| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T R Kosten, H D Klebe. Rapid death during cocaine abuse: a variant of the neuroleptic malignant syndrome? The American journal of drug and alcohol abuse. vol 14. issue 3. 1988-11-30. PMID:3055940. |
treatment implications are that dopamine antagonists, which are usually prescribed for cocaine overdose, may be contraindicated and instead, dopamine agonists may reverse this rapidly fatal syndrome. |
1988-11-30 |
2023-08-11 |
Not clear |
| M G Lacey, N B Mercuri, R A Nort. On the potassium conductance increase activated by GABAB and dopamine D2 receptors in rat substantia nigra neurones. The Journal of physiology. vol 401. 1988-10-31. PMID:2459376. |
the effect of dopamine was enhanced by cocaine (10 microm) and antagonized by (-)-sulpiride (0.1-1 microm), whereas the actions of baclofen were unaffected by cocaine or (-)-sulpiride. |
1988-10-31 |
2023-08-11 |
rat |
| Y L Hurd, J Kehr, U Ungersted. In vivo microdialysis as a technique to monitor drug transport: correlation of extracellular cocaine levels and dopamine overflow in the rat brain. Journal of neurochemistry. vol 51. issue 4. 1988-10-19. PMID:3418351. |
in vivo microdialysis as a technique to monitor drug transport: correlation of extracellular cocaine levels and dopamine overflow in the rat brain. |
1988-10-19 |
2023-08-11 |
rat |
| Y L Hurd, J Kehr, U Ungersted. In vivo microdialysis as a technique to monitor drug transport: correlation of extracellular cocaine levels and dopamine overflow in the rat brain. Journal of neurochemistry. vol 51. issue 4. 1988-10-19. PMID:3418351. |
in a separate group of animals, the influence of cocaine on extracellular dopamine concentrations in the anteromedial caudate-putamen was also assessed. |
1988-10-19 |
2023-08-11 |
rat |
| Y L Hurd, J Kehr, U Ungersted. In vivo microdialysis as a technique to monitor drug transport: correlation of extracellular cocaine levels and dopamine overflow in the rat brain. Journal of neurochemistry. vol 51. issue 4. 1988-10-19. PMID:3418351. |
in addition, extracellular dopamine levels measured in the anteromedial caudate-putamen following cocaine infusions closely mirrored those of cocaine itself. |
1988-10-19 |
2023-08-11 |
rat |
| M S Kleven, E W Anthony, L I Goldberg, W L Woolverto. Blockade of the discriminative stimulus effects of cocaine in rhesus monkeys with the D1 dopamine antagonist SCH 23390. Psychopharmacology. vol 95. issue 3. 1988-10-11. PMID:2901130. |
blockade of the discriminative stimulus effects of cocaine in rhesus monkeys with the d1 dopamine antagonist sch 23390. |
1988-10-11 |
2023-08-11 |
human |
| M S Kleven, E W Anthony, L I Goldberg, W L Woolverto. Blockade of the discriminative stimulus effects of cocaine in rhesus monkeys with the D1 dopamine antagonist SCH 23390. Psychopharmacology. vol 95. issue 3. 1988-10-11. PMID:2901130. |
to investigate the role of d1 dopamine receptors in the discriminative stimulus effects of cocaine, two rhesus monkeys were trained in a two-lever, food-reinforced, drug discrimination paradigm to discriminate cocaine (0.2 mg/kg, im) from saline. |
1988-10-11 |
2023-08-11 |
human |
| D O Calligaro, M E Eldefraw. High affinity stereospecific binding of [3H] cocaine in striatum and its relationship to the dopamine transporter. Membrane biochemistry. vol 7. issue 2. 1988-09-16. PMID:3454391. |
high affinity stereospecific binding of [3h] cocaine in striatum and its relationship to the dopamine transporter. |
1988-09-16 |
2023-08-11 |
rat |
| D O Calligaro, M E Eldefraw. High affinity stereospecific binding of [3H] cocaine in striatum and its relationship to the dopamine transporter. Membrane biochemistry. vol 7. issue 2. 1988-09-16. PMID:3454391. |
this binding is displaced by cocaine analogues with the same rank order as their inhibition of [3h]dopamine ([3h]da) uptake into striatal synaptosomes (r = 0.99), paralleling the order of their central stimulant activity. |
1988-09-16 |
2023-08-11 |
rat |
| S D Glick, P A Hinds, J L Bair. Two kinds of nigrostriatal asymmetry: relationship to dopaminergic drug sensitivity and 6-hydroxydopamine lesion effects in Long-Evans rats. Brain research. vol 450. issue 1-2. 1988-09-15. PMID:3135915. |
the present study replicated these findings in another strain of rats and showed further that the two populations could be distinguished behaviorally by their relative responses to indirectly acting (d-amphetamine, cocaine) and directly acting (apomorphine, pergolide) dopamine agonists. |
1988-09-15 |
2023-08-11 |
rat |
| J Mendelson, S Teoh, U Lange, N Mello, R Weiss, A Skupn. Hyperprolactinemia during cocaine withdrawal. NIDA research monograph. vol 81. 1988-09-15. PMID:3136392. |
since cocaine blocks dopamine reuptake and prolactin secretion is regulated, in part, by dopaminergic inhibitory mechanisms, cocaine withdrawal may induce rebound supersensitivity of prolactin secretion. |
1988-09-15 |
2023-08-11 |
Not clear |
| A B Schwartz, W Boyle, D Janzen, R T Jone. Acute effects of cocaine on catecholamines and cardiac electrophysiology in the conscious dog. The Canadian journal of cardiology. vol 4. issue 4. 1988-09-01. PMID:3395916. |
plasma noradrenaline, adrenaline and dopamine increased and remained at two to three times control levels throughout the study although plasma cocaine levels declined. |
1988-09-01 |
2023-08-11 |
dog |
| G Di Chiara, A Imperat. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proceedings of the National Academy of Sciences of the United States of America. vol 85. issue 14. 1988-08-24. PMID:2899326. |
drugs abused by humans (e.g., opiates, ethanol, nicotine, amphetamine, and cocaine) increased extracellular dopamine concentrations in both areas, but especially in the accumbens, and elicited hypermotility at low doses. |
1988-08-24 |
2023-08-11 |
rat |
| D R Kapusta, N W Robi. Effects of cocaine and nomifensine on canine renal venous norepinephrine and dopamine content during electrical stimulation of the renal nerves. Journal of cardiovascular pharmacology. vol 11. issue 5. 1988-08-23. PMID:2455836. |
effects of cocaine and nomifensine on canine renal venous norepinephrine and dopamine content during electrical stimulation of the renal nerves. |
1988-08-23 |
2023-08-11 |
Not clear |
| D R Kapusta, N W Robi. Effects of cocaine and nomifensine on canine renal venous norepinephrine and dopamine content during electrical stimulation of the renal nerves. Journal of cardiovascular pharmacology. vol 11. issue 5. 1988-08-23. PMID:2455836. |
thus, to investigate this possibility, we examined whether electrical stimulation of the renal nerves evokes an overflow of dopamine into renal venous blood that could be augmented by cocaine or nomifensine, two inhibitors of presynaptic uptake. |
1988-08-23 |
2023-08-11 |
Not clear |
| D R Kapusta, N W Robi. Effects of cocaine and nomifensine on canine renal venous norepinephrine and dopamine content during electrical stimulation of the renal nerves. Journal of cardiovascular pharmacology. vol 11. issue 5. 1988-08-23. PMID:2455836. |
renal nerve stimulation (0.5 and 2.0 hz) did not significantly increase free renal venous or total dopamine sulfate content before or following administration of either cocaine or nomifensine. |
1988-08-23 |
2023-08-11 |
Not clear |
| F Karoum, R W Fawcett, R J Wyat. Chronic cocaine effects on peripheral biogenic amines: a long-term reduction in peripheral dopamine and phenylethylamine production. European journal of pharmacology. vol 148. issue 3. 1988-08-11. PMID:3384002. |
chronic cocaine effects on peripheral biogenic amines: a long-term reduction in peripheral dopamine and phenylethylamine production. |
1988-08-11 |
2023-08-11 |
rat |
| F Karoum, R W Fawcett, R J Wyat. Chronic cocaine effects on peripheral biogenic amines: a long-term reduction in peripheral dopamine and phenylethylamine production. European journal of pharmacology. vol 148. issue 3. 1988-08-11. PMID:3384002. |
the short- (during 12 h after last treatment) and long- (6 weeks after last treatment) term effects of repeated administration of cocaine on the total output of norepinephrine (ne) and its metabolites (sum ne), dopamine (da) and its metabolites (sum da) as well as the excretion of 5-hydroxyindoleacetic acid (5-hiaa) and phenylethylamine were evaluated in rats. |
1988-08-11 |
2023-08-11 |
rat |
| M C Ritz, R J Lamb, S R Goldberg, M J Kuha. Cocaine self-administration appears to be mediated by dopamine uptake inhibition. Progress in neuro-psychopharmacology & biological psychiatry. vol 12. issue 2-3. 1988-08-09. PMID:3387585. |
cocaine self-administration appears to be mediated by dopamine uptake inhibition. |
1988-08-09 |
2023-08-11 |
rat |
| M C Ritz, R J Lamb, S R Goldberg, M J Kuha. Cocaine self-administration appears to be mediated by dopamine uptake inhibition. Progress in neuro-psychopharmacology & biological psychiatry. vol 12. issue 2-3. 1988-08-09. PMID:3387585. |
thus, the cocaine receptor related to substance abuse appears to be the binding site associated with inhibition of dopamine uptake on the dopaminergic nerve terminals. |
1988-08-09 |
2023-08-11 |
rat |