| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Karler, L D Calder, L H Thai, J B Bedingfiel. The dopaminergic, glutamatergic, GABAergic bases for the action of amphetamine and cocaine. Brain research. vol 671. issue 1. 1995-06-01. PMID:7728520. |
the present experiments were designed to evaluate pharmacologically the role of three neuroanatomically related systems--dopamine, glutamate and gaba--in the motor-stimulant response to amphetamine and cocaine. |
1995-06-01 |
2023-08-12 |
Not clear |
| A Eshleman, C Dunigan, A Shamoo, M Eldefraw. ATP enhances catecholamine uptake into PC12 cells. Life sciences. vol 56. issue 19. 1995-05-25. PMID:7723590. |
it is suggested that atp is an allosteric modulator of the transporter and that a stable atp analog, with atp-like enhancement of dopamine uptake, may be an effective cocaine antagonist. |
1995-05-25 |
2023-08-12 |
Not clear |
| S Vanhatalo, S Soinil. Pharmacological characterization of serotonin synthesis and uptake suggest a false transmitter role for serotonin in the pituitary intermediate lobe. Neuroscience research. vol 21. issue 2. 1995-05-23. PMID:7724065. |
however, cocaine (10(-5)-10(-6) m) blocked serotonin uptake into these terminals, suggesting that serotonin uptake occurs through a dopamine transporter. |
1995-05-23 |
2023-08-12 |
rat |
| J W Boja, J L Cadet, T A Kopajtic, J Lever, H H Seltzman, C D Wyrick, A H Lewin, P Abraham, F I Carrol. Selective labeling of the dopamine transporter by the high affinity ligand 3 beta-(4-[125I]iodophenyl)tropane-2 beta-carboxylic acid isopropyl ester. Molecular pharmacology. vol 47. issue 4. 1995-05-19. PMID:7723739. |
the iodine-125 analog of the dopaminergically selective cocaine analog 3 beta-(4-iodophenyl)tropane-2 beta-carboxylic acid isopropyl ester (rt1-121) was evaluated as a probe for the dopamine transporter in rat striatum. |
1995-05-19 |
2023-08-12 |
rat |
| E A Kiyatkin, E A Stei. Fluctuations in nucleus accumbens dopamine during cocaine self-administration behavior: an in vivo electrochemical study. Neuroscience. vol 64. issue 3. 1995-05-18. PMID:7715774. |
fluctuations in nucleus accumbens dopamine during cocaine self-administration behavior: an in vivo electrochemical study. |
1995-05-18 |
2023-08-12 |
rat |
| E A Kiyatkin, E A Stei. Fluctuations in nucleus accumbens dopamine during cocaine self-administration behavior: an in vivo electrochemical study. Neuroscience. vol 64. issue 3. 1995-05-18. PMID:7715774. |
high-speed chronoamperometry with nafion-coated monoamine-sensitive carbon fiber electrodes was used to estimate changes in extracellular dopamine concentration in the nucleus accumbens during cocaine self-administration behavior in rats. |
1995-05-18 |
2023-08-12 |
rat |
| E A Kiyatkin, E A Stei. Fluctuations in nucleus accumbens dopamine during cocaine self-administration behavior: an in vivo electrochemical study. Neuroscience. vol 64. issue 3. 1995-05-18. PMID:7715774. |
signal decreases seen after self-administered procaine suggest that cocaine's local anesthetic action may contribute to this decrease in dopamine release. |
1995-05-18 |
2023-08-12 |
rat |
| H Y Wang, S Runyan, E Yadin, E Friedma. Prenatal exposure to cocaine selectively reduces D1 dopamine receptor-mediated activation of striatal Gs proteins. The Journal of pharmacology and experimental therapeutics. vol 273. issue 1. 1995-05-17. PMID:7714804. |
prenatal exposure to cocaine selectively reduces d1 dopamine receptor-mediated activation of striatal gs proteins. |
1995-05-17 |
2023-08-12 |
Not clear |
| H Y Wang, S Runyan, E Yadin, E Friedma. Prenatal exposure to cocaine selectively reduces D1 dopamine receptor-mediated activation of striatal Gs proteins. The Journal of pharmacology and experimental therapeutics. vol 273. issue 1. 1995-05-17. PMID:7714804. |
the effect of in utero exposure to cocaine on striatal dopamine receptors was assessed at postnatal days 10 through 100 by examining receptor-mediated increases in gtp binding to g alpha proteins. |
1995-05-17 |
2023-08-12 |
Not clear |
| H Y Wang, S Runyan, E Yadin, E Friedma. Prenatal exposure to cocaine selectively reduces D1 dopamine receptor-mediated activation of striatal Gs proteins. The Journal of pharmacology and experimental therapeutics. vol 273. issue 1. 1995-05-17. PMID:7714804. |
moreover, prenatal cocaine did not affect [3h]sch23390 binding to d1 dopamine receptors in the caudate, putamen or substantia nigra. |
1995-05-17 |
2023-08-12 |
Not clear |
| E Tirelli, J M Witki. Differential effects of direct and indirect dopamine agonists on the induction of gnawing in C57Bl/6J mice. The Journal of pharmacology and experimental therapeutics. vol 273. issue 1. 1995-05-17. PMID:7714815. |
indirect dopamine agonists, including dopamine releasers such as fencamfamine, (+)-amphetamine and amfenolic acid and dopamine uptake inhibitors such as cocaine, gbr 12909 (1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-[3- phenylpropyl]piperazine dihcl) and nomifensine produced dose-dependent increases in gnawing. |
1995-05-17 |
2023-08-12 |
mouse |
| E Tirelli, J M Witki. Differential effects of direct and indirect dopamine agonists on the induction of gnawing in C57Bl/6J mice. The Journal of pharmacology and experimental therapeutics. vol 273. issue 1. 1995-05-17. PMID:7714815. |
in addition, both the dopamine d1 antagonist sch 23390 [r-(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro- 1h-3-benzazepine], the d2 antagonist eticlopride and the dopamine d1/d2 antagonist flupenthixol produced dose-dependent blockade of gnawing induced by either cocaine or methylphenidate. |
1995-05-17 |
2023-08-12 |
mouse |
| D M Camp, K E Browman, T E Robinso. The effects of methamphetamine and cocaine on motor behavior and extracellular dopamine in the ventral striatum of Lewis versus Fischer 344 rats. Brain research. vol 668. issue 1-2. 1995-05-10. PMID:7704604. |
the effects of methamphetamine and cocaine on motor behavior and extracellular dopamine in the ventral striatum of lewis versus fischer 344 rats. |
1995-05-10 |
2023-08-12 |
rat |
| D M Camp, K E Browman, T E Robinso. The effects of methamphetamine and cocaine on motor behavior and extracellular dopamine in the ventral striatum of Lewis versus Fischer 344 rats. Brain research. vol 668. issue 1-2. 1995-05-10. PMID:7704604. |
the effects of an acute systemic injection of methamphetamine (mamp) or cocaine (coc) on motor behavior (stereotypy, locomotor activity, and rearing) and extracellular dopamine (da) in the ventral striatum were compared in lewis (lew) versus fischer 344 (f344) rats, using in vivo microdialysis in awake freely moving animals. |
1995-05-10 |
2023-08-12 |
rat |
| J M Wilson, J N Nobrega, W A Corrigall, K M Coen, K Shannak, S J Kis. Amygdala dopamine levels are markedly elevated after self- but not passive-administration of cocaine. Brain research. vol 668. issue 1-2. 1995-05-10. PMID:7704616. |
amygdala dopamine levels are markedly elevated after self- but not passive-administration of cocaine. |
1995-05-10 |
2023-08-12 |
rat |
| J M Wilson, J N Nobrega, W A Corrigall, K M Coen, K Shannak, S J Kis. Amygdala dopamine levels are markedly elevated after self- but not passive-administration of cocaine. Brain research. vol 668. issue 1-2. 1995-05-10. PMID:7704616. |
the influence of cocaine on rat brain monoaminergic neurotransmitters (dopamine, serotonin, noradrenaline) and their metabolites, and on binding of [3h]win 35,428 and [3h]gbr 12,935 to the dopamine transporter was measured after 4 weeks of cocaine exposure. |
1995-05-10 |
2023-08-12 |
rat |
| J M Wilson, J N Nobrega, W A Corrigall, K M Coen, K Shannak, S J Kis. Amygdala dopamine levels are markedly elevated after self- but not passive-administration of cocaine. Brain research. vol 668. issue 1-2. 1995-05-10. PMID:7704616. |
as compared with the controls, mean dopamine and serotonin levels were significantly elevated (+ 107% and + 47%, respectively) in amygdala of responders, but not of yoked rats, sacrificed 1 h after the last cocaine session. |
1995-05-10 |
2023-08-12 |
rat |
| J M Wilson, J N Nobrega, W A Corrigall, K M Coen, K Shannak, S J Kis. Amygdala dopamine levels are markedly elevated after self- but not passive-administration of cocaine. Brain research. vol 668. issue 1-2. 1995-05-10. PMID:7704616. |
dopamine and metabolite levels were normal in all other brain areas examined, including striatum, nucleus accumbens and medial prefrontal cortex, at both 1 h and 4 weeks withdrawal from cocaine. |
1995-05-10 |
2023-08-12 |
rat |
| J D Stekete. Intra-A10 injection of H7 blocks the development of sensitization to cocaine. Neuroreport. vol 6. issue 1. 1995-05-09. PMID:7703432. |
the role of protein kinase activity in the development of behavioral sensitization was examined by injecting the protein kinase inhibitor h7 into the a10 dopamine region 5 min before each of four daily peripheral injections of cocaine. |
1995-05-09 |
2023-08-12 |
Not clear |
| J D Stekete. Intra-A10 injection of H7 blocks the development of sensitization to cocaine. Neuroreport. vol 6. issue 1. 1995-05-09. PMID:7703432. |
these data suggest that increased protein kinase activity in the a10 dopamine region may be important in the development of behavioral sensitization to cocaine. |
1995-05-09 |
2023-08-12 |
Not clear |