| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Behnam Ghasemzadeh, Lindsay K Permenter, Russell Lake, Paul F Worley, Peter W Kaliva. Homer1 proteins and AMPA receptors modulate cocaine-induced behavioural plasticity. The European journal of neuroscience. vol 18. issue 6. 2003-12-05. PMID:14511343. |
to examine this possibility, rats were pretreated in the accumbens with drugs to block ampa/kainate, n-methyl-d-aspartate, group 1 metabotropic glutamate or dopamine receptors prior to each daily injection of cocaine. |
2003-12-05 |
2023-08-12 |
rat |
| Maria Collin, Matilda Bäckberg, Marie-Louise Ovesjö, Gilberto Fisone, Robert H Edwards, Fumino Fujiyama, Björn Meiste. Plasma membrane and vesicular glutamate transporter mRNAs/proteins in hypothalamic neurons that regulate body weight. The European journal of neuroscience. vol 18. issue 5. 2003-10-23. PMID:12956725. |
eaat3-like immunoreactivity (-li) was demonstrated in glutamate, neuropeptide y (npy), agouti-related peptide (agrp), pro-opiomelanocortin (pomc), cocaine and amphetamine-regulated transcript (cart), melanin-concentrating hormone and orexin-immunoreactive (-ir) neurons. |
2003-10-23 |
2023-08-12 |
mouse |
| Lloyd J Forma. The effect of cannabinoid receptor antagonism with SR141716A on antinociception induced by cocaine and the NMDA receptor antagonist, MK-801. Brain research bulletin. vol 61. issue 2. 2003-09-02. PMID:12832001. |
in the rat, antinociception of supraspinal origin is observed in response to administration of cocaine or an antagonist of the nmda receptor for glutamate. |
2003-09-02 |
2023-08-12 |
rat |
| David A Baker, Krista McFarland, Russell W Lake, Hui Shen, Xing-Chun Tang, Shigenobu Toda, Peter W Kaliva. Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse. Nature neuroscience. vol 6. issue 7. 2003-08-14. PMID:12778052. |
withdrawal from repeated cocaine reduced in vivo extracellular glutamate in the nucleus accumbens of rats by decreasing the exchange of extracellular cystine for intracellular glutamate. |
2003-08-14 |
2023-08-12 |
human |
| David A Baker, Krista McFarland, Russell W Lake, Hui Shen, Xing-Chun Tang, Shigenobu Toda, Peter W Kaliva. Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse. Nature neuroscience. vol 6. issue 7. 2003-08-14. PMID:12778052. |
to determine if the reduction in nonvesicular glutamate release is a mediator of relapse, we examined cocaine-primed reinstatement of drug seeking after cocaine self-administration was stopped. |
2003-08-14 |
2023-08-12 |
human |
| G Hotsenpiller, M E Wol. Baclofen attenuates conditioned locomotion to cues associated with cocaine administration and stabilizes extracellular glutamate levels in rat nucleus accumbens. Neuroscience. vol 118. issue 1. 2003-08-13. PMID:12676144. |
baclofen attenuates conditioned locomotion to cues associated with cocaine administration and stabilizes extracellular glutamate levels in rat nucleus accumbens. |
2003-08-13 |
2023-08-12 |
human |
| G Hotsenpiller, M E Wol. Baclofen attenuates conditioned locomotion to cues associated with cocaine administration and stabilizes extracellular glutamate levels in rat nucleus accumbens. Neuroscience. vol 118. issue 1. 2003-08-13. PMID:12676144. |
a better understanding of interactions between gaba and glutamate transmission in the nac may lead to the development of pharmacotherapies for cocaine craving. |
2003-08-13 |
2023-08-12 |
human |
| Vadim Yuferov, Thomas Kroslak, K Steven Laforge, Yan Zhou, Ann Ho, Mary Jeanne Kree. Differential gene expression in the rat caudate putamen after "binge" cocaine administration: advantage of triplicate microarray analysis. Synapse (New York, N.Y.). vol 48. issue 4. 2003-07-25. PMID:12687634. |
acute "binge" cocaine also increased mrna levels for glutamate receptor glur2, dopamine receptor d1, and a number of phosphatases. |
2003-07-25 |
2023-08-12 |
rat |
| M-C Peakman, C Colby, L I Perrotti, P Tekumalla, T Carle, P Ulery, J Chao, C Duman, C Steffen, L Monteggia, M R Allen, J L Stock, R S Duman, J D McNeish, M Barrot, D W Self, E J Nestler, E Schaeffe. Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine. Brain research. vol 970. issue 1-2. 2003-07-08. PMID:12706249. |
however, expression of deltac-jun in adult mice blocked the ability of chronic cocaine administration to induce three known targets for ap-1 in the nac: the ampa glutamate receptor subunit glur2, the cyclin-dependent protein kinase cdk5, and the transcription factor nuclear factor-kappab (nfkappab), without affecting several other proteins examined for comparison. |
2003-07-08 |
2023-08-12 |
mouse |
| Wen-Xue Tang, Wendy H Fasulo, Deborah C Mash, Scott E Hemb. Molecular profiling of midbrain dopamine regions in cocaine overdose victims. Journal of neurochemistry. vol 85. issue 4. 2003-06-18. PMID:12716423. |
the present results indicate that selective alterations of creb and certain ionotropic glutamate receptor (iglur) subtypes appear to be associated with chronic cocaine use in humans in a region-specific manner. |
2003-06-18 |
2023-08-12 |
Not clear |
| Zheng-Xiong Xi, Sammanda Ramamoorthy, Hui Shen, Russell Lake, Devadoss J Samuvel, Peter W Kaliva. GABA transmission in the nucleus accumbens is altered after withdrawal from repeated cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 8. 2003-05-30. PMID:12716959. |
repeated cocaine causes enduring changes in dopamine and glutamate transmission in the nucleus accumbens, and dopamine and glutamate terminals synapse on gabaergic accumbens neurons. |
2003-05-30 |
2023-08-12 |
human |
| Krista McFarland, Christopher C Lapish, Peter W Kaliva. Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 8. 2003-05-30. PMID:12716962. |
when extinguished cocaine self-administration behavior was reinstated by a cocaine-priming injection, extracellular levels of both dopamine and glutamate were elevated in the nucleus accumbens. |
2003-05-30 |
2023-08-12 |
human |
| Krista McFarland, Christopher C Lapish, Peter W Kaliva. Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 8. 2003-05-30. PMID:12716962. |
the increase in glutamate was not accounted for simply by the act of lever pressing itself, because the cocaine self-administration group still demonstrated elevated glutamate when the levers were withdrawn from the operant chamber. |
2003-05-30 |
2023-08-12 |
human |
| Nobuyoshi Suto, Lauren M Tanabe, Jennifer D Austin, Elizabeth Creekmore, Paul Vezin. Previous exposure to VTA amphetamine enhances cocaine self-administration under a progressive ratio schedule in an NMDA, AMPA/kainate, and metabotropic glutamate receptor-dependent manner. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 4. 2003-05-29. PMID:12655307. |
previous exposure to vta amphetamine enhances cocaine self-administration under a progressive ratio schedule in an nmda, ampa/kainate, and metabotropic glutamate receptor-dependent manner. |
2003-05-29 |
2023-08-12 |
rat |
| J E Smith, T R Koves, C C. Brain neurotransmitter turnover rates during rat intravenous cocaine self-administration. Neuroscience. vol 117. issue 2. 2003-05-21. PMID:12614686. |
the turnover rates of dopamine, norepinephrine, serotonin, aspartate, glutamate and gaba were measured in 27 brain regions of rats self-administering cocaine and in yoked cocaine- and yoked vehicle-infused controls using radioactive pulse-labeling procedures to identify brain neuronal systems underlying self-administration. |
2003-05-21 |
2023-08-12 |
rat |
| J E Smith, T R Koves, C C. Brain neurotransmitter turnover rates during rat intravenous cocaine self-administration. Neuroscience. vol 117. issue 2. 2003-05-21. PMID:12614686. |
changes in the activity of heretofore unrecognized dopamine, norepinephrine, serotonin, glutamate and gaba innervations of the forebrain specific to cocaine self-administration were found. |
2003-05-21 |
2023-08-12 |
rat |
| Gregory Hotsenpiller, Marina E Wol. Extracellular glutamate levels in prefrontal cortex during the expression of associative responses to cocaine related stimuli. Neuropharmacology. vol 43. issue 8. 2003-03-28. PMID:12527471. |
we conducted studies to examine the potential role of glutamate in the prefrontal cortex (pfc) during conditioned responses to stimuli (flashing light and metronome) previously associated with cocaine administration. |
2003-03-28 |
2023-08-12 |
human |
| Gregory Hotsenpiller, Marina E Wol. Extracellular glutamate levels in prefrontal cortex during the expression of associative responses to cocaine related stimuli. Neuropharmacology. vol 43. issue 8. 2003-03-28. PMID:12527471. |
then, we used microdialysis to examine extracellular levels of glutamate in the pfc in response to presentation of the conditioned stimuli alone and challenge with cocaine in the presence of the conditioned stimuli. |
2003-03-28 |
2023-08-12 |
human |
| B Kozell, K Meshu. Alterations in nerve terminal glutamate immunoreactivity in the nucleus accumbens and ventral tegmental area following single and repeated doses of cocaine. Psychopharmacology. vol 165. issue 4. 2003-03-20. PMID:12459930. |
alterations in nerve terminal glutamate immunoreactivity in the nucleus accumbens and ventral tegmental area following single and repeated doses of cocaine. |
2003-03-20 |
2023-08-12 |
Not clear |
| B Kozell, K Meshu. Alterations in nerve terminal glutamate immunoreactivity in the nucleus accumbens and ventral tegmental area following single and repeated doses of cocaine. Psychopharmacology. vol 165. issue 4. 2003-03-20. PMID:12459930. |
previous studies have demonstrated that sensitization to repeated doses of cocaine results in prolonged changes in glutamate transmission. |
2003-03-20 |
2023-08-12 |
Not clear |