| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S H Lee, M Y Chang, K H Lee, B S Park, Y S Lee, H R Chin, Y S Le. Importance of valine at position 152 for the substrate transport and 2beta-carbomethoxy-3beta-(4-fluorophenyl)tropane binding of dopamine transporter. Molecular pharmacology. vol 57. issue 5. 2000-05-25. PMID:10779370. |
human and bovine dopamine transporters (dat) demonstrate discrete functional differences in dopamine (da), 1-methyl-4-phenylpyridium (mpp(+)) transport, and cocaine analog binding. |
2000-05-25 |
2023-08-12 |
human |
| C W Bradberry, R L Barrett-Larimore, P Jatlow, S R Rubin. Impact of self-administered cocaine and cocaine cues on extracellular dopamine in mesolimbic and sensorimotor striatum in rhesus monkeys. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 10. 2000-05-25. PMID:10804227. |
impact of self-administered cocaine and cocaine cues on extracellular dopamine in mesolimbic and sensorimotor striatum in rhesus monkeys. |
2000-05-25 |
2023-08-12 |
human |
| C W Bradberry, R L Barrett-Larimore, P Jatlow, S R Rubin. Impact of self-administered cocaine and cocaine cues on extracellular dopamine in mesolimbic and sensorimotor striatum in rhesus monkeys. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 10. 2000-05-25. PMID:10804227. |
studies were conducted to determine the impact of self-administered cocaine on extracellular striatal dopamine in four rhesus monkeys. |
2000-05-25 |
2023-08-12 |
human |
| C W Bradberry, R L Barrett-Larimore, P Jatlow, S R Rubin. Impact of self-administered cocaine and cocaine cues on extracellular dopamine in mesolimbic and sensorimotor striatum in rhesus monkeys. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 10. 2000-05-25. PMID:10804227. |
large (fivefold to eightfold) increases in extracellular dopamine after a self-administered infusion of 0.5 mg/kg cocaine were quite rapid and matched the time course of reported subjective effects in human laboratory studies. |
2000-05-25 |
2023-08-12 |
human |
| M Barrot, M Marinelli, D N Abrous, F Rougé-Pont, M Le Moal, P V Piazz. The dopaminergic hyper-responsiveness of the shell of the nucleus accumbens is hormone-dependent. The European journal of neuroscience. vol 12. issue 3. 2000-05-22. PMID:10762327. |
the decrease in dopamine observed in the shell had a postsynaptic impact, as shown by less induction of fos-like proteins selectively in the shell in response to cocaine. |
2000-05-22 |
2023-08-12 |
rat |
| M Barrot, M Marinelli, D N Abrous, F Rougé-Pont, M Le Moal, P V Piazz. The dopaminergic hyper-responsiveness of the shell of the nucleus accumbens is hormone-dependent. The European journal of neuroscience. vol 12. issue 3. 2000-05-22. PMID:10762327. |
remained unchanged after adrenalectomy, suggesting that the changes in fos expression after cocaine injection were likely to depend on changes in extracellular dopamine levels rather than on changes in postsynaptic sensitivity to dopamine. |
2000-05-22 |
2023-08-12 |
rat |
| F Weiss, C S Maldonado-Vlaar, L H Parsons, T M Kerr, D L Smith, O Ben-Shaha. Control of cocaine-seeking behavior by drug-associated stimuli in rats: effects on recovery of extinguished operant-responding and extracellular dopamine levels in amygdala and nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 97. issue 8. 2000-05-17. PMID:10760299. |
exposure to the cocaine sdelta significantly increased dopamine efflux in the nacc and amygdala as measured by intracranial microdialysis in a separate group of rats. |
2000-05-17 |
2023-08-12 |
rat |
| D W Johnson, P Eodice, H Winterbottom, D J Mokle. Decreased accumbens dopamine release after cocaine challenge in behaviorally sensitized female rats. Pharmacology, biochemistry, and behavior. vol 65. issue 4. 2000-05-10. PMID:10764919. |
decreased accumbens dopamine release after cocaine challenge in behaviorally sensitized female rats. |
2000-05-10 |
2023-08-12 |
rat |
| D W Johnson, P Eodice, H Winterbottom, D J Mokle. Decreased accumbens dopamine release after cocaine challenge in behaviorally sensitized female rats. Pharmacology, biochemistry, and behavior. vol 65. issue 4. 2000-05-10. PMID:10764919. |
the effects of the competitive nmda receptor antagonist cpp on the initiation of behavioral sensitization to acute cocaine and basal and acute cocaine-induced dopamine (da) release in the nucleus accumbens (nac) were assessed in female sprague-dawley rats. |
2000-05-10 |
2023-08-12 |
rat |
| K G Anderson, F van Haare. Effects of SCH-23390 and raclopride on cocaine discrimination in male and female Wistar rats. Pharmacology, biochemistry, and behavior. vol 65. issue 4. 2000-05-10. PMID:10764921. |
following the determination of the cocaine generalization gradient, the dopamine d(1) antagonist sch-23390 (0.01-0.10 mg/kg) and the dopamine d(2) antagonist raclopride (0.1-1.6 mg/kg) were administered (independently) prior to the injection of the training dose of cocaine (10.0 mg/kg). |
2000-05-10 |
2023-08-12 |
rat |
| Z Lin, M Itokawa, G R Uh. Dopamine transporter proline mutations influence dopamine uptake, cocaine analog recognition, and expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 14. issue 5. 2000-05-01. PMID:10744628. |
dopamine transporter proline mutations influence dopamine uptake, cocaine analog recognition, and expression. |
2000-05-01 |
2023-08-12 |
Not clear |
| Z Lin, M Itokawa, G R Uh. Dopamine transporter proline mutations influence dopamine uptake, cocaine analog recognition, and expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 14. issue 5. 2000-05-01. PMID:10744628. |
the dopamine transporter (dat) mediates complex actions in recognizing cocaine and in recognizing and translocating dopamine, sodium, and chloride. |
2000-05-01 |
2023-08-12 |
Not clear |
| Z Lin, M Itokawa, G R Uh. Dopamine transporter proline mutations influence dopamine uptake, cocaine analog recognition, and expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 14. issue 5. 2000-05-01. PMID:10744628. |
we examine effects of these modifications on dat expression, dopamine uptake, and cocaine analog binding. |
2000-05-01 |
2023-08-12 |
Not clear |
| Z Lin, M Itokawa, G R Uh. Dopamine transporter proline mutations influence dopamine uptake, cocaine analog recognition, and expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 14. issue 5. 2000-05-01. PMID:10744628. |
five mutations decrease dopamine affinities more than threefold without significantly decreasing cocaine analog affinities. |
2000-05-01 |
2023-08-12 |
Not clear |
| Z Lin, M Itokawa, G R Uh. Dopamine transporter proline mutations influence dopamine uptake, cocaine analog recognition, and expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 14. issue 5. 2000-05-01. PMID:10744628. |
one decreases cocaine analog affinity without decreasing dopamine affinity. |
2000-05-01 |
2023-08-12 |
Not clear |
| Z Lin, M Itokawa, G R Uh. Dopamine transporter proline mutations influence dopamine uptake, cocaine analog recognition, and expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 14. issue 5. 2000-05-01. PMID:10744628. |
two mutations decrease affinities for both dopamine and cocaine analog. |
2000-05-01 |
2023-08-12 |
Not clear |
| Z Lin, M Itokawa, G R Uh. Dopamine transporter proline mutations influence dopamine uptake, cocaine analog recognition, and expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 14. issue 5. 2000-05-01. PMID:10744628. |
these dat proline mutants identify dat regions likely for dopamine translocation and for recognition of dopamine and cocaine. |
2000-05-01 |
2023-08-12 |
Not clear |
| P W Czoty, J B Justice, L L Howel. Cocaine-induced changes in extracellular dopamine determined by microdialysis in awake squirrel monkeys. Psychopharmacology. vol 148. issue 3. 2000-04-27. PMID:10755743. |
the behavioral effects of cocaine have been linked to brain dopamine systems. |
2000-04-27 |
2023-08-12 |
monkey |
| R J Bainton, L T Tsai, C M Singh, M S Moore, W S Neckameyer, U Heberlei. Dopamine modulates acute responses to cocaine, nicotine and ethanol in Drosophila. Current biology : CB. vol 10. issue 4. 2000-04-25. PMID:10704411. |
dopamine modulates acute responses to cocaine, nicotine and ethanol in drosophila. |
2000-04-25 |
2023-08-12 |
drosophila_melanogaster |
| H Li, S Chaney, I J Roberts, M Forte, J Hirs. Ectopic G-protein expression in dopamine and serotonin neurons blocks cocaine sensitization in Drosophila melanogaster. Current biology : CB. vol 10. issue 4. 2000-04-25. PMID:10704417. |
ectopic g-protein expression in dopamine and serotonin neurons blocks cocaine sensitization in drosophila melanogaster. |
2000-04-25 |
2023-08-12 |
drosophila_melanogaster |