal-thalamic connectivity and associated glutamate alterations in human cocaine craving: A state-dependent rs-fMRI and NeuroImage. Clinical. vol 39. 2023-08-28. PMID:37639901. |
accumbal-thalamic connectivity and associated glutamate alterations in human cocaine craving: a state-dependent rs-fmri and craving is a core symptom of cocaine use disorder and a major factor for relapse risk. |
2023-08-28 |
2023-09-07 |
human |
| Danielle M Giangrasso, Kaliana M Veros, Maureen M Timm, Peter J West, Karen S Wilcox, Kristen A Keef. Glutamate dynamics in the dorsolateral striatum of rats with goal-directed and habitual cocaine-seeking behavior. Frontiers in molecular neuroscience. vol 16. 2023-05-30. PMID:37251646. |
together, these results suggest that glutamate clearance and release dynamics in the dls are largely unaltered by a history of cocaine self-administration on this established cocaine seeking-taking paradigm, regardless of whether the control over the cocaine seeking behavior was habitual or goal directed. |
2023-05-30 |
2023-08-14 |
rat |
| Shaun Yon-Seng Khoo, Anne-Noël Samah. Metabotropic glutamate group II receptor activation in the ventrolateral dorsal striatum suppresses incentive motivation for cocaine in rats. Psychopharmacology. 2023-04-15. PMID:37060471. |
metabotropic glutamate group ii receptor activation in the ventrolateral dorsal striatum suppresses incentive motivation for cocaine in rats. |
2023-04-15 |
2023-08-14 |
rat |
| Shaun Yon-Seng Khoo, Anne-Noël Samah. Metabotropic glutamate group II receptor activation in the ventrolateral dorsal striatum suppresses incentive motivation for cocaine in rats. Psychopharmacology. 2023-04-15. PMID:37060471. |
within the dorsal striatum, chronic cocaine use changes metabotropic glutamate type ii receptor (mglu |
2023-04-15 |
2023-08-14 |
rat |
| Javier R Mesa, Emily Carter, Yasmin Padovan-Hernandez, Lori A Knacksted. Alcohol consumption modulates prelimbic cortex response to cocaine following sequential cocaine and alcohol polysubstance use in the rat. Frontiers in pharmacology. vol 14. 2023-04-03. PMID:37007027. |
ceftriaxone, a beta-lactam antibiotic, reliably attenuates reinstatement of cocaine seeking in pre-clinical models by restoring glutamate homeostasis following cocaine self-administration but fails to do so when rats consume both cocaine and alcohol (cocaine + alcohol psu). |
2023-04-03 |
2023-08-14 |
rat |
| Claire M Corbett, Emily N D Miller, Jessica A Lowet. mGlu5 inhibition in the basolateral amygdala prevents estrous cycle-dependent changes in cue-induced cocaine seeking. Addiction neuroscience. vol 5. 2023-02-13. PMID:36778664. |
one region that contributes to both sex differences in behavioral responding and cue-induced cocaine seeking is the basolateral amygdala (bla), while one receptor known to play a critical role in mediating cocaine seeking behavior is metabotropic glutamate receptor 5 (mglu5). |
2023-02-13 |
2023-08-14 |
Not clear |
| Thi Dong Binh Tran, Hoan Nguyen, Erica Sodergren, Center For Systems Neurogenetics Of Addiction, Price E Dickson, Susan N Wright, Vivek M Philip, George M Weinstock, Elissa J Chesler, Yanjiao Zhou, Jason A Bubie. Microbial glutamate metabolism predicts intravenous cocaine self-administration in diversity outbred mice. Neuropharmacology. 2023-01-02. PMID:36592885. |
microbial glutamate metabolism predicts intravenous cocaine self-administration in diversity outbred mice. |
2023-01-02 |
2023-08-14 |
mouse |
| Thi Dong Binh Tran, Hoan Nguyen, Erica Sodergren, Center For Systems Neurogenetics Of Addiction, Price E Dickson, Susan N Wright, Vivek M Philip, George M Weinstock, Elissa J Chesler, Yanjiao Zhou, Jason A Bubie. Microbial glutamate metabolism predicts intravenous cocaine self-administration in diversity outbred mice. Neuropharmacology. 2023-01-02. PMID:36592885. |
functional analysis of the microbiome composition of a subset of mice suggested that gut-brain modules encoding glutamate metabolism genes are associated with the propensity to self-administer cocaine. |
2023-01-02 |
2023-08-14 |
mouse |