| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Bell, P Duffy, P W Kaliva. Context-specific enhancement of glutamate transmission by cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 3. 2000-10-11. PMID:10942857. |
the repeated injection of cocaine causes an increase in the capacity of a subsequent acute injection to elevate extracellular glutamate levels in the nucleus accumbens, and the present study sought to determine if the elevation in extracellular glutamate is regulated by the pairing of environmental stimuli with drug administration. |
2000-10-11 |
2023-08-12 |
rat |
| K Bell, P Duffy, P W Kaliva. Context-specific enhancement of glutamate transmission by cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 3. 2000-10-11. PMID:10942857. |
moreover, only in the cocaine-paired group did the cocaine injection elevate extracellular glutamate. |
2000-10-11 |
2023-08-12 |
rat |
| K Bell, P Duffy, P W Kaliva. Context-specific enhancement of glutamate transmission by cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 3. 2000-10-11. PMID:10942857. |
repeated administration of cocaine also produces an enduring increase in the motor stimulant response to an acute cocaine injection and it was previously found that administration of the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid and kainic acid glutamate receptor antagonist 6-cyano-7-nitroquinoxaline-2, 3-dione inhibited the sensitized, but not the acute motor, response to cocaine. |
2000-10-11 |
2023-08-12 |
rat |
| K Bell, P Duffy, P W Kaliva. Context-specific enhancement of glutamate transmission by cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 3. 2000-10-11. PMID:10942857. |
these data support a hypothesis that environmental stimuli previously associated with daily cocaine administration can modulate glutamate transmission in the nucleus accumbens in a manner affecting cocaine-induced behavior. |
2000-10-11 |
2023-08-12 |
rat |
| V Neugebauer, F Zinebi, R Russell, J P Gallagher, P Shinnick-Gallaghe. Cocaine and kindling alter the sensitivity of group II and III metabotropic glutamate receptors in the central amygdala. Journal of neurophysiology. vol 84. issue 2. 2000-09-14. PMID:10938303. |
cocaine and kindling alter the sensitivity of group ii and iii metabotropic glutamate receptors in the central amygdala. |
2000-09-14 |
2023-08-12 |
rat |
| V Neugebauer, F Zinebi, R Russell, J P Gallagher, P Shinnick-Gallaghe. Cocaine and kindling alter the sensitivity of group II and III metabotropic glutamate receptors in the central amygdala. Journal of neurophysiology. vol 84. issue 2. 2000-09-14. PMID:10938303. |
the influence of kindling and chronic cocaine exposure in vivo was examined in vitro on the modulation of synaptic transmission by group ii and iii metabotropic glutamate receptors using whole cell voltage-clamp recordings of central amygdala (cea) neurons. |
2000-09-14 |
2023-08-12 |
rat |
| E A Kiyatkin, G V Rebe. Dopamine-independent action of cocaine on striatal and accumbal neurons. The European journal of neuroscience. vol 12. issue 5. 2000-07-24. PMID:10792456. |
whereas sch-23390 alone had a weak attenuating effect, no effect and even a slight enhancement of responses to cocaine occurred in fast-firing glutamate (glu)-stimulated units after the combined blockade of d1 and d2 receptors. |
2000-07-24 |
2023-08-12 |
rat |
| K R De Leon, M S Todtenkopf, J R Stella. An examination of glutamate decarboxylase(65) immunoreactive puncta with respect to rat ventral pallidum neurons after repeated cocaine administration. Neuroscience letters. vol 284. issue 1-2. 2000-07-03. PMID:10771164. |
an examination of glutamate decarboxylase(65) immunoreactive puncta with respect to rat ventral pallidum neurons after repeated cocaine administration. |
2000-07-03 |
2023-08-12 |
rat |
| K R De Leon, M S Todtenkopf, J R Stella. An examination of glutamate decarboxylase(65) immunoreactive puncta with respect to rat ventral pallidum neurons after repeated cocaine administration. Neuroscience letters. vol 284. issue 1-2. 2000-07-03. PMID:10771164. |
the present study investigated glutamate decarboxylase-65 (gad(65)) immunoreactivity in the rat ventral pallidum after repeated cocaine administration. |
2000-07-03 |
2023-08-12 |
rat |
| R L Brackett, B Pouw, J F Blyden, M Nour, R R Matsumot. Prevention of cocaine-induced convulsions and lethality in mice: effectiveness of targeting different sites on the NMDA receptor complex. Neuropharmacology. vol 39. issue 3. 2000-05-16. PMID:10698007. |
the glutamate release inhibitor riluzole failed to prevent both the convulsions and lethality induced by cocaine. |
2000-05-16 |
2023-08-12 |
mouse |
| C D Fiorillo, J T William. Selective inhibition by adenosine of mGluR IPSPs in dopamine neurons after cocaine treatment. Journal of neurophysiology. vol 83. issue 3. 2000-04-11. PMID:10712458. |
this suggests that the elevated adenosine tone induced by cocaine treatment acts preferentially on glutamate terminals. |
2000-04-11 |
2023-08-12 |
rat |
| L C Winther, R Saleem, E F McCance-Katz, M I Rosen, F A Hameedi, H R Pearsall, P I Jatlow, T R Kosten, S W Wood. Effects of lamotrigine on behavioral and cardiovascular responses to cocaine in human subjects. The American journal of drug and alcohol abuse. vol 26. issue 1. 2000-04-11. PMID:10718163. |
we evaluated the effects of acute pretreatment with lamotrigine, a putative glutamate release inhibitor, on the physiological and behavioral responses to intranasal cocaine in cocaine-dependent volunteers (n = 8). |
2000-04-11 |
2023-08-12 |
human |
| B Pouw, M Nour, R R Matsumot. Effects of AMPA/kainate glutamate receptor antagonists on cocaine-induced convulsions and lethality in mice. European journal of pharmacology. vol 386. issue 2-3. 2000-02-29. PMID:10618468. |
since glutamate is the primary neurotransmitter for nmda receptors, pharmacological interventions to lower glutamatergic activity through non-nmda ionotropic receptor-mediated mechanisms were evaluated for their ability to prevent the convulsive and lethal effects of cocaine. |
2000-02-29 |
2023-08-12 |
mouse |
| Y Itzhak, J L Marti. Cocaine-induced kindling is associated with elevated NMDA receptor binding in discrete mouse brain regions. Neuropharmacology. vol 39. issue 1. 2000-02-18. PMID:10665817. |
the present study was undertaken to investigate the involvement of n-methyl-d-aspartate (nmda) type of glutamate receptors in the induction and maintenance of kindling generated by daily cocaine (35 mg/kg) injections to swiss webster mice. |
2000-02-18 |
2023-08-12 |
mouse |
| Y Li, X T Hu, T G Berney, A J Vartanian, C D Stine, M E Wolf, F J Whit. Both glutamate receptor antagonists and prefrontal cortex lesions prevent induction of cocaine sensitization and associated neuroadaptations. Synapse (New York, N.Y.). vol 34. issue 3. 1999-12-10. PMID:10523754. |
both glutamate receptor antagonists and prefrontal cortex lesions prevent induction of cocaine sensitization and associated neuroadaptations. |
1999-12-10 |
2023-08-12 |
rat |
| Y Li, X T Hu, T G Berney, A J Vartanian, C D Stine, M E Wolf, F J Whit. Both glutamate receptor antagonists and prefrontal cortex lesions prevent induction of cocaine sensitization and associated neuroadaptations. Synapse (New York, N.Y.). vol 34. issue 3. 1999-12-10. PMID:10523754. |
to determine whether the relevant glutamate receptors were under regulation by medial prefrontal cortex (mpfc) eaa efferents, we next lesioned the mpfc bilaterally with ibotenic acid at least 7 days before repeated cocaine treatment began. |
1999-12-10 |
2023-08-12 |
rat |
| Y Li, X T Hu, T G Berney, A J Vartanian, C D Stine, M E Wolf, F J Whit. Both glutamate receptor antagonists and prefrontal cortex lesions prevent induction of cocaine sensitization and associated neuroadaptations. Synapse (New York, N.Y.). vol 34. issue 3. 1999-12-10. PMID:10523754. |
our findings indicate that glutamate transmission from mpfc to the mesoaccumbens da system is critical for the induction of cocaine sensitization and its cellular correlates. |
1999-12-10 |
2023-08-12 |
rat |
| J L Cornish, P Duffy, P W Kaliva. A role for nucleus accumbens glutamate transmission in the relapse to cocaine-seeking behavior. Neuroscience. vol 93. issue 4. 1999-12-09. PMID:10501460. |
this study investigated the effect of ionotropic glutamate receptor agonist or antagonist administration into the nucleus accumbens on the maintenance of cocaine self-administration and the reinstatement of cocaine-seeking behavior. |
1999-12-09 |
2023-08-12 |
Not clear |
| J L Cornish, P Duffy, P W Kaliva. A role for nucleus accumbens glutamate transmission in the relapse to cocaine-seeking behavior. Neuroscience. vol 93. issue 4. 1999-12-09. PMID:10501460. |
the stimulation of alpha-amino-3-hydroxy-5-methylisoxazole-4-proprionic acid or n-methyl-d-aspartate glutamate receptors in the nucleus accumbens with either alpha-amino-3-hydroxy-5-methylisoxazole-4-proprionic acid or 1-aminocyclobutane-cis-1,3-dicarboxylic acid, respectively, decreased the number of cocaine-reinforced responses, suggesting an enhancement in the rewarding properties of cocaine. |
1999-12-09 |
2023-08-12 |
Not clear |
| J L Cornish, P Duffy, P W Kaliva. A role for nucleus accumbens glutamate transmission in the relapse to cocaine-seeking behavior. Neuroscience. vol 93. issue 4. 1999-12-09. PMID:10501460. |
these results suggest that stimulation of glutamate receptors in the nucleus accumbens augments the reinforcing effect of cocaine, yet glutamate transmission is not required to maintain cocaine self-administration. |
1999-12-09 |
2023-08-12 |
Not clear |