| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Missale, L Castelletti, S Govoni, P F Spano, M Trabucchi, I Hanbaue. Dopamine uptake is differentially regulated in rat striatum and nucleus accumbens. Journal of neurochemistry. vol 45. issue 1. 1985-07-17. PMID:3998732. |
in rat striatum dopamine uptake is related to a receptor that is specifically labelled by [3h]cocaine in the presence of na+ and is located on dopaminergic terminals. |
1985-07-17 |
2023-08-11 |
rat |
| C Missale, L Castelletti, S Govoni, P F Spano, M Trabucchi, I Hanbaue. Dopamine uptake is differentially regulated in rat striatum and nucleus accumbens. Journal of neurochemistry. vol 45. issue 1. 1985-07-17. PMID:3998732. |
the dopamine uptake is differentially affected in the two areas by single or repeated injections of cocaine. |
1985-07-17 |
2023-08-11 |
rat |
| C Missale, L Castelletti, S Govoni, P F Spano, M Trabucchi, I Hanbaue. Dopamine uptake is differentially regulated in rat striatum and nucleus accumbens. Journal of neurochemistry. vol 45. issue 1. 1985-07-17. PMID:3998732. |
cocaine inhibits dopamine uptake in slices of corpus striatum. |
1985-07-17 |
2023-08-11 |
rat |
| K Chiba, A J Trevor, N Castagnol. Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes. Biochemical and biophysical research communications. vol 128. issue 3. 1985-07-10. PMID:3873939. |
uptake was na+ dependent and inhibited by ouabain, cocaine and dopamine (ki 0.12 microm). |
1985-07-10 |
2023-08-11 |
mouse |
| A M Galzin, S Z Lange. Inhibition by 5,6-dihydroxy-2-dimethylaminotetralin (M7) of noradrenergic neurotransmission in the rabbit hypothalamus: role of alpha-2 adrenoceptors and of dopamine receptors. The Journal of pharmacology and experimental therapeutics. vol 233. issue 2. 1985-07-02. PMID:2987485. |
in the presence of 10 microm cocaine and in a low ca++ medium (0.65 mm), exposure for 8 min to exogenous dopamine (0.01-1 microm) inhibited, in a concentration-dependent manner, the electrically evoked release of [3h]norepinephrine. |
1985-07-02 |
2023-08-11 |
rabbit |
| R D Russell, J S Striplin. Monoaminergic and local anesthetic components of cocaine's effects on kindled seizure expression. Pharmacology, biochemistry, and behavior. vol 22. issue 3. 1985-05-29. PMID:3991758. |
the second experiment examined the effects of cocaine following the administration of three dose levels of the monoamine antagonists haloperidol, prazosin, yohimbine, propranolol, or metergoline (selected for their ability to block dopamine, alpha-1-norepinephrine, alpha-2-norepinephrine, beta-norepinephrine, and serotonin receptors, respectively). |
1985-05-29 |
2023-08-11 |
rat |
| S P Bagch. Cocaine and phencyclidine. Heterogenous dopaminergic interactions with tetrabenazine. Neuropharmacology. vol 24. issue 1. 1985-05-10. PMID:3982601. |
the present study investigated the actions of cocaine, phencyclidine and amfonelic acid upon the formation and release of dopamine in synaptosomes in the brain of the rat in the presence of tetrabenazine and reserpine. |
1985-05-10 |
2023-08-11 |
rat |
| A D Zharikova, O V Godukhi. [Presynaptic autoregulation of dopamine release]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 71. issue 1. 1985-04-11. PMID:2982672. |
an increase in dopamine concentration in the perfusion medium (addition of exogenous dopamine 10(-7) m, or cocaine, the inhibitor of uptake of biogenous amines, 10(-6) m) leads to a decrease in k+--induced release into perfusate of 3h--dopamine preliminarily injected into neostriatum. |
1985-04-11 |
2023-08-11 |
rat |
| B Scatton, A Dubois, M L Dubocovich, N R Zahniser, D Fag. Quantitative autoradiography of 3H-nomifensine binding sites in rat brain. Life sciences. vol 36. issue 9. 1985-04-02. PMID:3974411. |
the dopamine uptake inhibitors benztropine, nomifensine, cocaine, bupropion and amfonelic acid were the most potent competitors of 3h-nomifensine binding to striatal sections. |
1985-04-02 |
2023-08-11 |
rat |
| P Baud, S Arbilla, S Z Lange. Inhibition of the electrically evoked release of [3H]acetylcholine in rat striatal slices: an experimental model for drugs that enhance dopaminergic neurotransmission. Journal of neurochemistry. vol 44. issue 2. 1985-02-21. PMID:2981280. |
similar effects can be obtained if the neuronal uptake of dopamine is inhibited by cocaine or nomifensine. |
1985-02-21 |
2023-08-11 |
rat |
| R A Wis. Neural mechanisms of the reinforcing action of cocaine. NIDA research monograph. vol 50. 1985-01-31. PMID:6440023. |
cocaine prolongs the activity of dopamine in the synapse by blocking the dopamine reuptake mechanism (which usually inactivates the transmitter by removing it from the proximity of its synaptic targets). |
1985-01-31 |
2023-08-12 |
human |
| H O Pettit, A Ettenberg, F E Bloom, G F Koo. Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats. Psychopharmacology. vol 84. issue 2. 1985-01-18. PMID:6438676. |
destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats. |
1985-01-18 |
2023-08-12 |
rat |
| H O Pettit, A Ettenberg, F E Bloom, G F Koo. Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats. Psychopharmacology. vol 84. issue 2. 1985-01-18. PMID:6438676. |
the hypothesis that separate neural systems mediate the reinforcing properties of opioid and psychomotor stimulant drugs was tested by examining the role of mesolimbic dopamine (da) neurons in maintaining intravenous heroin and cocaine self-administration. |
1985-01-18 |
2023-08-12 |
rat |
| b' J Cortijo, J Esplugues, E J Morcillo, M Perpi\\xc3\\xb1\\xc3\\xa. Pharmacological analysis of the responsiveness of guinea-pig lung parenchymal strip to dopamine. British journal of pharmacology. vol 83. issue 1. 1984-11-28. PMID:6487886.' |
cocaine significantly increased the pd2 value of dopamine in the presence of propranolol. |
1984-11-28 |
2023-08-12 |
Not clear |
| H Sershen, M E Reith, A Hashim, A Lajth. Reduction of dopamine uptake and cocaine binding in mouse striatum by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. European journal of pharmacology. vol 102. issue 1. 1984-11-13. PMID:6332738. |
reduction of dopamine uptake and cocaine binding in mouse striatum by n-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. |
1984-11-13 |
2023-08-12 |
mouse |
| H Sershen, M E Reith, A Hashim, A Lajth. Reduction of dopamine uptake and cocaine binding in mouse striatum by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. European journal of pharmacology. vol 102. issue 1. 1984-11-13. PMID:6332738. |
administration of n-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (nmptp) (daily injections of 8 mg/kg for 5 days via tail vein) reduced [3h]dopamine uptake in striatal synaptosomes by 63% and reduced [3h]cocaine binding to striatal membranes by 61%. |
1984-11-13 |
2023-08-12 |
mouse |
| J B Becker, E Castañeda, T E Robinson, M E Bee. A simple in vitro technique to measure the release of endogenous dopamine and dihydroxyphenylacetic acid from striatal tissue using high performance liquid chromatography with electrochemical detection. Journal of neuroscience methods. vol 11. issue 1. 1984-10-11. PMID:6471905. |
to characterize the system, the dynamics of endogenous dopamine and dihydroxyphenylacetic acid release from striatal tissue were studied before and after exposure to potassium, amphetamine or cocaine. |
1984-10-11 |
2023-08-12 |
Not clear |
| R A Lefebvre, J L Willems, M G Bogaer. Inhibitory effect of dopamine on canine gastric fundus. Naunyn-Schmiedeberg's archives of pharmacology. vol 326. issue 1. 1984-10-03. PMID:6147760. |
the inhibition of the electrically induced contractions by dopamine 1 x 10(-4) m was not influenced by the presence of cocaine 3 x 10(-5) m or hydrocortisone 3 x 10(-5) m. the alpha 1- and alpha 2-adrenoceptor antagonist phentolamine and the alpha 2-adrenoceptor antagonist rauwolscine markedly antagonized the inhibitory effect of dopamine on the response to electrical stimulation at 0.5 hz. |
1984-10-03 |
2023-08-12 |
dog |
| R A Lefebvre, J L Willems, M G Bogaer. Inhibitory effect of dopamine on canine gastric fundus. Naunyn-Schmiedeberg's archives of pharmacology. vol 326. issue 1. 1984-10-03. PMID:6147760. |
these results indicate that the inhibitory effect of dopamine in the dog gastric fundus is mainly mediated by an interaction with alpha 2-adrenoceptors on the intramural cholinergic neurons; this effect is largely direct since it was not influenced by cocaine. |
1984-10-03 |
2023-08-12 |
dog |
| K Kashiwabar. [A long-term qualitative behavioral change following chronic methamphetamine administration in Japanese monkeys (Macaca fuscata)]. Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology. vol 3. issue 3. 1984-09-17. PMID:6331689. |
the results obtained were: 1) daily administration of map (1 mg/kg) for 12 weeks resulted in a progressive qualitative alteration of behavior content including increased inhibition and staring, 2) such abnormal behavior was augmented during the chronic treatment and was reappeared by a test dose (0.2 mg/kg) of map after 2 or 4 weeks of abstinence, 3) a progressive increase in behavioral stereotypy was not observed during the chronic treatment, 4) challenge with test doses of various agents showed positive cross sensitization to cocaine, whereas saline and dopamine agonists such as apomorphine and l-dopa failed to reproduce the same abnormal behavior as map-induced one, and 5) behavioral responses to dopamine agonists was changed while negative cross sensitization to 5-htp was found following the chronic map treatment. |
1984-09-17 |
2023-08-12 |
monkey |