| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J M Witkin, C W Schindler, S R Tella, S R Goldber. Interaction of haloperidol and SCH 23390 with cocaine and dopamine receptor subtype-selective agonists on schedule-controlled behavior of squirrel monkeys. Psychopharmacology. vol 104. issue 4. 1992-03-09. PMID:1838199. |
involvement of d1 and d2 dopamine receptors in the effects of cocaine on schedule-controlled behavior was evaluated in squirrel monkeys responding under a multiple fixed-interval 5-min, fixed-ratio 10 schedule (mult fi fr) of food delivery. |
1992-03-09 |
2023-08-11 |
monkey |
| A A Megens, F H Awouters, T F Meert, K H Schellekens, C J Niemegeers, P A Jansse. Pharmacological profile of the new potent neuroleptic ocaperidone (R 79,598). The Journal of pharmacology and experimental therapeutics. vol 260. issue 1. 1992-02-18. PMID:1370538. |
ocaperidone inhibited dopamine agonist (apomorphine, amphetamine or cocaine)-induced behavioral effects at low doses (0.014-0.042 mg/kg) and was, thereby, equipotent with haloperidol (0.016-0.024 mg/kg) and 2.0 to 8.3 times more potent than risperidone. |
1992-02-18 |
2023-08-11 |
Not clear |
| R D Spealman, J Bergman, B K Madra. Self-administration of the high-affinity cocaine analog 2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane. Pharmacology, biochemistry, and behavior. vol 39. issue 4. 1992-02-10. PMID:1763097. |
this potency relation corresponds closely with the potency relations reported for cft and cocaine in studies of dopamine uptake inhibition and binding at cocaine recognition sites. |
1992-02-10 |
2023-08-11 |
human |
| R D Spealman, J Bergman, B K Madra. Self-administration of the high-affinity cocaine analog 2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane. Pharmacology, biochemistry, and behavior. vol 39. issue 4. 1992-02-10. PMID:1763097. |
the results are consistent with the view that the reinforcing effects of cocaine-like drugs are mediated at cocaine recognition sites associated with the dopamine uptake system, and suggest that radioligand probes based on cft may be suitable markers for these sites. |
1992-02-10 |
2023-08-11 |
human |
| T B Usdin, E Mezey, C Chen, M J Brownstein, B J Hoffma. Cloning of the cocaine-sensitive bovine dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 24. 1992-02-07. PMID:1722321. |
[3h]dopamine accumulation in tissue culture cells transfected with the cdna was inhibited by amphetamine, cocaine, and specific inhibitors of dopamine transport, including gbr12909. |
1992-02-07 |
2023-08-11 |
human |
| L Zhang, J E Barret. Imipramine as a discriminative stimulus. The Journal of pharmacology and experimental therapeutics. vol 259. issue 3. 1992-02-07. PMID:1762063. |
the psychomotor stimulants cocaine and d-amphetamine also occasioned responding on the imipramine key, as did the ne reuptake inhibitor tomoxetine; nomifensine, which blocks the reuptake of both ne and dopamine (da), also resulted in responding on the key correlated with imipramine injections. |
1992-02-07 |
2023-08-11 |
Not clear |
| M S Kleven, L S Seide. Repeated injection of cocaine potentiates methamphetamine-induced toxicity to dopamine-containing neurons in rat striatum. Brain research. vol 557. issue 1-2. 1992-01-22. PMID:1747766. |
repeated daily administration of cocaine potentiated the long-lasting striatal dopamine depletions caused by methamphetamine. |
1992-01-22 |
2023-08-11 |
human |
| S J Yi, A N Gifford, K M Johnso. Effect of cocaine and 5-HT3 receptor antagonists on 5-HT-induced [3H]dopamine release from rat striatal synaptosomes. European journal of pharmacology. vol 199. issue 2. 1991-12-30. PMID:1835440. |
effect of cocaine and 5-ht3 receptor antagonists on 5-ht-induced [3h]dopamine release from rat striatal synaptosomes. |
1991-12-30 |
2023-08-11 |
rat |
| J D Steketee, P W Kaliva. Sensitization to psychostimulants and stress after injection of pertussis toxin into the A10 dopamine region. The Journal of pharmacology and experimental therapeutics. vol 259. issue 2. 1991-12-24. PMID:1941636. |
we hypothesize that the sensitized responses to cocaine, amphetamine and stress produced by ptx results from a decrease in dopamine d2 and gabab-mediated inhibitory control of a10 dopamine neurons. |
1991-12-24 |
2023-08-11 |
Not clear |
| B A Baldo, A E Kelle. Cross-sensitization between cocaine and GBR 12909, a dopamine uptake inhibitor. Brain research bulletin. vol 27. issue 1. 1991-12-23. PMID:1834316. |
cross-sensitization between cocaine and gbr 12909, a dopamine uptake inhibitor. |
1991-12-23 |
2023-08-11 |
rat |
| B A Baldo, A E Kelle. Cross-sensitization between cocaine and GBR 12909, a dopamine uptake inhibitor. Brain research bulletin. vol 27. issue 1. 1991-12-23. PMID:1834316. |
in the present experiment, rats which had received repeated injections of 20 mg/kg gbr 12909, a selective dopamine uptake inhibitor, were subjected to challenge doses of gbr 12909 and cocaine which were near or below the threshold for locomotor activation in drug-naive animals. |
1991-12-23 |
2023-08-11 |
rat |
| H A Robertson, M L Paul, R Moratalla, A M Graybie. Expression of the immediate early gene c-fos in basal ganglia: induction by dopaminergic drugs. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 18. issue 3 Suppl. 1991-12-19. PMID:1682022. |
directly-acting dopamine agonists of the d1-type (skf 38393, cy 208-243) and indirectly-acting dopamine agonists (amphetamine, cocaine) all produce a rapid and transient increase in fos protein levels in varying patterns in striatum and cerebral cortex. |
1991-12-19 |
2023-08-11 |
Not clear |
| H A Robertson, M L Paul, R Moratalla, A M Graybie. Expression of the immediate early gene c-fos in basal ganglia: induction by dopaminergic drugs. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 18. issue 3 Suppl. 1991-12-19. PMID:1682022. |
directly-acting dopamine agonists only produce c-fos activation in denervated (supersensitive) striatum whereas cocaine and amphetamine activate c-fos in striatum in naive animals. |
1991-12-19 |
2023-08-11 |
Not clear |
| R K Conlee, D W Barnett, K P Kelly, D H Ha. Effects of cocaine, exercise, and resting conditions on plasma corticosterone and catecholamine concentrations in the rat. Metabolism: clinical and experimental. vol 40. issue 10. 1991-12-19. PMID:1943729. |
in this study, rats under the influence of cocaine (12.5 mg/kg, intraperitoneally [ip]) or saline were exposed to a variety of resting conditions, as well as exercise (running, 26 m/min, 10% grade, for 30 minutes), to evaluate the amount of stress imposed by these conditions as determined by the changes in the plasma concentrations of corticosterone (c) and catecholamines (norepinephrine [ne], epinephrine [e], dopamine [da]). |
1991-12-19 |
2023-08-11 |
rat |
| M J Kuhar, M C Ritz, J W Boj. The dopamine hypothesis of the reinforcing properties of cocaine. Trends in neurosciences. vol 14. issue 7. 1991-12-02. PMID:1719677. |
the dopamine hypothesis of the reinforcing properties of cocaine. |
1991-12-02 |
2023-08-11 |
Not clear |
| M J Kuhar, M C Ritz, J W Boj. The dopamine hypothesis of the reinforcing properties of cocaine. Trends in neurosciences. vol 14. issue 7. 1991-12-02. PMID:1719677. |
this hypothesis proposes that cocaine binds at the dopamine transporter and mainly inhibits neurotransmitter re-uptake; the resulting potentiation of dopaminergic neurotransmission in mesolimbocortical pathways ultimately causes reinforcement. |
1991-12-02 |
2023-08-11 |
Not clear |
| D W Clow, R P Hammer, C L Kirstein, L P Spea. Gestational cocaine exposure increases opiate receptor binding in weanling offspring. Brain research. Developmental brain research. vol 59. issue 2. 1991-11-18. PMID:1655306. |
gestational cocaine exposure is known to affect developing dopamine systems, but other neurochemical systems may also be at risk. |
1991-11-18 |
2023-08-11 |
rat |
| J R Simon, H Yu, J A Richter, M R Vasko, B Ghett. In vitro release of endogenous dopamine from the striatum of the weaver mutant mouse. Journal of neurochemistry. vol 57. issue 5. 1991-11-15. PMID:1919570. |
in both genotypes, release evoked by amphetamine was completely inhibited by cocaine, implicating the dopamine uptake carrier in this release process. |
1991-11-15 |
2023-08-11 |
mouse |
| Z Sarnyai, G Szabó, G L Kovács, G Telegd. Oxytocin attenuates the cocaine-induced exploratory hyperactivity in mice. Neuroreport. vol 1. issue 3-4. 1991-11-08. PMID:1983356. |
in the nucleus accumbens, oxytocin antagonized the increased dopamine disappearance, elicited by cocaine, but not in the nucleus caudatus. |
1991-11-08 |
2023-08-11 |
mouse |
| R Peltier, S Schen. GR38032F, a serotonin 5-HT3 antagonist, fails to alter cocaine self-administration in rats. Pharmacology, biochemistry, and behavior. vol 39. issue 1. 1991-11-01. PMID:1833779. |
to assess this possibility, we compared the effects of the 5-ht3 antagonist, gr38032f, with the dopamine d2 receptor blocker, haloperidol, on the intravenous self-administration of cocaine (0.5 mg/kg/infusion) in rats. |
1991-11-01 |
2023-08-11 |
rat |