Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
P Herridge, M S Gol. Pharmacological adjuncts in the treatment of opioid and cocaine addicts. Journal of psychoactive drugs. vol 20. issue 3. 1989-05-03. PMID:3069983. |
these agents potentiate dopaminergic transmission and in so doing tend to counter the dopamine depletion effect of prolonged cocaine use. |
1989-05-03 |
2023-08-11 |
Not clear |
D H Golwy. Cocaine abuse treated with phenelzine. The International journal of the addictions. vol 23. issue 9. 1989-04-28. PMID:3235232. |
phenelzine is thought to correct the biochemical defects caused by chronic cocaine use, namely the depletion of brain dopamine, norepinephrine, and serotonin. |
1989-04-28 |
2023-08-11 |
Not clear |
Y L Hurd, U Ungersted. Cocaine: an in vivo microdialysis evaluation of its acute action on dopamine transmission in rat striatum. Synapse (New York, N.Y.). vol 3. issue 1. 1989-04-04. PMID:2537539. |
cocaine: an in vivo microdialysis evaluation of its acute action on dopamine transmission in rat striatum. |
1989-04-04 |
2023-08-11 |
rat |
Y L Hurd, U Ungersted. Cocaine: an in vivo microdialysis evaluation of its acute action on dopamine transmission in rat striatum. Synapse (New York, N.Y.). vol 3. issue 1. 1989-04-04. PMID:2537539. |
the effects of cocaine on dopamine (da) neurotransmission were evaluated by in vivo microdialysis in the striatum of halothane-anesthetized rats. |
1989-04-04 |
2023-08-11 |
rat |
R P Hamme. Cocaine alters opiate receptor binding in critical brain reward regions. Synapse (New York, N.Y.). vol 3. issue 1. 1989-04-04. PMID:2537540. |
although cocaine action in the central nervous system is usually associated with altered dopamine function, we observed that opiate receptor density as labeled by [3h]naloxone was altered by chronic cocaine exposure in critical brain reward regions, including the nucleus accumbens, ventral pallidum, and lateral hypothalamus. |
1989-04-04 |
2023-08-11 |
rat |
M D Schechter, J W Boj. CGS 10746B is able to attenuate the effects of amphetamine: further evidence for dopaminergic mediation. Pharmacology, biochemistry, and behavior. vol 30. issue 4. 1989-04-04. PMID:2906435. |
these results implicate dopamine mechanisms in the discriminative stimulus properties of the psychostimulants amphetamine, cathinone and cocaine. |
1989-04-04 |
2023-08-11 |
rat |
E D Högestätt, O Johansson, K E Andersson, C M Kullendorf. Influence of renal denervation on vascular responsiveness of isolated rat intrarenal arteries. Acta physiologica Scandinavica. vol 132. issue 1. 1989-03-21. PMID:3223305. |
vasopressin, 5-hydroxytryptamine (5-ht), na (in the presence of cocaine), prostaglandin f2 alpha (pgf2 alpha) and dopamine (da) produced concentration-dependent contractions in the mentioned order of potency. |
1989-03-21 |
2023-08-11 |
rat |
G A Gerhardt, A Gratton, G M Ros. In vivo electrochemical studies of the effects of cocaine on dopamine nerve terminals in the rat neostriatum. Physiologia Bohemoslovaca. vol 37. issue 3. 1989-03-16. PMID:2975793. |
in vivo electrochemical studies of the effects of cocaine on dopamine nerve terminals in the rat neostriatum. |
1989-03-16 |
2023-08-11 |
rat |
G A Gerhardt, A Gratton, G M Ros. In vivo electrochemical studies of the effects of cocaine on dopamine nerve terminals in the rat neostriatum. Physiologia Bohemoslovaca. vol 37. issue 3. 1989-03-16. PMID:2975793. |
in vivo electrochemical measurements, involving chronoamperometric recordings using monoamine-selective nafion-coated electrodes, were used to study the effects of locally applied cocaine (50-500 micromolar barrel concentrations) on dopamine (da) nerve terminals in the neostriatum of the anaesthetized rat. |
1989-03-16 |
2023-08-11 |
rat |
J Willoughby, R F Cowburn, J A Hardy, V Glover, M Sandle. 1-Methyl-4-phenylpyridinium uptake by human and rat striatal synaptosomes. Journal of neurochemistry. vol 52. issue 2. 1989-02-23. PMID:2783454. |
uptake of mpp+ and dopamine into both rat and human synaptosomes was inhibited by cocaine and amfonelic acid, with the latter being five to 10 times more potent than the former. |
1989-02-23 |
2023-08-11 |
human |
L van Wolfswinkel, W F Seifert, J M van Re. Catecholamines and endogenous opioids in ventral tegmental self-stimulation reward. Pharmacology, biochemistry, and behavior. vol 30. issue 3. 1989-02-23. PMID:3211968. |
in the present experiment, the influence of graded doses of the dopamine antagonist haloperidol and of the agonist cocaine were investigated on electrical self-stimulation reward, elicited by electrodes located in the ventral tegmental area. |
1989-02-23 |
2023-08-11 |
rat |
M J Kuhar, M C Ritz, J Sharke. Cocaine receptors on dopamine transporters mediate cocaine-reinforced behavior. NIDA research monograph. vol 88. 1989-02-22. PMID:3145447. |
cocaine receptors on dopamine transporters mediate cocaine-reinforced behavior. |
1989-02-22 |
2023-08-11 |
Not clear |
W L Woolverton, M S Kleve. Multiple dopamine receptors and the behavioral effects of cocaine. NIDA research monograph. vol 88. 1989-02-22. PMID:3145448. |
multiple dopamine receptors and the behavioral effects of cocaine. |
1989-02-22 |
2023-08-11 |
Not clear |
L S Seiden, M S Kleve. Lack of toxic effects of cocaine on dopamine or serotonin neurons in the rat brain. NIDA research monograph. vol 88. 1989-02-22. PMID:3145452. |
lack of toxic effects of cocaine on dopamine or serotonin neurons in the rat brain. |
1989-02-22 |
2023-08-11 |
rat |
L C Nicolaysen, H T Pan, J B Justic. Extracellular cocaine and dopamine concentrations are linearly related in rat striatum. Brain research. vol 456. issue 2. 1989-02-21. PMID:3208083. |
extracellular cocaine and dopamine concentrations are linearly related in rat striatum. |
1989-02-21 |
2023-08-11 |
rat |
L C Nicolaysen, H T Pan, J B Justic. Extracellular cocaine and dopamine concentrations are linearly related in rat striatum. Brain research. vol 456. issue 2. 1989-02-21. PMID:3208083. |
cocaine dose, cocaine concentrations were found to be highly correlated (r = 0.963) with dopamine concentrations for the same point in time. |
1989-02-21 |
2023-08-11 |
rat |
L C Nicolaysen, H T Pan, J B Justic. Extracellular cocaine and dopamine concentrations are linearly related in rat striatum. Brain research. vol 456. issue 2. 1989-02-21. PMID:3208083. |
the slope was 36.8 nm dopamine/microm cocaine and the y-intercept was 29.9 nm dopamine. |
1989-02-21 |
2023-08-11 |
rat |
L C Nicolaysen, H T Pan, J B Justic. Extracellular cocaine and dopamine concentrations are linearly related in rat striatum. Brain research. vol 456. issue 2. 1989-02-21. PMID:3208083. |
maximum dopamine and maximum cocaine concentrations were also found to be linearly related to i.p. |
1989-02-21 |
2023-08-11 |
rat |
L J Ryan, M E Martone, J C Linder, P M Grove. Cocaine, in contrast to D-amphetamine, does not cause axonal terminal degeneration in neostriatum and agranular frontal cortex of Long-Evans rats. Life sciences. vol 43. issue 17. 1988-12-01. PMID:3185100. |
thus, cocaine resembles other catecholamine reuptake blockers and does not cause the neurodegenerative changes characteristic of other abused drugs that interact with the brain's dopamine systems. |
1988-12-01 |
2023-08-11 |
rat |
T R Kosten, H D Klebe. Rapid death during cocaine abuse: a variant of the neuroleptic malignant syndrome? The American journal of drug and alcohol abuse. vol 14. issue 3. 1988-11-30. PMID:3055940. |
the mechanism involves decreased postsynaptic availability of dopamine either through direct receptor blockade, as postulated in classical nms, or through relative dopamine depletion, as postulated in cocaine withdrawal. |
1988-11-30 |
2023-08-11 |
Not clear |