| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D E Fordyce, R P Farra. Effect of physical activity on hippocampal high affinity choline uptake and muscarinic binding: a comparison between young and old F344 rats. Brain research. vol 541. issue 1. 1991-06-19. PMID:2029624. |
in the present study, specific markers of hippocampal cholinergic function, high-affinity choline uptake (hacu) and muscarinic quinuclidinylbenzilate (qnb) binding, were shown to be altered by endurance training (6 months of treadmill running, 5 days/week, 30 min/day). |
1991-06-19 |
2023-08-11 |
rat |
| D F Emerich, T J Wals. Ganglioside AGF2 prevents the cognitive impairments and cholinergic cell loss following intraventricular colchicine. Experimental neurology. vol 112. issue 3. 1991-06-17. PMID:2029933. |
colchicine also produced significant decreases in hippocampal chat activity and high affinity choline uptake that were prevented by prior treatment with agf2. |
1991-06-17 |
2023-08-11 |
rat |
| J C Cassel, R Jackisch, M Duschek, J M Hornsperger, M H Richards, C Kelche, G Hertting, B Wil. Long term effects of septohippocampal lesions and intrahippocampal grafts on acetylcholine concentration, muscarinic stimulated formation of inositol phospholipids and electrically evoked release of neurotransmitters in the rat hippocampus. Experimental brain research. vol 83. issue 3. 1991-06-07. PMID:2026203. |
the long term (8-10 months post-surgery) effects of these treatments were examined in the hippocampus for the following variables: concentration of hippocampal acetylcholine (ach), muscarinic-stimulated (carbachol) formation of inositol monophosphate, accumulation of tritiated choline, noradrenaline (3h-na) and serotonin (3h-5-ht), electrically evoked release of 3h-acetylcholine (3h-ach), 3h-na and 3h-5-ht, and choline acetyltransferase (chat) activity. |
1991-06-07 |
2023-08-11 |
rat |
| M R Auroux, E M Dulioust, N Y Nawar, S G Yacoub, E H Kempf, A B Ebe. Cyclophosphamide in the male rat: cerebral biochemical changes in progeny. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 44. issue 10. 1991-05-20. PMID:2085667. |
biochemical analyses of the brains of the offspring of treated males in the first and second generations showed a diminished activity of hippocampal choline acetyl-transferase. |
1991-05-20 |
2023-08-11 |
rat |
| J C Cassel, C Kelche, J M Hornsperger, R Jackisch, G Hertting, B E Wil. Graft-induced learning impairment despite graft-enhanced cholinergic functions in the hippocampus of rats with septohippocampal lesions. Brain research. vol 534. issue 1-2. 1991-04-18. PMID:2073591. |
effects of aspirative fimbria-fornix lesions and intrahippocampal grafts of fetal septal-diagonal band or hippocampal tissue were examined, in long evans female rats, on spontaneous alternation, radial maze learning, hippocampal acetylcholine concentrations and [3h]choline accumulation by hippocampal slices. |
1991-04-18 |
2023-08-11 |
rat |
| J C Cassel, C Kelche, J M Hornsperger, R Jackisch, G Hertting, B E Wil. Graft-induced learning impairment despite graft-enhanced cholinergic functions in the hippocampus of rats with septohippocampal lesions. Brain research. vol 534. issue 1-2. 1991-04-18. PMID:2073591. |
septal-diagonal band grafts increased hippocampal acetylcholine levels as well as [3h]choline accumulation of tissue (when incubated for 45 min), but they had no effect on alternation rates and further impaired radial maze performances. |
1991-04-18 |
2023-08-11 |
rat |
| B Djuricic, S R Olson, H M Assaf, T S Whittingham, W D Lust, L R Drewe. Formation of free choline in brain tissue during in vitro energy deprivation. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 11. issue 2. 1991-04-01. PMID:1997502. |
free choline and atp contents were measured in mongolian gerbil hippocampal slices (tissue) and incubation media (media) during exposure to 30 min of aglycemia, high potassium, anoxia, or ischemia. |
1991-04-01 |
2023-08-11 |
Not clear |
| G M Gilad, V H Gilad, Y Tizab. Aging and stress-induced changes in choline and glutamate uptake in hippocampus and septum of two rat strains differing in longevity and reactivity to stressors. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 8. issue 6. 1991-03-25. PMID:1981122. |
aging and stress-induced changes in choline and glutamate uptake in hippocampus and septum of two rat strains differing in longevity and reactivity to stressors. |
1991-03-25 |
2023-08-11 |
rat |
| G M Gilad, V H Gilad, Y Tizab. Aging and stress-induced changes in choline and glutamate uptake in hippocampus and septum of two rat strains differing in longevity and reactivity to stressors. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 8. issue 6. 1991-03-25. PMID:1981122. |
the noted exception was that choline uptake levels, which were reduced in the hippocampus of unhandled aged wky rats, remained unchanged after stress. |
1991-03-25 |
2023-08-11 |
rat |
| K A Sherman, E Friedma. Pre- and post-synaptic cholinergic dysfunction in aged rodent brain regions: new findings and an interpretative review. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 8. issue 6. 1991-03-25. PMID:2288244. |
this study therefore compared choline acetyltransferase activity (as a structural marker) and sodium-dependent high affinity choline uptake (which reflects both ongoing cholinergic neuronal activity and structural integrity) in the hippocampus, cortex and straitum of male c57bl mice at 3-4, 10-12 or 28-32 months of age. |
1991-03-25 |
2023-08-11 |
mouse |
| A Horita, M A Carin. Centrally administered vasopressin antagonizes pentobarbital-induced narcosis and depression of hippocampal cholinergic activity. Peptides. vol 11. issue 5. 1991-03-18. PMID:1980941. |
avp also increased hippocampal sodium-dependent high affinity choline uptake activity that had been depressed by the barbiturate. |
1991-03-18 |
2023-08-11 |
rat |
| H Lai, M A Carino, A Horita, A W Gu. Corticotropin-releasing factor antagonist blocks microwave-induced decreases in high-affinity choline uptake in the rat brain. Brain research bulletin. vol 25. issue 4. 1991-02-26. PMID:2271963. |
acute (45-min) irradiation with pulsed low-level microwaves (2450-mhz, 2 microseconds pulses at 500 pps, average power density of 1 mw/cm2, whole-body average specific absorption rate of 0.6 w/kg) decreased sodium-dependent high-affinity choline uptake (hacu) activity in the frontal cortex and hippocampus of the rat. |
1991-02-26 |
2023-08-11 |
rat |
| C Harel-Dupas, I Cloëz, G Fillio. The inhibitory effect of trifluoromethylphenylpiperazine on [3H]acetylcholine release in guinea pig hippocampal synaptosomes is mediated by a 5-hydroxytryptamine1 receptor distinct from 1A, 1B, and 1C subtypes. Journal of neurochemistry. vol 56. issue 1. 1991-02-15. PMID:1824781. |
the effect of the serotonergic receptor agonist 1-(m-trifluoromethylphenyl)piperazine (tfmpp) was studied on the k(+)-evoked [3h]acetylcholine [( 3h]ach) release from guinea pig hippocampal synaptosomes loaded with [3h]choline. |
1991-02-15 |
2023-08-11 |
Not clear |
| H Lai, M A Carin. Effects of noise on high-affinity choline uptake in the frontal cortex and hippocampus of the rat are blocked by intracerebroventricular injection of corticotropin-releasing factor antagonist. Brain research. vol 527. issue 2. 1991-01-24. PMID:2253041. |
effects of noise on high-affinity choline uptake in the frontal cortex and hippocampus of the rat are blocked by intracerebroventricular injection of corticotropin-releasing factor antagonist. |
1991-01-24 |
2023-08-11 |
rat |
| H Lai, M A Carin. Effects of noise on high-affinity choline uptake in the frontal cortex and hippocampus of the rat are blocked by intracerebroventricular injection of corticotropin-releasing factor antagonist. Brain research. vol 527. issue 2. 1991-01-24. PMID:2253041. |
acute exposure (20 min) to loud noise (100 db) decreased sodium-dependent high-affinity choline uptake activities in the frontal cortex and hippocampus of the rat. |
1991-01-24 |
2023-08-11 |
rat |
| H Lai, M A Carin. Effects of noise on high-affinity choline uptake in the frontal cortex and hippocampus of the rat are blocked by intracerebroventricular injection of corticotropin-releasing factor antagonist. Brain research. vol 527. issue 2. 1991-01-24. PMID:2253041. |
intracerebroventricular injection of crf (1 microgram) also decreased high-affinity choline uptake in the frontal cortex and the hippocampus of the rat, and these effects of crf could be blocked by pretreating the animal with the narcotic antagonist naltrexone (1 mg/kg, i.p.). |
1991-01-24 |
2023-08-11 |
rat |
| C Lebrun, T P Durkin, A Marighetto, R Jaffar. A comparison of the working memory performances of young and aged mice combined with parallel measures of testing and drug-induced activations of septo-hippocampal and nbm-cortical cholinergic neurones. Neurobiology of aging. vol 11. issue 5. 1990-12-12. PMID:2234282. |
the drug injection resulted in a very large (+70%) increase in hippocampal high-affinity choline uptake and with amplitudes which did not vary significantly between young and aged subjects. |
1990-12-12 |
2023-08-11 |
mouse |
| J D Brioni, M W Decker, L P Gamboa, I Izquierdo, J L McGaug. Muscimol injections in the medial septum impair spatial learning. Brain research. vol 522. issue 2. 1990-12-07. PMID:2224525. |
rate of learning of the fixed location was significantly impaired in rats given pretraining muscimol injections in the medial septum at doses (1.0 and 5.0 nmol) that significantly reduced hippocampal high-affinity choline uptake (hacu). |
1990-12-07 |
2023-08-11 |
rat |
| T Suzuki, Y Kashima, K Kawashim. Hemicholinium-3-resistant choline uptake system linked to acetylcholine synthesis in the rat hippocampus. Neuroscience letters. vol 105. issue 1-2. 1990-12-06. PMID:2485880. |
hemicholinium-3-resistant choline uptake system linked to acetylcholine synthesis in the rat hippocampus. |
1990-12-06 |
2023-08-11 |
rat |
| T Suzuki, Y Kashima, K Kawashim. Hemicholinium-3-resistant choline uptake system linked to acetylcholine synthesis in the rat hippocampus. Neuroscience letters. vol 105. issue 1-2. 1990-12-06. PMID:2485880. |
these results indicate that both the hacu and hc-3-resistant choline uptake systems are linked to ach synthesis in the hippocampus. |
1990-12-06 |
2023-08-11 |
rat |