| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K M Kantak, M A Edwards, R D Spealma. Effects of N-methyl-D-aspartate antagonists in rats discriminating different doses of cocaine: comparison with direct and indirect dopamine agonists. The Journal of pharmacology and experimental therapeutics. vol 274. issue 2. 1995-09-08. PMID:7636725. |
dose-response functions for selected n-methyl-d-aspartate (nmda) antagonists and direct and indirect dopamine agonists were compared in rats trained to discriminate either a low (2 mg/kg) or a high (10 mg/kg) dose of cocaine from vehicle. |
1995-09-08 |
2023-08-12 |
human |
| K M Kantak, M A Edwards, R D Spealma. Effects of N-methyl-D-aspartate antagonists in rats discriminating different doses of cocaine: comparison with direct and indirect dopamine agonists. The Journal of pharmacology and experimental therapeutics. vol 274. issue 2. 1995-09-08. PMID:7636725. |
the results show that change in the training dose of cocaine can affect both the shape and position of the dose-response functions for representative nmda-associated ion channel blockers and direct and indirect dopamine agonists. |
1995-09-08 |
2023-08-12 |
human |
| R C Pierce, P Duffy, P W Kaliva. Sensitization to cocaine and dopamine autoreceptor subsensitivity in the nucleus accumbens. Synapse (New York, N.Y.). vol 20. issue 1. 1995-08-31. PMID:7624827. |
sensitization to cocaine and dopamine autoreceptor subsensitivity in the nucleus accumbens. |
1995-08-31 |
2023-08-12 |
rat |
| R C Pierce, P Duffy, P W Kaliva. Sensitization to cocaine and dopamine autoreceptor subsensitivity in the nucleus accumbens. Synapse (New York, N.Y.). vol 20. issue 1. 1995-08-31. PMID:7624827. |
in order to evaluate this hypothesis, we administered cocaine to rats daily (15 mg/kg ip x 2 days, 30 mg/kg ip x 5 days) and then monitored nucleus accumbens dopamine during the local administration (through the dialysis probe) of the d2/d3 agonist, quinpirole (0, 0.1, 1, and 10 microm). |
1995-08-31 |
2023-08-12 |
rat |
| R C Pierce, P Duffy, P W Kaliva. Sensitization to cocaine and dopamine autoreceptor subsensitivity in the nucleus accumbens. Synapse (New York, N.Y.). vol 20. issue 1. 1995-08-31. PMID:7624827. |
our results indicate that, relative to saline-pretreated control animals, repeated cocaine administration impaired the ability of quinpirole to decrease extracellular dopamine 1-2 days after the last drug injection. |
1995-08-31 |
2023-08-12 |
rat |
| R C Pierce, P Duffy, P W Kaliva. Sensitization to cocaine and dopamine autoreceptor subsensitivity in the nucleus accumbens. Synapse (New York, N.Y.). vol 20. issue 1. 1995-08-31. PMID:7624827. |
these results demonstrate that repeated cocaine produces a short duration functional tolerance in the capacity of autoreceptor stimulation to inhibit accumbal dopamine release. |
1995-08-31 |
2023-08-12 |
rat |
| D Shi, O Nikodijević, K A Jacobson, J W Dal. Effects of chronic caffeine on adenosine, dopamine and acetylcholine systems in mice. Archives internationales de pharmacodynamie et de therapie. vol 328. issue 3. 1995-08-31. PMID:7625882. |
there is no change in the levels of striatal nicotinic receptors of d2-dopamine receptors, nor of [3h]cocaine binding to dopamine uptake sites. |
1995-08-31 |
2023-08-12 |
mouse |
| J E Williams, W Wieczorek, P Willner, Z L Kru. Parametric analysis of the effects of cocaine and cocaine pretreatment on dopamine release in the nucleus accumbens measured by fast cyclic voltammetry. Brain research. vol 678. issue 1-2. 1995-08-30. PMID:7620892. |
parametric analysis of the effects of cocaine and cocaine pretreatment on dopamine release in the nucleus accumbens measured by fast cyclic voltammetry. |
1995-08-30 |
2023-08-12 |
rat |
| P W Kalivas, P Duff. D1 receptors modulate glutamate transmission in the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 7 Pt 2. 1995-08-30. PMID:7623160. |
these data indicate that the stimulation of d1 receptors in the ventral tegmental area increases the release of glutamate and that increasing extracellular levels of somatodendritic dopamine by systemic cocaine can mimic this effect. |
1995-08-30 |
2023-08-12 |
Not clear |
| I M White, J R Christensen, G S Flory, D W Miller, G V Rebe. Amphetamine, cocaine, and dizocilpine enhance performance on a lever-release, conditioned avoidance response task in rats. Psychopharmacology. vol 118. issue 3. 1995-08-23. PMID:7617826. |
the indirect dopamine agonists, d-amphetamine (0.1 and 0.25 mg/kg) and cocaine (7.5 and 15 mg/kg), enhanced performance on this task. |
1995-08-23 |
2023-08-12 |
rat |
| W M Meil, J M Roll, J W Grimm, A M Lynch, R E Se. Tolerance-like attenuation to contingent and noncontingent cocaine-induced elevation of extracellular dopamine in the ventral striatum following 7 days of withdrawal from chronic treatment. Psychopharmacology. vol 118. issue 3. 1995-08-23. PMID:7617827. |
time-dependent changes in mesolimbic dopamine (da) function are believed to play a role in behavioral sensitization and drug craving experienced during withdrawal from chronic cocaine administration. |
1995-08-23 |
2023-08-12 |
rat |
| A Pap, C W Bradberr. Excitatory amino acid antagonists attenuate the effects of cocaine on extracellular dopamine in the nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 274. issue 1. 1995-08-18. PMID:7616389. |
excitatory amino acid antagonists attenuate the effects of cocaine on extracellular dopamine in the nucleus accumbens. |
1995-08-18 |
2023-08-12 |
Not clear |
| A Pap, C W Bradberr. Excitatory amino acid antagonists attenuate the effects of cocaine on extracellular dopamine in the nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 274. issue 1. 1995-08-18. PMID:7616389. |
the local infusion of 2-amino-5-phosphonovalerate (500 microm), dizocilpine (50 microm) and cnqx (100 microm), started 80 min before cocaine injection, significantly inhibited the cocaine-induced increase in extracellular dopamine. |
1995-08-18 |
2023-08-12 |
Not clear |
| A Pap, C W Bradberr. Excitatory amino acid antagonists attenuate the effects of cocaine on extracellular dopamine in the nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 274. issue 1. 1995-08-18. PMID:7616389. |
our results suggest that both n-methyl-daspartate and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate subtypes of excitatory amino acid antagonist receptors may contribute to the stimulatory effect of cocaine on extracellular dopamine in the nucleus accumbens. |
1995-08-18 |
2023-08-12 |
Not clear |
| S M Florin, R Kuczenski, D S Sega. Effects of reserpine on extracellular caudate dopamine and hippocampus norepinephrine responses to amphetamine and cocaine: mechanistic and behavioral considerations. The Journal of pharmacology and experimental therapeutics. vol 274. issue 1. 1995-08-18. PMID:7616403. |
effects of reserpine on extracellular caudate dopamine and hippocampus norepinephrine responses to amphetamine and cocaine: mechanistic and behavioral considerations. |
1995-08-18 |
2023-08-12 |
rat |
| S M Florin, R Kuczenski, D S Sega. Effects of reserpine on extracellular caudate dopamine and hippocampus norepinephrine responses to amphetamine and cocaine: mechanistic and behavioral considerations. The Journal of pharmacology and experimental therapeutics. vol 274. issue 1. 1995-08-18. PMID:7616403. |
following reserpine pretreatment to disrupt vesicular stores of dopamine and norepinephrine, in vivo microdialysis was used in behaving rats to evaluate the role of vesicles in the neurochemical and behavioral responses to amphetamine and cocaine. |
1995-08-18 |
2023-08-12 |
rat |
| S M Florin, R Kuczenski, D S Sega. Effects of reserpine on extracellular caudate dopamine and hippocampus norepinephrine responses to amphetamine and cocaine: mechanistic and behavioral considerations. The Journal of pharmacology and experimental therapeutics. vol 274. issue 1. 1995-08-18. PMID:7616403. |
likewise, reserpine almost completely abolished the caudate putamen dopamine response to cocaine. |
1995-08-18 |
2023-08-12 |
rat |
| S M Florin, R Kuczenski, D S Sega. Effects of reserpine on extracellular caudate dopamine and hippocampus norepinephrine responses to amphetamine and cocaine: mechanistic and behavioral considerations. The Journal of pharmacology and experimental therapeutics. vol 274. issue 1. 1995-08-18. PMID:7616403. |
concomitant behavioral assessments revealed that the behavioral responses to cocaine and the lowest dose of amphetamine, like the dopamine responses, were significantly suppressed by reserpine pretreatment. |
1995-08-18 |
2023-08-12 |
rat |
| R B Rothman, M L Silverthorn, M H Baumann, C B Goodman, J L Cadet, D Matecka, K C Rice, F I Carroll, J B Wang, G R Uh. Studies of the biogenic amine transporters. VI. Characterization of a novel cocaine binding site, identified with [125I]RTI-55, in membranes prepared from whole rat brain minus caudate. The Journal of pharmacology and experimental therapeutics. vol 274. issue 1. 1995-08-18. PMID:7616423. |
previous studies showed that the cocaine analog [125i]rti-55 labels dopamine and serotonergic (5-ht) biogenic amine transporters (bats) with high affinity. |
1995-08-18 |
2023-08-12 |
rat |
| S R Jones, P A Garris, R M Wightma. Different effects of cocaine and nomifensine on dopamine uptake in the caudate-putamen and nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 274. issue 1. 1995-08-18. PMID:7616424. |
different effects of cocaine and nomifensine on dopamine uptake in the caudate-putamen and nucleus accumbens. |
1995-08-18 |
2023-08-12 |
rat |