| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Hadjiconstantinou, N S Karadsheh, A K Rattan, G A Tejwani, J G Fitkin, N H Nef. GM1 ganglioside enhances cholinergic parameters in the brain of senescent rats. Neuroscience. vol 46. issue 3. 1992-04-13. PMID:1545916. |
we have administered gm1, to young (three months old) or senescent (22-24 months old) rats and evaluated acetylcholine and choline content, choline acetyltransferase and acetylcholinesterase activity as well as choline uptake in striatum, hippocampus and frontal cortex. |
1992-04-13 |
2023-08-11 |
rat |
| D E Fordyce, R P Farra. Enhancement of spatial learning in F344 rats by physical activity and related learning-associated alterations in hippocampal and cortical cholinergic functioning. Behavioural brain research. vol 46. issue 2. 1992-03-23. PMID:1664728. |
cholinergic analysis included resting and depolarization-induced activation of high-affinity choline uptake and muscarinic receptor binding in the hippocampus, parietal cortex and frontal cortex. |
1992-03-23 |
2023-08-11 |
rat |
| D E Fordyce, R P Farra. Enhancement of spatial learning in F344 rats by physical activity and related learning-associated alterations in hippocampal and cortical cholinergic functioning. Behavioural brain research. vol 46. issue 2. 1992-03-23. PMID:1664728. |
concomitant with enhanced behavioral performance were neurochemical changes of a reduction in hippocampal high-affinity choline uptake, an upregulation of muscarinic receptor density, and an increase in high-affinity choline uptake 24 h after spatial memory testing (p less than 0.05). |
1992-03-23 |
2023-08-11 |
rat |
| D E Fordyce, R P Farra. Enhancement of spatial learning in F344 rats by physical activity and related learning-associated alterations in hippocampal and cortical cholinergic functioning. Behavioural brain research. vol 46. issue 2. 1992-03-23. PMID:1664728. |
these data indicate that the chronic running-induced alterations in hippocampal high-affinity choline uptake and upregulation of muscarinic receptor density, in combination with enhancement of high-affinity choline uptake related to spatial learning, may contribute to the enhanced spatial learning performance of chronic-run rats. |
1992-03-23 |
2023-08-11 |
rat |
| K A Sherman, G E Gibson, P Perrino, K Garret. Acetylcholine formation from glucose following acute choline supplementation. Neurochemical research. vol 16. issue 9. 1992-03-19. PMID:1784327. |
a two to three fold elevation of brain choline did not alter ach levels or [u-14c]glucose incorporation into ach in the cortex, hippocampus or striatum. |
1992-03-19 |
2023-08-11 |
Not clear |
| K A Sherman, G E Gibson, P Perrino, K Garret. Acetylcholine formation from glucose following acute choline supplementation. Neurochemical research. vol 16. issue 9. 1992-03-19. PMID:1784327. |
although atropine stimulated ach formation from [u-14c]glucose in hippocampus, two to three fold increases in brain choline did not augment ach synthesis or content in atropine pretreated animals. |
1992-03-19 |
2023-08-11 |
Not clear |
| M R Marien, J W Richard, C Allaire, C A Alta. Suppression of in vivo neostriatal acetylcholine release by vesamicol: evidence for a functional role of vesamicol receptors in brain. Journal of neurochemistry. vol 57. issue 6. 1991-12-18. PMID:1658227. |
in time course studies, a single intraperitoneal dose of dl-vesamicol (5 mg/kg) rapidly and reversibly (within 2 h) doubled the content of acetylcholine in the striatum and hippocampus, without affecting choline levels or the rate of transmitter synthesis. |
1991-12-18 |
2023-08-11 |
rat |
| T Arendt, M M Schugens, V Big. The cholinergic system and memory: amelioration of ethanol-induced memory deficiency by physostigmine in rat. Acta neurobiologiae experimentalis. vol 50. issue 4-5. 1991-11-13. PMID:2130647. |
profound reductions of acetylcholine content, the activities of choline acetyltransferase and acetylcholinesterase and choline uptake were observed in the cortex, hippocampus, substantia innominata and striatum four weeks after withdrawal from ethanol. |
1991-11-13 |
2023-08-11 |
rat |
| S Laganière, J Corey, X C Tang, E Wülfert, I Hani. Acute and chronic studies with the anticholinesterase Huperzine A: effect on central nervous system cholinergic parameters. Neuropharmacology. vol 30. issue 7. 1991-11-04. PMID:1922687. |
in the hippocampus high affinity choline transport was attenuated by 25%, whereas no effect in the striatum was observed. |
1991-11-04 |
2023-08-11 |
rat |
| S Laganière, J Corey, X C Tang, E Wülfert, I Hani. Acute and chronic studies with the anticholinesterase Huperzine A: effect on central nervous system cholinergic parameters. Neuropharmacology. vol 30. issue 7. 1991-11-04. PMID:1922687. |
high affinity choline transport in the hippocampus was reduced by 28%, 45 min after the last injection, but in the striatum there was no effect. |
1991-11-04 |
2023-08-11 |
rat |
| S Laganière, J Corey, X C Tang, E Wülfert, I Hani. Acute and chronic studies with the anticholinesterase Huperzine A: effect on central nervous system cholinergic parameters. Neuropharmacology. vol 30. issue 7. 1991-11-04. PMID:1922687. |
thus, acute or chronic treatment with huperzine a: did not alter chat; reduced high affinity choline transport in the hippocampus in a transient manner; and had a longer duration of action as an ache inhibitor than physostigmine. |
1991-11-04 |
2023-08-11 |
rat |
| L Wecke. The synthesis and release of acetylcholine by depolarized hippocampal slices is increased by increased choline available in vitro prior to stimulation. Journal of neurochemistry. vol 57. issue 4. 1991-10-21. PMID:1895099. |
the synthesis and release of acetylcholine by depolarized hippocampal slices is increased by increased choline available in vitro prior to stimulation. |
1991-10-21 |
2023-08-11 |
Not clear |
| L Wecke. The synthesis and release of acetylcholine by depolarized hippocampal slices is increased by increased choline available in vitro prior to stimulation. Journal of neurochemistry. vol 57. issue 4. 1991-10-21. PMID:1895099. |
the objective of these experiments was to determine whether preincubating hippocampal slices with choline provides precursor that can be used during a subsequent incubation to support or enhance the synthesis of acetylcholine (ach). |
1991-10-21 |
2023-08-11 |
Not clear |
| P A Lapchak, D J Jenden, F Heft. Compensatory elevation of acetylcholine synthesis in vivo by cholinergic neurons surviving partial lesions of the septohippocampal pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 11. issue 9. 1991-10-03. PMID:1880551. |
partial lesions decreased high-affinity choline uptake into hippocampal synaptosomes by 52%. |
1991-10-03 |
2023-08-11 |
Not clear |
| P A Lapchak, D J Jenden, F Heft. Compensatory elevation of acetylcholine synthesis in vivo by cholinergic neurons surviving partial lesions of the septohippocampal pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 11. issue 9. 1991-10-03. PMID:1880551. |
levels of endogenous ach and choline measured in the hippocampus following partial lesions were similar to that of control values. |
1991-10-03 |
2023-08-11 |
Not clear |
| D E Fordyce, R P Farra. Physical activity effects on hippocampal and parietal cortical cholinergic function and spatial learning in F344 rats. Behavioural brain research. vol 43. issue 2. 1991-09-13. PMID:1867753. |
single bouts of physical activity elevated hippocampal and cortical high affinity choline uptake, whereas chronic physical activity significantly reduced only hippocampal high affinity choline uptake (hacu) and elevated muscarinic (qnb) receptor density. |
1991-09-13 |
2023-08-11 |
rat |
| G Hasey, I Hani. Plasma corticosterone is increased and correlated with brain acetylcholine in physostigmine- but not in neostigmine-treated rats. Psychoneuroendocrinology. vol 15. issue 5-6. 1991-09-13. PMID:2101961. |
either 15 or 30 min later the number and intensity of observable cholinomimetic effects (oce) was determined, plasma was collected for corticosterone (cst) measurement, and the cerebral cortex, striatum, hippocampus and hypothalamus were removed after microwave treatment for the measurement of tissue acetylcholine (ach) and choline (ch) concentrations. |
1991-09-13 |
2023-08-11 |
rat |
| A Horita, M A Carino, Y Nishimur. D1 agonist SKF 38393 antagonizes pentobarbital-induced narcosis and depression of hippocampal and cortical cholinergic activity in rats. Life sciences. vol 49. issue 8. 1991-09-12. PMID:1865753. |
skf 38393 also increased sodium dependent high affinity choline uptake (hacu) in cortical and hippocampal synaptosomes that had been depressed by pentobarbital. |
1991-09-12 |
2023-08-11 |
rat |
| D E Fordyce, R P Farra. Effect of physical activity on hippocampal high affinity choline uptake and muscarinic binding: a comparison between young and old F344 rats. Brain research. vol 541. issue 1. 1991-06-19. PMID:2029624. |
effect of physical activity on hippocampal high affinity choline uptake and muscarinic binding: a comparison between young and old f344 rats. |
1991-06-19 |
2023-08-11 |
rat |
| D E Fordyce, R P Farra. Effect of physical activity on hippocampal high affinity choline uptake and muscarinic binding: a comparison between young and old F344 rats. Brain research. vol 541. issue 1. 1991-06-19. PMID:2029624. |
in the present study, specific markers of hippocampal cholinergic function, high-affinity choline uptake (hacu) and muscarinic quinuclidinylbenzilate (qnb) binding, were shown to be altered by endurance training (6 months of treadmill running, 5 days/week, 30 min/day). |
1991-06-19 |
2023-08-11 |
rat |