| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chiung-Chun Huang, Che-Ming Yeh, Mei-Ying Wu, Alice Y W Chang, Julie Y H Chan, Samuel H H Chan, Kuei-Sen Hs. Cocaine withdrawal impairs metabotropic glutamate receptor-dependent long-term depression in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 11. 2011-06-15. PMID:21411660. |
using a mouse model of behavioral sensitization, we show that animals withdrawn from repeated cocaine exposure have a selective deficit in the ability to elicit metabotropic glutamate receptor (mglur)-dependent long-term depression (ltd) in the shell of the nac in response to bath application of the group i mglur agonist (s)-3,5-dihydroxyphenylglycine (dhpg). |
2011-06-15 |
2023-08-12 |
mouse |
| Kathryn J Reissner, Joachim D Uys, John H Schwacke, Susanna Comte-Walters, Jennifer L Rutherford-Bethard, Thomas E Dunn, Joe B Blumer, Kevin L Schey, Peter W Kaliva. AKAP signaling in reinstated cocaine seeking revealed by iTRAQ proteomic analysis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 15. 2011-06-13. PMID:21490206. |
reinstatement of cocaine seeking is thought to require upregulated surface expression of ampa glutamate receptors, and the inhibitory akap peptide reduced the psd content of protein kinase a (pka) as well as surface expression of glur1 in nac. |
2011-06-13 |
2023-08-12 |
human |
| Manuel Mameli, Camilla Bellone, Matthew T C Brown, Christian Lüsche. Cocaine inverts rules for synaptic plasticity of glutamate transmission in the ventral tegmental area. Nature neuroscience. vol 14. issue 4. 2011-05-26. PMID:21336270. |
cocaine inverts rules for synaptic plasticity of glutamate transmission in the ventral tegmental area. |
2011-05-26 |
2023-08-12 |
mouse |
| Manuel Mameli, Camilla Bellone, Matthew T C Brown, Christian Lüsche. Cocaine inverts rules for synaptic plasticity of glutamate transmission in the ventral tegmental area. Nature neuroscience. vol 14. issue 4. 2011-05-26. PMID:21336270. |
consequently, a stimulation protocol pairing glutamate release with hyperpolarizing current injections further strengthened synapses after cocaine treatment. |
2011-05-26 |
2023-08-12 |
mouse |
| Vincent Pascoli, Antoine Besnard, Denis Hervé, Christiane Pagès, Nicolas Heck, Jean-Antoine Girault, Jocelyne Caboche, Peter Vanhoutt. Cyclic adenosine monophosphate-independent tyrosine phosphorylation of NR2B mediates cocaine-induced extracellular signal-regulated kinase activation. Biological psychiatry. vol 69. issue 3. 2011-04-28. PMID:21055728. |
in response to cocaine, erk phosphorylation (i.e., activation) is restricted to medium-sized spiny neurons expressing dopamine d1 receptor (d1r) and depends on a concomitant stimulation of d1r and glutamate n-methyl-d-aspartate receptor (nmdar). |
2011-04-28 |
2023-08-12 |
Not clear |
| S M Rawls, F Karaca, I Madhani, V Bhojani, R L Martinez, M Abou-Gharbia, R B Raff. β-lactamase inhibitors display anti-seizure properties in an invertebrate assay. Neuroscience. vol 169. issue 4. 2011-04-18. PMID:20600649. |
glutamate or cocaine administration produced planarian seizure-like activity (psla). |
2011-04-18 |
2023-08-12 |
Not clear |
| Rafal M Kaminski, Juan F Núñez-Taltavull, Bogusława Budziszewska, Władysław Lasoń, Maciej Gasior, Agustin Zapata, Toni S Shippenberg, Jeffrey M Witki. Effects of cocaine-kindling on the expression of NMDA receptors and glutamate levels in mouse brain. Neurochemical research. vol 36. issue 1. 2011-04-18. PMID:20927585. |
in the present study we examined the effects of cocaine seizure kindling on the expression of nmda receptors and levels of extracellular glutamate in mouse brain. |
2011-04-18 |
2023-08-12 |
mouse |
| Rafal M Kaminski, Juan F Núñez-Taltavull, Bogusława Budziszewska, Władysław Lasoń, Maciej Gasior, Agustin Zapata, Toni S Shippenberg, Jeffrey M Witki. Effects of cocaine-kindling on the expression of NMDA receptors and glutamate levels in mouse brain. Neurochemical research. vol 36. issue 1. 2011-04-18. PMID:20927585. |
these data suggest that enhancement of depolarization stimulated glutamate release may be one of the mechanisms underlying the development of increased seizure susceptibility after cocaine kindling. |
2011-04-18 |
2023-08-12 |
mouse |
| Kyung-Ok Cho, Seong Yun Ki. Effects of brain insults and pharmacological manipulations on the adult hippocampal neurogenesis. Archives of pharmacal research. vol 33. issue 10. 2011-03-07. PMID:21052928. |
further, we discuss the stimulatory and inhibitory actions on adult hippocampal neurogenesis by biochemicals and pharmacological agents, including antidepressants, antipsychotics, agonists and antagonists of glutamate and gaba, adrenal corticoids, gonadal hormones, growth factors such as insulin-like growth factor i, erythropoietin, and drugs of abuse, including nicotine, alcohol, opiates, cocaine, methamphetamine, and 3,4-methylenedioxymethamphetamine ("ecstasy"). |
2011-03-07 |
2023-08-12 |
human |
| Khaled Moussawi, Wenhua Zhou, Haowei Shen, Carmela M Reichel, Ronald E See, David B Carr, Peter W Kaliva. Reversing cocaine-induced synaptic potentiation provides enduring protection from relapse. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 1. 2011-02-10. PMID:21173236. |
here we show in rats trained to self-administer cocaine that the enduring cocaine-induced changes in synaptic potentiation and glutamate homeostasis are mechanistically linked through group ii metabotropic glutamate receptor signaling. |
2011-02-10 |
2023-08-12 |
rat |
| Chun-Ting Lee, Jia Chen, Lila T Worden, William J Free. Cocaine causes deficits in radial migration and alters the distribution of glutamate and GABA neurons in the developing rat cerebral cortex. Synapse (New York, N.Y.). vol 65. issue 1. 2011-02-04. PMID:20506319. |
cocaine causes deficits in radial migration and alters the distribution of glutamate and gaba neurons in the developing rat cerebral cortex. |
2011-02-04 |
2023-08-12 |
rat |
| Chun-Ting Lee, Jia Chen, Lila T Worden, William J Free. Cocaine causes deficits in radial migration and alters the distribution of glutamate and GABA neurons in the developing rat cerebral cortex. Synapse (New York, N.Y.). vol 65. issue 1. 2011-02-04. PMID:20506319. |
previously, we found that neural progenitor proliferation in the neocortical ventricular zone (vz) is inhibited by cocaine; here, we examine the changes in cortical neurogenesis and migration of glutamate and gaba neurons induced by prenatal cocaine exposure. |
2011-02-04 |
2023-08-12 |
rat |
| Yue Hao, Rémi Martin-Fardon, Friedbert Weis. Behavioral and functional evidence of metabotropic glutamate receptor 2/3 and metabotropic glutamate receptor 5 dysregulation in cocaine-escalated rats: factor in the transition to dependence. Biological psychiatry. vol 68. issue 3. 2010-11-22. PMID:20416862. |
we examined here whether neuroadaptive dysregulation of metabotropic glutamate receptor function is a factor in escalating cocaine self-administration. |
2010-11-22 |
2023-08-12 |
rat |
| Scott M Rawls, Tavni Patil, Ekaternia Yuvasheva, Robert B Raff. First evidence that drugs of abuse produce behavioral sensitization and cross sensitization in planarians. Behavioural pharmacology. vol 21. issue 4. 2010-11-04. PMID:20512030. |
we tested this hypothesis by determining whether planarians display sensitization and cross sensitization to cocaine and glutamate. |
2010-11-04 |
2023-08-12 |
Not clear |
| Scott M Rawls, Tavni Patil, Ekaternia Yuvasheva, Robert B Raff. First evidence that drugs of abuse produce behavioral sensitization and cross sensitization in planarians. Behavioural pharmacology. vol 21. issue 4. 2010-11-04. PMID:20512030. |
planarians exposed initially to cocaine (or glutamate) on day 1 were challenged with cocaine (or glutamate) after 2 or 6 days of abstinence. |
2010-11-04 |
2023-08-12 |
Not clear |
| Scott M Rawls, Tavni Patil, Ekaternia Yuvasheva, Robert B Raff. First evidence that drugs of abuse produce behavioral sensitization and cross sensitization in planarians. Behavioural pharmacology. vol 21. issue 4. 2010-11-04. PMID:20512030. |
acute cocaine or glutamate produced concentration-related hyperactivity. |
2010-11-04 |
2023-08-12 |
Not clear |
| Scott M Rawls, Tavni Patil, Ekaternia Yuvasheva, Robert B Raff. First evidence that drugs of abuse produce behavioral sensitization and cross sensitization in planarians. Behavioural pharmacology. vol 21. issue 4. 2010-11-04. PMID:20512030. |
cocaine or glutamate challenge after 2 and 6 days of abstinence enhanced the hyperactivity, indicating the substances produced planarian behavioral sensitization. |
2010-11-04 |
2023-08-12 |
Not clear |
| Scott M Rawls, Tavni Patil, Ekaternia Yuvasheva, Robert B Raff. First evidence that drugs of abuse produce behavioral sensitization and cross sensitization in planarians. Behavioural pharmacology. vol 21. issue 4. 2010-11-04. PMID:20512030. |
cross-sensitization experiments showed that cocaine produced greater hyperactivity in planarians earlier exposed to glutamate than in glutamate-naive planarians, and vice versa. |
2010-11-04 |
2023-08-12 |
Not clear |
| Nobuyoshi Suto, Laurel E Ecke, Zhi-Bing You, Roy A Wis. Extracellular fluctuations of dopamine and glutamate in the nucleus accumbens core and shell associated with lever-pressing during cocaine self-administration, extinction, and yoked cocaine administration. Psychopharmacology. vol 211. issue 3. 2010-10-15. PMID:20544343. |
extracellular fluctuations of dopamine and glutamate in the nucleus accumbens core and shell associated with lever-pressing during cocaine self-administration, extinction, and yoked cocaine administration. |
2010-10-15 |
2023-08-12 |
Not clear |
| Irene Brunk, Carles Sanchis-Segura, Christian Blex, Stéphanie Perreau-Lenz, Ainhoa Bilbao, Rainer Spanagel, Gudrun Ahnert-Hilge. Amphetamine regulates NR2B expression in Go2α knockout mice and thereby sustains behavioral sensitization. Journal of neurochemistry. vol 115. issue 1. 2010-10-13. PMID:20649838. |
furthermore, amphetamine but not cocaine treatment maintained the ratio between the glutamate receptor mglur1/5 interacting proteins homer and homer1a in the knockouts thereby sustaining the direct pathway. |
2010-10-13 |
2023-08-12 |
mouse |