| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Pifl, H Drobny, H Reither, O Hornykiewicz, E A Singe. Mechanism of the dopamine-releasing actions of amphetamine and cocaine: plasmalemmal dopamine transporter versus vesicular monoamine transporter. Molecular pharmacology. vol 47. issue 2. 1995-03-29. PMID:7870046. |
the effects of amphetamine and cocaine were studied in [3h]-dopamine-loaded and superfused cos-7 cells transfected with either the cdna of the plasmalemmal dopamine transporter ("dat cells") or the cdna of the vesicular amine transporter ("vat cells"), or with both transporters ("dat/vat cells"). |
1995-03-29 |
2023-08-12 |
Not clear |
| C Pifl, H Drobny, H Reither, O Hornykiewicz, E A Singe. Mechanism of the dopamine-releasing actions of amphetamine and cocaine: plasmalemmal dopamine transporter versus vesicular monoamine transporter. Molecular pharmacology. vol 47. issue 2. 1995-03-29. PMID:7870046. |
cocaine (up to 100 microm) did not exert any effect of its own in dat cells or vat cells but inhibited the amphetamine-induced release of dopamine from dat cells in a competitive manner. |
1995-03-29 |
2023-08-12 |
Not clear |
| C Pifl, H Drobny, H Reither, O Hornykiewicz, E A Singe. Mechanism of the dopamine-releasing actions of amphetamine and cocaine: plasmalemmal dopamine transporter versus vesicular monoamine transporter. Molecular pharmacology. vol 47. issue 2. 1995-03-29. PMID:7870046. |
in dat/vat cells cocaine and its analogue (-)-2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane caused an efflux of dopamine resembling that caused by amphetamine but quantitatively much smaller. |
1995-03-29 |
2023-08-12 |
Not clear |
| C Pifl, H Drobny, H Reither, O Hornykiewicz, E A Singe. Mechanism of the dopamine-releasing actions of amphetamine and cocaine: plasmalemmal dopamine transporter versus vesicular monoamine transporter. Molecular pharmacology. vol 47. issue 2. 1995-03-29. PMID:7870046. |
the releasing action of cocaine is dependent on the existence of a vesicular pool of the neurotransmitter and seems to be linked to inhibition of the plasmalemmal dopamine transporter. |
1995-03-29 |
2023-08-12 |
Not clear |
| J L Evenden, M Turpin, L Oliver, C Jenning. Caffeine and nicotine improve visual tracking by rats: a comparison with amphetamine, cocaine and apomorphine. Psychopharmacology. vol 110. issue 1-2. 1995-03-29. PMID:7870879. |
the present study was undertaken to determine whether these performance enhancing effects of amphetamine could also be obtained with cocaine and apomorphine, which both have psychomotor stimulant effects through their actions as, respectively, indirect and direct dopamine agonists, and by caffeine and nicotine, which do not have a direct dopaminergic mechanism of action. |
1995-03-29 |
2023-08-12 |
rat |
| G R King, C Kuhn, E H Ellinwoo. Dopamine efflux during withdrawal from continuous or intermittent cocaine. Psychopharmacology. vol 111. issue 2. 1995-03-29. PMID:7870949. |
dopamine efflux during withdrawal from continuous or intermittent cocaine. |
1995-03-29 |
2023-08-12 |
human |
| G R King, C Kuhn, E H Ellinwoo. Dopamine efflux during withdrawal from continuous or intermittent cocaine. Psychopharmacology. vol 111. issue 2. 1995-03-29. PMID:7870949. |
the present experiments examined whether these behavioral differences are related to differences in the ability of cocaine to increase extracellular dopamine. |
1995-03-29 |
2023-08-12 |
human |
| G R King, C Kuhn, E H Ellinwoo. Dopamine efflux during withdrawal from continuous or intermittent cocaine. Psychopharmacology. vol 111. issue 2. 1995-03-29. PMID:7870949. |
such changes in dopamine release may be related to the withdrawal symptoms experienced by human cocaine abusers. |
1995-03-29 |
2023-08-12 |
human |
| R D Spealma. Modification of behavioral effects of cocaine by selective serotonin and dopamine uptake inhibitors in squirrel monkeys. Psychopharmacology. vol 112. issue 1. 1995-03-29. PMID:7871015. |
modification of behavioral effects of cocaine by selective serotonin and dopamine uptake inhibitors in squirrel monkeys. |
1995-03-29 |
2023-08-12 |
monkey |
| R D Spealma. Modification of behavioral effects of cocaine by selective serotonin and dopamine uptake inhibitors in squirrel monkeys. Psychopharmacology. vol 112. issue 1. 1995-03-29. PMID:7871015. |
modification of the behavioral effects of cocaine by the selective serotonin (5-ht) uptake inhibitors citalopram and fluoxetine and the selective dopamine (da) uptake inhibitor gbr 12909 was investigated in squirrel monkeys trained under a fixed-interval schedule of reinforcement or a two-lever cocaine-discrimination procedure. |
1995-03-29 |
2023-08-12 |
monkey |
| J S Meyer, L P Shearman, L M Collins, R L Maguir. Cocaine binding sites in fetal rat brain: implications for prenatal cocaine action. Psychopharmacology. vol 112. issue 4. 1995-03-29. PMID:7871055. |
various monoamine uptake inhibitors displaced labeled cocaine with potencies consistent with the idea that [3h]cocaine labels the dopamine (da), serotonin (5-ht), and possibly also the norepinephrine (ne) transporters in whole fetal brain preparations. |
1995-03-29 |
2023-08-12 |
rat |
| M E Benwell, D J Balfour, H M Lucch. Influence of tetrodotoxin and calcium on changes in extracellular dopamine levels evoked by systemic nicotine. Psychopharmacology. vol 112. issue 4. 1995-03-29. PMID:7871059. |
the influence of tetrodotoxin (ttx) and calcium on the increase of extracellular dopamine (da) levels in the nucleus accumbens (nacc), evoked by the systemic administration of nicotine, cocaine and d-amphetamine, have been studied in conscious, freely moving rats using in vivo microdialysis. |
1995-03-29 |
2023-08-12 |
rat |
| S Schenk, A Valadez, C McNamara, D T House, D Higley, M G Bankson, S Gibbs, B A Horge. Development and expression of sensitization to cocaine's reinforcing properties: role of NMDA receptors. Psychopharmacology. vol 111. issue 3. 1995-03-28. PMID:7870971. |
these data suggest that the nmda receptor, possibly through interactions with dopamine systems, is critical for both the development and expression of sensitization to cocaine's reinforcing effects produced by intermittent preexposures to amphetamine. |
1995-03-28 |
2023-08-12 |
rat |
| S Rosenzweig-Lipson, P Hesterberg, J Bergma. Observational studies of dopamine D1 and D2 agonists in squirrel monkeys. Psychopharmacology. vol 116. issue 1. 1995-03-23. PMID:7862937. |
the indirect dopamine agonists cocaine, gbr 12909, and d-amphetamine and the nonselective d1/d2 agonist cy 208-243, but not (-)apomorphine, had effects comparable to those of d1 agonists such as skf 81297. |
1995-03-23 |
2023-08-12 |
monkey |
| S Rosenzweig-Lipson, P Hesterberg, J Bergma. Observational studies of dopamine D1 and D2 agonists in squirrel monkeys. Psychopharmacology. vol 116. issue 1. 1995-03-23. PMID:7862937. |
additionally, effects of the d1 agonist skf 82958 and the indirect dopamine agonist cocaine were surmountably antagonized by the d1 antagonist sch 39166. |
1995-03-23 |
2023-08-12 |
monkey |
| M R Weed, K E Vanover, W L Woolverto. Reinforcing effect of the D1 dopamine agonist SKF 81297 in rhesus monkeys. Psychopharmacology. vol 113. issue 1. 1995-03-20. PMID:7862828. |
when responding was stable, saline or the d1 dopamine agonist skf 81297 (skf; 0.001-0.3 mg/kg/inj) was substituted for cocaine. |
1995-03-20 |
2023-08-12 |
monkey |
| L Pulvirenti, D Smith, G F Koo. SDZ 208-911, an amino-ergoline with partial dopamine agonist properties, dose dependently increases cocaine self-administration in the rat. Psychopharmacology. vol 113. issue 3-4. 1995-03-20. PMID:7862868. |
sdz 208-911, an amino-ergoline with partial dopamine agonist properties, dose dependently increases cocaine self-administration in the rat. |
1995-03-20 |
2023-08-12 |
rat |
| L Pulvirenti, D Smith, G F Koo. SDZ 208-911, an amino-ergoline with partial dopamine agonist properties, dose dependently increases cocaine self-administration in the rat. Psychopharmacology. vol 113. issue 3-4. 1995-03-20. PMID:7862868. |
brain dopamine neurotransmission appears to be an important component of the neural pathways involved in the maintenance of intravenous (iv) cocaine self-administration in rats. |
1995-03-20 |
2023-08-12 |
rat |
| L Pulvirenti, D Smith, G F Koo. SDZ 208-911, an amino-ergoline with partial dopamine agonist properties, dose dependently increases cocaine self-administration in the rat. Psychopharmacology. vol 113. issue 3-4. 1995-03-20. PMID:7862868. |
the effects of a novel partial dopamine agonist, sdz 208-911, on intravenous cocaine self-administration in rats was studied. |
1995-03-20 |
2023-08-12 |
rat |
| P M Callahan, R De La Garza, K A Cunningha. Discriminative stimulus properties of cocaine: modulation by dopamine D1 receptors in the nucleus accumbens. Psychopharmacology. vol 115. issue 1-2. 1995-03-20. PMID:7862881. |
discriminative stimulus properties of cocaine: modulation by dopamine d1 receptors in the nucleus accumbens. |
1995-03-20 |
2023-08-12 |
rat |