| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R A Vaughan, R Simantov, R Lew, M J Kuha. A rapid binding assay for solubilized dopamine transporters using [3H]WIN 35,428. Journal of neuroscience methods. vol 40. issue 1. 1992-04-08. PMID:1795555. |
the cocaine analog [3h]win 35,428 was used to label digitonin-solubilized dopamine transporters from dog caudate nucleus. |
1992-04-08 |
2023-08-11 |
dog |
| M J Kaufman, B K Madra. Severe depletion of cocaine recognition sites associated with the dopamine transporter in Parkinson's-diseased striatum. Synapse (New York, N.Y.). vol 9. issue 1. 1992-04-08. PMID:1796351. |
severe depletion of cocaine recognition sites associated with the dopamine transporter in parkinson's-diseased striatum. |
1992-04-08 |
2023-08-11 |
human |
| M J Kaufman, B K Madra. Severe depletion of cocaine recognition sites associated with the dopamine transporter in Parkinson's-diseased striatum. Synapse (New York, N.Y.). vol 9. issue 1. 1992-04-08. PMID:1796351. |
the cocaine congener [3h]cft, also designated [3h]win 35,428 (2 beta-carbomethoxy-3 beta-(4-fluorophenyltropane), labels cocaine receptors associated with the dopamine transporter in primate striatum. |
1992-04-08 |
2023-08-11 |
human |
| M J Kaufman, B K Madra. Severe depletion of cocaine recognition sites associated with the dopamine transporter in Parkinson's-diseased striatum. Synapse (New York, N.Y.). vol 9. issue 1. 1992-04-08. PMID:1796351. |
the marked decrease of [3h]cft binding sites in parkinson's diseased striatum supports the following conclusions: 1) the dopamine transporter is localized primarily on presynaptic nigrostriatal terminals; 2) in the caudate and putamen, cocaine recognition sites are associated primarily with the dopamine transporter; 3) the low level of nonspecific binding of [3h]cft and the marked depletion of [3h]cft-labeled sites suggest that radiolabeled derivatives of cft or its congeners may be suitable imaging probes for presynaptic dopamine nerve terminals. |
1992-04-08 |
2023-08-11 |
human |
| L H Parsons, A D Smith, J B Justic. Basal extracellular dopamine is decreased in the rat nucleus accumbens during abstinence from chronic cocaine. Synapse (New York, N.Y.). vol 9. issue 1. 1992-04-08. PMID:1796352. |
basal extracellular dopamine is decreased in the rat nucleus accumbens during abstinence from chronic cocaine. |
1992-04-08 |
2023-08-11 |
rat |
| L Hernandez, N A Guzman, B G Hoebe. Bidirectional microdialysis in vivo shows differential dopaminergic potency of cocaine, procaine and lidocaine in the nucleus accumbens using capillary electrophoresis for calibration of drug outward diffusion. Psychopharmacology. vol 105. issue 2. 1992-04-07. PMID:1796132. |
cocaine (7.3 mm) increased the extracellular concentration of dopamine (da). |
1992-04-07 |
2023-08-11 |
rat |
| L Hernandez, N A Guzman, B G Hoebe. Bidirectional microdialysis in vivo shows differential dopaminergic potency of cocaine, procaine and lidocaine in the nucleus accumbens using capillary electrophoresis for calibration of drug outward diffusion. Psychopharmacology. vol 105. issue 2. 1992-04-07. PMID:1796132. |
five conclusions are drawn: (1) this confirms our earlier finding that local injection of cocaine increases extracellular da, but in this case the cocaine was infused via the probe without disturbing the animal; (2) the action of cocaine on dopamine terminals in the accumbens is independent of local anesthesia; (3) procaine may enhance mood by a cocaine-like effect; (4) capillary electrophoresis has potential for measuring cocaine levels in small samples and (5) in vitro calibrations are of limited value to evaluate in vivo performance of microdialysis probes. |
1992-04-07 |
2023-08-11 |
rat |
| C B Hubner, J E Moreto. Effects of selective D1 and D2 dopamine antagonists on cocaine self-administration in the rat. Psychopharmacology. vol 105. issue 2. 1992-04-07. PMID:1839063. |
effects of selective d1 and d2 dopamine antagonists on cocaine self-administration in the rat. |
1992-04-07 |
2023-08-11 |
rat |
| M E Reith, G Selmec. Cocaine binding sites in mouse striatum, dopamine autoreceptors, and cocaine-induced locomotion. Pharmacology, biochemistry, and behavior. vol 41. issue 1. 1992-04-02. PMID:1311455. |
cocaine binding sites in mouse striatum, dopamine autoreceptors, and cocaine-induced locomotion. |
1992-04-02 |
2023-08-11 |
mouse |
| M E Reith, G Selmec. Cocaine binding sites in mouse striatum, dopamine autoreceptors, and cocaine-induced locomotion. Pharmacology, biochemistry, and behavior. vol 41. issue 1. 1992-04-02. PMID:1311455. |
factors other than striatal cocaine binding sites, or dopamine autoreceptors as measured by apomorphine-induced depression of locomotion, should be considered for the explanation of the enhancement of the locomotor response upon daily cocaine administration in balb/cbyj mice, or for the different locomotor response to cocaine of this strain compared with the c57bl/6byj strain of mice. |
1992-04-02 |
2023-08-11 |
mouse |
| P Lomax, K A Danie. Cocaine and body temperature in the rat: effect of dopamine D1 antagonists. Proceedings of the Western Pharmacology Society. vol 34. 1992-03-20. PMID:1838610. |
cocaine and body temperature in the rat: effect of dopamine d1 antagonists. |
1992-03-20 |
2023-08-11 |
rat |
| B A Sorg, P W Kaliva. Effects of cocaine and footshock stress on extracellular dopamine levels in the ventral striatum. Brain research. vol 559. issue 1. 1992-03-19. PMID:1782559. |
effects of cocaine and footshock stress on extracellular dopamine levels in the ventral striatum. |
1992-03-19 |
2023-08-11 |
rat |
| B A Sorg, P W Kaliva. Effects of cocaine and footshock stress on extracellular dopamine levels in the ventral striatum. Brain research. vol 559. issue 1. 1992-03-19. PMID:1782559. |
the effects of stress and cocaine on extracellular levels of dopamine and its metabolites, 3,4-dihydroxyphenylacetic acid (dopac) and homovanillic acid (hva), were measured by in vivo microdialysis in the rostral ventral striatum, including the nucleus accumbens. |
1992-03-19 |
2023-08-11 |
rat |
| W A Corrigall, K M Coe. Cocaine self-administration is increased by both D1 and D2 dopamine antagonists. Pharmacology, biochemistry, and behavior. vol 39. issue 3. 1992-03-19. PMID:1838414. |
cocaine self-administration is increased by both d1 and d2 dopamine antagonists. |
1992-03-19 |
2023-08-11 |
rat |
| R D Crosby, J A Halikas, G Carlso. Pharmacotherapeutic interventions for cocaine abuse: present practices and future directions. Journal of addictive diseases. vol 10. issue 4. 1992-03-12. PMID:1685672. |
animal observations related to dopamine depletion, receptor supersensitivity, cocaine-induced kindling, and serotonin depletion have all generated pharmacotherapeutic interventions for cocaine abuse. |
1992-03-12 |
2023-08-11 |
Not clear |
| S Izenwasser, J G Rosenberger, B M Co. Inhibition of [3H]dopamine and [3H]serotonin uptake by cocaine: comparison between chopped tissue slices and synaptosomes. Life sciences. vol 50. issue 8. 1992-03-12. PMID:1736024. |
inhibition of [3h]dopamine and [3h]serotonin uptake by cocaine: comparison between chopped tissue slices and synaptosomes. |
1992-03-12 |
2023-08-11 |
rat |
| S Izenwasser, J G Rosenberger, B M Co. Inhibition of [3H]dopamine and [3H]serotonin uptake by cocaine: comparison between chopped tissue slices and synaptosomes. Life sciences. vol 50. issue 8. 1992-03-12. PMID:1736024. |
cocaine inhibits both [3h]dopamine and [3h]serotonin uptake in rat striatum and nucleus accumbens. |
1992-03-12 |
2023-08-11 |
rat |
| D Rapoza, W L Woolverto. Attenuation of the effects of cocaine on milk consumption in rats by dopamine antagonists. Pharmacology, biochemistry, and behavior. vol 40. issue 1. 1992-03-10. PMID:1838194. |
attenuation of the effects of cocaine on milk consumption in rats by dopamine antagonists. |
1992-03-10 |
2023-08-11 |
rat |
| R W Rockhold, E S Carver, Y Ishizuka, B Hoskins, I K H. Dopamine receptors mediate cocaine-induced temperature responses in spontaneously hypertensive and Wistar-Kyoto rats. Pharmacology, biochemistry, and behavior. vol 40. issue 1. 1992-03-10. PMID:1838195. |
the involvement of dopaminergic receptors in the responses of conscious, restrained spontaneously hypertensive (shr) and wistar-kyoto (wky) rats to cocaine was examined using antagonists selective for da-1 (sch 23390) or da-2 (sulpiride) dopamine receptors. |
1992-03-10 |
2023-08-11 |
rat |
| J M Paris, K A Cunningha. Serotonin 5-HT3 antagonists do not alter the discriminative stimulus properties of cocaine. Psychopharmacology. vol 104. issue 4. 1992-03-09. PMID:1780417. |
behavioral evidence suggests that 5-ht3 receptors interact with mesolimbic dopamine (da) systems and that 5-ht3 antagonists can interfere with the hyperlocomotive effects of amphetamine and cocaine and the rewarding and stimulus effects of morphine, nicotine and ethanol. |
1992-03-09 |
2023-08-11 |
rat |