| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M A Klitenick, C S Tham, H C Fibige. Cocaine and d-amphetamine increase c-fos expression in the rat cerebellum. Synapse (New York, N.Y.). vol 19. issue 1. 1995-05-09. PMID:7709341. |
systemic administration of d-amphetamine (1.5, 6 mg/kg) or cocaine (10, 20 mg/kg) increased locomotor activity, which at low doses was blocked by pretreatment with the dopamine d1 receptor antagonist sch 23390 (1 mg/kg). |
1995-05-09 |
2023-08-12 |
rat |
| C Héron, J Costentin, J J Bonne. Evidence that pure uptake inhibitors including cocaine interact slowly with the dopamine neuronal carrier. European journal of pharmacology. vol 264. issue 3. 1995-04-28. PMID:7698180. |
evidence that pure uptake inhibitors including cocaine interact slowly with the dopamine neuronal carrier. |
1995-04-28 |
2023-08-12 |
rat |
| I M Maisonneuve, S Archer, S D Glic. U50,488, a kappa opioid receptor agonist, attenuates cocaine-induced increases in extracellular dopamine in the nucleus accumbens of rats. Neuroscience letters. vol 181. issue 1-2. 1995-04-27. PMID:7898771. |
), which alone caused a modest decrease in dopamine levels, produced a 50% decrease in the effect of cocaine on dopamine levels. |
1995-04-27 |
2023-08-12 |
rat |
| O Edvardsen, S G Dah. A putative model of the dopamine transporter. Brain research. Molecular brain research. vol 27. issue 2. 1995-04-25. PMID:7898310. |
the model suggests specific binding sites for dopamine and cocaine, a functional role for chloride ions, and accounts for known structure-activity relationships of cocaine analogs at the dopamine transporter. |
1995-04-25 |
2023-08-12 |
human |
| F Karoum, S J Chrapusta, R Brinjak, A Hitri, R J Wyat. Regional effects of amphetamine, cocaine, nomifensine and GBR 12909 on the dynamics of dopamine release and metabolism in the rat brain. British journal of pharmacology. vol 113. issue 4. 1995-04-19. PMID:7889297. |
regional effects of amphetamine, cocaine, nomifensine and gbr 12909 on the dynamics of dopamine release and metabolism in the rat brain. |
1995-04-19 |
2023-08-12 |
rat |
| F Karoum, S J Chrapusta, R Brinjak, A Hitri, R J Wyat. Regional effects of amphetamine, cocaine, nomifensine and GBR 12909 on the dynamics of dopamine release and metabolism in the rat brain. British journal of pharmacology. vol 113. issue 4. 1995-04-19. PMID:7889297. |
the effects of single-dose regimens of amphetamine, cocaine, nomifensine and gbr 12909 on the dynamics of dopamine (da) release and metabolism were evaluated in the frontal cortex, hypothalamus, nucleus accumbens and striatum. |
1995-04-19 |
2023-08-12 |
rat |
| B A Bennett, C H Wichems, C K Hollingsworth, H M Davies, C Thornley, T Sexton, S R Childer. Novel 2-substituted cocaine analogs: uptake and ligand binding studies at dopamine, serotonin and norepinephrine transport sites in the rat brain. The Journal of pharmacology and experimental therapeutics. vol 272. issue 3. 1995-04-14. PMID:7891330. |
novel 2-substituted cocaine analogs: uptake and ligand binding studies at dopamine, serotonin and norepinephrine transport sites in the rat brain. |
1995-04-14 |
2023-08-12 |
rat |
| M E Wolf, C J Xue, F J White, S L Dahli. MK-801 does not prevent acute stimulatory effects of amphetamine or cocaine on locomotor activity or extracellular dopamine levels in rat nucleus accumbens. Brain research. vol 666. issue 2. 1995-04-13. PMID:7882032. |
mk-801 does not prevent acute stimulatory effects of amphetamine or cocaine on locomotor activity or extracellular dopamine levels in rat nucleus accumbens. |
1995-04-13 |
2023-08-12 |
rat |
| M E Wolf, C J Xue, F J White, S L Dahli. MK-801 does not prevent acute stimulatory effects of amphetamine or cocaine on locomotor activity or extracellular dopamine levels in rat nucleus accumbens. Brain research. vol 666. issue 2. 1995-04-13. PMID:7882032. |
to examine this issue, behavioral and microdialysis studies assessed the effect of pretreatment with 0.1 mg/kg mk-801 on the ability of amphetamine and cocaine to stimulate locomotor activity and elevate extracellular dopamine (da) levels in nucleus accumbens; this dose of mk-801 prevents sensitization when coadministered repeatedly with these stimulants. |
1995-04-13 |
2023-08-12 |
rat |
| Y Zea-Ponce, R M Baldwin, M Laruelle, S Wang, J L Neumeyer, R B Inni. Simplified multidose preparation of iodine-123-beta-CIT: a marker for dopamine transporters. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 36. issue 3. 1995-04-07. PMID:7884521. |
iodine-123-beta-cit is a spect radioligand for dopamine and 5-ht transporters with potential use in parkinson's disease, schizophrenia and cocaine addiction studies. |
1995-04-07 |
2023-08-12 |
Not clear |
| A Keys, G Elliso. Continuous cocaine induces persisting alterations in dopamine overflow in caudate following perfusion with a D1 agonist. Journal of neural transmission. General section. vol 97. issue 3. 1995-04-03. PMID:7532953. |
continuous cocaine induces persisting alterations in dopamine overflow in caudate following perfusion with a d1 agonist. |
1995-04-03 |
2023-08-12 |
rat |
| A Keys, G Elliso. Continuous cocaine induces persisting alterations in dopamine overflow in caudate following perfusion with a D1 agonist. Journal of neural transmission. General section. vol 97. issue 3. 1995-04-03. PMID:7532953. |
the present study examined whether exposure to 5 days of continuous cocaine in rats would produce any persisting alterations of the decrease in striatal dopamine (da) overflow produced by local infusion of a d1 receptor agonist. |
1995-04-03 |
2023-08-12 |
rat |
| J Gelernter, H R Kranzler, S L Satel, P A Ra. Genetic association between dopamine transporter protein alleles and cocaine-induced paranoia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 11. issue 3. 1995-03-29. PMID:7865100. |
cocaine blocks the dopamine transporter and increases synaptic availability of dopamine. |
1995-03-29 |
2023-08-12 |
Not clear |
| C Pifl, H Drobny, H Reither, O Hornykiewicz, E A Singe. Mechanism of the dopamine-releasing actions of amphetamine and cocaine: plasmalemmal dopamine transporter versus vesicular monoamine transporter. Molecular pharmacology. vol 47. issue 2. 1995-03-29. PMID:7870046. |
mechanism of the dopamine-releasing actions of amphetamine and cocaine: plasmalemmal dopamine transporter versus vesicular monoamine transporter. |
1995-03-29 |
2023-08-12 |
Not clear |
| C Pifl, H Drobny, H Reither, O Hornykiewicz, E A Singe. Mechanism of the dopamine-releasing actions of amphetamine and cocaine: plasmalemmal dopamine transporter versus vesicular monoamine transporter. Molecular pharmacology. vol 47. issue 2. 1995-03-29. PMID:7870046. |
the effects of amphetamine and cocaine were studied in [3h]-dopamine-loaded and superfused cos-7 cells transfected with either the cdna of the plasmalemmal dopamine transporter ("dat cells") or the cdna of the vesicular amine transporter ("vat cells"), or with both transporters ("dat/vat cells"). |
1995-03-29 |
2023-08-12 |
Not clear |
| C Pifl, H Drobny, H Reither, O Hornykiewicz, E A Singe. Mechanism of the dopamine-releasing actions of amphetamine and cocaine: plasmalemmal dopamine transporter versus vesicular monoamine transporter. Molecular pharmacology. vol 47. issue 2. 1995-03-29. PMID:7870046. |
cocaine (up to 100 microm) did not exert any effect of its own in dat cells or vat cells but inhibited the amphetamine-induced release of dopamine from dat cells in a competitive manner. |
1995-03-29 |
2023-08-12 |
Not clear |
| C Pifl, H Drobny, H Reither, O Hornykiewicz, E A Singe. Mechanism of the dopamine-releasing actions of amphetamine and cocaine: plasmalemmal dopamine transporter versus vesicular monoamine transporter. Molecular pharmacology. vol 47. issue 2. 1995-03-29. PMID:7870046. |
in dat/vat cells cocaine and its analogue (-)-2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane caused an efflux of dopamine resembling that caused by amphetamine but quantitatively much smaller. |
1995-03-29 |
2023-08-12 |
Not clear |
| C Pifl, H Drobny, H Reither, O Hornykiewicz, E A Singe. Mechanism of the dopamine-releasing actions of amphetamine and cocaine: plasmalemmal dopamine transporter versus vesicular monoamine transporter. Molecular pharmacology. vol 47. issue 2. 1995-03-29. PMID:7870046. |
the releasing action of cocaine is dependent on the existence of a vesicular pool of the neurotransmitter and seems to be linked to inhibition of the plasmalemmal dopamine transporter. |
1995-03-29 |
2023-08-12 |
Not clear |
| J L Evenden, M Turpin, L Oliver, C Jenning. Caffeine and nicotine improve visual tracking by rats: a comparison with amphetamine, cocaine and apomorphine. Psychopharmacology. vol 110. issue 1-2. 1995-03-29. PMID:7870879. |
the present study was undertaken to determine whether these performance enhancing effects of amphetamine could also be obtained with cocaine and apomorphine, which both have psychomotor stimulant effects through their actions as, respectively, indirect and direct dopamine agonists, and by caffeine and nicotine, which do not have a direct dopaminergic mechanism of action. |
1995-03-29 |
2023-08-12 |
rat |
| G R King, C Kuhn, E H Ellinwoo. Dopamine efflux during withdrawal from continuous or intermittent cocaine. Psychopharmacology. vol 111. issue 2. 1995-03-29. PMID:7870949. |
dopamine efflux during withdrawal from continuous or intermittent cocaine. |
1995-03-29 |
2023-08-12 |
human |