| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hu Chen, Hari Mane. Effects of minocycline on cocaine sensitization and phosphorylation of GluR1 receptors in 5-lipoxygenase deficient mice. Neuropharmacology. vol 60. issue 7-8. 2012-01-18. PMID:20868701. |
locomotor sensitization was induced by 4 daily cocaine injections and the phosphorylation status of glur1 glutamate receptors was assayed in brain samples. |
2012-01-18 |
2023-08-12 |
mouse |
| Camilla Bellone, Manuel Mameli, Christian Lüsche. In utero exposure to cocaine delays postnatal synaptic maturation of glutamatergic transmission in the VTA. Nature neuroscience. vol 14. issue 11. 2011-12-21. PMID:21964489. |
when pregnant mice were exposed to cocaine, this glutamate receptor switch was delayed in offspring as a result of a direct effect of cocaine on the fetal dopamine transporter and impaired mglur1 function. |
2011-12-21 |
2023-08-12 |
mouse |
| Richard M Cleva, Megan P Hicks, Justin T Gass, Kelly C Wischerath, Elizabeth T Plasters, John J Widholm, M Foster Oliv. mGluR5 positive allosteric modulation enhances extinction learning following cocaine self-administration. Behavioral neuroscience. vol 125. issue 1. 2011-12-20. PMID:21319882. |
in this study, the authors investigated the effects of the type-5 metabotropic glutamate receptors (mglur5) positive allosteric modulator 3-cyano-n-(1,3-diphenyl-1h-pyrazol-5-yl)benzamide (cdppb) on the extinction of cocaine-seeking behavior in rats with a history of intravenous cocaine self-administration. |
2011-12-20 |
2023-08-12 |
rat |
| James E McCutcheon, Jessica A Loweth, Kerstin A Ford, Michela Marinelli, Marina E Wolf, Kuei Y Tsen. Group I mGluR activation reverses cocaine-induced accumulation of calcium-permeable AMPA receptors in nucleus accumbens synapses via a protein kinase C-dependent mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 41. 2011-12-06. PMID:21994370. |
using patch-clamp recordings from nac slices prepared after extended access cocaine self-administration and >45 d of withdrawal, we found that group i metabotropic glutamate receptor (mglur) stimulation using 3,5-dihydroxyphenylglycine (dhpg; 50 μm) rapidly eliminates the postsynaptic cp-ampar contribution to nac synaptic transmission. |
2011-12-06 |
2023-08-12 |
rat |
| Sara Jane Ward, Bruce A Rasmussen, Gladys Corley, Craig Henry, Jae K Kim, Ellen A Walker, Scott M Rawl. Beta-lactam antibiotic decreases acquisition of and motivation to respond for cocaine, but not sweet food, in C57Bl/6 mice. Behavioural pharmacology. vol 22. issue 4. 2011-11-15. PMID:21543969. |
we tested the hypotheses that the glutamate transporter subtype 1 activator, ceftriaxone, disrupts acquisition of cocaine self-administration, motivation to self-administer cocaine, and conditioned place preference in mice. |
2011-11-15 |
2023-08-12 |
mouse |
| Kun Liu, Jeffery D Stekete. Repeated exposure to cocaine alters medial prefrontal cortex dopamine D₂-like receptor modulation of glutamate and dopamine neurotransmission within the mesocorticolimbic system. Journal of neurochemistry. vol 119. issue 2. 2011-11-15. PMID:21692802. |
repeated exposure to cocaine alters medial prefrontal cortex dopamine d₂-like receptor modulation of glutamate and dopamine neurotransmission within the mesocorticolimbic system. |
2011-11-15 |
2023-08-12 |
rat |
| Raveendra-Panickar Dhanya, Shyama Sidique, Douglas J Sheffler, Hilary Highfield Nickols, Ananda Herath, Li Yang, Russell Dahl, Robert Ardecky, Svetlana Semenova, Athina Markou, P Jeffrey Conn, Nicholas D P Cosfor. Design and synthesis of an orally active metabotropic glutamate receptor subtype-2 (mGluR2) positive allosteric modulator (PAM) that decreases cocaine self-administration in rats. Journal of medicinal chemistry. vol 54. issue 1. 2011-11-09. PMID:21155570. |
design and synthesis of an orally active metabotropic glutamate receptor subtype-2 (mglur2) positive allosteric modulator (pam) that decreases cocaine self-administration in rats. |
2011-11-09 |
2023-08-12 |
rat |
| Jolanta Kotlinska, Marcin Bochensk. Pretreatment with group I metabotropic glutamate receptors antagonists attenuates lethality induced by acute cocaine overdose and expression of sensitization to hyperlocomotor effect of cocaine in mice. Neurotoxicity research. vol 19. issue 1. 2011-11-08. PMID:19936864. |
pretreatment with group i metabotropic glutamate receptors antagonists attenuates lethality induced by acute cocaine overdose and expression of sensitization to hyperlocomotor effect of cocaine in mice. |
2011-11-08 |
2023-08-12 |
mouse |
| Jolanta Kotlinska, Marcin Bochensk. Pretreatment with group I metabotropic glutamate receptors antagonists attenuates lethality induced by acute cocaine overdose and expression of sensitization to hyperlocomotor effect of cocaine in mice. Neurotoxicity research. vol 19. issue 1. 2011-11-08. PMID:19936864. |
the aim of the present study was to test, whether group i metabotropic glutamate receptors (mglurs) antagonists (mglur1 and mglur5) differentially regulate toxic versus behavioral effects of cocaine, both phenomena relevant to the psychopathology of cocaine addiction in humans. |
2011-11-08 |
2023-08-12 |
mouse |
| Marina E Wol. Regulation of AMPA receptor trafficking in the nucleus accumbens by dopamine and cocaine. Neurotoxicity research. vol 18. issue 3-4. 2011-09-15. PMID:20361291. |
we hypothesize that this increases the reactivity of nac neurons to glutamate inputs from cortex and limbic structures, facilitating the ability of these inputs to trigger cocaine seeking and thus contributing to the persistent vulnerability to relapse that characterizes addiction. |
2011-09-15 |
2023-08-12 |
rat |
| T J R Beveridge, H R Smith, M A Nader, L J Porrin. Group II metabotropic glutamate receptors in the striatum of non-human primates: dysregulation following chronic cocaine self-administration. Neuroscience letters. vol 496. issue 1. 2011-08-26. PMID:21458540. |
group ii metabotropic glutamate receptors in the striatum of non-human primates: dysregulation following chronic cocaine self-administration. |
2011-08-26 |
2023-08-12 |
monkey |
| T J R Beveridge, H R Smith, M A Nader, L J Porrin. Group II metabotropic glutamate receptors in the striatum of non-human primates: dysregulation following chronic cocaine self-administration. Neuroscience letters. vol 496. issue 1. 2011-08-26. PMID:21458540. |
a growing body of evidence has demonstrated a role for group ii metabotropic glutamate receptors (mglurs) in the reinforcing effects of cocaine. |
2011-08-26 |
2023-08-12 |
monkey |
| T J R Beveridge, H R Smith, M A Nader, L J Porrin. Group II metabotropic glutamate receptors in the striatum of non-human primates: dysregulation following chronic cocaine self-administration. Neuroscience letters. vol 496. issue 1. 2011-08-26. PMID:21458540. |
cocaine-induced dysregulation of the glutamate system, and its consequent impact on plasticity and synaptic remodeling, will likely be an important consideration in the development of novel pharmacotherapies for cocaine addiction. |
2011-08-26 |
2023-08-12 |
monkey |
| Kwang Ho Choi, Scott Edwards, Danielle L Graham, Erin B Larson, Kimberly N Whisler, Diana Simmons, Allyson K Friedman, Jessica J Walsh, Zia Rahman, Lisa M Monteggia, Amelia J Eisch, Rachael L Neve, Eric J Nestler, Ming-Hu Han, David W Sel. Reinforcement-related regulation of AMPA glutamate receptor subunits in the ventral tegmental area enhances motivation for cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 21. 2011-08-04. PMID:21613507. |
reinforcement-related regulation of ampa glutamate receptor subunits in the ventral tegmental area enhances motivation for cocaine. |
2011-08-04 |
2023-08-12 |
rat |
| Kwang Ho Choi, Scott Edwards, Danielle L Graham, Erin B Larson, Kimberly N Whisler, Diana Simmons, Allyson K Friedman, Jessica J Walsh, Zia Rahman, Lisa M Monteggia, Amelia J Eisch, Rachael L Neve, Eric J Nestler, Ming-Hu Han, David W Sel. Reinforcement-related regulation of AMPA glutamate receptor subunits in the ventral tegmental area enhances motivation for cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 21. 2011-08-04. PMID:21613507. |
here we show that daily intravenous cocaine self-administration, but not passive cocaine administration, induces dynamic upregulation of the ampa glutamate receptor subunits glur1 and glur2 in the ventral tegmental area (vta) of rats. |
2011-08-04 |
2023-08-12 |
rat |
| Joachim D Uys, Kathryn J Reissne. Glutamatergic neuroplasticity in cocaine addiction. Progress in molecular biology and translational science. vol 98. 2011-07-27. PMID:21199777. |
for example, cocaine induces changes in extracellular glutamate concentrations and in synaptic glutamatergic transmission. |
2011-07-27 |
2023-08-12 |
Not clear |
| Joachim D Uys, Kathryn J Reissne. Glutamatergic neuroplasticity in cocaine addiction. Progress in molecular biology and translational science. vol 98. 2011-07-27. PMID:21199777. |
in addition, glutamate receptors are required for the expression of cocaine-related behaviors, and long-term changes have been reported in the expression of proteins at glutamatergic synapses, in glutamate-related redox regulation of neurons, and in glutamatergic synaptic and structural plasticity following chronic exposure to cocaine. |
2011-07-27 |
2023-08-12 |
Not clear |
| Andreas A Argyriou, Panagiotis Karanasios, Alexandra Makridou, Maria Vlachou, Fotini Giannakopoulou, Nicolaos Makri. Cocaine use and abuse triggering sporadic young-onset amyotrophic lateral sclerosis. Neuro-degenerative diseases. vol 8. issue 3. 2011-07-19. PMID:20714119. |
our case supports the view that cocaine use and abuse may trigger a process of motor neuron degeneration by mechanisms implicating alterations in the neurobiology of the excitatory neurotransmitter glutamate and its receptors. |
2011-07-19 |
2023-08-12 |
Not clear |
| Li-Min Mao, Ming-Lei Guo, Dao-Zhong Jin, Eugene E Fibuch, Eun Sang Choe, John Q Wan. Post-translational modification biology of glutamate receptors and drug addiction. Frontiers in neuroanatomy. vol 5. 2011-07-14. PMID:21441996. |
emerging evidence shows that modification processes of striatal glutamate receptors are sensitive to addictive drugs, such as psychostimulants (cocaine and amphetamine). |
2011-07-14 |
2023-08-12 |
Not clear |
| Chiung-Chun Huang, Che-Ming Yeh, Mei-Ying Wu, Alice Y W Chang, Julie Y H Chan, Samuel H H Chan, Kuei-Sen Hs. Cocaine withdrawal impairs metabotropic glutamate receptor-dependent long-term depression in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 11. 2011-06-15. PMID:21411660. |
cocaine withdrawal impairs metabotropic glutamate receptor-dependent long-term depression in the nucleus accumbens. |
2011-06-15 |
2023-08-12 |
mouse |