| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Izenwasser, B M Co. Inhibition of dopamine uptake by cocaine and nicotine: tolerance to chronic treatments. Brain research. vol 573. issue 1. 1992-06-08. PMID:1576529. |
chronic administration of cocaine (50 mg/kg/day for 7 days, s.c. via an osmotic minipump) produced tolerance to inhibition of [3h]dopamine uptake by cocaine in rat striatum but did not produce cross-tolerance to inhibition of [3h]dopamine uptake by nicotine. |
1992-06-08 |
2023-08-11 |
rat |
| S Izenwasser, B M Co. Inhibition of dopamine uptake by cocaine and nicotine: tolerance to chronic treatments. Brain research. vol 573. issue 1. 1992-06-08. PMID:1576529. |
chronic nicotinic treatment (6 mg/kg/day for 7 days, s.c. via an osmotic minipump), however, produced tolerance to the inhibition of [3h]dopamine uptake by nicotine and cross-tolerance to inhibition of uptake by cocaine in rat striatum. |
1992-06-08 |
2023-08-11 |
rat |
| S Izenwasser, B M Co. Inhibition of dopamine uptake by cocaine and nicotine: tolerance to chronic treatments. Brain research. vol 573. issue 1. 1992-06-08. PMID:1576529. |
unlike the effects on [3h]dopamine uptake, chronic cocaine infusion did not have any effect on the ability of cocaine to inhibit [3h]serotonin uptake in either brain region. |
1992-06-08 |
2023-08-11 |
rat |
| J D Steketee, P W Kaliva. Microinjection of the D2 agonist quinpirole into the A10 dopamine region blocks amphetamine-, but not cocaine-stimulated motor activity. The Journal of pharmacology and experimental therapeutics. vol 261. issue 2. 1992-06-05. PMID:1349649. |
it is suggested that the different mechanisms of action of cocaine and amphetamine, uptake blocker vs. releaser or longloop vs. shortloop feedback inhibition of a10 dopamine neurons, respectively, may account for the differential effects that quinpirole had in blocking the motor-stimulant response to these psychostimulants. |
1992-06-05 |
2023-08-11 |
Not clear |
| Y L Hurd, E E Brown, J M Finlay, H C Fibiger, C R Gerfe. Cocaine self-administration differentially alters mRNA expression of striatal peptides. Brain research. Molecular brain research. vol 13. issue 1-2. 1992-06-05. PMID:1374504. |
cocaine, an indirect dopamine agonist, was found to differentially affect the levels of mrna encoding these neuropeptides in different subregions of the striatum. |
1992-06-05 |
2023-08-11 |
rat |
| M J Akpaffiong, P Rui. Neuroleptic malignant syndrome: a complication of neuroleptics and cocaine abuse. The Psychiatric quarterly. vol 62. issue 4. 1992-05-28. PMID:1687338. |
thus we argue that psychiatric patients with a history of cocaine abuse may be more at risk of developing neuroleptic malignant syndrome when treated with neuroleptics, possibly associated with the blockade of dopamine (d2-receptors) by neuroleptics and the activation of dopamine/5-ht receptors by cocaine-induced dopamine. |
1992-05-28 |
2023-08-11 |
Not clear |
| H R Kranzler, D J Wallingto. Serum prolactin level, craving, and early discharge from treatment in cocaine-dependent patients. The American journal of drug and alcohol abuse. vol 18. issue 2. 1992-05-14. PMID:1314018. |
this lack of intercorrelation argues against the notion that dopamine depletion is an adequate explanation for both craving and hyperprolactinemia following chronic cocaine use. |
1992-05-14 |
2023-08-11 |
Not clear |
| R B Rothman, A Mele, A A Reid, H C Akunne, N Greig, A Thurkauf, B R de Costa, K C Rice, A Per. GBR12909 antagonizes the ability of cocaine to elevate extracellular levels of dopamine. Pharmacology, biochemistry, and behavior. vol 40. issue 2. 1992-05-04. PMID:1839568. |
gbr12909 antagonizes the ability of cocaine to elevate extracellular levels of dopamine. |
1992-05-04 |
2023-08-11 |
rat |
| F I Carroll, A H Lewin, J W Boja, M J Kuha. Cocaine receptor: biochemical characterization and structure-activity relationships of cocaine analogues at the dopamine transporter. Journal of medicinal chemistry. vol 35. issue 6. 1992-04-28. PMID:1552510. |
cocaine receptor: biochemical characterization and structure-activity relationships of cocaine analogues at the dopamine transporter. |
1992-04-28 |
2023-08-11 |
Not clear |
| I S McGregor, D M Atrens, D M Jackso. Cocaine facilitation of prefrontal cortex self-stimulation: a microstructural and pharmacological analysis. Psychopharmacology. vol 106. issue 2. 1992-04-22. PMID:1312730. |
the acute effects of cocaine on mpc self-stimulation were completely reversed by the dopamine (da) d1 antagonist sch 23390 0.02 mg/kg) and the d2 antagonist raclopride (0.3 mg/kg) but not by naloxone (0.5 mg/kg). |
1992-04-22 |
2023-08-11 |
rat |
| L D Manley, R Kuczenski, D S Segal, S J Young, P M Grove. Effects of frequency and pattern of medial forebrain bundle stimulation on caudate dialysate dopamine and serotonin. Journal of neurochemistry. vol 58. issue 4. 1992-04-17. PMID:1548482. |
extracellular dopamine concentrations increased linearly as a function of the frequency (4-33 hz) of evenly spaced stimuli in both the presence and absence of cocaine added to the dialysate. |
1992-04-17 |
2023-08-11 |
rat |
| L D Manley, R Kuczenski, D S Segal, S J Young, P M Grove. Effects of frequency and pattern of medial forebrain bundle stimulation on caudate dialysate dopamine and serotonin. Journal of neurochemistry. vol 58. issue 4. 1992-04-17. PMID:1548482. |
the response of extracellular dopamine was augmented in both the presence and absence of cocaine when the same number of stimuli were delivered in bursts as compared to an evenly spaced pattern. |
1992-04-17 |
2023-08-11 |
rat |
| L D Manley, R Kuczenski, D S Segal, S J Young, P M Grove. Effects of frequency and pattern of medial forebrain bundle stimulation on caudate dialysate dopamine and serotonin. Journal of neurochemistry. vol 58. issue 4. 1992-04-17. PMID:1548482. |
serotonin, which was only assessed in the presence of cocaine, similarly increased linearly with frequency, but, in contrast to the dopamine response, levels of serotonin were not augmented by stimuli presented in bursts. |
1992-04-17 |
2023-08-11 |
rat |
| Z L Rossetti, P S D'Aquila, Y Hmaidan, G L Gessa, G Serr. Repeated treatment with imipramine potentiates cocaine-induced dopamine release and motor stimulation. European journal of pharmacology. vol 201. issue 2-3. 1992-04-16. PMID:1665784. |
the stimulatory effect of cocaine on locomotor activity and on dopamine efflux from the ventral striatum was studied in rats chronically treated with the antidepressant imipramine. |
1992-04-16 |
2023-08-11 |
rat |
| Z L Rossetti, P S D'Aquila, Y Hmaidan, G L Gessa, G Serr. Repeated treatment with imipramine potentiates cocaine-induced dopamine release and motor stimulation. European journal of pharmacology. vol 201. issue 2-3. 1992-04-16. PMID:1665784. |
the results indicate that chronic imipramine facilitates mesolimbic dopamine neurotransmission by potentiating the mechanism which is thought to mediate the rewarding effects of cocaine. |
1992-04-16 |
2023-08-11 |
rat |
| N B Mercuri, F Stratta, P Calabresi, G Bernard. Electrophysiological effects of amineptine on neurones of the rat substantia nigra pars compacta: evidence for an inhibition of the dopamine uptake system. British journal of pharmacology. vol 104. issue 3. 1992-04-16. PMID:1797329. |
amineptine (300 nm-30 microm) and cocaine (10-30 microm) increased the amplitude and duration of responses to exogenously applied dopamine. |
1992-04-16 |
2023-08-11 |
rat |
| R L Balster, F I Carroll, J H Graham, R S Mansbach, M A Rahman, A Philip, A H Lewin, V M Showalte. Potent substituted-3 beta-phenyltropane analogs of cocaine have cocaine-like discriminative stimulus effects. Drug and alcohol dependence. vol 29. issue 2. 1992-04-16. PMID:1797525. |
the potent cocaine-like effects of the rti analogs in vivo correspond with their high affinities for a cocaine recognition site on the dopamine transporter, providing further evidence that this site may mediate behavioral effects of cocaine relevant to its abuse. |
1992-04-16 |
2023-08-11 |
rat |
| L G Sharpe, N S Pilotte, W M Mitchell, E B De Souz. Withdrawal of repeated cocaine decreases autoradiographic [3H]mazindol-labelling of dopamine transporter in rat nucleus accumbens. European journal of pharmacology. vol 203. issue 1. 1992-04-16. PMID:1797552. |
withdrawal of repeated cocaine decreases autoradiographic [3h]mazindol-labelling of dopamine transporter in rat nucleus accumbens. |
1992-04-16 |
2023-08-11 |
rat |
| L G Sharpe, N S Pilotte, W M Mitchell, E B De Souz. Withdrawal of repeated cocaine decreases autoradiographic [3H]mazindol-labelling of dopamine transporter in rat nucleus accumbens. European journal of pharmacology. vol 203. issue 1. 1992-04-16. PMID:1797552. |
down-regulation of the dopamine transporter in the nucleus accumbens by withdrawal of chronic cocaine may be one of the mechanisms involved in cocaine's long-term abstinence effects. |
1992-04-16 |
2023-08-11 |
rat |
| J M Tepper, I Creese, D H Schwart. Stimulus-evoked changes in neostriatal dopamine levels in awake and anesthetized rats as measured by microdialysis. Brain research. vol 559. issue 2. 1992-04-08. PMID:1794102. |
when the perfusion solution contained 1.2 mm ca2+, even intense, high frequency stimulation was ineffective at producing significant elevations in neostriatal dopamine levels whereas cocaine or amphetamine reliably caused several-fold elevations in dopamine levels. |
1992-04-08 |
2023-08-11 |
rat |