| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L P Dwoskin, J Peris, R P Yasuda, K Philpott, N R Zahnise. Repeated cocaine administration results in supersensitivity of striatal D-2 dopamine autoreceptors to pergolide. Life sciences. vol 42. issue 3. 1988-02-23. PMID:3275855. |
repeated cocaine administration results in supersensitivity of striatal d-2 dopamine autoreceptors to pergolide. |
1988-02-23 |
2023-08-11 |
rat |
| P D Mitchell, G W Smith, E Wells, P A Wes. Inhibition of Uptake1 by dopexamine hydrochloride in vitro. British journal of pharmacology. vol 92. issue 2. 1987-12-24. PMID:2890392. |
4 dopexamine hydrochloride (3 microm) potentiated the inotropic effect of exogenous noradrenaline in paced atria, thereby resembling cocaine (10 microm) and dopamine (30 microm), both of which are known inhibitors of uptake. |
1987-12-24 |
2023-08-11 |
rabbit |
| P D Mitchell, G W Smith, E Wells, P A Wes. Inhibition of Uptake1 by dopexamine hydrochloride in vitro. British journal of pharmacology. vol 92. issue 2. 1987-12-24. PMID:2890392. |
5 the sodium-dependent uptake of [3h]-noradrenaline into rabbit brain synaptosomes was prevented by dopexamine hydrochloride (ic50 26 nm) and cocaine (ic50 108 nm), as well as by two other catecholamines used in the treatment of heart failure, dopamine (ic50 270 nm) and dobutamine (ic50 380 nm). |
1987-12-24 |
2023-08-11 |
rabbit |
| R S Kelly, R M Wightma. Detection of dopamine overflow and diffusion with voltammetry in slices of rat brain. Brain research. vol 423. issue 1-2. 1987-12-22. PMID:3676822. |
the amount of overflow observed is increased when the tissue is perfused with 10 microm cocaine or nomifensine, both recognized inhibitors of dopamine uptake. |
1987-12-22 |
2023-08-11 |
rat |
| W H Church, J B Justice, L D Byr. Extracellular dopamine in rat striatum following uptake inhibition by cocaine, nomifensine and benztropine. European journal of pharmacology. vol 139. issue 3. 1987-11-27. PMID:3666010. |
extracellular dopamine in rat striatum following uptake inhibition by cocaine, nomifensine and benztropine. |
1987-11-27 |
2023-08-11 |
rat |
| W H Church, J B Justice, L D Byr. Extracellular dopamine in rat striatum following uptake inhibition by cocaine, nomifensine and benztropine. European journal of pharmacology. vol 139. issue 3. 1987-11-27. PMID:3666010. |
analysis of 0.5 microliter of dialysate every 5 min showed dose-dependent elevations in extracellular dopamine following systemic administration of nomifensine (1 and 10 mg/kg), benztropine (5 and 25 mg/kg) and cocaine (3, 10 and 30 mg/kg). |
1987-11-27 |
2023-08-11 |
rat |
| M E Trulson, M J Ulisse. Chronic cocaine administration decreases dopamine synthesis rate and increases [3H] spiroperidol binding in rat brain. Brain research bulletin. vol 19. issue 1. 1987-11-20. PMID:3115498. |
chronic cocaine administration decreases dopamine synthesis rate and increases [3h] spiroperidol binding in rat brain. |
1987-11-20 |
2023-08-11 |
rat |
| M E Trulson, M J Ulisse. Chronic cocaine administration decreases dopamine synthesis rate and increases [3H] spiroperidol binding in rat brain. Brain research bulletin. vol 19. issue 1. 1987-11-20. PMID:3115498. |
these data suggest that cocaine produces long-term, if not permanent, effects on central dopamine synthesis. |
1987-11-20 |
2023-08-11 |
rat |
| A J Giannini, W Billet. Bromocriptine-desipramine protocol in treatment of cocaine addiction. Journal of clinical pharmacology. vol 27. issue 8. 1987-11-04. PMID:3308977. |
the authors hypothesize that these results support a model of dopamine depletion and receptor supersensitivity in cocaine withdrawal. |
1987-11-04 |
2023-08-11 |
Not clear |
| J A Cocores, R K Davies, P S Mueller, M S Gol. Cocaine abuse and adult attention deficit disorder. The Journal of clinical psychiatry. vol 48. issue 9. 1987-10-08. PMID:3624209. |
dopamine depletion is believed to result from chronic cocaine abuse. |
1987-10-08 |
2023-08-11 |
Not clear |
| J A Cocores, R K Davies, P S Mueller, M S Gol. Cocaine abuse and adult attention deficit disorder. The Journal of clinical psychiatry. vol 48. issue 9. 1987-10-08. PMID:3624209. |
in both cases, the dopamine agonist bromocriptine was highly effective for treating add and promoting cocaine abstinence. |
1987-10-08 |
2023-08-11 |
Not clear |
| M C Ritz, R J Lamb, S R Goldberg, M J Kuha. Cocaine receptors on dopamine transporters are related to self-administration of cocaine. Science (New York, N.Y.). vol 237. issue 4819. 1987-10-06. PMID:2820058. |
cocaine receptors on dopamine transporters are related to self-administration of cocaine. |
1987-10-06 |
2023-08-11 |
rat |
| M C Ritz, R J Lamb, S R Goldberg, M J Kuha. Cocaine receptors on dopamine transporters are related to self-administration of cocaine. Science (New York, N.Y.). vol 237. issue 4819. 1987-10-06. PMID:2820058. |
thus, the cocaine receptor related to substance abuse is proposed to be the one associated with dopamine uptake inhibition. |
1987-10-06 |
2023-08-11 |
rat |
| G R Hanson, L A Matsuda, J W Gib. Effects of cocaine on methamphetamine-induced neurochemical changes: characterization of cocaine as a monoamine uptake blocker. The Journal of pharmacology and experimental therapeutics. vol 242. issue 2. 1987-09-23. PMID:2886643. |
thus, we have evaluated cocaine as a blocker of dopamine and 5-hydroxytryptamine uptake processes by determining the in vivo effect of concurrent administrations of cocaine on the neurochemical effects of methamphetamine treatments. |
1987-09-23 |
2023-08-11 |
Not clear |
| G R Hanson, L A Matsuda, J W Gib. Effects of cocaine on methamphetamine-induced neurochemical changes: characterization of cocaine as a monoamine uptake blocker. The Journal of pharmacology and experimental therapeutics. vol 242. issue 2. 1987-09-23. PMID:2886643. |
in contrast to other dopamine uptake blockers, such as amfonelic acid, cocaine did not attenuate the methamphetamine effects on striatal tyrosine hydroxylase activity and the concentrations of dopamine, dihydroxyphenylacetic acid and homovanillic acid. |
1987-09-23 |
2023-08-11 |
Not clear |
| J A Cocores, M D Patel, M S Gold, A C Pottas. Cocaine abuse, attention deficit disorder, and bipolar disorder. The Journal of nervous and mental disease. vol 175. issue 7. 1987-08-11. PMID:3598571. |
cocaine is a potent dopamine agonist that frequently stimulates the central nervous system and is often manifested by increased psychomotor activity, impulsivity, euphoria, and rapid thoughts. |
1987-08-11 |
2023-08-11 |
Not clear |
| C A Dackis, M S Gold, D R Sweeney, J P Byron, R Climk. Single-dose bromocriptine reverses cocaine craving. Psychiatry research. vol 20. issue 4. 1987-07-30. PMID:3602212. |
thirteen hospitalized cocaine addicts complaining of cocaine craving were given a single dose of bromocriptine, a dopamine agonist, in a randomized, double-blind, placebo-controlled study design. |
1987-07-30 |
2023-08-11 |
Not clear |
| C A Dackis, M S Gold, D R Sweeney, J P Byron, R Climk. Single-dose bromocriptine reverses cocaine craving. Psychiatry research. vol 20. issue 4. 1987-07-30. PMID:3602212. |
these data suggest that bromocriptine may be effective as a new, nonaddictive pharmacological treatment for cocaine addicts and support the notion that functional dopamine depletion occurs with chronic cocaine use. |
1987-07-30 |
2023-08-11 |
Not clear |
| C A Dackis, M S Gold, A L Pottas. Central stimulant abuse: neurochemistry and pharmacotherapy. Advances in alcohol & substance abuse. vol 6. issue 2. 1987-07-24. PMID:2886014. |
while cocaine produces euphoria through its stimulatory effect on dopamine neurons, several lines of evidence suggest that dopamine depletion occurs after chronic cocaine abuse. |
1987-07-24 |
2023-08-11 |
Not clear |
| C A Dackis, M S Gold, A L Pottas. Central stimulant abuse: neurochemistry and pharmacotherapy. Advances in alcohol & substance abuse. vol 6. issue 2. 1987-07-24. PMID:2886014. |
the dopamine neurotransmitter system is therefore a natural starting point for understanding the biology of cocaine addiction and selecting suitable adjunctive pharmacological agents. |
1987-07-24 |
2023-08-11 |
Not clear |