| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S S Ferguson, R J Rylett, B Collie. Regulation of rat brain synaptosomal [3H]hemicholinium-3 binding and [3H]choline transport sites following exposure to choline mustard aziridinium ion. Journal of neurochemistry. vol 63. issue 4. 1994-11-01. PMID:7931285. |
in contrast, the preexposure of hippocampal synaptosomes to the mustard in the presence of a calcium ionophore (a23187) reduced the concentration of inhibitor needed to prevent the activation of [3h]hemicholinium-3 binding and choline uptake. |
1994-11-01 |
2023-08-12 |
rat |
| P A Lapchak, D M Araujo, F Heft. Effects of chronic nerve growth factor treatment on hippocampal [3H]cytisine/nicotinic binding sites and presynaptic nicotinic receptor function following fimbrial transections. Neuroscience. vol 60. issue 2. 1994-09-23. PMID:8072684. |
more specifically, chronic ngf treatment attenuates lesion-induced reductions in hippocampal chat activity and high-affinity choline uptake, the end-result of which is an enhanced capacity to synthesize acetylcholine. |
1994-09-23 |
2023-08-12 |
Not clear |
| M Singh, E M Meyer, W J Millard, J W Simpkin. Ovarian steroid deprivation results in a reversible learning impairment and compromised cholinergic function in female Sprague-Dawley rats. Brain research. vol 644. issue 2. 1994-09-08. PMID:8050041. |
active avoidance behavior and choline acetyltransferase (chat) activity in the frontal cortex and hippocampus were assessed at 5 and 28 weeks postovariectomy while performance on the morris water task and high-affinity choline uptake (hacu) were measured only at the 5-week time point. |
1994-09-08 |
2023-08-12 |
rat |
| B J Tarricone, J R Simon, W C Lo. Intrahippocampal transplants of septal cholinergic neurons: choline acetyltransferase activity, muscarinic receptor binding, and spatial memory function. Brain research. vol 632. issue 1-2. 1994-05-11. PMID:8149244. |
further studies have revealed that hippocampal cholinergic activity, as measured by high affinity choline uptake, correlates significantly with performance on tests of spatial memory function. |
1994-05-11 |
2023-08-12 |
Not clear |
| K Yamasaki, M Kikuoka, H Nishi, Y Kokusenya, T Miyamoto, M Matsuo, T Sat. Contents of lecithin and choline in crude drugs. Chemical & pharmaceutical bulletin. vol 42. issue 1. 1994-04-13. PMID:8124757. |
the results showed that cervi parvum cornu, kokurozin, foenigraeci semen and psoraleae semen contained more lecithin than other crude drugs, while angelicae radix, foenigraeci semen, psoraleae semen, and especially hippocampus were found to contain more choline than other crude drugs. |
1994-04-13 |
2023-08-12 |
Not clear |
| J Klein, T Holler, E Cappel, A Köppen, K Löffelhol. Release of choline from rat brain under hypoxia: contribution from phospholipase A2 but not from phospholipase D. Brain research. vol 630. issue 1-2. 1994-04-05. PMID:8118702. |
in hippocampal slices from rat brain, hypoxia increased the release of choline into the superfusion medium. |
1994-04-05 |
2023-08-12 |
rat |
| J Kiss, E M Shooter, A J Pate. A low-affinity nerve growth factor receptor antibody is internalized and retrogradely transported selectively into cholinergic neurons of the rat basal forebrain. Neuroscience. vol 57. issue 2. 1994-03-29. PMID:8115039. |
moreover, in contrast to specific transport of p75ngfr antibody into cholinergic neurons, when wheat germ agglutinin-colloidal gold was injected into the hippocampus at the same levels, it was taken up and retrogradely transported into both choline acetyltransferase-positive cholinergic and parvalbumin-immunoreactive gabaergic neurons in the medial septum-diagonal band complex. |
1994-03-29 |
2023-08-12 |
rat |
| W Reimann, G D Bartoszyk, U Köllhofer, F Schneider, U Schoenher. Effects of ageing and long-term operant conditioning on behavior and presynaptic cholinergic and dopaminergic neuronal mechanisms in rats. Archives internationales de pharmacodynamie et de therapie. vol 325. 1994-03-22. PMID:8110029. |
hippocampal slices were incubated with [3h]choline, and 3h-uptake and [3h]acetylcholine synthesis were measured. |
1994-03-22 |
2023-08-12 |
rat |
| G Wörtwein, R W Stackman, T J Wals. Vitamin E prevents the place learning deficit and the cholinergic hypofunction induced by AF64A. Experimental neurology. vol 125. issue 1. 1994-03-16. PMID:8307121. |
after completion of behavioral testing, hippocampal high-affinity choline uptake (hachu) was assessed. |
1994-03-16 |
2023-08-12 |
rat |
| A Horita, M A Carino, Y Uka. The analeptic effect of methamphetamine in pentobarbital-narcotized rats is mediated via a dopaminergic-cholinergic mechanism. The Journal of pharmacology and experimental therapeutics. vol 268. issue 1. 1994-03-10. PMID:7905529. |
pentobarbital decreased sodium-dependent high-affinity choline uptake (hacu) in frontal cortex and hippocampus as measured in synaptosomes from treated rats. |
1994-03-10 |
2023-08-12 |
rat |
| T Holler, J Klein, K Löffelhol. Phospholipase C and phospholipase D are independently activated in rat hippocampal slices. Biochemical pharmacology. vol 47. issue 2. 1994-03-10. PMID:8304985. |
in order to investigate a possible g-protein-mediated activation of phospholipase d (pld) and its relationship to the activation of phosphoinositide-specific phospholipase c (pi-plc), we measured the effects of aluminium fluoride and carbachol on choline release, the pld-specific transphosphatidylation reaction (generation of phosphatidylpropanol) and the formation of inositol phosphates in rat hippocampal slices. |
1994-03-10 |
2023-08-12 |
rat |
| R J Rylett, W Davis, S A Walter. Modulation of high-affinity choline carrier activity following incubation of rat hippocampal synaptosomes with hemicholinium-3. Brain research. vol 626. issue 1-2. 1994-02-14. PMID:8281429. |
modulation of high-affinity choline carrier activity following incubation of rat hippocampal synaptosomes with hemicholinium-3. |
1994-02-14 |
2023-08-12 |
rat |
| R J Rylett, W Davis, S A Walter. Modulation of high-affinity choline carrier activity following incubation of rat hippocampal synaptosomes with hemicholinium-3. Brain research. vol 626. issue 1-2. 1994-02-14. PMID:8281429. |
following incubation of rat hippocampal synaptosomes with hemicholinium-3, samples were washed free of the inhibitor and high-affinity choline uptake was measured. |
1994-02-14 |
2023-08-12 |
rat |
| A Marighetto, J Micheau, R Jaffar. Relationships between testing-induced alterations of hippocampal cholinergic activity and memory performance on two spatial tasks in mice. Behavioural brain research. vol 56. issue 2. 1994-01-06. PMID:8240709. |
alterations in hippocampal cholinergic activity associated with different types and/or stages of learning were explored using measures of sodium-dependent high-affinity choline uptake (sdhacu) in the hippocampus of c57bl/6 mice. |
1994-01-06 |
2023-08-12 |
mouse |
| A Ricci, E Bronzetti, J A Vega, F Ament. Oral choline alfoscerate counteracts age-dependent loss of mossy fibres in the rat hippocampus. Mechanisms of ageing and development. vol 66. issue 1. 1993-12-21. PMID:1340517. |
oral choline alfoscerate counteracts age-dependent loss of mossy fibres in the rat hippocampus. |
1993-12-21 |
2023-08-11 |
rat |
| A Ricci, E Bronzetti, J A Vega, F Ament. Oral choline alfoscerate counteracts age-dependent loss of mossy fibres in the rat hippocampus. Mechanisms of ageing and development. vol 66. issue 1. 1993-12-21. PMID:1340517. |
moreover, the number of granule neurons of the hippocampus was higher by about 7% in choline alfoscerate-treated than in control 24-month-old rats. |
1993-12-21 |
2023-08-11 |
rat |
| A Ricci, E Bronzetti, J A Vega, F Ament. Oral choline alfoscerate counteracts age-dependent loss of mossy fibres in the rat hippocampus. Mechanisms of ageing and development. vol 66. issue 1. 1993-12-21. PMID:1340517. |
the above data suggest that choline alfoscerate treatment counteracts some anatomical changes of the rat hippocampus occurring in old age. |
1993-12-21 |
2023-08-11 |
rat |
| Y Ikarashi, A Takahashi, H Ishimaru, T Arai, Y Maruyam. Effects of choline-free plasma induced by choline oxidase on regional levels of choline and acetylcholine in rat brain. Brain research bulletin. vol 32. issue 6. 1993-12-14. PMID:8221157. |
choline-free plasma (cfp) was induced in rats by intravenous (iv) injection of 56.0 x 10(2) units kg-1 of choline oxidase (cho) which completely metabolized the free ch circulating in the plasma for at least 15.0 h and caused subsequent significant decrease in the concentration of free ch in the three brain regions examined, the striatum, hippocampus, and cortex. |
1993-12-14 |
2023-08-12 |
rat |
| J Peeling, L Shoemaker, T Gauthier, A Benarroch, G R Sutherland, G Y Minu. Cerebral metabolic and histological effects of thioacetamide-induced liver failure. The American journal of physiology. vol 265. issue 3 Pt 1. 1993-11-23. PMID:8214078. |
at all stages of he, taurine was decreased in the neocortex and hippocampus, and glutamate and choline compounds were decreased in the frontal cortex. |
1993-11-23 |
2023-08-12 |
rat |
| L J Fisher, M Schinstine, P Salvaterra, A J Dekker, L Thal, F H Gag. In vivo production and release of acetylcholine from primary fibroblasts genetically modified to express choline acetyltransferase. Journal of neurochemistry. vol 61. issue 4. 1993-10-21. PMID:8376990. |
these dchat-expressing cells were then implanted into the intact hippocampus of adult rats and in vivo microdialysis was performed 7-10 days after grafting to assess the ability of the cells to produce ach and respond to exogenous choline in vivo. |
1993-10-21 |
2023-08-12 |
rat |