| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S E Robinson, P M Kunko, J A Smith, M J Wallace, Q Mo, J R Mahe. Extracellular aspartate concentration increases in nucleus accumbens after cocaine sensitization. European journal of pharmacology. vol 319. issue 1. 1997-04-14. PMID:9030894. |
involvement of excitatory amino acids in behavioral sensitization was assessed by comparing extracellular levels of aspartate and glutamate in the core of the nucleus accumbens in response to the first cocaine injection and the final cocaine challenge. |
1997-04-14 |
2023-08-12 |
rat |
| S E Robinson, P M Kunko, J A Smith, M J Wallace, Q Mo, J R Mahe. Extracellular aspartate concentration increases in nucleus accumbens after cocaine sensitization. European journal of pharmacology. vol 319. issue 1. 1997-04-14. PMID:9030894. |
increased nucleus accumbens extracellular concentration of aspartate, but not glutamate, was observed in rats exhibiting behavioral sensitization to cocaine. |
1997-04-14 |
2023-08-12 |
rat |
| K Bell, P W Kaliva. Context-specific cross-sensitization between systemic cocaine and intra-accumbens AMPA infusion in the rat. Psychopharmacology. vol 127. issue 4. 1997-03-25. PMID:8923575. |
two behavioral experiments were conducted in rats to evaluate the context-specificity of changes in nucleus accumbens glutamate transmission induced by systemic cocaine administration. |
1997-03-25 |
2023-08-12 |
human |
| K Bell, P W Kaliva. Context-specific cross-sensitization between systemic cocaine and intra-accumbens AMPA infusion in the rat. Psychopharmacology. vol 127. issue 4. 1997-03-25. PMID:8923575. |
at 2 weeks of withdrawal from daily cocaine injections (15 mg/kg, ip, daily x 7 days), subjects who had received cocaine in the test environment displayed a significantly greater motor response to intra-accumbens infusion of the glutamate receptor subtype-specific agonist, alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (ampa) than subjects who had received daily saline injections. |
1997-03-25 |
2023-08-12 |
human |
| S Shoji, D Simms, W C McDaniel, J P Gallaghe. Chronic cocaine enhances gamma-aminobutyric acid and glutamate release by altering presynaptic and not postsynaptic gamma-aminobutyric acidB receptors within the rat dorsolateral septal nucleus. The Journal of pharmacology and experimental therapeutics. vol 280. issue 1. 1997-02-10. PMID:8996190. |
chronic cocaine enhances gamma-aminobutyric acid and glutamate release by altering presynaptic and not postsynaptic gamma-aminobutyric acidb receptors within the rat dorsolateral septal nucleus. |
1997-02-10 |
2023-08-12 |
rat |
| S Shoji, D Simms, W C McDaniel, J P Gallaghe. Chronic cocaine enhances gamma-aminobutyric acid and glutamate release by altering presynaptic and not postsynaptic gamma-aminobutyric acidB receptors within the rat dorsolateral septal nucleus. The Journal of pharmacology and experimental therapeutics. vol 280. issue 1. 1997-02-10. PMID:8996190. |
we demonstrate that, within the dorsolateral septal nucleus of in vitro brain slices from animals that had received cocaine chronically in vivo for 14 or 28, but not 7, days, control of both inhibitory (gaba) and excitatory (glutamate) amino acid transmission is impaired, due to the combined diminished effectiveness of presynaptic gabab auto- and heteroreceptors. |
1997-02-10 |
2023-08-12 |
rat |
| M S Reid, S P Berge. Evidence for sensitization of cocaine-induced nucleus accumbens glutamate release. Neuroreport. vol 7. issue 7. 1996-12-10. PMID:8817559. |
cocaine-stimulated glutamate release in the nucleus accumbens was studied following chronic cocaine or saline pretreatment in order to determine whether this effect was sensitized in rats showing augmented dopamine release, locomotor and stereotypy responses. |
1996-12-10 |
2023-08-12 |
rat |
| M S Reid, S P Berge. Evidence for sensitization of cocaine-induced nucleus accumbens glutamate release. Neuroreport. vol 7. issue 7. 1996-12-10. PMID:8817559. |
following cocaine injection the increase in glutamate release, dopamine release, locomotor activity and stereotypy were greater in the cocaine-pretreated animals. |
1996-12-10 |
2023-08-12 |
rat |
| M S Reid, S P Berge. Evidence for sensitization of cocaine-induced nucleus accumbens glutamate release. Neuroreport. vol 7. issue 7. 1996-12-10. PMID:8817559. |
these results show that cocaine-stimulated glutamate release in the nucleus accumbens is sensitized following chronic cocaine pretreatment. |
1996-12-10 |
2023-08-12 |
rat |
| G R Poe, D A Nitz, D M Rector, M P Kristensen, R M Harpe. Concurrent reflectance imaging and microdialysis in the freely behaving cat. Journal of neuroscience methods. vol 65. issue 2. 1996-10-24. PMID:8740591. |
we applied this method to the dorsal hippocampus of freely behaving cats to (1) measure extracellular glutamate and reflectance variations across a sleep-waking cycle, (2) assess spatially coherent neural activity changes accompanying local perfusion of cocaine and (3) measure local changes in cell volume induced by infusion of hyper- and hypo-osmotic solutions. |
1996-10-24 |
2023-08-12 |
cat |
| R C Pierce, K Bell, P Duffy, P W Kaliva. Repeated cocaine augments excitatory amino acid transmission in the nucleus accumbens only in rats having developed behavioral sensitization. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 4. 1996-09-18. PMID:8778304. |
(3) the extracellular content of glutamate was measured after a cocaine challenge given at 21 d of withdrawal. |
1996-09-18 |
2023-08-12 |
rat |
| R C Pierce, K Bell, P Duffy, P W Kaliva. Repeated cocaine augments excitatory amino acid transmission in the nucleus accumbens only in rats having developed behavioral sensitization. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 4. 1996-09-18. PMID:8778304. |
cocaine elevated the levels of glutamate in the core of sensitized rats, but not of nonsensitized or control rats. |
1996-09-18 |
2023-08-12 |
rat |
| L W Fitzgerald, J Ortiz, A G Hamedani, E J Nestle. Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: common adaptations among cross-sensitizing agents. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 1. 1996-06-03. PMID:8613793. |
we therefore examined the effect of repeated cocaine treatment on glutamate receptor subunit expression in central dopamine (da) pathways implicated in many of cocaine's behavioral actions. |
1996-06-03 |
2023-08-12 |
rat |
| Y Itzha. Cocaine kindling in mice. Responses to N-methyl-D,L-aspartate (NMDLA) and L-arginine. Molecular neurobiology. vol 11. issue 1-3. 1996-03-07. PMID:8561964. |
previous studies proposed the involvement of the n-methyl-d-aspartate (nmda) type of glutamate receptors in the development of sensitization to the convulsive effect of cocaine (cocaine kindling). |
1996-03-07 |
2023-08-12 |
mouse |
| J A Smith, Q Mo, H Guo, P M Kunko, S E Robinso. Cocaine increases extraneuronal levels of aspartate and glutamate in the nucleus accumbens. Brain research. vol 683. issue 2. 1995-11-21. PMID:7552364. |
cocaine increases extraneuronal levels of aspartate and glutamate in the nucleus accumbens. |
1995-11-21 |
2023-08-12 |
rat |
| J A Smith, Q Mo, H Guo, P M Kunko, S E Robinso. Cocaine increases extraneuronal levels of aspartate and glutamate in the nucleus accumbens. Brain research. vol 683. issue 2. 1995-11-21. PMID:7552364. |
local perfusion with ca(2+)-free buffer reduced the increase of extracellular aspartate and glutamate in rats injected with 30 mg/kg cocaine. |
1995-11-21 |
2023-08-12 |
rat |
| K Shimosato, R J Marley, T Sait. Differential effects of NMDA receptor and dopamine receptor antagonists on cocaine toxicities. Pharmacology, biochemistry, and behavior. vol 51. issue 4. 1995-10-19. PMID:7675859. |
the present study examined the involvement of the n-methyl-d-aspartate (nmda) subtype of the glutamate receptors and the dopamine d1 and d2 receptors in seizure activity and lethality observed following single and repeated injections of cocaine in ddy mice. |
1995-10-19 |
2023-08-12 |
mouse |
| P W Kalivas, P Duff. D1 receptors modulate glutamate transmission in the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 7 Pt 2. 1995-08-30. PMID:7623160. |
these data indicate that the stimulation of d1 receptors in the ventral tegmental area increases the release of glutamate and that increasing extracellular levels of somatodendritic dopamine by systemic cocaine can mimic this effect. |
1995-08-30 |
2023-08-12 |
Not clear |
| S E Robinson, J R Maher, K P McDowell, P M Kunk. Effects of cocaine and the cocaine analog CFT on glutamatergic neurons. Pharmacology, biochemistry, and behavior. vol 50. issue 4. 1995-08-24. PMID:7617711. |
the effects of cocaine and the cocaine analog methyl-3-beta-(p-fluorophenyl)-1 alpha h, 5 alpha h-tropane-2b-carboxylate (cft) on glutamate turnover rate were studied in the nucleus accumbens, striatum, frontal cortex, and parietal-cingulate cortex of the rat, using neurotransmitter turnover rate as an estimate of the activity of the glutamatergic neurons. |
1995-08-24 |
2023-08-12 |
rat |
| S E Robinson, J R Maher, K P McDowell, P M Kunk. Effects of cocaine and the cocaine analog CFT on glutamatergic neurons. Pharmacology, biochemistry, and behavior. vol 50. issue 4. 1995-08-24. PMID:7617711. |
both cocaine [15 or 30 mg/kg, intraperitoneally (ip)] and cft (2.2 mg/kg, ip) increased glutamate turnover in the nucleus accumbens, although the time course of their actions differed. |
1995-08-24 |
2023-08-12 |
rat |