| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Lindamood, B K Colasant. Involvement of brain monoamines in the delta-9-tetrahydrocannabinol-induced reduction of hippocampal choline uptake. Journal of neurochemistry. vol 37. issue 3. 1981-11-18. PMID:6268755. |
involvement of brain monoamines in the delta-9-tetrahydrocannabinol-induced reduction of hippocampal choline uptake. |
1981-11-18 |
2023-08-12 |
rat |
| C Lindamood, B K Colasant. Involvement of brain monoamines in the delta-9-tetrahydrocannabinol-induced reduction of hippocampal choline uptake. Journal of neurochemistry. vol 37. issue 3. 1981-11-18. PMID:6268755. |
although removal of serotonergic and noradrenergic input did not alter hippocampal choline uptake relative to the contralateral control side, dopaminergic input reduction produced a significant elevation. |
1981-11-18 |
2023-08-12 |
rat |
| C Rauca, E Kammerer, H Matthie. Influence of choline, hemicholinium-3 and naphthylvinylpyridine on uptake and acetylation of 3H-labeled choline into hippocampus slices. Biochemical pharmacology. vol 30. issue 12. 1981-10-14. PMID:7271837. |
influence of choline, hemicholinium-3 and naphthylvinylpyridine on uptake and acetylation of 3h-labeled choline into hippocampus slices. |
1981-10-14 |
2023-08-12 |
Not clear |
| C R Mantione, A Fisher, I Hani. The AF64a-treated mouse: possible model for central cholinergic hypofunction. Science (New York, N.Y.). vol 213. issue 4507. 1981-08-27. PMID:6894649. |
a loss in the number of functional, sodium ion-dependent, high-affinity choline transport sites was observed in the cortex and hippocampus of mice given an intracerebroventricular injection of 65 nanomoles of af64a (ethylcholine mustard aziridinium ion) 3 days earlier. |
1981-08-27 |
2023-08-12 |
mouse |
| M Shimad. Alteration of acetylcholine synthesis in mouse brain cortex in mild hypoxic hypoxia. Journal of neural transmission. vol 50. issue 2-4. 1981-08-20. PMID:7241118. |
acetylcholine synthesis in four brain regions (cerebral neocortex, hippocampus, septum and striatum) of the mouse during mild hypoxic hypoxia was measured by using [u-14c]glucose and [2h4]choline. |
1981-08-20 |
2023-08-12 |
mouse |
| L J Botticelli, R J Wurtma. Choline reverses naloxone-induced decreases in hippocampal acetylcholine content and suppresses escape behavior in opiate-dependent rats. Brain research. vol 210. issue 1-2. 1981-07-23. PMID:7194720. |
choline reverses naloxone-induced decreases in hippocampal acetylcholine content and suppresses escape behavior in opiate-dependent rats. |
1981-07-23 |
2023-08-12 |
rat |
| M Suzuki, C Nitsch, W Wunn, B Schmude, P Hau. Selected ion monitoring determination of acetylcholine during methoxypyridoxine seizures. Biomedical mass spectrometry. vol 7. issue 11-12. 1981-07-23. PMID:7225535. |
no significant difference was observed in the concentration of acetylcholine in the frontal cortex, cerebellar cortex, septum, hippocampus, or caudate of seizure versus control animals; septal choline increased, however. |
1981-07-23 |
2023-08-12 |
Not clear |
| J M Gorell, C P Navarro, S P Schwendne. Regional CNS levels of acetylcholine and choline during hypoglycemic stupor and recovery. Journal of neurochemistry. vol 36. issue 1. 1981-04-24. PMID:7463059. |
during insulin stupor in mice, acetylcholine levels in cerebral cortex, cerebellum, brainstem, striatum, and hippocampus were unchanged from control values despite brain glucose concentrations 3-10% of normal, whereas choline levels rose 2.4-3.6-fold in all five cns regions. |
1981-04-24 |
2023-08-12 |
mouse |
| D K Riker, R H Roth, X O Breakefiel. High-affinity [3H]choline accumulation in cultured human skin fibroblasts. Journal of neurochemistry. vol 36. issue 2. 1981-04-13. PMID:6257859. |
high-affinity choline accumulation (haca) has been demonstrated in synaptosomes made from cholinergic brain regions such as the hippocampus and caudate-putamen. |
1981-04-13 |
2023-08-12 |
human |
| T E Robinson, D J Gree. Effects of hemicholinium-3 and choline on hippocampal electrical activity during immobility vs. movement. Electroencephalography and clinical neurophysiology. vol 50. issue 3-4. 1981-03-27. PMID:6160973. |
effects of hemicholinium-3 and choline on hippocampal electrical activity during immobility vs. movement. |
1981-03-27 |
2023-08-12 |
rat |
| C K Atterwil. Lack of effect of repeated electroconvulsive shock on [3H]spiroperidol and [2H]5-hydroxytryptamine binding and cholinergic parameters in rat brain. Journal of neurochemistry. vol 35. issue 3. 1981-03-27. PMID:7452284. |
sodium-dependent high affinity [3h]choline uptake (hauc) and chat were also unaltered in striatal and hippocampal samples following repeated ecs. |
1981-03-27 |
2023-08-12 |
rat |
| S A Eckernäs, L Sahlström, S M Aquiloniu. Effects of atropine treatment on cortical, striatal and hippocampal high-affinity uptake of choline in the mouse. Life sciences. vol 27. issue 8. 1980-11-24. PMID:7412492. |
effects of atropine treatment on cortical, striatal and hippocampal high-affinity uptake of choline in the mouse. |
1980-11-24 |
2023-08-12 |
mouse |
| C Rauca, E Kammerer, H Matthie. Choline uptake and permanent memory storage. Pharmacology, biochemistry, and behavior. vol 13. issue 1. 1980-10-27. PMID:7403217. |
the level of high affinity uptake of choline into hippocampus slices may serve as an indicator of the cholinergic activity in this structure under in vitro conditions. |
1980-10-27 |
2023-08-12 |
Not clear |
| A V Revuelta, D L Cheney, E Costa, N Lander, R Mechoula. Reduction of hippocampal acetylcholine turnover in rats treated with (-)-delta 8-tetrahydrocannabinol and its 1',2'-dimethyl-heptyl homolog. Brain research. vol 195. issue 2. 1980-10-24. PMID:6249445. |
the data demonstrate that (-)-delta 8-thc-dmh, (-)-delta 9-thc and (-)- delta 8-thc all specifically reduce ther turnover rate of acetylcholine in the hippocampus in a dose-dependent manner ((-)-delta 8-thc-dmh > (-)-delta 9-thc > (-)-delta 8-thc) without altering the acetylcholine or choline content (except for high doses of (-)-delta 8-thc-dmh). |
1980-10-24 |
2023-08-12 |
rat |
| C Lindamood, B K Colasant. Effects of delta 9-tetrahydrocannabinol and cannabidiol on sodium-dependent high affinity choline uptake in the rat hippocampus. The Journal of pharmacology and experimental therapeutics. vol 213. issue 2. 1980-06-27. PMID:6245205. |
effects of delta 9-tetrahydrocannabinol and cannabidiol on sodium-dependent high affinity choline uptake in the rat hippocampus. |
1980-06-27 |
2023-08-12 |
rat |
| C Lindamood, B K Colasant. Effects of delta 9-tetrahydrocannabinol and cannabidiol on sodium-dependent high affinity choline uptake in the rat hippocampus. The Journal of pharmacology and experimental therapeutics. vol 213. issue 2. 1980-06-27. PMID:6245205. |
doses of delta 9-tetrahydrocannabinol (delta 9-thc) and cannabidiol (cbd) affording the same degree of protection against seizures induced by maximal electroshock were compared for their effects on sodium-dependent high affinity choline uptake into six rat brain regions: cortex, striatum, medulla-pons, hypothalamus, midbrain and hippocampus. |
1980-06-27 |
2023-08-12 |
rat |
| C Lindamood, B K Colasant. Effects of delta 9-tetrahydrocannabinol and cannabidiol on sodium-dependent high affinity choline uptake in the rat hippocampus. The Journal of pharmacology and experimental therapeutics. vol 213. issue 2. 1980-06-27. PMID:6245205. |
in contrast, 1 hr after administration of delta 9-thc, 10 mg/kg i.p., in vitro choline uptake in hippocampus and hypothalamus was significantly reduced. |
1980-06-27 |
2023-08-12 |
rat |
| C Lindamood, B K Colasant. Effects of delta 9-tetrahydrocannabinol and cannabidiol on sodium-dependent high affinity choline uptake in the rat hippocampus. The Journal of pharmacology and experimental therapeutics. vol 213. issue 2. 1980-06-27. PMID:6245205. |
moreover, in vivo administration of delta 9-thc was followed by a dose-related reduction in in vitro hippocampus choline uptake. |
1980-06-27 |
2023-08-12 |
rat |
| C Lindamood, B K Colasant. Effects of delta 9-tetrahydrocannabinol and cannabidiol on sodium-dependent high affinity choline uptake in the rat hippocampus. The Journal of pharmacology and experimental therapeutics. vol 213. issue 2. 1980-06-27. PMID:6245205. |
kinetic analysis of hippocampal choline uptake after administration of delta 9-thc, 10 mg/kg i.p., indicated that there was a reduction in vmax with no change in the km of the transport system. |
1980-06-27 |
2023-08-12 |
rat |
| C Lindamood, B K Colasant. Effects of delta 9-tetrahydrocannabinol and cannabidiol on sodium-dependent high affinity choline uptake in the rat hippocampus. The Journal of pharmacology and experimental therapeutics. vol 213. issue 2. 1980-06-27. PMID:6245205. |
after direct addition to the hippocampal homogenates (in vitro) both delta 9-thc and cbd inhibited choline uptake, with ic50 values of 4.6 and 15.9 microm, respectively. |
1980-06-27 |
2023-08-12 |
rat |