| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Y Wang, J M Yeung, E Friedma. Prenatal cocaine exposure selectively reduces mesocortical dopamine release. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791093. |
prenatal cocaine exposure enhanced the responsiveness to in vitro dopamine in the two cortical regions but not in striatum. |
1995-07-21 |
2023-08-12 |
rabbit |
| H Y Wang, J M Yeung, E Friedma. Prenatal cocaine exposure selectively reduces mesocortical dopamine release. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791093. |
fetal cocaine exposure did not affect the levels of dopamine or its metabolites, 3,4-dihydroxyphenylacetic acid and homovanillic acid, in frontal cortex or striatum. |
1995-07-21 |
2023-08-12 |
rabbit |
| H Y Wang, J M Yeung, E Friedma. Prenatal cocaine exposure selectively reduces mesocortical dopamine release. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791093. |
these findings demonstrate that prenatal cocaine exposure selectively affects depolarization-evoked [3h]dopamine release and its regulation by presynaptic dopamine autoreceptor in cortical areas. |
1995-07-21 |
2023-08-12 |
rabbit |
| L M Gracz, B K Madra. [3H]WIN 35,428 ([3H]CFT) binds to multiple charge-states of the solubilized dopamine transporter in primate striatum. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791095. |
the rank order of potency of these compounds for inhibiting [3h]cft binding (lu 19-005 > mazindol > cft > gbr 12909 > (-)-cocaine > talsupram > dopamine > norepinephrine > citalopram) was consistent with [3h]cft labeling cocaine binding sites on the dopamine transporter. |
1995-07-21 |
2023-08-12 |
monkey |
| L M Gracz, B K Madra. [3H]WIN 35,428 ([3H]CFT) binds to multiple charge-states of the solubilized dopamine transporter in primate striatum. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791095. |
therefore, multiple binding components for cocaine reside solely on the dopamine transporter and exhibit different affinities for drugs depending on the charge-state of the transporter. |
1995-07-21 |
2023-08-12 |
monkey |
| N D Volkow, S J Gatley, J S Fowler, R Chen, J Logan, S L Dewey, Y S Ding, N Pappas, P King, R R MacGrego. Long-lasting inhibition of in vivo cocaine binding to dopamine transporters by 3 beta-(4-iodophenyl)tropane-2-carboxylic acid methyl ester: RTI-55 or beta CIT. Synapse (New York, N.Y.). vol 19. issue 3. 1995-07-18. PMID:7784960. |
long-lasting inhibition of in vivo cocaine binding to dopamine transporters by 3 beta-(4-iodophenyl)tropane-2-carboxylic acid methyl ester: rti-55 or beta cit. |
1995-07-18 |
2023-08-12 |
mouse |
| N D Volkow, S J Gatley, J S Fowler, R Chen, J Logan, S L Dewey, Y S Ding, N Pappas, P King, R R MacGrego. Long-lasting inhibition of in vivo cocaine binding to dopamine transporters by 3 beta-(4-iodophenyl)tropane-2-carboxylic acid methyl ester: RTI-55 or beta CIT. Synapse (New York, N.Y.). vol 19. issue 3. 1995-07-18. PMID:7784960. |
cocaine analogs such as 3 beta-(4-iodophenyl)tropane-2 beta-carboxylic acid methyl ester (rti-55 or beta cit) with a higher affinity for the dopamine transporter (dat) may be potentially useful in interfering with cocaine's actions in brain. |
1995-07-18 |
2023-08-12 |
mouse |
| F J Seidler, S W Temple, E C McCook, T A Slotki. Cocaine inhibits central noradrenergic and dopaminergic activity during the critical developmental period in which catecholamines influence cell development. Brain research. Developmental brain research. vol 85. issue 1. 1995-07-14. PMID:7781166. |
neonatal rats (1, 7, 14 and 21 days old) were given cocaine (30 mg/kg) acutely and the turnover of norepinephrine and dopamine, a measure of synaptic activity, was evaluated in vivo in three different brain regions known to be adversely affected by cocaine. |
1995-07-14 |
2023-08-12 |
rat |
| D Clark, M Exner, L J Furmidge, K Svensson, C Sonesso. Effects of the dopamine autoreceptor antagonist (-)-DS121 on the discriminative stimulus properties of d-amphetamine and cocaine. European journal of pharmacology. vol 275. issue 1. 1995-07-10. PMID:7774664. |
effects of the dopamine autoreceptor antagonist (-)-ds121 on the discriminative stimulus properties of d-amphetamine and cocaine. |
1995-07-10 |
2023-08-12 |
rat |
| C A Schad, J B Justice, S G Holtzma. Naloxone reduces the neurochemical and behavioral effects of amphetamine but not those of cocaine. European journal of pharmacology. vol 275. issue 1. 1995-07-10. PMID:7774666. |
amphetamine and cocaine dose-dependently increased extracellular dopamine in both the nucleus accumbens and striatum. |
1995-07-10 |
2023-08-12 |
rat |
| F Refahi-Lyamani, S Saadouni, J Costentin, J J Bonne. Interaction of two sulfhydryl reagents with a cation recognition site on the neuronal dopamine carrier evidences small differences between [3H]GBR 12783 and [3H]cocaine binding sites. Naunyn-Schmiedeberg's archives of pharmacology. vol 351. issue 2. 1995-07-06. PMID:7770096. |
interaction of two sulfhydryl reagents with a cation recognition site on the neuronal dopamine carrier evidences small differences between [3h]gbr 12783 and [3h]cocaine binding sites. |
1995-07-06 |
2023-08-12 |
rat |
| F Refahi-Lyamani, S Saadouni, J Costentin, J J Bonne. Interaction of two sulfhydryl reagents with a cation recognition site on the neuronal dopamine carrier evidences small differences between [3H]GBR 12783 and [3H]cocaine binding sites. Naunyn-Schmiedeberg's archives of pharmacology. vol 351. issue 2. 1995-07-06. PMID:7770096. |
we have compared the effect of treating rat striatal cell membranes with ionic hydrophilic sulfhydryl reagents on the specific bindings of [3h]cocaine and of [3h]gbr 12783 (1-[2-(diphenylmethoxy)ethyl]4-(3-phenyl-2-[1-3h]propenyl)-piperaz ine) to the neuronal transporter of dopamine. |
1995-07-06 |
2023-08-12 |
rat |
| F Refahi-Lyamani, S Saadouni, J Costentin, J J Bonne. Interaction of two sulfhydryl reagents with a cation recognition site on the neuronal dopamine carrier evidences small differences between [3H]GBR 12783 and [3H]cocaine binding sites. Naunyn-Schmiedeberg's archives of pharmacology. vol 351. issue 2. 1995-07-06. PMID:7770096. |
some of these drugs (100 mumol/l dopamine, 1 mumol/l mazindol or 100 mumol/l cocaine) protected the specific binding of [3h]cocaine against the effects of phmbs, whereas 1 mmol/l p-tyramine, 10 mumol/l nomifensine and 10 nmol/l gbr 12783 were ineffective. |
1995-07-06 |
2023-08-12 |
rat |
| R S Mansbach, S A Jortani, R L Balste. Discriminative stimulus effects of esteratic local anesthetics in squirrel monkeys. European journal of pharmacology. vol 274. issue 1-3. 1995-07-05. PMID:7768269. |
doses of dimethocaine (1.7 mg/kg) and cocaine (0.3 mg/kg) which produced full (> 80%) substitution for cocaine were administered in combination with the dopamine d1 receptor antagonist sch 39166 ((-)-trans-6,7,7a,8,9,13b-hexahydro-3-chloro-2-hydroxy-n-methyl-5h -benzo [d]naphtho-(2,1-b)azepine) and the dopamine d2 receptor antagonist raclopride (both at 0.003-0.03 mg/kg). |
1995-07-05 |
2023-08-12 |
monkey |
| H Sershen, A Hashim, A Lajth. The effect of ibogaine on kappa-opioid- and 5-HT3-induced changes in stimulation-evoked dopamine release in vitro from striatum of C57BL/6By mice. Brain research bulletin. vol 36. issue 6. 1995-06-29. PMID:7757494. |
cocaine (10(-6) m), a dopamine uptake blocker, increased the electrically-evoked release of dopamine; ibogaine pretreatment did not affect the enhanced electrically-induced release of [3h]dopamine by in vitro cocaine. |
1995-06-29 |
2023-08-12 |
mouse |
| S R Jones, P A Garris, C D Kilts, R M Wightma. Comparison of dopamine uptake in the basolateral amygdaloid nucleus, caudate-putamen, and nucleus accumbens of the rat. Journal of neurochemistry. vol 64. issue 6. 1995-06-28. PMID:7760038. |
addition of a dopamine uptake inhibitor, cocaine or nomifensine (10 microm), to the perfusion buffer increased the apparent km value > 25-fold in slices of both the caudate-putamen and nucleus accumbens. |
1995-06-28 |
2023-08-12 |
rat |
| B Ferger, K Kuschinsk. Effects of morphine on EEG in rats and their possible relations to hypo- and hyperkinesia. Psychopharmacology. vol 117. issue 2. 1995-06-22. PMID:7753968. |
it was previously shown in rats that administration of cocaine or d-amphetamine in moderate doses produced alterations in eeg characteristic for activation of d1 dopamine receptors, whereas large doses induced alterations resembling activation of d2 dopamine receptors. |
1995-06-22 |
2023-08-12 |
rat |
| G S Robertson, M Jia. D1 and D2 dopamine receptors differentially increase Fos-like immunoreactivity in accumbal projections to the ventral pallidum and midbrain. Neuroscience. vol 64. issue 4. 1995-06-21. PMID:7753373. |
stimulants such as d-amphetamine and cocaine increase fos-like immunoreactivity by enhancing the activation of d1 dopamine receptors. |
1995-06-21 |
2023-08-12 |
Not clear |
| S E Hemby, T J Martin, C Co, S I Dworkin, J E Smit. The effects of intravenous heroin administration on extracellular nucleus accumbens dopamine concentrations as determined by in vivo microdialysis. The Journal of pharmacology and experimental therapeutics. vol 273. issue 2. 1995-06-19. PMID:7752060. |
in addition to the evidence from selective lesions and receptor antagonists, recent determinations of increased extracellular dopamine concentrations ([da]e) in this structure during cocaine and ethanol self-administration have extended this notion. |
1995-06-19 |
2023-08-12 |
rat |
| S E Hemby, C Co, D Reboussin, H M Davies, S I Dworkin, J E Smit. Comparison of a novel tropane analog of cocaine, 2 beta-propanoyl-3 beta-(4-tolyl) tropane with cocaine HCl in rats: nucleus accumbens extracellular dopamine concentration and motor activity. The Journal of pharmacology and experimental therapeutics. vol 273. issue 2. 1995-06-19. PMID:7752068. |
comparison of a novel tropane analog of cocaine, 2 beta-propanoyl-3 beta-(4-tolyl) tropane with cocaine hcl in rats: nucleus accumbens extracellular dopamine concentration and motor activity. |
1995-06-19 |
2023-08-12 |
rat |