| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Lindamood, B K Colasant. Effects of delta 9-tetrahydrocannabinol and cannabidiol on sodium-dependent high affinity choline uptake in the rat hippocampus. The Journal of pharmacology and experimental therapeutics. vol 213. issue 2. 1980-06-27. PMID:6245205. |
after direct addition to the hippocampal homogenates (in vitro) both delta 9-thc and cbd inhibited choline uptake, with ic50 values of 4.6 and 15.9 microm, respectively. |
1980-06-27 |
2023-08-12 |
rat |
| W A Hunt, E Majchrowic. Regional differences in high-affinity choline uptake in brain after acute and chronic treatment with ethanol. Drug and alcohol dependence. vol 4. issue 3-4. 1980-04-17. PMID:527480. |
a single dose of ethanol has been shown to affect both striatal and hippocampal high-affinity choline uptake. |
1980-04-17 |
2023-08-11 |
Not clear |
| P D Hrdina, K Elso. High-affinity choline uptake in regions of rat brain and the effect of antidepressants. Canadian journal of physiology and pharmacology. vol 57. issue 6. 1979-12-27. PMID:487267. |
the effect of tricyclic antidepressants, chlorpromazine, and some monoamine oxidase inhibitors on the accumulation of [14c]choline by crude synaptosomal (p2) fraction from different regions of rat brain (cortex, striatum, and hippocampus) was investigated. |
1979-12-27 |
2023-08-11 |
rat |
| M Quik, P C Emson, J Fahrenkrug, L L Iverse. Effect of kainic acid injections and other brain lesions on vasoactive intestinal peptide (VIP)-stimulated formation of cAMP in rat brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 306. issue 3. 1979-10-24. PMID:38409. |
kainic acid injection into several other brain regions, including hippocampus, cortex and hypothalamus also failed to affect the vip-elicited increase in camp in slices, despite reductions in choline acetyl-transferase, glutamate decarboxylase, cyclic nucleotide phosphodiesterase and basal levels of camp. |
1979-10-24 |
2023-08-11 |
rat |
| K A Sherman, M J Zigmond, I Hani. High affinity choline uptake in striatum and hippocampus: differential effects of treatments which release acetylcholine. Life sciences. vol 23. issue 17-18. 1979-02-23. PMID:723454. |
high affinity choline uptake in striatum and hippocampus: differential effects of treatments which release acetylcholine. |
1979-02-23 |
2023-08-11 |
Not clear |
| R Schwarcz, R Zaczek, J T Coyl. Microinjection of kainic acid into the rat hippocampus. European journal of pharmacology. vol 50. issue 3. 1978-11-22. PMID:689077. |
although the specific activity of choline acetyltransferase is unaffected and the specific activity of tyrosine hydroxylase is significantly increased in the injected hippocampus, the synaptosomal high affinity uptake process for [3h]choline and [3h]norepinephrine are significantly reduced at 10 days after injection. |
1978-11-22 |
2023-08-11 |
rat |
| T M Shih, I Hani. Effects of chronic lead exposure on levels of acetylcholine and choline and on acetylcholine turnover rate in rat brain areas in vivo. Psychopharmacology. vol 58. issue 3. 1978-10-18. PMID:98796. |
similarly, no changes in choline (ch) concentrations were found in cortex, hippocampus, or striatum. |
1978-10-18 |
2023-08-11 |
rat |
| T Durkin, G Ayad, A Ebel, P Mande. Regional acetylcholine turnover rates in the brains of three inbred strains of mice: correlation with some interstrain behavioural differences. Brain research. vol 136. issue 3. 1978-01-27. PMID:922496. |
in vivo ach turnover rates have been measured in three regions (hippocampus, caudate nucleus and frontal-parietal cortex) of the brains of each strain by following the rate of formation of labelled ach, in these regions, after a pulse intravenous injection of a tracer dose of 3h labelled choline. |
1978-01-27 |
2023-08-11 |
mouse |
| B Oderfeld-Nowak, A Potempsk. Relationship between changes in the content of acetylcholine and the activities of acetylcholinesterase and choline acetyltransferase in the hippocampus of the rat after septal lesions. Acta neurobiologiae experimentalis. vol 37. issue 3. 1977-10-14. PMID:899888. |
the involvement of other hippocampal neurotransmitters acting through the high-affinity uptake of choline is supposed to play an important role in ach content regulation. |
1977-10-14 |
2023-08-11 |
rat |
| G M Samaras, J F Contrer. Choline: high affinity uptake in vivo by rat hippocampus. Journal of neurochemistry. vol 28. issue 6. 1977-08-25. PMID:874500. |
choline: high affinity uptake in vivo by rat hippocampus. |
1977-08-25 |
2023-08-11 |
rat |
| M J Hirsch, J H Growdon, R J Wurtma. Increase in hippocampal acetylcholine after choline administration. Brain research. vol 125. issue 2. 1977-06-22. PMID:851886. |
increase in hippocampal acetylcholine after choline administration. |
1977-06-22 |
2023-08-11 |
Not clear |
| P Hadházy, J C Szer. The effect of cholinergic drugs on [3H]acetylcholine release from slices of rat hippocampus, striatum and cortex. Brain research. vol 123. issue 2. 1977-05-25. PMID:843927. |
slices from rat hippocampus, striatum or cortex were incubated with l mum [3h] choline and following 75 min superfusion with krebs solution the efflux of radioactivity was measured. |
1977-05-25 |
2023-08-11 |
rat |
| V H Sethy, R H Roth, J R Walters, J Marini, M H Van Woer. Effect of anesthetic doses of gamma-hydroxybutyrate on the acetylcholine content of rat brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 295. issue 1. 1977-02-16. PMID:1004645. |
gamma-hydroxybutyrate did not cause a significant change in the striatal or hippocampal levels of choline. |
1977-02-16 |
2023-08-11 |
rat |
| M J Kuhar, R N DeHaven, H I Yamamura, H Rommel-Spacher, J R Simo. Further evidence for cholinergic habenulo-interpeduncular neurons: pharmacologic and functional characteristics. Brain research. vol 97. issue 2. 1976-01-02. PMID:1175046. |
while the ipn probably has a much denser cholinergic innervation than the hippocampus (as evidenced by much higher ach levels, chac activity and choline uptake levels), it has only one-fourth as many [3h]qnb binding sites (a measure of cholinergic muscarinic receptors). |
1976-01-02 |
2023-08-11 |
Not clear |
| A H Mulder, H I Yamamura, M J Kuhar, S H Snyde. Release of acetylcholine from hippocampal slices by potassium depolarization: dependence on high affinity choline uptake. Brain research. vol 70. issue 2. 1974-06-28. PMID:4825681. |
release of acetylcholine from hippocampal slices by potassium depolarization: dependence on high affinity choline uptake. |
1974-06-28 |
2023-08-11 |
Not clear |
| J A Izquierdo, C M Baratti, M Torrelio, L Arévalo, J L McGaug. Effects of food deprivation, discrimination experience and physostigmine on choline acetylase and acetylcholine esterase in the dorsal hippocampus and frontal cortex of rats. Psychopharmacologia. vol 33. issue 1. 1974-03-05. PMID:4769024. |
effects of food deprivation, discrimination experience and physostigmine on choline acetylase and acetylcholine esterase in the dorsal hippocampus and frontal cortex of rats. |
1974-03-05 |
2023-08-11 |
rat |
| V H Sethy, R H Roth, M J Kuhar, M H Van Woer. Choline and acetylcholine: regional distribution and effect of degeneration of cholinergic nerve terminals in the rat hippocampus. Neuropharmacology. vol 12. issue 9. 1973-12-17. PMID:4746445. |
choline and acetylcholine: regional distribution and effect of degeneration of cholinergic nerve terminals in the rat hippocampus. |
1973-12-17 |
2023-08-11 |
rat |
| V H Sethy, M J Kuhar, R H Roth, M H Van Woert, G K Aghajania. Cholinergic neurons: effect of acute septal lesion on acetylcholine and choline content of rat hippocampus. Brain research. vol 55. issue 2. 1973-08-28. PMID:4351629. |
cholinergic neurons: effect of acute septal lesion on acetylcholine and choline content of rat hippocampus. |
1973-08-28 |
2023-08-11 |
rat |
| P R Lewis, C C Shute, A Silve. Confirmation from choline acetylase analyses of a massive cholinergic innervation to the rat hippocampus. The Journal of physiology. vol 191. issue 1. 1967-12-14. PMID:6050620. |
confirmation from choline acetylase analyses of a massive cholinergic innervation to the rat hippocampus. |
1967-12-14 |
2023-08-12 |
rat |