| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C A Dackis, M S Gold, A L Pottas. Central stimulant abuse: neurochemistry and pharmacotherapy. Advances in alcohol & substance abuse. vol 6. issue 2. 1987-07-24. PMID:2886014. |
furthermore, the dopamine depletion hypothesis implies that cocaine is "physically" addictive and provides a biological framework for understanding this disease and refining present therapeutic approaches. |
1987-07-24 |
2023-08-11 |
Not clear |
| D F Dougan, P Duffield, D N Wad. Modulation of dopamine receptors in the Tapes clam by dextroamphetamine and phenylethanolamine. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 86. issue 2. 1987-06-08. PMID:2882924. |
dextroamphetamine and phenylethanolamine but not cocaine and benztropine have the ability to unmask inhibitory responses to both dopamine and serotonin in the ventricle. |
1987-06-08 |
2023-08-11 |
Not clear |
| N E Goeders, M J Kuha. Chronic cocaine administration induces opposite changes in dopamine receptors in the striatum and nucleus accumbens. Alcohol and drug research. vol 7. issue 4. 1987-05-21. PMID:2950865. |
chronic cocaine administration induces opposite changes in dopamine receptors in the striatum and nucleus accumbens. |
1987-05-21 |
2023-08-11 |
rat |
| D C Roberts, J C Dalton, G J Vicker. Increased self-administration of cocaine following haloperidol: effect of ovariectomy, estrogen replacement, and estrous cycle. Pharmacology, biochemistry, and behavior. vol 26. issue 1. 1987-05-11. PMID:3562496. |
rats which have been trained to self-administer cocaine intravenously show a dose-dependent increase in drug intake when pretreated with dopamine antagonists. |
1987-05-11 |
2023-08-11 |
human |
| D K Banerjee, R A Lutz, M A Levine, D Rodbard, H B Pollar. Uptake of norepinephrine and related catecholamines by cultured chromaffin cells: characterization of cocaine-sensitive and -insensitive plasma membrane transport sites. Proceedings of the National Academy of Sciences of the United States of America. vol 84. issue 7. 1987-05-04. PMID:3031648. |
norepinephrine and its closely related analogues, dopamine and epinephrine, are transported into chromaffin cells in culture by two distinct types of sites on the plasma membrane: one is sensitive to cocaine while the other is not. |
1987-05-04 |
2023-08-11 |
Not clear |
| M A Morency, R J Stewart, R J Beninge. Circling behavior following unilateral microinjections of cocaine into the medial prefrontal cortex: dopaminergic or local anesthetic effect? The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 7. issue 3. 1987-04-29. PMID:3559712. |
cocaine was found to produce dose-dependent contraversive circling, an effect previously seen with the dopamine (da) agonists ly 14 1865 and (+)-amphetamine, suggesting a unilateral stimulant effect. |
1987-04-29 |
2023-08-11 |
rat |
| A H Tang, S R Frankli. Discriminative stimulus effects of a low dose of apomorphine in the rat. Psychopharmacology. vol 91. issue 1. 1987-04-06. PMID:3103160. |
the indirect-acting dopamine agonists, (+)amphetamine, cocaine, and methylphenidate produced predominantly saline-appropriate lever responses. |
1987-04-06 |
2023-08-11 |
rat |
| Anand L Misra, Ronald B Pontani, Narasimham L Vadlaman. Stereospecific potentiation of opiate analgesia by cocaine: predominant role of noradrenaline. Pain. vol 28. issue 1. 1987-03-30. PMID:3822492. |
pseudo-cocaine (dextro-cocaine), which is several-fold less potent than cocaine as an inhibitor of noradrenaline and dopamine reuptake in the cns, had no significant effect on opiate analgesia. |
1987-03-30 |
2023-08-11 |
rat |
| F S Tennant, A A Sagheria. Double-blind comparison of amantadine and bromocriptine for ambulatory withdrawal from cocaine dependence. Archives of internal medicine. vol 147. issue 1. 1987-01-28. PMID:3541819. |
amantadine appears to primarily exert its therapeutic influence by releasing dopamine and norepinephrine from neuronal storage sites that are depleted by chronic cocaine dependence, and bromocriptine acts as a dopamine agonist and stimulates dopamine receptors. |
1987-01-28 |
2023-08-11 |
Not clear |
| F H Gawi. Neuroleptic reduction of cocaine-induced paranoia but not euphoria? Psychopharmacology. vol 90. issue 1. 1986-11-12. PMID:2876452. |
four cocaine abusers with histories of stimulant-induced paranoid psychoses reported selective reduction in psychotic symptoms but not euphoria when treated with dopamine blockers. |
1986-11-12 |
2023-08-11 |
Not clear |
| H M Barros, S Braz, J R Leit. Effect of carbamazepine on dopamine release and reuptake in rat striatal slices. Epilepsia. vol 27. issue 5. 1986-11-07. PMID:3757939. |
it was observed that carbamazepine blocked 20% of the reuptake of [3h]dopamine, while cocaine blocked 82% of the reuptake, compared with control. |
1986-11-07 |
2023-08-11 |
rat |
| N E Goeders, J E Smit. Reinforcing properties of cocaine in the medical prefrontal cortex: primary action on presynaptic dopaminergic terminals. Pharmacology, biochemistry, and behavior. vol 25. issue 1. 1986-10-16. PMID:3018792. |
lever-pressing could be reinstated by substituting dopamine (300 pmol) but not serotonin for cocaine. |
1986-10-16 |
2023-08-11 |
rat |
| R A Mayer, M V Kindt, R E Heikkil. Prevention of the nigrostriatal toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by inhibitors of 3,4-dihydroxyphenylethylamine transport. Journal of neurochemistry. vol 47. issue 4. 1986-10-15. PMID:3489072. |
the 3,4-dihydroxyphenylethylamine (da, dopamine) uptake inhibitors gbr 13,069, amfonelic acid, win-35,065-2, win-35,428, nomifensine, mazindol, cocaine, mcn-5908, mcn-5847, and mcn-5292 were effective in preventing [3h]da and [3h]1-methyl-4-phenylpyridinium (mpp+) uptake in rat and mouse neostriatal tissue slices. |
1986-10-15 |
2023-08-11 |
mouse |
| B K Lam, C T Stier, N C Wynn, H D Itskovit. Dopamine and L-dopa potentiation of pressor responses to norepinephrine in isolated perfused rat kidneys. Journal of cardiovascular pharmacology. vol 8. issue 3. 1986-07-28. PMID:2425172. |
infusions of cocaine (15 micrograms/min) enhanced the renal pressor effects of ne but not pe in similar fashion to l-dopa and dopamine. |
1986-07-28 |
2023-08-11 |
rat |
| M E Reith, S S Kim, A Lajth. Structural requirements for cocaine congeners to interact with [3H]batrachotoxinin A 20-alpha-benzoate binding sites on sodium channels in mouse brain synaptosomes. The Journal of biological chemistry. vol 261. issue 16. 1986-07-02. PMID:2423518. |
the present results do not support a relationship between the capability of cocaine congeners in blocking sodium flux and in inhibiting uptake of dopamine into striatal synaptosomes. |
1986-07-02 |
2023-08-11 |
mouse |
| W L Woolverto. Effects of a D1 and a D2 dopamine antagonist on the self-administration of cocaine and piribedil by rhesus monkeys. Pharmacology, biochemistry, and behavior. vol 24. issue 3. 1986-06-17. PMID:2871561. |
effects of a d1 and a d2 dopamine antagonist on the self-administration of cocaine and piribedil by rhesus monkeys. |
1986-06-17 |
2023-08-11 |
monkey |
| W L Woolverto. Effects of a D1 and a D2 dopamine antagonist on the self-administration of cocaine and piribedil by rhesus monkeys. Pharmacology, biochemistry, and behavior. vol 24. issue 3. 1986-06-17. PMID:2871561. |
rhesus monkeys were surgically prepared with chronic intravenous catheters and allowed to self-administer the indirect dopamine (da) agonist cocaine (0.03 or 0.1 mg/kg/inj) or the direct d2 agonist piribedil (0.1 or 0.2 mg/kg/inj) on a fixed-ratio 10 schedule of drug delivery during daily 2 hour experimental sessions. |
1986-06-17 |
2023-08-11 |
monkey |
| A Lucchelli, C Boselli, M C Chiari, E Gran. Analysis of the relaxing effect of dopamine on the isolated rat jejunum. Archives internationales de pharmacodynamie et de therapie. vol 279. issue 2. 1986-05-22. PMID:3963938. |
the relaxing effect of dopamine does not show the tachyphylaxis phenomenon, is present in preparations from rats pretreated with reserpine and is not influenced by cocaine. |
1986-05-22 |
2023-08-11 |
rat |
| M E Reith, B E Meisler, H Sershen, A Lajth. Structural requirements for cocaine congeners to interact with dopamine and serotonin uptake sites in mouse brain and to induce stereotyped behavior. Biochemical pharmacology. vol 35. issue 7. 1986-05-09. PMID:3964292. |
structural requirements for cocaine congeners to interact with dopamine and serotonin uptake sites in mouse brain and to induce stereotyped behavior. |
1986-05-09 |
2023-08-11 |
mouse |
| M E Reith, B E Meisler, H Sershen, A Lajth. Structural requirements for cocaine congeners to interact with dopamine and serotonin uptake sites in mouse brain and to induce stereotyped behavior. Biochemical pharmacology. vol 35. issue 7. 1986-05-09. PMID:3964292. |
we report here saturation analysis of [3h]cocaine binding in various mouse brain regions, and the necessary structure-activity relationships for cocaine congeners to inhibit na+-dependent [3h]cocaine binding and [3h]dopamine uptake in the mouse striatum, and to inhibit [3h]cocaine binding that cannot be stimulated by na+ and [3h]serotonin uptake in the mouse cerebral cortex. |
1986-05-09 |
2023-08-11 |
mouse |