| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C A Dackis, M S Gol. Pharmacological approaches to cocaine addiction. Journal of substance abuse treatment. vol 2. issue 3. 1986-04-15. PMID:3912517. |
the involvement of central dopamine (da) neurons in the rewarding action of cocaine is well established. |
1986-04-15 |
2023-08-11 |
Not clear |
| T P Harty, M Davi. Cocaine: effects on acoustic startle and startle elicited electrically from the cochlear nucleus. Psychopharmacology. vol 87. issue 4. 1986-02-17. PMID:3001807. |
these results suggest that cocaine increases startle by acting on sensory rather than final motor systems and are discussed in relation to the putative effect of cocaine on dopamine neurotransmission and the involvement of dopamine in sensorimotor reactivity. |
1986-02-17 |
2023-08-11 |
Not clear |
| L Brown, B Lorenz, E Erdman. The inotropic effects of dopamine and its precursor levodopa on isolated human ventricular myocardium. Klinische Wochenschrift. vol 63. issue 21. 1986-02-17. PMID:4079278. |
this inotropic effect was reduced by the beta 1-selective antagonist, 1-practolol (1 x 10(-6) m); the beta 2-selective antagonist, ici 118,551 hcl (1 x 10(-6) m); the dopamine antagonist, haloperidol (3 x 10(-6) m); the neuronal uptake inhibitor, cocaine (3 x 10(-5) m), but not by the alpha 1-antagonist, prazosin (1 x 10(-7) m). |
1986-02-17 |
2023-08-11 |
human |
| A M Snoddy, R E Tesse. Prazosin: effect on psychomotor-stimulant cues and locomotor activity in mice. European journal of pharmacology. vol 116. issue 3. 1986-02-05. PMID:3878298. |
in addition, prazosin, at a dose that did not affect either saline-associated locomotor behavior in mice or the locomotor-activity increase produced by the dopamine uptake inhibitor, bupropion, also antagonized the locomotor stimulation produced by amphetamine and cocaine. |
1986-02-05 |
2023-08-11 |
mouse |
| M E Reith, H Sershen, A Lajth. Binding sites for [3H]cocaine in mouse striatum and cerebral cortex have different dissociation kinetics. Journal of neurochemistry. vol 46. issue 1. 1986-01-21. PMID:3940290. |
on the basis of previous pharmacological characterization of [3h]cocaine binding, we propose that the slowly dissociating component represents the sites associated with 5-hydroxytryptamine (serotonin) uptake, and the rapidly dissociating component the 3,4-dihydroxyphenylethylamine (dopamine)-related sites. |
1986-01-21 |
2023-08-11 |
mouse |
| C A Dackis, M S Gol. New concepts in cocaine addiction: the dopamine depletion hypothesis. Neuroscience and biobehavioral reviews. vol 9. issue 3. 1986-01-02. PMID:2999657. |
new concepts in cocaine addiction: the dopamine depletion hypothesis. |
1986-01-02 |
2023-08-11 |
Not clear |
| C A Dackis, M S Gold, R K Davies, D R Sweene. Bromocriptine treatment for cocaine abuse: the dopamine depletion hypothesis. International journal of psychiatry in medicine. vol 15. issue 2. 1985-12-09. PMID:3902694. |
bromocriptine treatment for cocaine abuse: the dopamine depletion hypothesis. |
1985-12-09 |
2023-08-11 |
Not clear |
| C A Dackis, M S Gold, R K Davies, D R Sweene. Bromocriptine treatment for cocaine abuse: the dopamine depletion hypothesis. International journal of psychiatry in medicine. vol 15. issue 2. 1985-12-09. PMID:3902694. |
the authors review the evidence that cocaine exerts its rewarding effects through the acute activation of dopamine (da) pathways in the brain. |
1985-12-09 |
2023-08-11 |
Not clear |
| N I Maĭsov, E M Gankina, T A Voronin. [Characteristics of the effect of psychotropic preparations on the synaptosomal uptake of monoamines]. Farmakologiia i toksikologiia. vol 48. issue 4. 1985-11-08. PMID:4043363. |
the psychostimulants amphetamine and cocaine (50 microm) powerfully suppressed noradrenaline, dopamine and serotonin transport without influencing gaba uptake. |
1985-11-08 |
2023-08-11 |
rat |
| R A Mayer, M F Jarvis, G C Wagne. Cocaine blocks the dopamine depletion induced by MPTP. Research communications in chemical pathology and pharmacology. vol 49. issue 1. 1985-10-02. PMID:3875884. |
cocaine blocks the dopamine depletion induced by mptp. |
1985-10-02 |
2023-08-11 |
mouse |
| R A Mayer, M F Jarvis, G C Wagne. Cocaine blocks the dopamine depletion induced by MPTP. Research communications in chemical pathology and pharmacology. vol 49. issue 1. 1985-10-02. PMID:3875884. |
the concomitant administration of a dopamine uptake blocker, cocaine, protected the mice from this mptp-induced dopamine depletion. |
1985-10-02 |
2023-08-11 |
mouse |
| M Davi. Cocaine: excitatory effects on sensorimotor reactivity measured with acoustic startle. Psychopharmacology. vol 86. issue 1-2. 1985-09-25. PMID:3927365. |
the data indicate that cocaine increases startle by acting through reserpine-sensitive pools of dopamine and provide further support for the conclusion that acoustic startle is enhanced by activation of dopamine receptors. |
1985-09-25 |
2023-08-11 |
rat |
| H Schoemaker, C Pimoule, S Arbilla, B Scatton, F Javoy-Agid, S Z Lange. Sodium dependent [3H]cocaine binding associated with dopamine uptake sites in the rat striatum and human putamen decrease after dopaminergic denervation and in Parkinsons disease. Naunyn-Schmiedeberg's archives of pharmacology. vol 329. issue 3. 1985-09-19. PMID:3927176. |
sodium dependent [3h]cocaine binding associated with dopamine uptake sites in the rat striatum and human putamen decrease after dopaminergic denervation and in parkinsons disease. |
1985-09-19 |
2023-08-11 |
human |
| H Schoemaker, C Pimoule, S Arbilla, B Scatton, F Javoy-Agid, S Z Lange. Sodium dependent [3H]cocaine binding associated with dopamine uptake sites in the rat striatum and human putamen decrease after dopaminergic denervation and in Parkinsons disease. Naunyn-Schmiedeberg's archives of pharmacology. vol 329. issue 3. 1985-09-19. PMID:3927176. |
the binding of radiolabelled cocaine, an inhibitor of dopamine uptake, to the post-mortem human putamen was studied and compared to that in the rat striatum. |
1985-09-19 |
2023-08-11 |
human |
| H Schoemaker, C Pimoule, S Arbilla, B Scatton, F Javoy-Agid, S Z Lange. Sodium dependent [3H]cocaine binding associated with dopamine uptake sites in the rat striatum and human putamen decrease after dopaminergic denervation and in Parkinsons disease. Naunyn-Schmiedeberg's archives of pharmacology. vol 329. issue 3. 1985-09-19. PMID:3927176. |
a pharmacological characterisation of high affinity [3h]cocaine binding to rat striatal membranes clearly indicates an association with the neuronal dopamine transporter. |
1985-09-19 |
2023-08-11 |
human |
| H Schoemaker, C Pimoule, S Arbilla, B Scatton, F Javoy-Agid, S Z Lange. Sodium dependent [3H]cocaine binding associated with dopamine uptake sites in the rat striatum and human putamen decrease after dopaminergic denervation and in Parkinsons disease. Naunyn-Schmiedeberg's archives of pharmacology. vol 329. issue 3. 1985-09-19. PMID:3927176. |
the ic50 values of 8 selected drugs for inhibition of [3h]cocaine binding in the rat striatum were highly significantly correlated with their potency to inhibit [3h]dopamine uptake into slices of the rat striatum. |
1985-09-19 |
2023-08-11 |
human |
| H Schoemaker, C Pimoule, S Arbilla, B Scatton, F Javoy-Agid, S Z Lange. Sodium dependent [3H]cocaine binding associated with dopamine uptake sites in the rat striatum and human putamen decrease after dopaminergic denervation and in Parkinsons disease. Naunyn-Schmiedeberg's archives of pharmacology. vol 329. issue 3. 1985-09-19. PMID:3927176. |
drugs with dopamine releasing activity were more potent at inhibiting [3h]dopamine uptake than at competing for the high affinity site of [3h]cocaine binding. |
1985-09-19 |
2023-08-11 |
human |
| H Schoemaker, C Pimoule, S Arbilla, B Scatton, F Javoy-Agid, S Z Lange. Sodium dependent [3H]cocaine binding associated with dopamine uptake sites in the rat striatum and human putamen decrease after dopaminergic denervation and in Parkinsons disease. Naunyn-Schmiedeberg's archives of pharmacology. vol 329. issue 3. 1985-09-19. PMID:3927176. |
further evidence in support of an association of [3h]cocaine binding in the rat striatum with the dopamine transporter was obtained from lesion studies. |
1985-09-19 |
2023-08-11 |
human |
| T Hunt, L Switzman, Z Ami. Involvement of dopamine in the aversive stimulus properties of cocaine in rats. Pharmacology, biochemistry, and behavior. vol 22. issue 6. 1985-09-16. PMID:2991950. |
involvement of dopamine in the aversive stimulus properties of cocaine in rats. |
1985-09-16 |
2023-08-11 |
rat |
| M Vasse, P Protais, J Costentin, J C Schwart. Unexpected potentiation by discriminant benzamide derivatives of stereotyped behaviours elicited by dopamine agonists in mice. Naunyn-Schmiedeberg's archives of pharmacology. vol 329. issue 2. 1985-08-13. PMID:4040215. |
amisulpride also allows the emergence of the two stereotyped behaviours in mice receiving other dopamine agonists in subthreshold dosages (dipropyl 5,6-adtn, dexamphetamine or cocaine). |
1985-08-13 |
2023-08-11 |
mouse |