| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A P Zis, G G Nomikos, E E Brown, G Damsma, H C Fibige. Neurochemical effects of electrically and chemically induced seizures: an in vivo microdialysis study in the rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 7. issue 3. 1992-11-19. PMID:1382432. |
this study examined the effects of electroconvulsive shock (ecs) on interstitial concentrations of serotonin (5-ht), its metabolite 5-hydroxyindoleacetic acid (5-hiaa), acetylcholine and choline, and the dopamine metabolite homovanillic acid (hva) in the hippocampus of freely moving rats using online brain microdialysis. |
1992-11-19 |
2023-08-11 |
rat |
| H Lai, M A Carin. Opioid receptor subtypes mediating the noise-induced decreases in high-affinity choline uptake in the rat brain. Pharmacology, biochemistry, and behavior. vol 42. issue 3. 1992-11-18. PMID:1329116. |
acute (20 min) exposure to 100-db white noise elicits a naltrexone-sensitive decrease in sodium-dependent high-affinity choline uptake in the frontal cortex and hippocampus of the rat. |
1992-11-18 |
2023-08-11 |
rat |
| H Lai, M A Carin. Opioid receptor subtypes mediating the noise-induced decreases in high-affinity choline uptake in the rat brain. Pharmacology, biochemistry, and behavior. vol 42. issue 3. 1992-11-18. PMID:1329116. |
we found that the noise-induced decrease in high-affinity choline uptake in the hippocampus was blocked by pretreatment with either mu-, delta-, or kappa-opioid-receptor antagonists, whereas the effect of noise on frontal cortical high-affinity choline uptake was blocked by a mu- and delta- but not by a kappa-antagonist. |
1992-11-18 |
2023-08-11 |
rat |
| X Zhang, E Wulfert, I Hani. Development of a sensitive and inexpensive micropush-pull technique for the continuous analysis of brain neurotransmitters and metabolites in vivo. Journal of neuroscience methods. vol 42. issue 1-2. 1992-11-10. PMID:1357236. |
in vivo: [3h]choline (3 microci, 35 nmol) was infused (6 min) into the lateral ventricle and collected by micropush-pull at 10-min intervals for 180 min, from the cerebellomedullary cistern and hippocampus. |
1992-11-10 |
2023-08-11 |
rat |
| J C Cassel, C Kelche, B Neufang, B E Will, G Hertting, R Jackisc. Graft-derived cholinergic reinnervation of the hippocampus prevents a lasting increase of hippocampal noradrenaline concentration induced by septohippocampal damage in rats. Neuroscience letters. vol 138. issue 1. 1992-10-26. PMID:1407663. |
between 9.5 and 10.5 months after grafting surgery, we found the lesions to decrease choline acetyltransferase activity (chat), high affinity synaptosomal uptake of [3h]choline (hacu) and serotonin concentration ([5-ht]), as well as to increase the noradrenaline concentration ([na]) in the dorsal hippocampus. |
1992-10-26 |
2023-08-11 |
rat |
| J B Coutcher, G Cawley, L Wecke. Dietary choline supplementation increases the density of nicotine binding sites in rat brain. The Journal of pharmacology and experimental therapeutics. vol 262. issue 3. 1992-10-22. PMID:1326624. |
chronic supplementation with choline, which increased circulating choline levels by 92%, did not alter binding affinity, but increased significantly the maximal number (bmax) of nicotine binding sites in cortical and hippocampal membranes by 20 and 73%, respectively, compared to animals fed the basal choline diet; the bmax in striatal membranes was unaltered. |
1992-10-22 |
2023-08-11 |
rat |
| R Chen, S E Robinso. The effect of cobrotoxin on cholinergic neurons in the mouse. Life sciences. vol 51. issue 13. 1992-10-09. PMID:1522750. |
there were no obvious changes in the concentrations of ach and choline (ch) in the cortex, hippocampus, hypothalamus, midbrain, striatum, or thalamus of the mouse after injection of an analgesic dose of ct (2 micrograms, i.c.v.). |
1992-10-09 |
2023-08-11 |
mouse |
| A el Tamer, J Corey, E Wülfert, I Hani. Reversible cholinergic changes induced by AF64A in rat hippocampus and possible septal compensatory effect. Neuropharmacology. vol 31. issue 4. 1992-10-09. PMID:1522957. |
high affinity choline transport (hacht) in the hippocampus showed a 35 and 25% decrease but only 14 and 7 days, after injection of 0.25 and 0.5 nmol af64a/side, respectively. |
1992-10-09 |
2023-08-11 |
rat |
| J C Cassel, B Neufang, C Kelche, F Aiple, B E Will, G Hertting, R Jackisc. Effects of septal and/or raphe cell suspension grafts on hippocampal choline acetyltransferase activity, high affinity synaptosomal uptake of choline and serotonin, and behavior in rats with extensive septohippocampal lesions. Brain research. vol 585. issue 1-2. 1992-09-29. PMID:1511308. |
effects of septal and/or raphe cell suspension grafts on hippocampal choline acetyltransferase activity, high affinity synaptosomal uptake of choline and serotonin, and behavior in rats with extensive septohippocampal lesions. |
1992-09-29 |
2023-08-11 |
rat |
| J C Cassel, B Neufang, C Kelche, F Aiple, B E Will, G Hertting, R Jackisc. Effects of septal and/or raphe cell suspension grafts on hippocampal choline acetyltransferase activity, high affinity synaptosomal uptake of choline and serotonin, and behavior in rats with extensive septohippocampal lesions. Brain research. vol 585. issue 1-2. 1992-09-29. PMID:1511308. |
the lesions increased locomotor activity, impaired radial maze learning and, in the dorsal hippocampus, reduced ache positive staining, decreased chat activity (-73%) as well as high affinity uptake of both choline (-81%) and serotonin (-82%). |
1992-09-29 |
2023-08-11 |
rat |
| J C Cassel, B Neufang, C Kelche, F Aiple, B E Will, G Hertting, R Jackisc. Effects of septal and/or raphe cell suspension grafts on hippocampal choline acetyltransferase activity, high affinity synaptosomal uptake of choline and serotonin, and behavior in rats with extensive septohippocampal lesions. Brain research. vol 585. issue 1-2. 1992-09-29. PMID:1511308. |
however, septal transplants increased hippocampal ache positivity, restored chat activity and enhanced choline uptake to 116% and 70% of the values found in sham-operated rats, respectively; they had no significant effect on uptake of serotonin. |
1992-09-29 |
2023-08-11 |
rat |
| J C Cassel, B Neufang, C Kelche, F Aiple, B E Will, G Hertting, R Jackisc. Effects of septal and/or raphe cell suspension grafts on hippocampal choline acetyltransferase activity, high affinity synaptosomal uptake of choline and serotonin, and behavior in rats with extensive septohippocampal lesions. Brain research. vol 585. issue 1-2. 1992-09-29. PMID:1511308. |
transplants from the raphe region had weak effects on hippocampal ache positivity, increased both the chat activity and the choline uptake to 70% ad 38% of the sham-operated rats, respectively, and produced an (over)compensation of the serotonin uptake which reached 324% of the values found in sham-operated rats. |
1992-09-29 |
2023-08-11 |
rat |
| J Gomeza, C Aragón, C Giméne. High-affinity transport of choline and amino acid neurotransmitters in synaptosomes from brain regions after lesioning the nucleus basalis magnocellularis of young and aged rats. Neurochemical research. vol 17. issue 4. 1992-09-28. PMID:1355270. |
uptake of choline, gaba, glutamate and glycine has also been studied in other areas of the brain, namely, hippocampus, olfactory bulb and cerebellum. |
1992-09-28 |
2023-08-11 |
rat |
| D Beracochea, J Micheau, R Jaffar. Memory deficits following chronic alcohol consumption in mice: relationships with hippocampal and cortical cholinergic activities. Pharmacology, biochemistry, and behavior. vol 42. issue 4. 1992-09-25. PMID:1513857. |
parallel neurochemical analysis showed that chronic alcohol intake produced a significant decrease in hippocampal and cortical sodium-dependent high-affinity choline uptake. |
1992-09-25 |
2023-08-11 |
mouse |
| R Bertorelli, D Amoroso, P Girotti, S Consol. Effect of tianeptine on the central cholinergic system: involvement of serotonin. Naunyn-Schmiedeberg's archives of pharmacology. vol 345. issue 3. 1992-08-05. PMID:1620232. |
the drug did not alter choline-o-acetyltransferase and acetylcholinesterase activities suggesting that it did not influence the cholinergic system through direct action on the ach metabolism; furthermore, it did not influence the sodium-dependent high-affinity uptake of choline in striatum, cortex and hippocampus. |
1992-08-05 |
2023-08-11 |
rat |
| I H Ulus, R L Buyukuysal, R J Wurtma. N-methyl-D-aspartate increases acetylcholine release from rat striatum and cortex: its effect is augmented by choline. The Journal of pharmacology and experimental therapeutics. vol 261. issue 3. 1992-07-14. PMID:1602377. |
choline efflux from striatal and cortical (but not hippocampal) slices decreased by 34 to 50% in mg(++)-free medium. |
1992-07-14 |
2023-08-11 |
rat |
| D F Emerich, B A Black, J P Kesslak, C W Cotman, T J Wals. Transplantation of fetal cholinergic neurons into the hippocampus attenuates the cognitive and neurochemical deficits induced by AF64A. Brain research bulletin. vol 28. issue 2. 1992-07-07. PMID:1596741. |
bilateral injections of af64a (3 nmol) into the lateral ventricles produced significant learning and memory impairments together with decreases in hippocampal high-affinity choline uptake (hachu). |
1992-07-07 |
2023-08-11 |
rat |
| J R Krebs, J T Erichsen, V P Bingma. The distribution of neurotransmitters and neurotransmitter-related enzymes in the dorsomedial telencephalon of the pigeon (Columba livia). The Journal of comparative neurology. vol 314. issue 3. 1992-06-23. PMID:1687688. |
putative afferent fibers containing choline acetyltransferase-like, serotonin-like, and tyrosine hydroxylase-like immunoreactivity were seen in a fiber tract passing through the septo-hippocampal junction and along the medial wall of the hippocampal region. |
1992-06-23 |
2023-08-11 |
pigeon |
| G Fisone, T Bartfai, S Nilsson, T Hökfel. Galanin inhibits the potassium-evoked release of acetylcholine and the muscarinic receptor-mediated stimulation of phosphoinositide turnover in slices of monkey hippocampus. Brain research. vol 568. issue 1-2. 1992-06-23. PMID:1726068. |
in the ventral hippocampus of cynomologus monkey, galanin, a 29 amino acid long neuropeptide, reduced the potassium-evoked release of [3h]acetylcholine from slices preloaded with [3h]choline and diminished the carbachol-stimulated accumulation of [3h]inositol polyphosphates in hippocampal microprisms preincubated with myo-[2-3h]inositol. |
1992-06-23 |
2023-08-11 |
monkey |
| G Reine, D Samuel, A Nieoullon, L Kerkerian-Le Gof. Effects of lesion of the cholinergic basal forebrain nuclei on the activity of glutamatergic and GABAergic systems in the rat frontal cortex and hippocampus. Journal of neural transmission. General section. vol 87. issue 3. 1992-06-17. PMID:1581017. |
in a second series of experiments involving bilateral intraventricular injections of af64a, marked survival time-dependent decreases in cat and high affinity choline uptake activities but no significant change in the high affinity glutamate uptake rate were observed in the hippocampus. |
1992-06-17 |
2023-08-11 |
rat |