| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenxue Tang, Michael Wesley, Willard M Freeman, Bill Liang, Scott E Hemb. Alterations in ionotropic glutamate receptor subunits during binge cocaine self-administration and withdrawal in rats. Journal of neurochemistry. vol 89. issue 4. 2004-06-04. PMID:15140200. |
previous studies have examined ionotropic glutamate receptor (iglur) subunit protein level changes following acute and chronic experimenter-administered cocaine or after withdrawal periods from experimenter-administered cocaine. |
2004-06-04 |
2023-08-12 |
rat |
| Krista McFarland, Susan B Davidge, Christopher C Lapish, Peter W Kaliva. Limbic and motor circuitry underlying footshock-induced reinstatement of cocaine-seeking behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 7. 2004-05-04. PMID:14973230. |
also supporting the idea of a cea-vta-motor circuit in stress-induced reinstatement of cocaine seeking, inactivation of the pfcd was shown to block stress-induced glutamate release within the nacore while concurrently inhibiting reinstatement responding. |
2004-05-04 |
2023-08-12 |
Not clear |
| L B Kozell, C K Meshu. Nerve terminal glutamate immunoreactivity in the rat nucleus accumbens and ventral tegmental area after a short withdrawal from cocaine. Synapse (New York, N.Y.). vol 51. issue 4. 2004-03-24. PMID:14696010. |
nerve terminal glutamate immunoreactivity in the rat nucleus accumbens and ventral tegmental area after a short withdrawal from cocaine. |
2004-03-24 |
2023-08-12 |
rat |
| L B Kozell, C K Meshu. Nerve terminal glutamate immunoreactivity in the rat nucleus accumbens and ventral tegmental area after a short withdrawal from cocaine. Synapse (New York, N.Y.). vol 51. issue 4. 2004-03-24. PMID:14696010. |
cocaine administration has been shown to alter glutamate transmission in numerous studies. |
2004-03-24 |
2023-08-12 |
rat |
| L B Kozell, C K Meshu. Nerve terminal glutamate immunoreactivity in the rat nucleus accumbens and ventral tegmental area after a short withdrawal from cocaine. Synapse (New York, N.Y.). vol 51. issue 4. 2004-03-24. PMID:14696010. |
using quantitative electron microscopic immunogold labeling, our laboratory has previously reported that nerve terminal glutamate immunoreactivity is transiently altered following cocaine administration. |
2004-03-24 |
2023-08-12 |
rat |
| L B Kozell, C K Meshu. Nerve terminal glutamate immunoreactivity in the rat nucleus accumbens and ventral tegmental area after a short withdrawal from cocaine. Synapse (New York, N.Y.). vol 51. issue 4. 2004-03-24. PMID:14696010. |
the present study was undertaken to examine presynaptic nerve terminal glutamate immunoreactivity at shorter time points after withdrawal from cocaine. |
2004-03-24 |
2023-08-12 |
rat |
| L B Kozell, C K Meshu. Nerve terminal glutamate immunoreactivity in the rat nucleus accumbens and ventral tegmental area after a short withdrawal from cocaine. Synapse (New York, N.Y.). vol 51. issue 4. 2004-03-24. PMID:14696010. |
a single dose of cocaine did not alter the density of presynaptic nerve terminal glutamate immunoreactivity in the nucleus accumbens (nac) or ventral tegmental area (vta). |
2004-03-24 |
2023-08-12 |
rat |
| L B Kozell, C K Meshu. Nerve terminal glutamate immunoreactivity in the rat nucleus accumbens and ventral tegmental area after a short withdrawal from cocaine. Synapse (New York, N.Y.). vol 51. issue 4. 2004-03-24. PMID:14696010. |
the density of nerve terminal glutamate immunoreactivity in the shell, but not the core, was significantly increased in the animals receiving repeated cocaine. |
2004-03-24 |
2023-08-12 |
rat |
| L B Kozell, C K Meshu. Nerve terminal glutamate immunoreactivity in the rat nucleus accumbens and ventral tegmental area after a short withdrawal from cocaine. Synapse (New York, N.Y.). vol 51. issue 4. 2004-03-24. PMID:14696010. |
the finding that repeated cocaine treatment increased glutamate nerve terminal immunolabeling within the nucleus accumbens shell, but not the core, supports the hypothesis that glutamate synapses in the core and shell are differentially sensitive to repeated cocaine administration. |
2004-03-24 |
2023-08-12 |
rat |
| Yun Liu, Hai-Rong He, Jian-Hua Ding, Bing Gu, Hai Wang, Gang H. Iptkalim inhibits cocaine challenge-induced enhancement of dopamine levels in nucleus accumbens and striatum of rats by up-regulating Kir6.1 and Kir6.2 mRNA expression. Acta pharmacologica Sinica. vol 24. issue 6. 2004-03-22. PMID:12791178. |
to investigate the effect and mechanism of novel atp-sensitive potassium channel opener (kco) iptkalim (ipt) on acute and cocaine challenge-induced alterations in the levels of dopamine (da) and glutamate (glu) from nucleus accumbens (nac), striatum, and prefrontal cortex (pfc) in rats. |
2004-03-22 |
2023-08-12 |
rat |
| D A Baker, H Shen, P W Kaliva. Cystine/glutamate exchange serves as the source for extracellular glutamate: modifications by repeated cocaine administration. Amino acids. vol 23. issue 1-3. 2004-02-26. PMID:12373531. |
cystine/glutamate exchange serves as the source for extracellular glutamate: modifications by repeated cocaine administration. |
2004-02-26 |
2023-08-12 |
Not clear |
| D A Baker, H Shen, P W Kaliva. Cystine/glutamate exchange serves as the source for extracellular glutamate: modifications by repeated cocaine administration. Amino acids. vol 23. issue 1-3. 2004-02-26. PMID:12373531. |
repeated administration of cocaine lowers the basal extracellular levels of glutamate in the nucleus accumbens as measured by microdialysis. |
2004-02-26 |
2023-08-12 |
Not clear |
| Peter W Kalivas, Krista McFarland, Scott Bowers, Karer Szumlinski, Zheng-Xiong Xi, David Bake. Glutamate transmission and addiction to cocaine. Annals of the New York Academy of Sciences. vol 1003. 2004-02-13. PMID:14684444. |
glutamate transmission and addiction to cocaine. |
2004-02-13 |
2023-08-12 |
mouse |
| Peter W Kalivas, Krista McFarland, Scott Bowers, Karer Szumlinski, Zheng-Xiong Xi, David Bake. Glutamate transmission and addiction to cocaine. Annals of the New York Academy of Sciences. vol 1003. 2004-02-13. PMID:14684444. |
a variety of data point to the possibility that neuroadaptations in glutamate transmission are produced by repeated exposure to cocaine that result in the expression of behaviors characteristic of addiction, such as craving and relapse. |
2004-02-13 |
2023-08-12 |
mouse |
| Peter W Kalivas, Krista McFarland, Scott Bowers, Karer Szumlinski, Zheng-Xiong Xi, David Bake. Glutamate transmission and addiction to cocaine. Annals of the New York Academy of Sciences. vol 1003. 2004-02-13. PMID:14684444. |
in this report, four adaptations produced by withdrawal from repeated cocaine are described that may regulate the release of glutamate underlying reinstatement of drug-seeking resulted. |
2004-02-13 |
2023-08-12 |
mouse |
| Peter W Kalivas, Krista McFarland, Scott Bowers, Karer Szumlinski, Zheng-Xiong Xi, David Bake. Glutamate transmission and addiction to cocaine. Annals of the New York Academy of Sciences. vol 1003. 2004-02-13. PMID:14684444. |
(3) metobotropic glutamate receptor function is diminished after repeated cocaine administration that results in reduced regulation of glutamate release. |
2004-02-13 |
2023-08-12 |
mouse |
| Peter W Kalivas, Krista McFarland, Scott Bowers, Karer Szumlinski, Zheng-Xiong Xi, David Bake. Glutamate transmission and addiction to cocaine. Annals of the New York Academy of Sciences. vol 1003. 2004-02-13. PMID:14684444. |
these adaptations are hypothesized to facilitate glutamate release in response to a cocaine injection or acute stress and lead to the reinstatement of drug-seeking behavior. |
2004-02-13 |
2023-08-12 |
mouse |
| Charles Dackis, Charles O'Brie. Glutamatergic agents for cocaine dependence. Annals of the New York Academy of Sciences. vol 1003. 2004-02-13. PMID:14684456. |
we review the involvement of glutamate in reward-related circuits, the acute and chronic effects of cocaine on these pathways, and glutamatergic mechanisms that contribute to the neurobiology of cocaine dependence. |
2004-02-13 |
2023-08-12 |
Not clear |
| P J Kenny, N E Paterson, B Boutrel, S Semenova, A A Harrison, F Gasparini, G F Koob, P D Skoubis, A Marko. Metabotropic glutamate 5 receptor antagonist MPEP decreased nicotine and cocaine self-administration but not nicotine and cocaine-induced facilitation of brain reward function in rats. Annals of the New York Academy of Sciences. vol 1003. 2004-02-13. PMID:14684476. |
metabotropic glutamate 5 receptor antagonist mpep decreased nicotine and cocaine self-administration but not nicotine and cocaine-induced facilitation of brain reward function in rats. |
2004-02-13 |
2023-08-12 |
rat |
| Tamaki Hayase, Yoshiko Yamamoto, Keiichi Yamamot. Toxic cocaine- and convulsant-induced modification of forced swimming behaviors and their interaction with ethanol: comparison with immobilization stress. BMC pharmacology. vol 2. 2004-01-14. PMID:12425723. |
since toxic convulsion-inducing drugs related to dopamine [cocaine (coc)], benzodiazepine [methyl 6,7-dimethoxy-4-ethyl-beta-carboline-carboxylate (dmcm)], gamma-aminobutyric acid (gaba) [bicuculline (bic)], and glutamate [n-methyl-d-aspartate (nmda)] receptors can function as stressors, the present study compared their effects on the forced swimming behaviors with the effects of immobilization stress (im) in rats. |
2004-01-14 |
2023-08-12 |
rat |