| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Grilli, A G Wright, I Hanbaue. Characterization of [3H]dopamine uptake sites and [3H]cocaine recognition sites in primary cultures of mesencephalic neurons during in vitro development. Journal of neurochemistry. vol 56. issue 6. 1991-06-12. PMID:2027018. |
[3h]dopamine uptake and [3h]cocaine binding sites were studied in primary cultures of ventral mesencephalon from 14-day-old rat embryos. |
1991-06-12 |
2023-08-11 |
rat |
| P Jatlow, J D Elsworth, C W Bradberry, G Winger, J R Taylor, R Russell, R H Rot. Cocaethylene: a neuropharmacologically active metabolite associated with concurrent cocaine-ethanol ingestion. Life sciences. vol 48. issue 18. 1991-05-30. PMID:2020260. |
since the powerful reinforcing effects of cocaine appear to be dependent on inhibition of dopamine reuptake in brain, we compared the effects of ec on the dopamine uptake system and its behavioral effects with those of cocaine. |
1991-05-30 |
2023-08-11 |
rat |
| P Jatlow, J D Elsworth, C W Bradberry, G Winger, J R Taylor, R Russell, R H Rot. Cocaethylene: a neuropharmacologically active metabolite associated with concurrent cocaine-ethanol ingestion. Life sciences. vol 48. issue 18. 1991-05-30. PMID:2020260. |
ec was equipotent to cocaine with respect to inhibition of binding of [3h]gbr 12935 to the dopamine reuptake complex, inhibition of [3h]dopamine uptake into synaptosomes and in its ability to increase extracellular dopamine concentration in the nucleus accumbens following its systemic administration to rats. |
1991-05-30 |
2023-08-11 |
rat |
| H O Pettit, J B Justic. Effect of dose on cocaine self-administration behavior and dopamine levels in the nucleus accumbens. Brain research. vol 539. issue 1. 1991-05-22. PMID:2015506. |
effect of dose on cocaine self-administration behavior and dopamine levels in the nucleus accumbens. |
1991-05-22 |
2023-08-11 |
Not clear |
| H O Pettit, J B Justic. Effect of dose on cocaine self-administration behavior and dopamine levels in the nucleus accumbens. Brain research. vol 539. issue 1. 1991-05-22. PMID:2015506. |
the reinforcing properties of cocaine are thought to be primarily mediated by the release of dopamine (da) in the nucleus accumbens (n acc). |
1991-05-22 |
2023-08-11 |
Not clear |
| G R Uhl, B O'Hara, S Shimada, R Zaczek, J DiGiorgianni, T Nishimor. Dopamine transporter: expression in Xenopus oocytes. Brain research. Molecular brain research. vol 9. issue 1-2. 1991-05-21. PMID:1850075. |
mrna-injected oocytes incubated with tritiated dopamine contain tritiated dopamine and metabolites; lower amounts of radiolabeled dopamine and more radiolabeled metabolites are found in oocytes co-incubated with cocaine or in water-injected oocytes. |
1991-05-21 |
2023-08-11 |
rat |
| C W Schindler, S R Tella, J M Witkin, S R Goldber. Effects of cocaine alone and in combination with haloperidol and SCH 23390 on cardiovascular function in squirrel monkeys. Life sciences. vol 48. issue 16. 1991-05-21. PMID:2016988. |
the potential involvement of d1 and d2 dopamine receptors in the effects of cocaine on cardiovascular function in squirrel monkeys was evaluated. |
1991-05-21 |
2023-08-11 |
monkey |
| C W Schindler, S R Tella, J M Witkin, S R Goldber. Effects of cocaine alone and in combination with haloperidol and SCH 23390 on cardiovascular function in squirrel monkeys. Life sciences. vol 48. issue 16. 1991-05-21. PMID:2016988. |
the pressor effects of cocaine do not appear to be controlled by selective dopamine receptors. |
1991-05-21 |
2023-08-11 |
monkey |
| M W Robertson, C A Leslie, J P Bennet. Apparent synaptic dopamine deficiency induced by withdrawal from chronic cocaine treatment. Brain research. vol 538. issue 2. 1991-05-16. PMID:2012975. |
apparent synaptic dopamine deficiency induced by withdrawal from chronic cocaine treatment. |
1991-05-16 |
2023-08-11 |
rat |
| M W Robertson, C A Leslie, J P Bennet. Apparent synaptic dopamine deficiency induced by withdrawal from chronic cocaine treatment. Brain research. vol 538. issue 2. 1991-05-16. PMID:2012975. |
the effects on motor behavior and forebrain dopamine (da) synaptic function of withdrawal from chronic cocaine treatment were examined with simultaneous activity monitoring and microdialysis in nucleus accumbens. |
1991-05-16 |
2023-08-11 |
rat |
| J P Ng, G W Hubert, J B Justic. Increased stimulated release and uptake of dopamine in nucleus accumbens after repeated cocaine administration as measured by in vivo voltammetry. Journal of neurochemistry. vol 56. issue 5. 1991-05-16. PMID:2013751. |
increased stimulated release and uptake of dopamine in nucleus accumbens after repeated cocaine administration as measured by in vivo voltammetry. |
1991-05-16 |
2023-08-11 |
rat |
| J P Ng, G W Hubert, J B Justic. Increased stimulated release and uptake of dopamine in nucleus accumbens after repeated cocaine administration as measured by in vivo voltammetry. Journal of neurochemistry. vol 56. issue 5. 1991-05-16. PMID:2013751. |
electrically stimulated dopamine (da) release (overflow) and uptake were measured with in vivo voltammetry in the nucleus accumbens (n acc) of anesthetized rats that had previously received repeated cocaine treatments. |
1991-05-16 |
2023-08-11 |
rat |
| H el-Bizri, I Guest, D R Varm. Effects of cocaine on rat embryo development in vivo and in cultures. Pediatric research. vol 29. issue 2. 1991-05-10. PMID:2014157. |
concentrations of dopamine, epinephrine, and norepinephrine in brains of fetuses or newborn pups (less than 12 h old) of cocaine (50 mumols/kg)-treated rats were not significantly elevated. |
1991-05-10 |
2023-08-11 |
rat |
| P B Silverma. Direct dopamine agonist-like activity conditioned to cocaine. Pharmacology, biochemistry, and behavior. vol 37. issue 2. 1991-04-26. PMID:2127852. |
direct dopamine agonist-like activity conditioned to cocaine. |
1991-04-26 |
2023-08-11 |
rat |
| F M Scalzo, S F Ali, N A Frambes, L P Spea. Weanling rats exposed prenatally to cocaine exhibit an increase in striatal D2 dopamine binding associated with an increase in ligand affinity. Pharmacology, biochemistry, and behavior. vol 37. issue 2. 1991-04-26. PMID:2150444. |
weanling rats exposed prenatally to cocaine exhibit an increase in striatal d2 dopamine binding associated with an increase in ligand affinity. |
1991-04-26 |
2023-08-11 |
rat |
| F M Scalzo, S F Ali, N A Frambes, L P Spea. Weanling rats exposed prenatally to cocaine exhibit an increase in striatal D2 dopamine binding associated with an increase in ligand affinity. Pharmacology, biochemistry, and behavior. vol 37. issue 2. 1991-04-26. PMID:2150444. |
alterations in d2 dopamine receptors may be associated with neurobehavioral alterations following prenatal cocaine exposure. |
1991-04-26 |
2023-08-11 |
rat |
| J L Katz, J M Witki. Behavioral effects of cocaine alone and in combination with selective dopamine antagonists in the squirrel monkey. Psychopharmacology. vol 103. issue 1. 1991-04-25. PMID:2006242. |
behavioral effects of cocaine alone and in combination with selective dopamine antagonists in the squirrel monkey. |
1991-04-25 |
2023-08-11 |
monkey |
| P M Callahan, J B Appel, K A Cunningha. Dopamine D1 and D2 mediation of the discriminative stimulus properties of d-amphetamine and cocaine. Psychopharmacology. vol 103. issue 1. 1991-04-25. PMID:2006243. |
dopamine d1 and d2 mediation of the discriminative stimulus properties of d-amphetamine and cocaine. |
1991-04-25 |
2023-08-11 |
rat |
| P M Callahan, J B Appel, K A Cunningha. Dopamine D1 and D2 mediation of the discriminative stimulus properties of d-amphetamine and cocaine. Psychopharmacology. vol 103. issue 1. 1991-04-25. PMID:2006243. |
evidence suggests that stimulants such as d-amphetamine and cocaine act presynaptically by increasing the amount of dopamine (da) available to stimulate postsynaptic da receptors. |
1991-04-25 |
2023-08-11 |
rat |
| J W Boja, M A Rahman, A Philip, A H Lewin, F I Carroll, M J Kuha. Isothiocyanate derivatives of cocaine: irreversible inhibition of ligand binding at the dopamine transporter. Molecular pharmacology. vol 39. issue 3. 1991-04-22. PMID:1826041. |
isothiocyanate derivatives of cocaine: irreversible inhibition of ligand binding at the dopamine transporter. |
1991-04-22 |
2023-08-11 |
rat |