| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Megan M Moran, Krista McFarland, Roberto I Melendez, Peter W Kalivas, Jeremy K Seaman. Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 27. 2006-02-28. PMID:16000629. |
cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking. |
2006-02-28 |
2023-08-12 |
rat |
| Megan M Moran, Krista McFarland, Roberto I Melendez, Peter W Kalivas, Jeremy K Seaman. Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 27. 2006-02-28. PMID:16000629. |
withdrawal from chronic cocaine reduces extracellular glutamate levels in the nucleus accumbens by decreasing cystine/glutamate exchange (xc-). |
2006-02-28 |
2023-08-12 |
rat |
| Shirzad Jenab, Eugene D Festa, Arbi Nazarian, Hui Bing K Wu, Wei Lun Sun, Ruhal Hazim, Scott J Russo, Vanya Quinones-Jena. Cocaine induction of ERK proteins in dorsal striatum of Fischer rats. Brain research. Molecular brain research. vol 142. issue 2. 2006-02-21. PMID:16271798. |
cocaine is an addictive psychostimulant that induces fos and opioid gene expression by activating the dopamine receptors and the pka pathways in dopamine d1 and a glutamate nmda-dependent mechanisms in the striatum. |
2006-02-21 |
2023-08-12 |
rat |
| Scott E Hemby, Wenxue Tang, Emil C Muly, Michael J Kuhar, Leonard Howell, Deborah C Mas. Cocaine-induced alterations in nucleus accumbens ionotropic glutamate receptor subunits in human and non-human primates. Journal of neurochemistry. vol 95. issue 6. 2006-01-20. PMID:16363995. |
the present study was undertaken to examine the extent of altered ionotropic glutamate receptor (iglur) subunit expression in the nac and the putamen in cocaine overdose victims. |
2006-01-20 |
2023-08-12 |
human |
| Bankole A Johnso. Recent advances in the development of treatments for alcohol and cocaine dependence: focus on topiramate and other modulators of GABA or glutamate function. CNS drugs. vol 19. issue 10. 2005-12-07. PMID:16185095. |
recent advances in the development of treatments for alcohol and cocaine dependence: focus on topiramate and other modulators of gaba or glutamate function. |
2005-12-07 |
2023-08-12 |
Not clear |
| Justin M Dunn, Brian R Inderwies, Stephanie C Licata, R Christopher Pierc. Repeated administration of AMPA or a metabotropic glutamate receptor agonist into the rat ventral tegmental area augments the subsequent behavioral hyperactivity induced by cocaine. Psychopharmacology. vol 179. issue 1. 2005-10-24. PMID:15580483. |
repeated administration of ampa or a metabotropic glutamate receptor agonist into the rat ventral tegmental area augments the subsequent behavioral hyperactivity induced by cocaine. |
2005-10-24 |
2023-08-12 |
rat |
| Justin M Dunn, Brian R Inderwies, Stephanie C Licata, R Christopher Pierc. Repeated administration of AMPA or a metabotropic glutamate receptor agonist into the rat ventral tegmental area augments the subsequent behavioral hyperactivity induced by cocaine. Psychopharmacology. vol 179. issue 1. 2005-10-24. PMID:15580483. |
glutamate receptors and their related second messengers in the ventral tegmental area (vta) are known to play critical roles in the initiation of behavioral sensitization to cocaine. |
2005-10-24 |
2023-08-12 |
rat |
| Paul J Kenny, Benjamin Boutrel, Fabrizio Gasparini, George F Koob, Athina Marko. Metabotropic glutamate 5 receptor blockade may attenuate cocaine self-administration by decreasing brain reward function in rats. Psychopharmacology. vol 179. issue 1. 2005-10-24. PMID:15602687. |
metabotropic glutamate 5 receptor blockade may attenuate cocaine self-administration by decreasing brain reward function in rats. |
2005-10-24 |
2023-08-12 |
rat |
| Neil E Paterson, Athina Marko. The metabotropic glutamate receptor 5 antagonist MPEP decreased break points for nicotine, cocaine and food in rats. Psychopharmacology. vol 179. issue 1. 2005-10-24. PMID:15619120. |
the metabotropic glutamate receptor 5 antagonist mpep decreased break points for nicotine, cocaine and food in rats. |
2005-10-24 |
2023-08-12 |
rat |
| K K Szumlinski, K D Lominac, M J Kleschen, E B Oleson, M H Dehoff, M K Schwarz, M K Schwartz, P H Seeburg, P H Seeberg, P F Worley, P W Kaliva. Behavioral and neurochemical phenotyping of Homer1 mutant mice: possible relevance to schizophrenia. Genes, brain, and behavior. vol 4. issue 5. 2005-10-20. PMID:16011574. |
moreover, in homer1-ko mice, cocaine did not stimulate a rise in frontal cortex extracellular glutamate levels, suggesting hypofrontality. |
2005-10-20 |
2023-08-12 |
mouse |
| B L McKee, C K Meshu. Time-dependent changes in extracellular glutamate in the rat dorsolateral striatum following a single cocaine injection. Neuroscience. vol 133. issue 2. 2005-08-30. PMID:15878803. |
time-dependent changes in extracellular glutamate in the rat dorsolateral striatum following a single cocaine injection. |
2005-08-30 |
2023-08-12 |
rat |
| B L McKee, C K Meshu. Time-dependent changes in extracellular glutamate in the rat dorsolateral striatum following a single cocaine injection. Neuroscience. vol 133. issue 2. 2005-08-30. PMID:15878803. |
to date, the effects of acute cocaine on extracellular glutamate and nerve terminal glutamate immunolabeling in the rat dorsolateral striatum have not been reported. |
2005-08-30 |
2023-08-12 |
rat |
| B L McKee, C K Meshu. Time-dependent changes in extracellular glutamate in the rat dorsolateral striatum following a single cocaine injection. Neuroscience. vol 133. issue 2. 2005-08-30. PMID:15878803. |
to investigate cocaine-induced changes in extracellular glutamate, in vivo microdialysis was carried out in the dorsolateral striatum of rats 1-14 days after receiving a single injection of either vehicle or 15 mg/kg cocaine. |
2005-08-30 |
2023-08-12 |
rat |
| B L McKee, C K Meshu. Time-dependent changes in extracellular glutamate in the rat dorsolateral striatum following a single cocaine injection. Neuroscience. vol 133. issue 2. 2005-08-30. PMID:15878803. |
there was an increase in the group injected with cocaine 1 day prior to measuring extracellular glutamate as compared with the control group. |
2005-08-30 |
2023-08-12 |
rat |
| B L McKee, C K Meshu. Time-dependent changes in extracellular glutamate in the rat dorsolateral striatum following a single cocaine injection. Neuroscience. vol 133. issue 2. 2005-08-30. PMID:15878803. |
the group injected with cocaine 3 days prior to the microdialysis session had decreased extracellular glutamate levels. |
2005-08-30 |
2023-08-12 |
rat |
| B L McKee, C K Meshu. Time-dependent changes in extracellular glutamate in the rat dorsolateral striatum following a single cocaine injection. Neuroscience. vol 133. issue 2. 2005-08-30. PMID:15878803. |
furthermore, extracellular glutamate remained attenuated 14 days after acute cocaine treatment. |
2005-08-30 |
2023-08-12 |
rat |
| B L McKee, C K Meshu. Time-dependent changes in extracellular glutamate in the rat dorsolateral striatum following a single cocaine injection. Neuroscience. vol 133. issue 2. 2005-08-30. PMID:15878803. |
the density of nerve terminal glutamate immunolabeling was measured using immunogold electron microscopy in the contralateral striatum of the same rats that had been acutely treated with cocaine or vehicle. |
2005-08-30 |
2023-08-12 |
rat |
| B L McKee, C K Meshu. Time-dependent changes in extracellular glutamate in the rat dorsolateral striatum following a single cocaine injection. Neuroscience. vol 133. issue 2. 2005-08-30. PMID:15878803. |
there were no changes in the density of glutamate immunolabeling within identified nerve terminals making an asymmetrical (excitatory) synaptic contact 1, 2, 3, or 14 days after acute cocaine exposure as compared with the control groups. |
2005-08-30 |
2023-08-12 |
rat |
| B L McKee, C K Meshu. Time-dependent changes in extracellular glutamate in the rat dorsolateral striatum following a single cocaine injection. Neuroscience. vol 133. issue 2. 2005-08-30. PMID:15878803. |
in addition, no changes in glutamate immunolabeling were found in rats that received cocaine 2 h previously or were withdrawn after 1 week of cocaine administration. |
2005-08-30 |
2023-08-12 |
rat |
| B L McKee, C K Meshu. Time-dependent changes in extracellular glutamate in the rat dorsolateral striatum following a single cocaine injection. Neuroscience. vol 133. issue 2. 2005-08-30. PMID:15878803. |
the results demonstrate that a single injection of cocaine produces biphasic, time-dependent changes in extracellular glutamate in the rat dorsolateral striatum. |
2005-08-30 |
2023-08-12 |
rat |