| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R D Spealman, J Bergman, B K Madras, K F Meli. Discriminative stimulus effects of cocaine in squirrel monkeys: involvement of dopamine receptor subtypes. The Journal of pharmacology and experimental therapeutics. vol 258. issue 3. 1991-10-17. PMID:1679852. |
the involvement of dopamine (da) receptor subtypes in the discriminative stimulus effects of cocaine was investigated in squirrel monkeys trained to discriminate cocaine from vehicle using a two-lever choice procedure. |
1991-10-17 |
2023-08-11 |
monkey |
| D J Henry, F J Whit. Repeated cocaine administration causes persistent enhancement of D1 dopamine receptor sensitivity within the rat nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 258. issue 3. 1991-10-17. PMID:1890623. |
the rewarding effects of cocaine are mediated primarily by the mesoaccumbens dopamine (da) system, which projects from a10 da cell bodies within the ventral tegmental area to the nucleus accumbens (nac). |
1991-10-17 |
2023-08-11 |
rat |
| R Kuczenski, D S Segal, M L Aizenstei. Amphetamine, cocaine, and fencamfamine: relationship between locomotor and stereotypy response profiles and caudate and accumbens dopamine dynamics. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 11. issue 9. 1991-10-03. PMID:1715389. |
amphetamine, cocaine, and fencamfamine: relationship between locomotor and stereotypy response profiles and caudate and accumbens dopamine dynamics. |
1991-10-03 |
2023-08-11 |
rat |
| R Kuczenski, D S Segal, M L Aizenstei. Amphetamine, cocaine, and fencamfamine: relationship between locomotor and stereotypy response profiles and caudate and accumbens dopamine dynamics. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 11. issue 9. 1991-10-03. PMID:1715389. |
using in vivo microdialysis, the caudate and nucleus accumbens dopamine (da) responses to the psychomotor stimulants amphetamine (amph), cocaine (coc), and fencamfamine (fcf) were evaluated in rats concurrent with characterization of their behavioral response profiles. |
1991-10-03 |
2023-08-11 |
rat |
| K A Cunningham, P M Callaha. Monoamine reuptake inhibitors enhance the discriminative state induced by cocaine in the rat. Psychopharmacology. vol 104. issue 2. 1991-09-26. PMID:1831559. |
cocaine inhibits the reuptake of dopamine (da), norepinephrine (ne), and serotonin (5-ht). |
1991-09-26 |
2023-08-11 |
rat |
| W A Corrigall, K M Coe. Selective dopamine antagonists reduce nicotine self-administration. Psychopharmacology. vol 104. issue 2. 1991-09-26. PMID:1876661. |
the effects of dopamine antagonists on nicotine self-administration are different from the effects of these antagonists on cocaine self-administration. |
1991-09-26 |
2023-08-11 |
rat |
| R B Rothman, A Mele, A A Reid, H Akunne, N Grieg, A Thurkauf, B R deCosta, K C Rice, A Per. Preliminary evidence that the high affinity dopamine reuptake inhibitor, GBR12909, antagonizes the ability of cocaine to elevate extracellular levels of dopamine. NIDA research monograph. vol 105. 1991-09-20. PMID:1831540. |
preliminary evidence that the high affinity dopamine reuptake inhibitor, gbr12909, antagonizes the ability of cocaine to elevate extracellular levels of dopamine. |
1991-09-20 |
2023-08-11 |
Not clear |
| P Jatlow, W L Hearn, J D Elsworth, R H Roth, C W Bradberry, J R Taylo. Cocaethylene inhibits uptake of dopamine and can reach high plasma concentrations following combined cocaine and ethanol use. NIDA research monograph. vol 105. 1991-09-20. PMID:1876124. |
cocaethylene inhibits uptake of dopamine and can reach high plasma concentrations following combined cocaine and ethanol use. |
1991-09-20 |
2023-08-11 |
Not clear |
| J D Steketee, P W Kaliva. Sensitization to cocaine produced by injection of pertussis toxin into the A10 dopamine region. NIDA research monograph. vol 105. 1991-09-20. PMID:1908559. |
sensitization to cocaine produced by injection of pertussis toxin into the a10 dopamine region. |
1991-09-20 |
2023-08-11 |
Not clear |
| K F Melia, R D Spealma. Pharmacological characterization of the discriminative-stimulus effects of GBR 12909. The Journal of pharmacology and experimental therapeutics. vol 258. issue 2. 1991-09-11. PMID:1678014. |
dopamine uptake inhibitors, including gbr 12909, cocaine, 2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane, mazindol, bupropion and methylphenidate, as well as the dopamine releasing drug (+)-amphetamine substituted fully (greater than 80% drug-lever responding) for the training dose of gbr 12909. |
1991-09-11 |
2023-08-11 |
monkey |
| N B Mercuri, P Calabresi, G Bernard. Dopamine uptake inhibition potentiates the effects of L-DOPA on rat substantia nigra zona compacta neurons. Neuroscience letters. vol 126. issue 1. 1991-09-10. PMID:1830942. |
intracellular electrophysiological recordings (current and voltage-clamp mode) were used to assess whether the actions of l-dopa on rat substantia nigra zona compacta neurons maintained in vitro are potentiated by drugs that block the dopamine uptake system (cocaine and nomifensine). |
1991-09-10 |
2023-08-11 |
rat |
| S Pögün, U Scheffel, M J Kuha. Cocaine displaces [3H]WIN 35,428 binding to dopamine uptake sites in vivo more rapidly than mazindol or GBR 12909. European journal of pharmacology. vol 198. issue 2-3. 1991-09-10. PMID:1864307. |
cocaine displaces [3h]win 35,428 binding to dopamine uptake sites in vivo more rapidly than mazindol or gbr 12909. |
1991-09-10 |
2023-08-11 |
Not clear |
| S Pögün, U Scheffel, M J Kuha. Cocaine displaces [3H]WIN 35,428 binding to dopamine uptake sites in vivo more rapidly than mazindol or GBR 12909. European journal of pharmacology. vol 198. issue 2-3. 1991-09-10. PMID:1864307. |
previous studies have shown that [3h] win 35,428 binds preferentially to striatal cocaine receptors at the dopamine transporter after in vivo injection. |
1991-09-10 |
2023-08-11 |
Not clear |
| H M Jacocks, S Izenwasser, L L Werling, B M Co. Comparison of dopamine uptake and release in vitro in sheep and rat striatum. Life sciences. vol 49. issue 7. 1991-09-05. PMID:1830633. |
cocaine inhibits tritium-labeled dopamine ([3h]da) uptake in rat (ic50 approximately 400 nm) and sheep (ic50 approximately 1 microm) striatum. |
1991-09-05 |
2023-08-11 |
rat |
| J D Steketee, C D Striplin, T F Murray, P W Kaliva. Possible role for G-proteins in behavioral sensitization to cocaine. Brain research. vol 545. issue 1-2. 1991-08-30. PMID:1907213. |
the role of g-proteins in behavioral sensitization to cocaine was examined by injecting pertussis toxin (ptx) into the a10 dopamine cell group. |
1991-08-30 |
2023-08-11 |
rat |
| J D Steketee, C D Striplin, T F Murray, P W Kaliva. Possible role for G-proteins in behavioral sensitization to cocaine. Brain research. vol 545. issue 1-2. 1991-08-30. PMID:1907213. |
the capacity of acute cocaine to increase motor activity and dopamine release in the nucleus accumbens was significantly augmented in rats pretreated 14 days earlier with ptx. |
1991-08-30 |
2023-08-11 |
rat |
| C A Jimenez-Rivera, B D Waterhous. Effects of systemically and locally applied cocaine on cerebrocortical neuron responsiveness to afferent synaptic inputs and glutamate. Brain research. vol 546. issue 2. 1991-08-22. PMID:1676928. |
of the 3 major endogenous cortical monoamines whose synaptic reuptake is influenced by cocaine, the actions reported here mimic those described previously for norepinephrine but not those of dopamine or serotonin. |
1991-08-22 |
2023-08-11 |
rat |
| L L Howell, L D Byr. Characterization of the effects of cocaine and GBR 12909, a dopamine uptake inhibitor, on behavior in the squirrel monkey. The Journal of pharmacology and experimental therapeutics. vol 258. issue 1. 1991-08-20. PMID:1677037. |
characterization of the effects of cocaine and gbr 12909, a dopamine uptake inhibitor, on behavior in the squirrel monkey. |
1991-08-20 |
2023-08-11 |
monkey |
| L L Howell, L D Byr. Characterization of the effects of cocaine and GBR 12909, a dopamine uptake inhibitor, on behavior in the squirrel monkey. The Journal of pharmacology and experimental therapeutics. vol 258. issue 1. 1991-08-20. PMID:1677037. |
the behavioral effects of cocaine and gbr 12909, a highly selective dopamine uptake inhibitor, were compared in squirrel monkeys trained to respond under a fixed-interval schedule of stimulus termination and a second-order schedule of drug self-administration. |
1991-08-20 |
2023-08-11 |
monkey |
| L L Howell, L D Byr. Characterization of the effects of cocaine and GBR 12909, a dopamine uptake inhibitor, on behavior in the squirrel monkey. The Journal of pharmacology and experimental therapeutics. vol 258. issue 1. 1991-08-20. PMID:1677037. |
when cocaine and gbr 12909 were studied in combination with dopamine antagonists, the effects of either on fixed-interval performance were attenuated in a similar manner by a d1-selective antagonist (sch 23390) and a d2-selective antagonist (spiperone), indicating the involvement of both d1 and d2 receptor subtypes. |
1991-08-20 |
2023-08-11 |
monkey |